메뉴 건너뛰기




Volumn 10, Issue 4, 2015, Pages

Circulating mitochondrial DAMPs are not effective inducers of proteinuria and kidney injury in rodents

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; MITOCHONDRIAL DNA;

EID: 84930670950     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0124469     Document Type: Article
Times cited : (20)

References (42)
  • 1
    • 77955630643 scopus 로고    scopus 로고
    • HMGB1 contributes to kidney ischemia reperfusion injury
    • PMID: 20847143
    • Wu H, Ma J, Wang P, Corpuz TM, Panchapakesan U, Wyburn K, et al. HMGB1 contributes to kidney ischemia reperfusion injury. J Am Soc Nephrol. 2010; 21: 1878-1890. doi: 10.1681/ASN.2009101048 PMID: 20847143
    • (2010) J Am Soc Nephrol , vol.21 , pp. 1878-1890
    • Wu, H.1    Ma, J.2    Wang, P.3    Corpuz, T.M.4    Panchapakesan, U.5    Wyburn, K.6
  • 2
    • 44049098885 scopus 로고    scopus 로고
    • RAGE mediates podocyte injury in adriamycin-induced glomerulosclerosis
    • PMID: 18256352
    • Guo J, Ananthakrishnan R, Qu W, Lu Y, Reiniger N, Zeng S, et al. RAGE mediates podocyte injury in adriamycin-induced glomerulosclerosis. J Am Soc Nephrol. 2008; 19: 961-972. doi: 10.1681/ASN.2007101109 PMID: 18256352
    • (2008) J am Soc Nephrol , vol.19 , pp. 961-972
    • Guo, J.1    Ananthakrishnan, R.2    Qu, W.3    Lu, Y.4    Reiniger, N.5    Zeng, S.6
  • 3
    • 20544441481 scopus 로고    scopus 로고
    • Heat shock protein 60 is released in immune-mediated glomerulonephritis and aggravates disease: In vivo evidence for an immunologic danger signal
    • PMID: 15601747
    • Lang A, Benke D, Eitner F, Engel D, Ehrlich S, Breloer M, et al. Heat shock protein 60 is released in immune-mediated glomerulonephritis and aggravates disease: in vivo evidence for an immunologic danger signal. J Am Soc Nephrol. 2005; 16: 383-391. PMID: 15601747
    • (2005) J Am Soc Nephrol , vol.16 , pp. 383-391
    • Lang, A.1    Benke, D.2    Eitner, F.3    Engel, D.4    Ehrlich, S.5    Breloer, M.6
  • 4
    • 70349492441 scopus 로고    scopus 로고
    • A novel role for uric acid in acute kidney injury associated with tumour lysis syndrome
    • PMID: 19581334
    • Shimada M, Johnson RJ, May WS, Lingegowda V, Sood P, Nakagawa T, et al. A novel role for uric acid in acute kidney injury associated with tumour lysis syndrome. Nephrol Dial Transplant. 2009; 24: 2960-2964. doi: 10.1093/ndt/gfp330 PMID: 19581334
    • (2009) Nephrol Dial Transplant , vol.24 , pp. 2960-2964
    • Shimada, M.1    Johnson, R.J.2    May, W.S.3    Lingegowda, V.4    Sood, P.5    Nakagawa, T.6
  • 5
    • 77949683133 scopus 로고    scopus 로고
    • Extracellular matrix molecules: Endogenous danger signals as new drug targets in kidney diseases
    • PMID: 20045380
    • Schaefer L. Extracellular matrix molecules: endogenous danger signals as new drug targets in kidney diseases. Curr Opin Pharmacol. 2010; 10: 185-190. doi: 10.1016/j.coph.2009.11.007 PMID: 20045380
    • (2010) Curr Opin Pharmacol , vol.10 , pp. 185-190
    • Schaefer, L.1
  • 6
    • 2642573579 scopus 로고    scopus 로고
    • Endogenously oxidized mitochondrial DNA induces in vivo and in vitro inflammatory responses
    • PMID: 14982943
    • Collins LV, Hajizadeh S, Holme E, Jonsson IM, Tarkowski A. Endogenously oxidized mitochondrial DNA induces in vivo and in vitro inflammatory responses. J Leukoc Biol. 2004; 75: 995-1000. PMID: 14982943
