-
1
-
-
84867814699
-
Chimeric antigen receptors for T-cell based therapy
-
Cheadle EJ, Sheard V, Hombach AA et al. Chimeric antigen receptors for T-cell based therapy. Methods Mol Biol 2012; 907: 645-666.
-
(2012)
Methods Mol Biol
, vol.907
, pp. 645-666
-
-
Cheadle, E.J.1
Sheard, V.2
Hombach, A.A.3
-
2
-
-
84858758766
-
Adoptive immunotherapy for cancer: Harnessing the T cell response
-
Restifo NP, Dudley ME, Rosenberg SA. Adoptive immunotherapy for cancer: harnessing the T cell response. Nat Rev Immunol 2012; 12: 269-281.
-
(2012)
Nat Rev Immunol
, vol.12
, pp. 269-281
-
-
Restifo, N.P.1
Dudley, M.E.2
Rosenberg, S.A.3
-
3
-
-
84921487573
-
Designing chimeric antigen receptors to effectively and safely target tumors
-
Jensen MC, Riddell SR. Designing chimeric antigen receptors to effectively and safely target tumors. Curr Opin Immunol 2015; 33: 9-15.
-
(2015)
Curr Opin Immunol
, vol.33
, pp. 9-15
-
-
Jensen, M.C.1
Riddell, S.R.2
-
4
-
-
79958023047
-
Chimeric antigen receptor (CAR)-engineered lymphocytes for cancer therapy
-
Ramos CA, Dotti G. Chimeric antigen receptor (CAR)-engineered lymphocytes for cancer therapy. Expert Opin Biol Ther 2011; 11: 855-873.
-
(2011)
Expert Opin Biol Ther
, vol.11
, pp. 855-873
-
-
Ramos, C.A.1
Dotti, G.2
-
5
-
-
84876325876
-
Chimeric Antigen receptor-modified T cells for acute lymphoid leukemia
-
Grupp SA, Kalos M, Barrett D et al. Chimeric Antigen receptor-modified T cells for acute lymphoid leukemia. New Engl J Med 2013; 368: 1509-1518.
-
(2013)
New Engl J Med
, vol.368
, pp. 1509-1518
-
-
Grupp, S.A.1
Kalos, M.2
Barrett, D.3
-
6
-
-
84908073316
-
chimeric antigen receptor T cells for sustained remissions in leukemia
-
Maude SL, Frey N, Shaw PA et al. chimeric antigen receptor T cells for sustained remissions in leukemia. New Engl J Med 2014; 371: 1507-1517.
-
(2014)
New Engl J Med
, vol.371
, pp. 1507-1517
-
-
Maude, S.L.1
Frey, N.2
Shaw, P.A.3
-
7
-
-
80051720194
-
Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia
-
Porter DL, Levine BL, Kalos M, Bagg A, June CH. Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia. New Engl J Med 2011; 365: 725-733.
-
(2011)
New Engl J Med
, vol.365
, pp. 725-733
-
-
Porter, D.L.1
Levine, B.L.2
Kalos, M.3
Bagg, A.4
June, C.H.5
-
8
-
-
80455179612
-
Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias
-
Brentjens RJ, Riviere I, Park JH et al. Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias. Blood 2011; 118: 4817-4828.
-
(2011)
Blood
, vol.118
, pp. 4817-4828
-
-
Brentjens, R.J.1
Riviere, I.2
Park, J.H.3
-
9
-
-
84863337890
-
B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells
-
Kochenderfer JN, Dudley ME, Feldman SA et al. B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells. Blood 2012; 119: 2709-2720.
-
(2012)
Blood
, vol.119
, pp. 2709-2720
-
-
Kochenderfer, J.N.1
Dudley, M.E.2
Feldman, S.A.3
-
10
-
-
0030823184
-
Replicative senescence of T cells: Does the Hayflick Limit lead to immune exhaustion?
-
Effros RB, Pawelec G. Replicative senescence of T cells: does the Hayflick Limit lead to immune exhaustion? Immunol Today 1997; 18: 450-454.
-
(1997)
Immunol Today
, vol.18
, pp. 450-454
-
-
Effros, R.B.1
Pawelec, G.2
-
11
-
-
27744450650
-
Telomere length of transferred lymphocytes correlates with in vivo persistence and tumor regression in melanoma patients receiving cell transfer therapy
-
Zhou J, Shen X, Huang J et al. Telomere length of transferred lymphocytes correlates with in vivo persistence and tumor regression in melanoma patients receiving cell transfer therapy. J Immunol 2005; 175: 7046-7052.
