Prostate cancer stem cells and their potential roles in metastasis

Journal of Surgical Oncology

Volumn 103, Issue 6, 2011, Pages 558-562

  Li, Hangwen ^a,b   Tang, Dean G ^a,c  

^a UNIVERSITY OF TEXAS   (United States)

^b UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^c UNIVERSITY OF TEXAS   (United States)

Author keywords

cancer stem cells; metastasis; prostate cancer; tumor microenvironment

Indexed keywords

ACID PHOSPHATASE PROSTATE ISOENZYME; ALPHA6 INTEGRIN; ANDROGEN RECEPTOR; ANTINEOPLASTIC AGENT; BREAST CANCER RESISTANCE PROTEIN; CD133 ANTIGEN; CD24 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR4 ANTIBODY; CYTOKERATIN 18; CYTOKERATIN 8; HERMES ANTIGEN; OSTEOPONTIN; PROSTATE SPECIFIC ANTIGEN; PROTEIN BCL 2; PROTEIN P63; RECEPTOR ANTIBODY; STEM CELL FACTOR RECEPTOR; TELOMERASE REVERSE TRANSCRIPTASE; UNCLASSIFIED DRUG;

ARTICLE; CANCER STEM CELL; CANCER SURVIVAL; EPITHELIAL MESENCHYMAL TRANSITION; HEMATOPOIETIC STEM CELL; HUMAN; METASTASIS POTENTIAL; MULTIPOTENT STEM CELL; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; STEM CELL; SURVIVAL TIME; TUMOR MICROENVIRONMENT;

HUMANS; MALE; MOLECULAR TARGETED THERAPY; NEOPLASM METASTASIS; NEOPLASTIC STEM CELLS; PROSTATIC NEOPLASMS; TUMOR MICROENVIRONMENT;

EID: 79953872172     PISSN: 00224790     EISSN: 10969098     Source Type: Journal    
DOI: 10.1002/jso.21806     Document Type: Article

References (71)

