CD70-CD27 interactions provide survival and proliferative signals that regulate T cell receptor-driven activation of human γδ peripheral blood lymphocytes

European Journal of Immunology

Volumn 41, Issue 1, 2011, Pages 195-201

  deBarros, Ana ^a,b   Chaves Ferreira, Miguel ^a,c   D'Orey, Francisco ^a   Ribot, Julie C ^a,b   Silva Santos, Bruno ^a,b  

^a INSTITUTO DE MEDICINA MOLECULAR   (Portugal)

^b INSTITUTO GULBENKIAN DE CIÊNCIA   (Portugal)

^c INSERM   (France)

Author keywords

CD27; CD70; Costimulation; Gd T cells

Indexed keywords

BCL2 RELATED PROTEIN A1; CD27 ANTIGEN; CD70 ANTIGEN; CYCLIN D2; T LYMPHOCYTE RECEPTOR;

ANTIGEN EXPRESSION; ARTICLE; B CELL LYMPHOMA; CELL ACTIVATION; CELL EXPANSION; CELL PROLIFERATION; CELL SURVIVAL; CHEMICAL INTERACTION; CONTROLLED STUDY; CYTOKINE RELEASE; GAMMADELTA PERIPHERAL LYMPHOCYTE; HUMAN; HUMAN CELL; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; TH1 CELL;

ANTIGENS, CD27; ANTIGENS, CD70; CALCIUM; CELL COMMUNICATION; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CYCLIN D2; CYTOKINES; HUMANS; INTERLEUKIN-2; LYMPHOCYTE ACTIVATION; ORGANOPHOSPHORUS COMPOUNDS; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; T-LYMPHOCYTE SUBSETS; TH1 CELLS; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 78650334358     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201040905     Document Type: Article

References (25)