    • (2004) J Leukoc Biol , vol.75 , pp. 995-1000
    • Collins, L.V.1    Hajizadeh, S.2    Holme, E.3    Jonsson, I.M.4    Tarkowski, A.5
  • 7
    • 73949118676 scopus 로고    scopus 로고
    • Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome
    • PMID: 19918053
    • Iyer SS, Pulskens WP, Sadler JJ, Butter LM, Teske GJ, Ulland TK, et al. Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome. Proc Natl Acad Sci U S A. 2009; 106: 20388-20393. doi: 10.1073/pnas.0908698106 PMID: 19918053
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 20388-20393
    • Iyer, S.S.1    Pulskens, W.P.2    Sadler, J.J.3    Butter, L.M.4    Teske, G.J.5    Ulland, T.K.6
  • 8
    • 77950275298 scopus 로고    scopus 로고
    • Circulating mitochondrial DAMPs cause inflammatory responses to injury
    • PMID: 20203610
    • Zhang Q, Raoof M, Chen Y, Sumi Y, Sursal T, Junger W, et al. Circulating mitochondrial DAMPs cause inflammatory responses to injury. Nature. 2010; 464: 104-107. doi: 10.1038/nature08780 PMID: 20203610
    • (2010) Nature , vol.464 , pp. 104-107
    • Zhang, Q.1    Raoof, M.2    Chen, Y.3    Sumi, Y.4    Sursal, T.5    Junger, W.6
  • 9
    • 40449113524 scopus 로고    scopus 로고
    • The role of inflammatory cytokines in diabetic nephropathy
    • PMID: 18256353
    • Navarro-González J, Mora-Fernández C. The role of inflammatory cytokines in diabetic nephropathy. J Am Soc Nephrol. 2008; 19:433-442. doi: 10.1681/ASN.2007091048 PMID: 18256353
    • (2008) J Am Soc Nephrol , vol.19 , pp. 433-442
    • Navarro-González, J.1    Mora-Fernández, C.2
  • 10
    • 61649096404 scopus 로고    scopus 로고
    • Microalbuminuria - A biomarker of renal microvascular disease
    • PMID: 19212911
    • Futraku N, Sridama V, Futrakul P. Microalbuminuria - a biomarker of renal microvascular disease. Ren Fail. 2009; 31:140-3. doi: 10.1080/08860220802595948 PMID: 19212911
    • (2009) Ren Fail , vol.31 , pp. 140-143
    • Futraku, N.1    Sridama, V.2    Futrakul, P.3
  • 11
    • 0141539470 scopus 로고    scopus 로고
    • What has the immune system got against the glomerular podocyte?
    • PMID: 12974746
    • Mathieson PW. What has the immune system got against the glomerular podocyte? Clin Exp Immunol. 2003; 134:1-5. PMID: 12974746
    • (2003) Clin Exp Immunol , vol.134 , pp. 1-5
    • Mathieson, P.W.1
  • 12
    • 51849083714 scopus 로고    scopus 로고
    • Overview of factors contributing to the pathophysiology of progressive renal disease
    • PMID: 18650795
    • Schlondorff DO. Overview of factors contributing to the pathophysiology of progressive renal disease. Kidney Int. 2008; 74:860-866. doi: 10.1038/ki.2008.351 PMID: 18650795
    • (2008) Kidney Int , vol.74 , pp. 860-866
    • Schlondorff, D.O.1
  • 13
    • 35349005817 scopus 로고    scopus 로고
    • Innate pathogen recognition in the kidney: Toll-like receptors, NOD-like receptors, and RIGlike helicases
    • PMID: 17653134
    • Anders H. Innate pathogen recognition in the kidney: toll-like receptors, NOD-like receptors, and RIGlike helicases. Kidney Int. 2007; 72:1051-1056. PMID: 17653134
    • (2007) Kidney Int , vol.72 , pp. 1051-1056
    • Anders, H.1
  • 14
    • 77955984085 scopus 로고    scopus 로고
    • The role of innate immunity in septic acute kidney injuries
    • PMID: 20523275
    • Gonçalves GM, Zamboni DS, Câmara NO. The role of innate immunity in septic acute kidney injuries. Shock. 2010; 34 Suppl 1:22-26. doi: 10.1097/SHK.0b013e3181e7e69e PMID: 20523275