1. Jemal A, Siegel R, Ward E, et al.: Cancer statistics. CA Cancer J Clin 2008; 58: 71-96.
2. Man YG, Gardner WA,: Bad seeds produce bad crops: A single stage-process of prostate tumor invasion. Int J Biol Sci 2008; 4: 246-258.
3. Feldman BJ, Feldman D,: The development of androgen-independent prostate cancer. Nat Rev Cancer 2001; 1: 34-45. (Pubitemid 33741879)
4. Steeg PS,: Tumor metastasis: Mechanistic insights and clinical challenges. Nat Med 2006; 12: 895904.
5. Al-Hajj M, Wicha MS, Benito-Hernandez A, et al.: Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA 2003; 100: 3983-3988. (Pubitemid 36418143)
6. Singh SK, Hawkins C, Clarke ID, et al.: Identification of human brain tumour initiating cells. Nature 2004; 432: 396-401. (Pubitemid 39551674)
7. O'Brien CA, Pollett A, Gallinger S, et al.: A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 1997; 445: 106-110.
8. Li C, Heidt DG, Dalerba P, et al.: Identification of pancreatic cancer stem cells. Cancer Res 2007; 67: 1030-1037.
9. Tu SM, Lin SH, Logothetis CJ,: Stem-cell origin of metastasis and heterogeneity in solid tumours. Lancet Oncol 2002; 3: 508-513. (Pubitemid 34863672)
10. Wicha MS,: Cancer stem cells and metastasis: Lethal seeds. Clin Cancer Res 2006; 12: 5606-5607. (Pubitemid 44629584)
11. Balic M, Lin H, Young L, et al.: Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype. Clin Cancer Res 2006; 12: 5615-5621. (Pubitemid 44629587)
12. Hermann PC, Huber SL, Herrler T, et al.: Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell Stem Cell 2007; 1: 313-323. (Pubitemid 47355323)
13. Ginestier C, Liu S, Diebel ME, et al.: CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts. J Clin Invest 2010; 120: 485-497.
14. Charafe-Jauffret E, Ginestier C, Iovino F, et al.: Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature. Cancer Res 2009; 69: 1302-1313.
15. Eaton CL, Colombel M, van der Pluijm G, et al.: Evaluation of the frequency of putative prostate cancer stem cells in primary and metastatic prostate cancer. Prostate 2010; 70: 875-882.
16. Hurt EM, Farrar WL,: Cancer stem cells: The seeds of metastasis? Mol Interv 2008; 8: 140-142.
17. Klarmann GJ, Hurt EM, Mathews LA, et al.: Invasive prostate cancer cells are tumor initiating cells that have a stem cell-like genomic signature. Clin Exp Metastasis 2009; 26: 433-446.
18. Li F, Tiede B, Massague J, et al.: Beyond tumorigenesis: Cancer stem cells in metastasis. Cell Res 2007; 17: 3-14. (Pubitemid 46096419)
19. Tang DG, Patrawala L, Calhoun T, et al.: Prostate cancer stem/progenitor cells: Identification, characterization, and implications. Mol Carcinog 2007; 46: 1-14. (Pubitemid 46095228)
20. Patrawala L, Calhoun T, Schneider-Broussard R, et al.: Highly purified CD44+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells. Oncogene 2006; 25: 1696-1708.
21. Patrawala L, Calhoun-Davis T, Schneider-Broussard R, et al.: Hierarchical organization of prostate cancer cells in xenograft tumors: The CD44+alpha2 beta1+ cell population is enriched in tumor-initiating cells. Cancer Res 2007; 67: 6796-6805. (Pubitemid 47105527)
22. Li H, Chen X, Calhoun-Davis T, et al.: PC3 human prostate carcinoma cell holoclones contain self-renewing tumor-initiating cells. Cancer Res 2008; 68: 1820-1825. (Pubitemid 351416567)
23. Li H, Jiang M, Honorio S, et al.: Methodologies in assaying prostate cancer stem cells. Methods Mol Biol 2009; 568: 85-138.
24. Lawson DA, Witte ON,: Stem cells in prostate cancer initiation and progression. J Clin Invest 2007; 117: 2044-2050. (Pubitemid 47219544)
25. Abate-Shen C, Shen MM,: Molecular genetics of prostate cancer. Genes Dev 2000; 14: 2410-2434.
26. Palapattu GS, Wu C, Silvers CR, et al.: Selective expression of CD44, a putative prostate cancer stem cell marker, in neuroendocrine tumor cells of human prostate cancer. Prostate 2009; 69: 78798.
27. Weissman IL,: Stem cells: Units of development, units of regeneration, and units in evolution. Cell 2000; 100: 57-68.
28. English HF, Santen RJ, Isaacs JT,: Response of glandular versus basal rat ventral prostatic epithelial cells to androgen withdrawal and replacement. Prostate 1987; 11: 229-242. (Pubitemid 18004762)
29. Richardson GD, Robson CN, Lang SH, et al.: CD133, a novel marker for human prostatic epithelial stem cells. J Cell Sci 2004; 117: 3539-3545. (Pubitemid 39206394)
30. Leong KG, Wang BE, Johnson L, et al.: Generation of a prostate from a single adult stem cell. Nature 2008; 456: 804-808.
31. Wang X, Kruithof-de Julio M, Economides KD, et al.: A luminal epithelial stem cell that is a cell of origin for prostate cancer. Nature 2009; 461: 495-500.
32. Liu AY, True LD, LaTray L, et al.: Cell-cell interaction in prostate gene regulation and cytodifferentiation. Proc Natl Acad Sci USA 1997; 94: 10705-10710. (Pubitemid 27430798)
33. Tsujimura A, Koikawa Y, Salm S, et al.: Proximal location of mouse prostate epithelial stem cells: A model of prostatic homeostasis. J Cell Biol 2002; 157: 1257-1265. (Pubitemid 34851270)
34. Mills AA, Qi Y, Bradley A,: Conditional inactivation of p63 by Cre-mediated excision. Genesis 2002; 32: 138-141. (Pubitemid 34211720)
35. Bhatia B, Tang S, Yang P, et al.: Cell-autonomous induction of functional tumor suppressor 15lipoxygenase 2 (15-LOX2) contributes to replicative senescence of human prostate progenitor cells. Oncogene 2005; 24: 3583-3595. (Pubitemid 40756228)
