Acid-labile boronate-bridged dextran-bortezomib conjugate with up-regulated hypoxic tumor suppression

Chemical Communications

Volumn 51, Issue 31, 2015, Pages 6812-6815

  Xu, Weiguo ^a   Ding, Jianxun ^a   Li, Lingyu ^a   Xiao, Chunsheng ^a   Zhuang, Xiuli ^a   Chen, Xuesi ^a  

^a CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BORONIC ACID DERIVATIVE; BORTEZOMIB; DEXTRAN; ANTINEOPLASTIC AGENT; DRUG CARRIER;

ACIDITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; ENDOSOME; ESTERIFICATION; GLUCOSE BLOOD LEVEL; IN VITRO STUDY; INFRARED SPECTROSCOPY; INTERNALIZATION; LIGHT SCATTERING; MASS SPECTROMETRY; PROTON NUCLEAR MAGNETIC RESONANCE; SPECTROPHOTOMETRY; TISSUE ENGINEERING; TRANSMISSION ELECTRON MICROSCOPY; TUMOR MICROENVIRONMENT; UPREGULATION; ANIMAL; APOPTOSIS; CELL HYPOXIA; CHEMISTRY; DRUG EFFECTS; DRUG RELEASE; HUMAN; MOUSE; PH; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BORONIC ACIDS; BORTEZOMIB; CELL HYPOXIA; CELL LINE, TUMOR; DEXTRANS; DRUG CARRIERS; DRUG LIBERATION; ESTERIFICATION; HUMANS; HYDROGEN-ION CONCENTRATION; MICE; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84926628928     PISSN: 13597345     EISSN: 1364548X     Source Type: Journal    
DOI: 10.1039/c5cc01371b     Document Type: Article

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