    • (2010) Shock , vol.34 , pp. 22-26
    • Gonçalves, G.M.1    Zamboni, D.S.2    Câmara, N.O.3
  • 15
    • 79957773993 scopus 로고    scopus 로고
    • The inflammasomes in kidney disease
    • PMID: 21566058
    • Anders H-J, Muruve DA. The inflammasomes in kidney disease. J Am Soc Nephrol. 2011; 22: 1007-1018. doi: 10.1681/ASN.2010080798 PMID: 21566058
    • (2011) J Am Soc Nephrol , vol.22 , pp. 1007-1018
    • Anders, H.-J.1    Muruve, D.A.2
  • 16
    • 85047691168 scopus 로고    scopus 로고
    • Induction of B7-1 in podocytes is associated with nephrotic syndrome
    • PMID: 15146236
    • Reiser J, von Gersdorff G, Loos M, Oh J, Asanuma K, Giardino L, et al. Induction of B7-1 in podocytes is associated with nephrotic syndrome. J Clin Invest. 2004; 113:1390-1397. PMID: 15146236
    • (2004) J Clin Invest , vol.113 , pp. 1390-1397
    • Reiser, J.1    Von Gersdorff, G.2    Loos, M.3    Oh, J.4    Asanuma, K.5    Giardino, L.6
  • 17
    • 84875138335 scopus 로고    scopus 로고
    • Mitochondrial DAMPs increase endothelial permeability through neutrophil dependent and independent pathways
    • PMID: 23527291
    • Sun S, Sursal T, Adibnia Y, Zhao C, Zheng Y, Li H, et al. Mitochondrial DAMPs increase endothelial permeability through neutrophil dependent and independent pathways. PLoS One. 2013; 8:e59989. doi: 10.1371/journal.pone.0059989 PMID: 23527291
    • (2013) PLoS One , vol.8
    • Sun, S.1    Sursal, T.2    Adibnia, Y.3    Zhao, C.4    Zheng, Y.5    Li, H.6
  • 19
    • 0022977969 scopus 로고
    • Proteinuria following trauma
    • PMID: 2879505
    • Gosling P and Sutcliffe AJ. Proteinuria following trauma. Ann Clin Biochem. 1986; 23: 681-685. PMID: 2879505
    • (1986) Ann Clin Biochem , vol.23 , pp. 681-685
    • Gosling, P.1    Sutcliffe, A.J.2
  • 20
    • 0032709243 scopus 로고    scopus 로고
    • Glomerular permeability and trauma: A correlation between microalbuminuria and Injury Severity Score
    • PMID: 10548189
    • De Gaudio AR, Spina R, Di Filippo A, Feri M. Glomerular permeability and trauma: A correlation between microalbuminuria and Injury Severity Score. Crit Care Med. 1999; 27: 2105-2108. PMID: 10548189
    • (1999) Crit Care Med , vol.27 , pp. 2105-2108
    • De Gaudio, A.R.1    Spina, R.2    Di Filippo, A.3    Feri, M.4
  • 21
    • 69449102358 scopus 로고    scopus 로고
    • Loss of size selectivity of the glomerular filtration barrier in rats following laparotomy and muscle trauma
    • PMID: 19587143
    • Axelsson J, Mahmutovic I, Rippe A, Rippe B. Loss of size selectivity of the glomerular filtration barrier in rats following laparotomy and muscle trauma. Am J Physiol Renal Physiol. 2009; 297: F577-F582. doi: 10.1152/ajprenal.00246.2009 PMID: 19587143
    • (2009) Am J Physiol Renal Physiol , vol.297 , pp. F577-F582
    • Axelsson, J.1    Mahmutovic, I.2    Rippe, A.3    Rippe, B.4
  • 22
    • 1642533459 scopus 로고    scopus 로고
    • Plasma mitochondrial DNA concentrations after trauma
    • PMID: 14709653
    • Lam NY, Rainer TH, Chiu RW, Joynt GM, Lo YM. Plasma mitochondrial DNA concentrations after trauma. Clin Chem. 2004; 50: 213-216. PMID: 14709653
    • (2004) Clin Chem , vol.50 , pp. 213-216
    • Lam, N.Y.1    Rainer, T.H.2    Chiu, R.W.3    Joynt, G.M.4    Lo, Y.M.5
  • 23
    • 84884502884 scopus 로고    scopus 로고