-
(2005)
J Immunol
, vol.175
, pp. 7046-7052
-
-
Zhou, J.1
Shen, X.2
Huang, J.3
-
12
-
-
70350726110
-
Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo
-
Milone MC, Fish JD, Carpenito C et al. Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo. Mol Ther 2009; 17: 1453-1464.
-
(2009)
Mol Ther
, vol.17
, pp. 1453-1464
-
-
Milone, M.C.1
Fish, J.D.2
Carpenito, C.3
-
13
-
-
10344261422
-
Cutting edge: Persistence of transferred lymphocyte clonotypes correlates with cancer regression in patients receiving cell transfer therapy
-
Robbins PF, Dudley ME, Wunderlich J et al. Cutting edge: persistence of transferred lymphocyte clonotypes correlates with cancer regression in patients receiving cell transfer therapy. J Immunol 2004; 173: 7125-7130.
-
(2004)
J Immunol
, vol.173
, pp. 7125-7130
-
-
Robbins, P.F.1
Dudley, M.E.2
Wunderlich, J.3
-
14
-
-
33846028221
-
Persistence of tumor infiltrating lymphocytes in adoptive immunotherapy correlates with telomere length
-
Shen X, Zhou J, Hathcock KS et al. Persistence of tumor infiltrating lymphocytes in adoptive immunotherapy correlates with telomere length. J Immunother 2007; 30: 123-129.
-
(2007)
J Immunother
, vol.30
, pp. 123-129
-
-
Shen, X.1
Zhou, J.2
Hathcock, K.S.3
-
16
-
-
0034326634
-
Ectopic human telomerase catalytic subunit expression maintains telomere length but is not sufficient for CD8+ T lymphocyte immortalization
-
Migliaccio M, Amacker M, Just T et al. Ectopic human telomerase catalytic subunit expression maintains telomere length but is not sufficient for CD8+ T lymphocyte immortalization. J Immunol 2000; 165: 4978-4984.
-
(2000)
J Immunol
, vol.165
, pp. 4978-4984
-
-
Migliaccio, M.1
Amacker, M.2
Just, T.3
-
17
-
-
0035437179
-
Transfer of the human telomerase reverse transcriptase (TERT) gene into T lymphocytes results in extension of replicative potential
-
Rufer N, Migliaccio M, Antonchuk J et al. Transfer of the human telomerase reverse transcriptase (TERT) gene into T lymphocytes results in extension of replicative potential. Blood 2001; 98: 597-603.
-
(2001)
Blood
, vol.98
, pp. 597-603
-
-
Rufer, N.1
Migliaccio, M.2
Antonchuk, J.3
-
18
-
-
84899578138
-
mRNA display: From basic principles to macrocycle drug discovery
-
Josephson K, Ricardo A, Szostak JW. mRNA display: from basic principles to macrocycle drug discovery. Drug Discov Today 2014; 19: 388-399.
-
(2014)
Drug Discov Today
, vol.19
, pp. 388-399
-
-
Josephson, K.1
Ricardo, A.2
Szostak, J.W.3
-
19
-
-
84890550726
-
RNA-based tools for nuclear reprogramming and lineage-conversion: Towards clinical applications
-
Bernal JA. RNA-based tools for nuclear reprogramming and lineage-conversion: towards clinical applications. J Cardiovasc Transl Res 2013; 6: 956-968.
-
(2013)
J Cardiovasc Transl Res
, vol.6
, pp. 956-968
-
-
Bernal, J.A.1
-
20
-
-
84885676364
-
ModifiedmRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction
-
Zangi L, Lui KO, von Gise A et al. ModifiedmRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction. Nat Biotechnol 2013; 31: 898-907.
-
(2013)
Nat Biotechnol
, vol.31
, pp. 898-907
-
-
Zangi, L.1
Lui, K.O.2
von Gise, A.3
-
21
-
-
84923775885
-
Efficient delivery and functional expression of transfected modified mRNA in human embryonic stem cell-derived retinal pigmented epithelial cells
-
Hansson ML, Albert S, Gonzalez SL et al. Efficient delivery and functional expression of transfected modified mRNA in human embryonic stem cell-derived retinal pigmented epithelial cells. J Biol Chem 2015; 290: 5661-5672.
