Nlrp3 Activation Induces Il-18 Synthesis and Affects the Epithelial Barrier Function in Reactive Cholangiocytes

American Journal of Pathology

Volumn 187, Issue 2, 2017, Pages 366-376

  Maroni, Luca ^a   Agostinelli, Laura ^a   Saccomanno, Stefania ^a   Pinto, Claudio ^a   Giordano, Debora M ^a   Rychlicki, Chiara ^a   De Minicis, Samuele ^a   Trozzi, Luciano ^a   Banales, Jesus M ^b   Melum, Espen ^c,d   Karlsen, Tom H ^c,d   Benedetti, Antonio ^a   Baroni, Gianluca Svegliati ^a   Marzioni, Marco ^a  

^a UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^b BIODONOSTIA HEALTH RESEARCH INSTITUTE   (Spain)

^c OSLO UNIVERSITY HOSPITAL   (Norway)

^d UNIVERSITY OF OSLO   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIHYDRO 2,4,6 TRIMETHYL 3,5 PYRIDINEDICARBOXYLIC ACID DIETHYL ESTER; ADENOSINE TRIPHOSPHATE; CRYOPYRIN; CYTOKERATIN 19; INTERLEUKIN 18; LIPOPOLYSACCHARIDE; PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; UVOMORULIN; ZONULIN 1; INFLAMMASOME;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE PERMEABILITY; CELL PROLIFERATION; CHOLANGIOCYTE; CONTROLLED STUDY; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LIVER INJURY; MOUSE; NONHUMAN; PATHOGENESIS; PRIMARY SCLEROSING CHOLANGITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RAT; ANIMAL; BIOSYNTHESIS; IMMUNOBLOTTING; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; SCLEROSING CHOLANGITIS;

ANIMALS; CHOLANGITIS, SCLEROSING; HUMANS; IMMUNOBLOTTING; INFLAMMASOMES; INTERLEUKIN-18; MICE; MICE, KNOCKOUT; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 85009450718     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2016.10.010     Document Type: Article

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