    • Elevated levels of plasma mitochondrial DNA DAMPs are linked to clinical outcome in severely injured human subjects
    • PMID: 23979273
    • Simmons JD, Lee Y-L, Mulekar S, Kuck JL, Brevard SB, Gonzalez RP, et al. Elevated levels of plasma mitochondrial DNA DAMPs are linked to clinical outcome in severely injured human subjects. Ann Surg. 2013; 258: 591-598. doi: 10.1097/SLA.0b013e3182a4ea46 PMID: 23979273
    • (2013) Ann Surg , vol.258 , pp. 591-598
    • Simmons, J.D.1    Lee, Y.-L.2    Mulekar, S.3    Kuck, J.L.4    Brevard, S.B.5    Gonzalez, R.P.6
  • 24
    • 84882602985 scopus 로고    scopus 로고
    • The plasma mitochondrial DNA is an independent predictor for post-traumatic systemic inflammatory response syndrome
    • PMID: 23977360
    • Gu X, Yao Y, Wu G, Lv T, Luo L, Song Y. The plasma mitochondrial DNA is an independent predictor for post-traumatic systemic inflammatory response syndrome. PLoS One. 2013; 8:e72834. doi: 10.1371/journal.pone.0072834 PMID: 23977360
    • (2013) PLoS One , vol.8
    • Gu, X.1    Yao, Y.2    Wu, G.3    Lv, T.4    Luo, L.5    Song, Y.6
  • 25
    • 50649092885 scopus 로고    scopus 로고
    • Plasma nuclear DNA and mitochondrial DNA as prognostic markers in corrosive injury patients
    • PMID: 18769068
    • Chou CC, Fang HY, Chen YL, Wu CY, Siao FY, Chou MJ. Plasma nuclear DNA and mitochondrial DNA as prognostic markers in corrosive injury patients. Dig Surg. 2008; 25:300-304. doi: 10.1159/ 000152846 PMID: 18769068
    • (2008) Dig Surg , vol.25 , pp. 300-304
    • Chou, C.C.1    Fang, H.Y.2    Chen, Y.L.3    Wu, C.Y.4    Siao, F.Y.5    Chou, M.J.6
  • 26
    • 84887402250 scopus 로고    scopus 로고
    • Plasma mitochondrial DNA levels in patients with trauma and severe sepsis: Time course and the association with clinical status
    • PMID: 23787023
    • Yamanouchi S, Kudo D, Yamada M, Miyagawa N, Furukawa H, Kushimoto S. Plasma mitochondrial DNA levels in patients with trauma and severe sepsis: time course and the association with clinical status. J Crit Care. 2013; 28:1027-1031. doi: 10.1016/j.jcrc.2013.05.006 PMID: 23787023
    • (2013) J Crit Care , vol.28 , pp. 1027-1031
    • Yamanouchi, S.1    Kudo, D.2    Yamada, M.3    Miyagawa, N.4    Furukawa, H.5    Kushimoto, S.6
  • 27
    • 77953901974 scopus 로고    scopus 로고
    • Mitochondrial DNA is released by shock and activates neutrophils via p38 map kinase
    • PMID: 19997055
    • Zhang Q, Itagaki K, Hauser C J. Mitochondrial DNA is released by shock and activates neutrophils via p38 map kinase. Shock. 2010; 34: 55-59. doi: 10.1097/SHK.0b013e3181cd8c08 PMID: 19997055
    • (2010) Shock , vol.34 , pp. 55-59
    • Zhang, Q.1    Itagaki, K.2    Hauser, C.J.3
  • 28
    • 84890493298 scopus 로고    scopus 로고
    • Role of circulating cell-free DNA levels in patients with severe preeclampsia and HELLP syndrome
    • PMID: 24103646
    • Miranda ML, Macher HC, Muñoz-Hernández R, Vallejo-Vaz A, Moreno-Luna R, Villar J. Role of circulating cell-free DNA levels in patients with severe preeclampsia and HELLP syndrome. Am J Hypertens. 2013; 26:1377-1380. doi: 10.1093/ajh/hpt187 PMID: 24103646
    • (2013) Am J Hypertens , vol.26 , pp. 1377-1380
    • Miranda, M.L.1    Macher, H.C.2    Muñoz-Hernández, R.3    Vallejo-Vaz, A.4    Moreno-Luna, R.5    Villar, J.6
  • 29
    • 84864008391 scopus 로고    scopus 로고