-
(2015)
J Biol Chem
, vol.290
, pp. 5661-5672
-
-
Hansson, M.L.1
Albert, S.2
Gonzalez, S.L.3
-
22
-
-
77958536106
-
Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA
-
Warren L, Manos PD, Ahfeldt T et al. Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell 2010; 7: 618-630.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 618-630
-
-
Warren, L.1
Manos, P.D.2
Ahfeldt, T.3
-
23
-
-
84931052681
-
Transient delivery of modified mRNA encoding TERT rapidly extends telomeres in human cells
-
Ramunas J, Yakubov E, Brady JJ et al. Transient delivery of modified mRNA encoding TERT rapidly extends telomeres in human cells. FASEB J 2015; 29: 1930-1939.
-
(2015)
FASEB J
, vol.29
, pp. 1930-1939
-
-
Ramunas, J.1
Yakubov, E.2
Brady, J.J.3
-
24
-
-
83455213653
-
Treatment of advanced leukemia in mice with mRNA engineered T cells
-
Barrett DM, Zhao Y, Liu X et al. Treatment of advanced leukemia in mice with mRNA engineered T cells. Hum Gene Ther 2011; 22: 1575-1586.
-
(2011)
Hum Gene Ther
, vol.22
, pp. 1575-1586
-
-
Barrett, D.M.1
Zhao, Y.2
Liu, X.3
-
25
-
-
77955510549
-
Antitransgene rejection responses contribute to attenuated persistence of adoptively transferred CD20/CD19-specific chimeric antigen receptor redirected T cells in humans
-
Jensen MC, Popplewell L, Cooper LJ et al. Antitransgene rejection responses contribute to attenuated persistence of adoptively transferred CD20/CD19-specific chimeric antigen receptor redirected T cells in humans. Biol Blood Marrow Transplant 2010; 16: 1245-1256.
-
(2010)
Biol Blood Marrow Transplant
, vol.16
, pp. 1245-1256
-
-
Jensen, M.C.1
Popplewell, L.2
Cooper, L.J.3
-
26
-
-
79959914449
-
In vivo persistence, tumor localization, and antitumor activity of CARengineered T cells is enhanced by costimulatory signaling through CD137 (4-1BB)
-
Song DG, Ye Q, Carpenito C et al. In vivo persistence, tumor localization, and antitumor activity of CARengineered T cells is enhanced by costimulatory signaling through CD137 (4-1BB). Cancer Res 2011; 71: 4617-4627.
-
(2011)
Cancer Res
, vol.71
, pp. 4617-4627
-
-
Song, D.G.1
Ye, Q.2
Carpenito, C.3
-
27
-
-
0034667771
-
Immortalization of human CD8+ T cell clones by ectopic expression of telomerase reverse transcriptase
-
Hooijberg E, Ruizendaal JJ, Snijders PJF et al. Immortalization of human CD8+ T cell clones by ectopic expression of telomerase reverse transcriptase. J Immunol 2000; 165: 4239-4245.
-
(2000)
J Immunol
, vol.165
, pp. 4239-4245
-
-
Hooijberg, E.1
Ruizendaal, J.J.2
Snijders, P.J.F.3
-
28
-
-
84907079903
-
Atorvastatin induces T cell proliferation by a telomerase reverse transcriptase (TERT) mediated mechanism
-
Bennaceur K, Atwill M, Al ZN et al. Atorvastatin induces T cell proliferation by a telomerase reverse transcriptase (TERT) mediated mechanism. Atherosclerosis 2014; 236: 312-320.
-
(2014)
Atherosclerosis
, vol.236
, pp. 312-320
-
-
Bennaceur, K.1
Atwill, M.2
Al, Z.N.3
-
29
-
-
12144287161
-
Human telomerase reverse transcriptase-transduced human cytotoxic T cells suppress the growth of human melanoma in immunodeficient mice
-
Verra NC, Jorritsma A, Weijer K et al. Human telomerase reverse transcriptase-transduced human cytotoxic T cells suppress the growth of human melanoma in immunodeficient mice. Cancer Res 2004; 64: 2153-2161.
