Lipopolysaccharide (LPS)-induced biliary epithelial cell NRas activation requires Epidermal Growth Factor Receptor (EGFR)

PLoS ONE

Volumn 10, Issue 4, 2015, Pages

  Trussoni, Christy E ^a   Tabibian, James H ^a   Splinter, Patrick L ^a   O'Hara, Steven P ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAM PROTEIN; ADAM17 PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; N RAS PROTEIN; RAS PROTEIN; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME INHIBITOR; UNCLASSIFIED DRUG; ADAM17 PROTEIN, HUMAN; ADAM17 PROTEIN, MOUSE; EGFR PROTEIN, HUMAN; EGFR PROTEIN, MOUSE; ENZYME INHIBITOR; GUANOSINE TRIPHOSPHATASE; MEMBRANE PROTEIN; NRAS PROTEIN, HUMAN; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE DUCT; CELL PROLIFERATION; CHOLANGIOCYTE; CONTROLLED STUDY; ENZYME ACTIVATION; FLUORESCENCE RESONANCE ENERGY TRANSFER; HEPATITIS C; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; IN VITRO STUDY; INTRACELLULAR SIGNALING; MOUSE; NONHUMAN; PRIMARY BILIARY CIRRHOSIS; PRIMARY SCLEROSING CHOLANGITIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CYTOLOGY; DIGESTIVE SYSTEM DISEASE; DRUG EFFECTS; EPITHELIUM CELL; GENETICS; LIVER; METABOLISM; PATHOLOGY; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

HEPATITIS C VIRUS;

ADAM PROTEINS; ADAM17 PROTEIN; ANIMALS; BILE DUCTS; CELL PROLIFERATION; CELLS, CULTURED; DIGESTIVE SYSTEM DISEASES; ENZYME INHIBITORS; EPITHELIAL CELLS; GTP PHOSPHOHYDROLASES; HUMANS; LIPOPOLYSACCHARIDES; LIVER; MEMBRANE PROTEINS; MICE; PHOSPHORYLATION; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION;

EID: 84928533791     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0125793     Document Type: Article

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