Exogenous Hydrogen Sulfide Attenuates High Glucose-Induced Cardiotoxicity by Inhibiting NLRP3 Inflammasome Activation by Suppressing TLR4/NF-κB Pathway in H9c2 Cells

Cellular Physiology and Biochemistry

Volumn 40, Issue 6, 2016, Pages 1578-1590

  Huang, Zena ^a   Zhuang, Xiaodong ^a   Xie, Chuli ^b   Hu, Xun ^a   Dong, Xiaobian ^a   Guo, Yue ^a   Li, Shaofen ^c   Liao, Xinxue ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c Liwan District Oral Hospital   (China)

Author keywords

Cardiac cell; Hydrogen sulphide; Hyperglycemia; NLRP3 inflammasome; TLR4

Indexed keywords

ASC PROTEIN; BINDING PROTEIN; CASPASE 3; CRYOPYRIN; CYSTEINE PROTEINASE; GLUCOSE; HYDROGEN SULFIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; PRO CASPASE 1; REACTIVE OXYGEN METABOLITE; SODIUM HYDROSULFIDE; SULFUR DERIVATIVE; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG; NLRP3 PROTEIN, RAT;

ANIMAL CELL; APOPTOSIS; ARTICLE; ATTENUATION; CARDIAC MUSCLE CELL; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; EMBRYO; GENE REPRESSION; GROWTH INHIBITION; HEART PROTECTION; IN VITRO STUDY; INFLAMMATION; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANIMAL; BIOLOGICAL MODEL; CARDIOTOXICITY; CELL LINE; CELL PROTECTION; DRUG EFFECTS; GENE SILENCING; METABOLISM; PATHOLOGY; RAT;

ANIMALS; APOPTOSIS; CARDIOTOXICITY; CELL LINE; CYTOPROTECTION; GENE SILENCING; GLUCOSE; HYDROGEN SULFIDE; INFLAMMASOMES; INFLAMMATION; MODELS, BIOLOGICAL; MYOCYTES, CARDIAC; NF-KAPPA B; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; RATS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

EID: 85008645137     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000453208     Document Type: Article

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