36. Reya T, Morrison SJ, Clarke MF, et al.: Stem cells, cancer, and cancer stem cells. Nature 2001; 414: 105-111. (Pubitemid 33041634)
37. Bonnet D, Dick JE,: Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 1997; 3: 730-737. (Pubitemid 27298715)
38. Pece S, Tosoni D, Confalonieri S, et al.: Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content. Cell 2010; 140: 62-73.
39. Qin J, et al.: Manuscript in preparation.
40. Collins AT, Berry PA, Hyde C, et al.: Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res 2005; 65: 10946-10951. (Pubitemid 41713363)
41. Patrawala L, Calhoun T, Schneider-Broussard R, et al.: Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2-cancer cells are similarly tumorigenic. Cancer Res 2005; 65: 6207-6219. (Pubitemid 40994406)
42. Pfeiffer MJ, Schalken JA,: Stem cell characteristics in prostate cancer cell lines. Eur Urol 2010; 57: 246-254.
43. Shackleton M, Quintana E, Fearon ER, et al.: Heterogeneity in cancer: Cancer stem cells versus clonal evolution. Cell 2009; 138: 822-829.
44. Fialkow PJ, Jacobson RJ, Papayannopoulou T,: Chronic myelocytic leukemia: Clonal origin in a stem cell common to the granulocyte, erythrocyte, platelet and monocyte/macrophage. Am J Med 1977; 63: 125-130. (Pubitemid 8146659)
45. Krivtsov AV, Twomey D, Feng Z, et al.: Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9. Nature 2006; 442: 818-822. (Pubitemid 44258912)
46. Wang JC,: Good cells gone bad: The cellular origins of cancer. Trends Mol Med 2010; 16: 145-151.
47. June CH,: Adoptive T cell therapy for cancer in the clinic. J Clin Invest 2007; 117: 1466-1476. (Pubitemid 46871329)
48. Rizvi AZ, Swain JR, Davies PS, et al.: Bone marrow-derived cells fuse with normal and transformed intestinal stem cells. Proc Natl Acad Sci USA 2006; 103: 6321-6325.
49. Werbowetski-Ogilvie TE, Bhatia M,: Pluripotent human stem cell lines: What we can learn about cancer initiation. Trends Mol Med 2008; 14: 323-332.
50. Hermann PC, Huber SL, Heeschen C,: Metastatic cancer stem cells: A new target for anti-cancer therapy? Cell Cycle 2008; 7: 188-193. (Pubitemid 351366518)
51. Glinsky GV,: Death-from-cancer signatures and stem cell contribution to metastatic cancer. Cell Cycle 2005; 4: 1171-1175. (Pubitemid 41365385)
52. Glinsky GV, Berezovska O, Glinskii AB,: Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer. J Clin Invest 2005; 115: 503-521.
53. Ben-Porath I, Thomson MW, Carey VJ, et al.: An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nat Genet 2008; 40: 499-507. (Pubitemid 351601215)
54. Fidler IJ, Talmadge JE,: Evidence that intravenously derived murine pulmonary melanoma metastases can originate from the expansion of a single tumor cell. Cancer Res 1986; 46: 5167-5171. (Pubitemid 16008283)
55. Mani SA, Guo W, Liao MJ, et al.: The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2008; 133: 704-715. (Pubitemid 351636299)
56. Barnhart BC, Simon MC,: Metastasis and stem cell pathways. Cancer Metastasis Rev 2007; 26: 261-271. (Pubitemid 47101658)
57. Fidler IJ,: The pathogenesis of cancer metastasis: The 'seed and soil' hypothesis revisited. Nat Rev Cancer 2003; 3: 453-458. (Pubitemid 37328849)
58. Shipitsin M, Campbell LL, Argani P, et al.: Molecular definition of breast tumor heterogeneity. Cancer Cell 2007; 11: 259-273. (Pubitemid 46349843)
59. Shmelkov SV, Butler JM, Hooper AT, et al.: CD133 expression is not restricted to stem cells, and both CD133+ and CD133-metastatic colon cancer cells initiate tumors. J Clin Invest 2008; 118: 2111-2120. (Pubitemid 351872330)
60. Weigelt B, Peterse JL, van't Veer LJ,: Breast cancer metastasis: Markers and models. Nat Rev Cancer 2005; 5: 591-602. (Pubitemid 41081385)
61. Mimeault M, Batra SK,: Functions of tumorigenic and migrating cancer progenitor cells in cancer progression and metastasis and their therapeutic implications. Cancer Metastasis Rev 2007; 26: 203-214. (Pubitemid 46452192)
62. Polyak K,: Breast cancer: Origins and evolution. J Clin Invest 2007; 117: 3155-3163. (Pubitemid 350096968)
63. Campbell LL, Polyak K,: Breast tumor heterogeneity: Cancer stem cells or clonal evolution? Cell Cycle 2007; 6: 2332-2338. (Pubitemid 350058682)
64. Singh D, Febbo PG, Ross K, et al.: Gene expression correlates of clinical prostate cancer behavior. Cancer Cell 2002; 1: 203-209. (Pubitemid 41039166)
65. Minn AJ, Gupta GP, Siegel PM, et al.: Genes that mediate breast cancer metastasis to lung. Nature 2005; 436: 518-524. (Pubitemid 41112921)
66. Scheel C, Onder T, Karnoub A, et al.: Adaptation versus selection: The origins of metastatic behavior. Cancer Res 2007; 67: 11476-11479.
67. Kang Y,: Analysis of cancer stem cell metastasis in xenograft animal models. Methods Mol Biol 2009; 568: 7-19.
68. Killion JJ, Radinsky R, Fidler IJ,: Orthotopic models are necessary to predict therapy of transplantable tumors in mice. Cancer Metastasis Rev 1998-1999; 17: 279-284. (Pubitemid 29210167)
69. Stephenson RA, Dinney CP, Gohji K, et al.: Metastatic model for human prostate cancer using orthotopic implantation in nude mice. J Natl Cancer Inst 1992; 84: 951-957.
70. Hoffman RM,: Whole-body fluorescence imaging with green fluorescence protein. Methods Mol Biol 2002; 183: 135-148.
71. Dubrovska A, Kim S, Salamone RJ, et al.: The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations. Proc Natl Acad Sci USA 2009; 106: 268-273.