4-hydroxynonenal causes impairment of human subcutaneous adipogenesis and induction of adipocyte insulin resistance

Free Radical Biology and Medicine

Volumn 104, Issue , 2017, Pages 129-137

  Elrayess, Mohamed A ^a   Almuraikhy, Shamma ^a,b   Kafienah, Wael ^b   Al Menhali, Afnan ^a   Al Khelaifi, Fatima ^a   Bashah, Moataz ^c   Zarkovic, Kamelija ^d   Zarkovic, Neven ^e   Waeg, Georg ^f   Alsayrafi, Mohammed ^a   Jaganjac, Morana ^a  

^a Anti Doping Lab Qatar Sports City ^*  (Qatar)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c HAMAD MEDICAL CORPORATION   (Qatar)

^d KBC Zagreb   (Croatia)

^e RUDER BO KOVI INSTITUTE   (Croatia)

^f UNIVERSITY OF GRAZ   (Austria)

Author keywords

4 hydroxynonenal; Adipogenesis; Insulin resistance; Insulin sensitivity; Obesity preadipocytes; Redox homeostasis; Subcutaneous fat

Indexed keywords

4 HYDROXYNONENAL; GLYCOGEN SYNTHASE KINASE 3ALPHA; GLYCOGEN SYNTHASE KINASE 3BETA; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; PROTEIN BAD; REACTIVE OXYGEN METABOLITE; 4-HYDROXY-2-NONENAL; ALDEHYDE;

ADIPOGENESIS; ARTICLE; BLOOD VESSEL; CELL DIFFERENTIATION; CELL GROWTH; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME SYNTHESIS; FEMALE; GROWTH INHIBITION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INSULIN RESISTANCE; INSULIN SENSITIVITY; LONG TERM EXPOSURE; MORBID OBESITY; OBESITY; OXIDATIVE STRESS; PHENOTYPE; PREMENOPAUSE; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN DEPHOSPHORYLATION; SUBCUTANEOUS FAT; WEIGHT REDUCTION; ADIPOCYTE; ADULT; ANIMAL; CELL PROLIFERATION; DRUG EFFECTS; GENETICS; METABOLISM; MOUSE; PATHOLOGY;

ADIPOCYTES; ADIPOGENESIS; ADULT; ALDEHYDES; ANIMALS; BLOOD VESSELS; CELL PROLIFERATION; FEMALE; HUMANS; INSULIN RESISTANCE; MICE; OBESITY; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 85009281031     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2017.01.015     Document Type: Article

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