Zonulin as prehaptoglobin2 regulates lung permeability and activates the complement system

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 304, Issue 12, 2013, Pages

  Rittirsch, Daniel ^a,b   Flierl, Michael A ^a,c   Nadeau, Brian A ^a   Day, Danielle E ^a   Huber Lang, Markus S ^d   Grailer, Jamison J ^a   Zetoune, Firas S ^a   Andjelkovic, Anuska V ^a   Fasano, Alessio ^e   Ward, Peter A ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY HOSPITAL ULM   (Germany)

^e UNIVERSITY OF MARYLAND   (United States)

Author keywords

Acute lung injury; C3a; C5a; Inflammation; Tight junctions

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; COMPLEMENT COMPONENT C3A; COMPLEMENT COMPONENT C5A; HAPTOGLOBIN; IMMUNOGLOBULIN G; UNCLASSIFIED DRUG; ZONULIN PROTEIN;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPLEMENT SYSTEM; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENDOTHELIUM CELL; EPITHELIUM CELL; IMMUNE COMPLEX DEPOSITION; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TIGHT JUNCTION;

ACUTE LUNG INJURY; C3A; C5A; INFLAMMATION; TIGHT JUNCTIONS;

ACUTE LUNG INJURY; ANIMALS; ANTIGEN-ANTIBODY COMPLEX; CHOLERA TOXIN; COMPLEMENT ACTIVATION; COMPLEMENT SYSTEM PROTEINS; CYTOKINES; GENE EXPRESSION REGULATION; IMMUNOGLOBULIN G; LUNG; MALE; MICE; MICE, INBRED C57BL; NEUTROPHILS; OLIGOPEPTIDES; PEPTIDES; PERMEABILITY; PROTEIN PRECURSORS; SIGNAL TRANSDUCTION; TIGHT JUNCTIONS; TRACHEA;

EID: 84879191234     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00196.2012     Document Type: Article

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