Activation of D2 Dopamine Receptors in CD133+ve Cancer Stem Cells in Non-small Cell Lung Carcinoma Inhibits Proliferation, Clonogenic Ability, and Invasiveness of These Cells

Journal of Biological Chemistry

Volumn 292, Issue 2, 2017, Pages 435-445

  Roy, Soumyabrata ^a   Lu, Kai ^b   Nayak, Mukti Kant ^c   Bhuniya, Avishek ^a   Ghosh, Tithi ^a   Kundu, Suman ^d   Ghosh, Sarbari ^a   Baral, Rathindranath ^a   Dasgupta, Partha Sarathi ^a   Basu, Sujit ^b  

^a CHITTARANJAN NATIONAL CANCER INSTITUTE   (India)

^b OHIO STATE UNIVERSITY   (United States)

^c NATIONAL INSTITUTE OF CHOLERA AND ENTERIC DISEASES   (India)

^d INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; BIOLOGICAL ORGANS; CHEMICAL ACTIVATION; CHEMOTHERAPY; DISEASES; ENZYME ACTIVITY; NEUROPHYSIOLOGY; STEM CELLS; TUMORS;

CANCER STEM CELLS; DOWN-REGULATION; EXTRACELLULAR SIGNAL-REGULATED KINASE; INVASIVENESS; LUNG CARCINOMA; MATRIX METALLOPROTEINASE-9; NON-SMALL CELL LUNG CARCINOMATA; SMALL POPULATION;

CYTOLOGY;

CD133 ANTIGEN; DOPAMINE 2 RECEPTOR; GELATINASE B; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN KINASE B; MAPK1 PROTEIN, HUMAN; MMP9 PROTEIN, HUMAN; POU5F1 PROTEIN, HUMAN; PROM1 PROTEIN, HUMAN; TUMOR PROTEIN;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CANCER STEM CELL; CELL COMPARTMENTALIZATION; CELL INVASION; CELL POPULATION; CELL PROLIFERATION; CLINICAL ARTICLE; CLONOGENESIS; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; LIMIT OF QUANTITATION; LUNG CARCINOGENESIS; MALE; MOUSE; NON SMALL CELL LUNG CANCER; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; PROTEIN TARGETING; A-549 CELL LINE; ANIMAL; BIOSYNTHESIS; CANCER TRANSPLANTATION; GENE EXPRESSION REGULATION; LUNG TUMOR; METABOLISM; NUDE MOUSE; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR INVASION; XENOGRAFT;

A549 CELLS; AC133 ANTIGEN; ANIMALS; CARCINOMA, NON-SMALL-CELL LUNG; CELL PROLIFERATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HETEROGRAFTS; HUMANS; LUNG NEOPLASMS; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 9; MICE; MICE, NUDE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEOPLASM INVASIVENESS; NEOPLASM PROTEINS; NEOPLASM TRANSPLANTATION; NEOPLASTIC STEM CELLS; OCTAMER TRANSCRIPTION FACTOR-3; RECEPTORS, DOPAMINE D2;

EID: 85009771851     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M116.748970     Document Type: Article

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