Plasma mitochondrial DNA levels were independently associated with lung injury in elderly hip fracture patients

Injury

Volumn 48, Issue 2, 2017, Pages 454-459

  Zhang, Jian zheng ^a   Wang, Juan ^a   Qu, Wen chun ^b   Wang, Xiao wei ^a   Liu, Zhi ^a   Ren, Ji xin ^a   Han, Li ^a   Sun, Tian sheng ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b MAYO CLINIC   (United States)

Author keywords

Hip fracture; Lung injury; Mitochondrial DNA; Predictor; Surgery; Systemic inflammatory response syndrome

Indexed keywords

BIOLOGICAL MARKER; INTERLEUKIN 10; INTERLEUKIN 6; MITOCHONDRIAL DNA; PROSTAGLANDIN E2;

AGED; ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; FEMALE; FEMUR INTERTROCHANTERIC FRACTURE; FOLLOW UP; GERIATRIC PATIENT; HUMAN; LUNG INJURY; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROGNOSIS; PROSPECTIVE STUDY; RISK ASSESSMENT; SURGICAL MORTALITY; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; BLOOD; CHINA; COMPLICATION; EPIDEMIOLOGY; HIP FRACTURE; IMMUNOLOGY; PATHOPHYSIOLOGY; PREDICTIVE VALUE;

AGED; CHINA; DINOPROSTONE; DNA, MITOCHONDRIAL; FEMALE; HIP FRACTURES; HUMANS; INTERLEUKIN-10; INTERLEUKIN-6; LUNG INJURY; MALE; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

EID: 85009289233     PISSN: 00201383     EISSN: 18790267     Source Type: Journal    
DOI: 10.1016/j.injury.2017.01.009     Document Type: Article

References (31)

