Inherited CD70 deficiency in humans reveals a critical role for the CD70-CD27 pathway in immunity to Epstein-Barr virus infection

Journal of Experimental Medicine

Volumn 214, Issue 1, 2017, Pages 73-89

  Izawa, Kazushi ^a,i   Martin, Emmanuel ^a   Soudais, Claire ^a,c   Bruneau, Julie ^c,d   Boutboul, David ^a   Rodriguez, Rémy ^a,c   Lenoir, Christelle ^a   Hislop, Andrew D ^e   Besson, Caroline ^f   Touzot, Fabien ^c,d   Picard, Capucine ^b,c,d   Callebaut, Isabelle ^g   de Villartay, Jean Pierre ^a,c   Moshous, Despina ^a,c,d   Fischer, Alain ^a,c,d,h   Latour, Sylvain ^a,c  

^a INSERM   (France)

^b IMAGINE INSTITUTE   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d HÔPITAL NECKER ENFANTS MALADES   (France)

^e UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^f BICÊTRE HOSPITAL   (France)

^g CNRS   (France)

^h Centre de Recherche Interdisciplinaire en Biologie   (France)

ⁱ KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; B CELL ACTIVATING FACTOR RECEPTOR; CD137 LIGAND; CD27 ANTIGEN; CD70 ANTIGEN; HLA A1 ANTIGEN; HLA A2 ANTIGEN; HLA A3 ANTIGEN; IMMUNOGLOBULIN; OX40 LIGAND; TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR; CD70 PROTEIN, HUMAN; LYMPHOCYTE ANTIGEN RECEPTOR; STOP CODON;

ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; ARTICLE; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CASE REPORT; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CELL PROLIFERATION; CELLULAR IMMUNITY; CHILD; EGYPTIAN; EPSTEIN BARR VIRUS INFECTION; GENETIC VARIATION; HEK293 CELL LINE; HEPATOSPLENOMEGALY; HODGKIN DISEASE; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; IMMUNOSURVEILLANCE; LYMPHADENOPATHY; LYMPHOPROLIFERATIVE DISEASE; MALE; MEMORY CELL; NATURAL KILLER T CELL; NONSENSE MUTATION; PERIPHERAL BLOOD MONONUCLEAR CELL; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN EXPRESSION; RECURRENT FEVER; SCHOOL CHILD; T LYMPHOCYTE; UPREGULATION; VIRUS LOAD; WHOLE EXOME SEQUENCING; B LYMPHOCYTE; DEFICIENCY; GENETICS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; PHYSIOLOGY; SIGNAL TRANSDUCTION; STOP CODON;

ANTIGENS, CD27; ANTIGENS, CD70; B-LYMPHOCYTES; CHILD; CODON, NONSENSE; EPSTEIN-BARR VIRUS INFECTIONS; HUMANS; LYMPHOCYTE ACTIVATION; MALE; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 85008474195     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20160784     Document Type: Article

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