Amino acids in hemagglutinin antigenic site B determine antigenic and receptor binding differences between A(H3N2)v and ancestral seasonal H3N2 influenza viruses.

Journal of Virology

Volumn 91, Issue 2, 2017, Pages

  Wang, Xiaoquan ^a   Ilyushina, Natalia A ^a   Lugovtsev, Vladimir Y ^a   Bovin, Nicolai V ^b   Couzens, Laura K ^a   Gao, Jin ^a   Donnelly, Raymond P ^a   Eichelberger, Maryna C ^a   Wan, Hongquan ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^b SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

Author keywords

A(H3N2)v; Amino acid; Antigenic phenotype; Hemagglutinin; Influenza virus

Indexed keywords

VIRUS HEMAGGLUTININ; AMINO ACID; EPITOPE; INFLUENZA VIRUS HEMAGGLUTININ; VIRUS ANTIBODY; VIRUS ANTIGEN; VIRUS RECEPTOR;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGENIC SITE B; ANTIGENICITY; ARTICLE; CONTROLLED STUDY; EMBRYO; FERRET; HEMAGGLUTINATION INHIBITION; HUMAN; HUMAN CELL; INFLUENZA A (H3N2); INFLUENZA A VIRUS (A/BEIJING/32/1992(H3N2)); INFLUENZA A VIRUS (A/MINNESOTA/11/2010(H3N2)); INFLUENZA A VIRUS (H3N2); MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RECEPTOR BINDING; RISK ASSESSMENT; VIRUS MUTATION; VIRUS PATHOGENESIS; VIRUS STRAIN; AMINO ACID SEQUENCE; ANIMAL; ANTIGENIC VARIATION; GENETICS; IMMUNOLOGY; METABOLISM; MUSTELA PUTORIUS FURO; MUTATION; ORTHOMYXOVIRUS INFECTION; PHYSIOLOGY; VIROLOGY; VIRUS ATTACHMENT;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO ACIDS; ANIMALS; ANTIBODIES, VIRAL; ANTIGENIC VARIATION; ANTIGENS, VIRAL; EPITOPES; FERRETS; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; HUMANS; INFLUENZA A VIRUS, H3N2 SUBTYPE; MUTATION; ORTHOMYXOVIRIDAE INFECTIONS; PHENOTYPE; RECEPTORS, VIRUS; VIRUS ATTACHMENT;

EID: 85008676961     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01512-16     Document Type: Article

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