Intracellularly swollen polypeptide nanogel assists hepatoma chemotherapy

Theranostics

Volumn 7, Issue 3, 2017, Pages 703-716

  Shi, Bo ^a   Huang, Kexin ^a   Ding, Jianxun ^b   Xu, Weiguo ^b   Yang, Yu ^a   Liu, Haiyan ^a   Yan, Lesan ^c   Chen, Xuesi ^b  

^a JILIN UNIVERSITY   (China)

^b CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY   (China)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Hepatoma chemotherapy; Intracellular drug delivery; Polypeptide nanogel; Stimuli responsiveness

Indexed keywords

DOXORUBICIN; ANTINEOPLASTIC AGENT; DRUG CARRIER; MACROGOL DERIVATIVE; NANOGEL; PEPTIDE; POLYETHYLENEIMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; AREA UNDER THE CURVE; ARTICLE; BODY WEIGHT; BONE MARROW CELL; CANCER INHIBITION; CELL PROLIFERATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG CYTOTOXICITY; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG ELIMINATION; DRUG FORMULATION; DRUG HALF LIFE; DRUG RELEASE; DRUG SAFETY; DRUG UPTAKE; DUAL RESPONSIVE POLYPEPTIDE NANOGEL; FEMALE; GEL; HEPATOCELLULAR CARCINOMA CELL LINE; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; IN VIVO STUDY; LEUKOCYTE COUNT; LIVER CELL CARCINOMA; MALE; MAXIMUM PLASMA CONCENTRATION; MICRONUCLEUS; MOUSE; NANOENCAPSULATION; NONHUMAN; PARTICLE SIZE; PH; RAT; TIME TO MAXIMUM PLASMA CONCENTRATION; WEIGHT REDUCTION; ANIMAL; BAGG ALBINO MOUSE; CARCINOMA, HEPATOCELLULAR; DISEASE MODEL; OXIDATION REDUCTION REACTION; PROCEDURES; TREATMENT OUTCOME;

ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOMA, HEPATOCELLULAR; DISEASE MODELS, ANIMAL; DOXORUBICIN; DRUG CARRIERS; DRUG THERAPY; HYDROGEN-ION CONCENTRATION; MICE; MICE, INBRED BALB C; OXIDATION-REDUCTION; PEPTIDES; POLYETHYLENE GLYCOLS; POLYETHYLENEIMINE; TREATMENT OUTCOME;

EID: 85009726312     PISSN: None     EISSN: 18387640     Source Type: Journal    
DOI: 10.7150/thno.16794     Document Type: Article

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