1. [1] Ruths, S., Bakken, M.S., Ranhoff, A.H., Hunskaar, S., Engesæter, L.B., Engeland, A., Risk of hip fracture among older people using antihypertensive drugs: a nationwide cohort study. BMC Geriatr, 15, 2015, 153.
2. [2] Klop, C., Welsing, P.M., Leufkens, H.G., Elders, P.J., Overbeek, J.A., van den Bergh, J.P., et al. The epidemiology of hip and major osteoporotic fractures in a Dutch population of community-dwelling elderly: implications for the Dutch FRAX(R) Algorithm. PLoS One, 10, 2015, e0143800.
3. [3] Robinson, D., Garmo, H., Stattin, P., Michaëlsson, K., Risk of fractures and falls during and after 5-alpha reductase inhibitor use: a nationwide cohort study. PLoS One, 10, 2015, e0140598.
4. [4] Sunol, R., Wagner, C., Arah, O.A., Kristensen, S., Pfaff, H., Klazinga, N., et al. Implementation of departmental quality strategies is positively associated with clinical practice: results of a multicenter study in 73 hospitals in 7 European countries. PLoS One, 10, 2015, e0141157.
5. [5] Schumacker, P.T., Gillespie, M.N., Nakahira, K., Choi, A.M., Crouser, E.D., Piantadosi, C.A., et al. Mitochondria in lung biology and pathology: more than just a powerhouse. Am J Physiol Lung Cell Mol Physiol 306 (2014), L962–L974.
6. [6] Wakasugi, M., Kazama, J.J., Taniguchi, M., Wada, A., Iseki, K., Tsubakihara, Y., et al. Increased risk of hip fracture among Japanese hemodialysis patients. J Bone Miner Metab 31 (2013), 315–321.
7. [7] Yin, X.H., Huang, G.L., Lin, D.R., Wan, C.C., Wang, Y.D., Song, J.K., et al. Exposure to fluoride in drinking water and hip fracture risk: a meta-analysis of observational studies. PLoS One, 10, 2015, e0126488.
8. [8] Bolland, M.J., Grey, A., Gamble, G.D., Reid, I.R., Concordance of results from randomized and observational analyses within the same study: a re-analysis of the women's health initiative limited-access dataset. PLoS One, 10, 2015, e0139975.
9. [9] Caillet, P., Klemm, S., Ducher, M., Aussem, A., Schott, A.M., Hip fracture in the elderly: a re-analysis of the EPIDOS study with causal Bayesian networks. PLoS One, 10, 2015, e0120125.
10. [10] Gan, L., Chen, X., Sun, T., Li, Q., Zhang, R., Zhang, J., et al. Significance of serum mtDNA concentration in lung injury induced by hip fracture. Shock 44 (2015), 52–57.
11. [11] Gan, L., Zhong, J., Zhang, R., Sun, T., Li, Q., Chen, X., et al. The immediate intramedullary nailing surgery increased the mitochondrial DNA release that aggravated systemic inflammatory response and lung injury induced by elderly hip fracture. Mediat Inflamm, 2015, 2015, 587378.
12. [12] Zhang, Q., Itagaki, K., Hauser, C.J., Mitochondrial DNA is released by shock and activates neutrophils via p38 map kinase. Shock 34 (2010), 55–59.
13. [13] McIlroy, D.J., Bigland, M., White, A.E., Hardy, B.M., Lott, N., Smith, D.W., et al. Cell necrosis-independent sustained mitochondrial and nuclear DNA release following trauma surgery. J Trauma Acute Care Surg 78 (2015), 282–288.
14. [14] Hao, Z., Tiansheng, S., Zhi, L., Jianzheng, Z., Xiaowei, W., Jia, L., Hip fracture aggravates systemic inflammation and lung injury in aged chronic cigarette smoke exposed rats. J Orthop Res 32 (2014), 24–30.
15. [15] Gu, X., Yao, Y., Wu, G., Lv, T., Luo, L., Song, Y., The plasma mitochondrial DNA is an independent predictor for post-traumatic systemic inflammatory response syndrome. PLoS One, 8, 2013, e72834.
16. [16] Bauman, Z.M., Gassner, M.Y., Coughlin, M.A., Mahan, M., Watras, J., Lung injury prediction score is useful in predicting acute respiratory distress syndrome and mortality in surgical critical care patients. Crit Care Res Pract, 2015, 2015, 157408.
17. [17] Sun, S., Sursal, T., Adibnia, Y., Zhao, C., Zheng, Y., Li, H., et al. Mitochondrial DAMPs increase endothelial permeability through neutrophil dependent and independent pathways. PLoS One, 8, 2013, e59989.
18. [18] Walko, T.D. 3rd, Bola, R.A., Hong, J.D., Au, A.K., Bell, M.J., Kochanek, P.M., et al. Cerebrospinal fluid mitochondrial DNA: a novel DAMP in pediatric traumatic brain injury. Shock 41 (2014), 499–503.
19. [19] Hassani, S., Lindman, A.S., Kristoffersen, D.T., Tomic, O., Helgeland, J., 30-Day survival probabilities as a quality indicator for norwegian hospitals: data management and analysis. PLoS One, 10, 2015, e0136547.
20. [20] Sun, T., Wang, X., Liu, Z., Chen, X., Zhang, J., Plasma concentrations of pro- and anti-inflammatory cytokines and outcome prediction in elderly hip fracture patients. Injury 42 (2011), 707–713.
21. [21] Itagaki, K., Kaczmarek, E., Lee, Y.T., Tang, I.T., Isal, B., Adibnia, Y., et al. Mitochondrial DNA released by trauma induces neutrophil extracellular traps. PLoS One, 10, 2015, e0120549.
22. [22] Puskarich, M.A., Shapiro, N.I., Trzeciak, S., Kline, J.A., Jones, A.E., Plasma levels of mitochondrial DNA in patients presenting to the emergency department with sepsis. Shock 38 (2012), 337–340.
23. [23] Kuck, J.L., Obiako, B.O., Gorodnya, O.M., Pastukh, V.M., Kua, J., Simmons, J.D., et al. Mitochondrial DNA damage-associated molecular patterns mediate a feed-forward cycle of bacteria-induced vascular injury in perfused rat lungs. Am J Physiol Lung Cell Mol Physiol 308 (2015), L1078–85.
24. [24] McIlroy, D.J., Jarnicki, A.G., Au, G.G., Lott, N., Smith, D.W., Hansbro, P.M., et al. Mitochondrial DNA neutrophil extracellular traps are formed after trauma and subsequent surgery. J Crit Care, 29, 2014, 1133 e1-5.
25. [25] Zhang, J.Z., Liu, Z., Liu, J., Ren, J.X., Sun, T.S., Mitochondrial DNA induces inflammation and increases TLR9/NF-kappaB expression in lung tissue. Int J Mol Med 33 (2014), 817–824.
26. [26] Sun, T., Wang, X., Liu, Z., Chen, X., Zhang, J., Plasma concentrations of pro- and anti-inflammatory cytokines and outcome prediction in elderly hip fracture patients. Injury 42 (2011), 707–713.
27. [27] He, J., Lu, Y., Xia, H., Liang, Y., Wang, X., Bao, W., et al. Circulating mitochondrial damps are not effective inducers of proteinuria and kidney injury in rodents. PLoS One, 10, 2015, e0124469.
28. [28] Li, H., Itagaki, K., Sandler, N., Gallo, D., Galenkamp, A., Kaczmarek, E., et al. Mitochondrial damage-associated molecular patterns from fractures suppress pulmonary immune responses via formyl peptide receptors 1 and 2. J Trauma Acute Care Surg 78 (2015), 272–279 discussion 279-281.
29. [29] Li, S.G., Sun, T.S., Liu, Z., Ren, J.X., Liu, B., Gao, Y., Factors influencing postoperative mortality one year after surgery for hip fracture in Chinese elderly population. Chin Med J (Engl) 126 (2013), 2715–2719.
30. [30] Prikhodko, A.S., Shabanov, A.K., Zinovkina, L.A., Popova, E.N., Aznauryan, M.A., Lanina, N.O., et al. Pure mitochondrial DNA does not activate human neutrophils in vitro. Biochemistry (Mosc) 80 (2015), 629–635.
31. [31] Hauser, C.J., Sursal, T., Rodriguez, E.K., Appleton, P.T., Zhang, Q., Itagaki, K., Mitochondrial damage associated molecular patterns from femoral reamings activate neutrophils through formyl peptide receptors acnd P44/42 MAP kinase. J Orthop Trauma 24 (2010), 534–538.