    • Toll-like receptor 9 activation: A novel mechanism linking placenta-derived mitochondrial DNA and vascular dysfunction in pre-eclampsia
    • PMID: 22671429
    • Goulopoulou S, Matsumoto T, Bomfim GF, Webb RC. Toll-like receptor 9 activation: a novel mechanism linking placenta-derived mitochondrial DNA and vascular dysfunction in pre-eclampsia. Clin Sci (Lond). 2012; 123:429-435. doi: 10.1042/CS20120130 PMID: 22671429
    • (2012) Clin Sci (Lond) , vol.123 , pp. 429-435
    • Goulopoulou, S.1    Matsumoto, T.2    Bomfim, G.F.3    Webb, R.C.4
  • 30
    • 0024269811 scopus 로고
    • Rapid isolation method of animal mitochondrial DNA by the alkaline lysis procedure
    • PMID: 3242492
    • Tamura K, Aotsuka T. Rapid isolation method of animal mitochondrial DNA by the alkaline lysis procedure. Biochem Genet. 1988; 26: 815-819. PMID: 3242492
    • (1988) Biochem Genet , vol.26 , pp. 815-819
    • Tamura, K.1    Aotsuka, T.2
  • 31
    • 77649180087 scopus 로고    scopus 로고
    • Isolation of intact nuclei of high purity from mouse liver
    • PMID: 19925772
    • Nagata T, Redman RS, Lakshman R. Isolation of intact nuclei of high purity from mouse liver. Anal Biochem. 2010; 398: 178-184. doi: 10.1016/j.ab.2009.11.017 PMID: 19925772
    • (2010) Anal Biochem , vol.398 , pp. 178-184
    • Nagata, T.1    Redman, R.S.2    Lakshman, R.3
  • 32
    • 0036189998 scopus 로고    scopus 로고
    • A conditionally immortalized human podocyte cell line demonstrating nephrin and podocin expression
    • PMID: 11856766
    • Saleem M, O'Hare M, Reiser J, Coward R, Inward C, Farren T, et al. A conditionally immortalized human podocyte cell line demonstrating nephrin and podocin expression. J Am Soc Nephrol. 2002; 13:630-638. PMID: 11856766
    • (2002) J Am Soc Nephrol , vol.13 , pp. 630-638
    • Saleem, M.1    O'Hare, M.2    Reiser, J.3    Coward, R.4    Inward, C.5    Farren, T.6
  • 33
    • 84884633364 scopus 로고    scopus 로고
    • Smad2-dependent downregulation of miR-30 is required for TGF-β-induced apoptosis in podocytes
    • PMID: 24086574
    • Shi S, Yu L, Zhang T, Qi H, Xavier S, Ju W, et al. Smad2-dependent downregulation of miR-30 is required for TGF-β-induced apoptosis in podocytes. PLoS One. 2013; 8:e75572. doi: 10.1371/journal.pone.0075572 PMID: 24086574
    • (2013) PLoS One , vol.8
    • Shi, S.1    Yu, L.2    Zhang, T.3    Qi, H.4    Xavier, S.5    Ju, W.6
  • 34
    • 55749112141 scopus 로고    scopus 로고
    • Podocyte-selective deletion of dicer induces proteinuria and glomerulosclerosis
    • PMID: 18776119
    • Shi S, Yu L, Chiu C, Sun Y, Chen J, Khitrov G, et al. Podocyte-selective deletion of dicer induces proteinuria and glomerulosclerosis. J Am Soc Nephrol. 2008; 19:2159-2169. doi: 10.1681/ASN.2008030312 PMID: 18776119
    • (2008) J Am Soc Nephrol , vol.19 , pp. 2159-2169
    • Shi, S.1    Yu, L.2    Chiu, C.3    Sun, Y.4    Chen, J.5    Khitrov, G.6
  • 35
    • 0028354234 scopus 로고
    • Pervasive CpG suppression in animal mitochondrial genomes
    • PMID: 8170990
    • Cardon LR, Burge C, Clayton DA, Karlin S. Pervasive CpG suppression in animal mitochondrial genomes. Proc Natl Acad Sci U S A. 1994; 91: 3799-3803. PMID: 8170990
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 3799-3803
    • Cardon, L.R.1    Burge, C.2    Clayton, D.A.3    Karlin, S.4
  • 36
    • 0014213508 scopus 로고
    • Mitochondrial DNA. I. Preparation and properties of mitochondrial DNA from chick liver