-
(2004)
Cancer Res
, vol.64
, pp. 2153-2161
-
-
Verra, N.C.1
Jorritsma, A.2
Weijer, K.3
-
30
-
-
79952692821
-
Telomerase and primary T cells: Biology and immortalization for adoptive immunotherapy
-
Barsov EV. Telomerase and primary T cells: biology and immortalization for adoptive immunotherapy. Immunotherapy 2011; 3: 407-421.
-
(2011)
Immunotherapy
, vol.3
, pp. 407-421
-
-
Barsov, E.V.1
-
31
-
-
84876005284
-
CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia
-
Brentjens RJ, Davila ML, Riviere I et al. CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia. Sci Transl Med 2013; 5: 138r-177r.
-
(2013)
Sci Transl Med
, vol.5
, pp. 138r-177r
-
-
Brentjens, R.J.1
Davila, M.L.2
Riviere, I.3
-
32
-
-
84896335556
-
Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia
-
Davila ML, Riviere I, Wang X et al. Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia. Sci Transl Med 2014; 6: 224r-225r.
-
(2014)
Sci Transl Med
, vol.6
, pp. 224r-225r
-
-
Davila, M.L.1
Riviere, I.2
Wang, X.3
-
33
-
-
3042551216
-
Chimeric receptors with 4-1BB signaling capacity provoke potent cytotoxicity against acute lymphoblastic leukemia
-
Imai C, Mihara K, Andreansky M et al. Chimeric receptors with 4-1BB signaling capacity provoke potent cytotoxicity against acute lymphoblastic leukemia. Leukemia 2004; 18: 676-684.
-
(2004)
Leukemia
, vol.18
, pp. 676-684
-
-
Imai, C.1
Mihara, K.2
Andreansky, M.3
-
34
-
-
33845294816
-
CD28 costimulation provided through a CD19-specific chimeric antigen receptor enhances in vivo persistence and antitumor efficacy of adoptively transferred T cells
-
Kowolik CM, Topp MS, Gonzalez S et al. CD28 costimulation provided through a CD19-specific chimeric antigen receptor enhances in vivo persistence and antitumor efficacy of adoptively transferred T cells. Cancer Res 2006; 66: 10995-11004.
-
(2006)
Cancer Res
, vol.66
, pp. 10995-11004
-
-
Kowolik, C.M.1
Topp, M.S.2
Gonzalez, S.3
-
35
-
-
84933513655
-
Human epidermal growth factor receptor 2 (HER2) -specific chimeric antigen receptor-modified T cells for the immunotherapy of HER2-positive sarcoma
-
Ahmed N, Brawley VS, Hegde M et al. Human epidermal growth factor receptor 2 (HER2) -specific chimeric antigen receptor-modified T cells for the immunotherapy of HER2-positive sarcoma. J Clin Oncol 2015; 33: 1688-1696.
-
(2015)
J Clin Oncol
, vol.33
, pp. 1688-1696
-
-
Ahmed, N.1
Brawley, V.S.2
Hegde, M.3
-
36
-
-
84902314288
-
Clinical application of adoptive T cell therapy in solid tumors
-
Chen Z. Clinical application of adoptive T cell therapy in solid tumors. Med Sci Monit 2014; 20: 953-959.
-
(2014)
Med Sci Monit
, vol.20
, pp. 953-959
-
-
Chen, Z.1
-
37
-
-
84897484486
-
CAR T cells for solid tumors: Armed and ready to go?
-
Kakarla S, Gottschalk S. CAR T cells for solid tumors: armed and ready to go? Cancer J 2014; 20: 151-155.
-
(2014)
Cancer J
, vol.20
, pp. 151-155
-
-
Kakarla, S.1
Gottschalk, S.2
-
38
-
-
80051775476
-
T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia
-
Kalos M, Levine BL, Porter DL et al. T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia. Sci Transl Med 2011; 3: 73r-95r.
-
(2011)
Sci Transl Med
, vol.3
, pp. 73r-95r
-
-
Kalos, M.1
Levine, B.L.2
Porter, D.L.3
-
39
-
-
0013927806
-
Determination of the time for population doubling in monolayer cultures
-
Beniumovich MS. Determination of the time for population doubling in monolayer cultures. Biull Eksp Biol Med 1966; 62: 120-123.
-
(1966)
Biull Eksp Biol Med
, vol.62
, pp. 120-123
-
-
Beniumovich, M.S.1
|