Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD

Journal of Experimental Medicine

Volumn 214, Issue 1, 2017, Pages 143-163

  Baarsma, Hoeke A ^a   Skronska Wasek, Wioletta ^a   Mutze, Kathrin ^a   Ciolek, Florian ^a   Wagner, Darcy E ^a   John Schuster, Gerrit ^a   Heinzelmann, Katharina ^a   Günther, Andreas ^b   Bracke, Ken R ^c   Dagouassat, Maylis ^d   Boczkowski, Jorge ^d   Brusselle, Guy G ^c   Smits, Ron ^e   Eickelberg, Oliver ^a   Yildirim, Ali Ö ^a   Königshoff, Melanie ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b JUSTUS LIEBIG UNIVERSITY GIESSEN   (Germany)

^c GHENT UNIVERSITY HOSPITAL   (Belgium)

^d INSERM U955   (France)

^e ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CIGARETTE SMOKE; ELASTASE; TRANSFORMING GROWTH FACTOR BETA; WNT5A PROTEIN; WNT5A PROTEIN, HUMAN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL TRANSDIFFERENTIATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE EXACERBATION; ELASTASE-INDUCED EMPHYSEMA; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; INFANT; LUNG ALVEOLUS EPITHELIUM CELL; LUNG FIBROBLAST; LUNG FUNCTION; LUNG INJURY; LUNG SURGERY; MIDDLE AGED; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; SENESCENCE; WOUND HEALING; ADVERSE EFFECTS; ANIMAL; C57BL MOUSE; CELL CULTURE; EMPHYSEMA; LUNG; PATHOPHYSIOLOGY; PHYSIOLOGY; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SMOKING; WNT SIGNALING PATHWAY;

ANIMALS; BETA CATENIN; CELLS, CULTURED; EMPHYSEMA; FEMALE; LUNG; MICE; MICE, INBRED C57BL; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SMOKING; WNT SIGNALING PATHWAY; WNT-5A PROTEIN;

EID: 85008468138     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20160675     Document Type: Article

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