1. Girardi, M., Oppenheim, D. E., Steele, C. R., Lewis, J. M., Glusac, E., Filler, R., Hobby, P. et al., Regulation of cutaneous malignancy by gammadelta T cells. Science 2001. 294: 605-609.
2. Kabelitz, D., Wesch, D. and He, W., Perspectives of gammadelta T cells in tumor immunology. Cancer Res. 2007. 67: 5-8.
3. Kong, Y., Cao, W., Xi, X., Ma, C., Cui, L. and He, W., The NKG2D ligand ULBP4 binds to TCRgamma9/delta2 and induces cytotoxicity to tumor cells through both TCRgammadelta and NKG2D. Blood 2009. 114: 310-317.
4. Lanca, T., Correia, D. V., Moita, C. F., Raquel, H., Neves-Costa, A., Ferreira, C., Ramalho, J. S. et al., The MHC class Ib protein ULBP1 is a nonredundant determinant of leukemia/lymphoma susceptibility to gammadelta T-cell cytotoxicity. Blood 2010. 115: 2407-2411.
5. Dieli, F., Vermijlen, D., Fulfaro, F., Caccamo, N., Meraviglia, S., Cicero, G., Roberts, A. et al., Targeting human gammadelta T cells with zoledronate and interleukin-2 for immunotherapy of hormone-refractory prostate cancer. Cancer Res. 2007. 67: 7450-7457.
6. Wilhelm, M., Kunzmann, V., Eckstein, S., Reimer, P., Weissinger, F., Ruediger, T. and Tony, H. P., Gammadelta T cells for immune therapy of patients with lymphoid malignancies. Blood 2003. 102: 200-206.
7. Dieli, F., Troye-Blomberg, M., Farouk, S. E., Sireci, G. and Salerno, A., Biology of gammadelta T cells in tuberculosis and malaria. Curr. Mol. Med. 2001. 1: 437-446.
8. D'Ombrain, M. C., Robinson, L. J., Stanisic, D. I., Taraika, J., Bernard, N., Michon, P., Mueller, I. and Schofield, L., Association of early interferon-gamma production with immunity to clinical malaria: a longitudinal study among Papua New Guinean children. Clin. Infect. Dis. 2008. 47: 1380-1387.
9. Morita, C. T., Jin, C., Sarikonda, G. and Wang, H., Nonpeptide antigens, presentation mechanisms, and immunological memory of human Vgamma2Vdelta2 T cells: discriminating friend from foe through the recognition of prenyl pyrophosphate antigens. Immunol. Rev. 2007. 215: 59-76.
10. Nedellec, S., Bonneville, M. and Scotet, E., Human Vgamma9Vdelta2 T cells: from signals to functions. Semin. Immunol. 2010. 22: 199-206.
11. Chen, Y., Shao, L., Ali, Z., Cai, J. and Chen, Z. W., NSOM/QD-based nanoscale immunofluorescence imaging of antigen-specific T-cell receptor responses during an in vivo clonal Vgamma2Vdelta2 T-cell expansion. Blood 2008. 111: 4220-4232.
12. Correia, D. V., d'Orey, F., Cardoso, B. A., Lanca, T., Grosso, A. R., deBarros, A., Martins, L. R. et al., Highly active microbial phosphoantigen induces rapid yet sustained MEK/Erk- and PI-3K/Akt-mediated signal transduction in anti-tumor human gammadelta T cells. PLoS One 2009. 4: e5657.
13. Acuto, O., Mise-Omata, S., Mangino, G. and Michel, F., Molecular modifiers of T cell antigen receptor triggering threshold: the mechanism of CD28 costimulatory receptor. Immunol. Rev. 2003. 192: 21-31.
14. Borst, J., Hendriks, J. and Xiao, Y., CD27 and CD70 in T cell and B cell activation. Curr. Opin. Immunol. 2005. 17: 275-281.
15. Dieli, F., Poccia, F., Lipp, M., Sireci, G., Caccamo, N., Di Sano, C. and Salerno, A., Differentiation of effector/memory Vdelta2 T cells and migratory routes in lymph nodes or inflammatory sites. J. Exp. Med. 2003. 198: 391-397.
16. Ribot, J. C., deBarros, A., Pang, D. J., Neves, J. F., Peperzak, V., Roberts, S. J., Girardi, M. et al., CD27 is a thymic determinant of the balance between interferon-gamma- and interleukin 17-producing gammadelta T cell subsets. Nat. Immunol. 2009. 10: 427-436.
17. Brandes, M., Willimann, K., Bioley, G., Levy, N., Eberl, M., Luo, M., Tampe, R. et al., Cross-presenting human gammadelta T cells induce robust CD8+ alphabeta T cell responses. Proc. Natl. Acad. Sci. USA 2009. 106: 2307-2312.
18. Brandes, M., Willimann, K. and Moser, B., Professional antigen-presentation function by human gammadelta T cells. Science 2005. 309: 264-268.
19. Brandes, M., Willimann, K., Lang, A. B., Nam, K. H., Jin, C., Brenner, M. B., Morita, C. T. and Moser, B., Flexible migration program regulates gamma delta T-cell involvement in humoral immunity. Blood 2003. 102: 3693-3701.
20. Glouchkova, L., Ackermann, B., Zibert, A., Meisel, R., Siepermann, M., Janka-Schaub, G. E., Goebel, U. et al., The CD70/CD27 pathway is critical for stimulation of an effective cytotoxic T cell response against B cell precursor acute lymphoblastic leukemia. J. Immunol. 2009. 182: 718-725.
21. Rowley, T. F. and Al-Shamkhani, A., Stimulation by soluble CD70 promotes strong primary and secondary CD8+ cytotoxic T cell responses in vivo. J. Immunol. 2004. 172: 6039-6046.
22. Soares, H., Waechter, H., Glaichenhaus, N., Mougneau, E., Yagita, H., Mizenina, O., Dudziak, D. et al., A subset of dendritic cells induces CD4+ T cells to produce IFN-gamma by an IL-12-independent but CD70-dependent mechanism in vivo. J. Exp. Med. 2007. 204: 1095-1106.
23. French, R. R., Taraban, V. Y., Crowther, G. R., Rowley, T. F., Gray, J. C., Johnson, P. W., Tutt, A. L. et al., Eradication of lymphoma by CD8 T cells following anti-CD40 monoclonal antibody therapy is critically dependent on CD27 costimulation. Blood 2007. 109: 4810-4815.
24. Keller, A. M., Schildknecht, A., Xiao, Y., van den Broek, M. and Borst, J., Expression of costimulatory ligand CD70 on steady-state dendritic cells breaks CD8+ T cell tolerance and permits effective immunity. Immunity 2008. 29: 934-946.
25. Keller, A. M., Xiao, Y., Peperzak, V., Naik, S. H. and Borst, J., Costimulatory ligand CD70 allows induction of CD8+ T-cell immunity by immature dendritic cells in a vaccination setting. Blood 2009. 113: 5167-5175.