    • PMID: 4295781
    • Borst P, Ruttenberg JC, Kroon AM. Mitochondrial DNA. I. Preparation and properties of mitochondrial DNA from chick liver. Biochim Biophys Acta. 1967; 149:140-155. PMID: 4295781
    • (1967) Biochim Biophys Acta , vol.149 , pp. 140-155
    • Borst, P.1    Ruttenberg, J.C.2    Kroon, A.M.3
  • 37
    • 84879599357 scopus 로고    scopus 로고
    • Identification of novel oligonucleotides from mitochondrial DNA that spontaneously induce plasmacytoid dendritic cell activation
    • PMID: 23610148
    • Ries M, Schuster P, Thomann S, Donhauser N, Vollmer J, Schmidt B. Identification of novel oligonucleotides from mitochondrial DNA that spontaneously induce plasmacytoid dendritic cell activation. J Leukoc Biol. 2013; 94: 123-135. doi: 10.1189/jlb.0612278 PMID: 23610148
    • (2013) J Leukoc Biol , vol.94 , pp. 123-135
    • Ries, M.1    Schuster, P.2    Thomann, S.3    Donhauser, N.4    Vollmer, J.5    Schmidt, B.6
  • 38
    • 66449102219 scopus 로고    scopus 로고
    • Monocyte activation by necrotic cells is promoted by mitochondrial proteins and formyl peptide receptors
    • PMID: 19384205
    • Crouser ED, Shao G, Julian MW, Macre JE, Shadel GS, Tridandapani S, et al. Monocyte activation by necrotic cells is promoted by mitochondrial proteins and formyl peptide receptors. Crit Care Med. 2009; 37: 2000-2009. doi: 10.1097/CCM.0b013e3181a001ae PMID: 19384205
    • (2009) Crit Care Med , vol.37 , pp. 2000-2009
    • Crouser, E.D.1    Shao, G.2    Julian, M.W.3    Macre, J.E.4    Shadel, G.S.5    Tridandapani, S.6
  • 39
    • 79952749156 scopus 로고    scopus 로고
    • DNA methyltransferase 1, cytosine methylation, and cytosine hydroxymethylation in mammalian mitochondria
    • PMID: 21321201
    • Shock LS, Thakkar PV, Peterson EJ, Moran RG, Taylor SM. DNA methyltransferase 1, cytosine methylation, and cytosine hydroxymethylation in mammalian mitochondria. Proc Natl Acad Sci U S A. 2011; 108: 3630-3635. doi: 10.1073/pnas.1012311108 PMID: 21321201
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 3630-3635
    • Shock, L.S.1    Thakkar, P.V.2    Peterson, E.J.3    Moran, R.G.4    Taylor, S.M.5
  • 41
    • 84861467922 scopus 로고    scopus 로고
    • Mitochondrial transcription factor A is a proinflammatory mediator in hemorrhagic shock
    • PMID: 22469910
    • Chaung WW, Wu R, Ji Y, Dong W, Wang P. Mitochondrial transcription factor A is a proinflammatory mediator in hemorrhagic shock. Int J Mol Med. 2012; 30:199-203. doi: 10.3892/ijmm.2012.959 PMID: 22469910
    • (2012) Int J Mol Med , vol.30 , pp. 199-203
    • Chaung, W.W.1    Wu, R.2    Ji, Y.3    Dong, W.4    Wang, P.5
  • 42
    • 84900020940 scopus 로고    scopus 로고
    • Mitochondrial transcription factor A (Tfam) is a pro-inflammatory extracellular signaling molecule recognized by brain microglia
    • PMID: 24769106
    • Little JP, Simtchouk S, Schindler SM, Villanueva EB, Gill NE, Walker DG, et al. Mitochondrial transcription factor A (Tfam) is a pro-inflammatory extracellular signaling molecule recognized by brain microglia. Mol Cell Neurosci. 2014; 60:88-96. doi: 10.1016/j.mcn.2014.04.003 PMID: 24769106
    • (2014) Mol Cell Neurosci , vol.60 , pp. 88-96
    • Little, J.P.1    Simtchouk, S.2    Schindler, S.M.3    Villanueva, E.B.4    Gill, N.E.5    Walker, D.G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.