What success can teach us about failure: the plasma metabolome of older adults with superior memory and lessons for Alzheimer's disease

Neurobiology of Aging

Volumn 51, Issue , 2017, Pages 148-155

  Mapstone, Mark ^a   Lin, Feng ^b   Nalls, Mike A ^c   Cheema, Amrita K ^d,e   Singleton, Andrew B ^c   Fiandaca, Massimo S ^a   Federoff, Howard J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF ROCHESTER SCHOOL OF NURSING   (United States)

^c NATIONAL INSTITUTE ON AGING   (United States)

^d GEORGETOWN UNIVERSITY   (United States)

^e GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alzheimer's disease; Arginine metabolism; Memory; Metabolomics; Nitric oxide; Oxidative stress

Indexed keywords

3 HYDROXYPALMITOLEYLCARNITINE; 3 NITROTYROSINE; ARGININE; ASPARAGINE; ASPARTIC ACID; CARNITINE; CITRULLINE; HISTAMINE; HYDROXYHEDADECADIENYLCARNITINE; LYSOPHOSPHATIDYLCHOLINE; UNCLASSIFIED DRUG; VALERYLCARNITINE; BIOLOGICAL MARKER; NITRIC OXIDE;

AGED; ALZHEIMER DISEASE; AMINO ACID BLOOD LEVEL; ARTICLE; COGNITIVE AGING; CONTROLLED STUDY; DISEASE CLASSIFICATION; FEMALE; HUMAN; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MEMORY; METABOLITE; METABOLOMICS; MILD COGNITIVE IMPAIRMENT; OXIDATIVE STRESS; PREDICTIVE VALUE; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; SIGNAL TRANSDUCTION; VERY ELDERLY; BLOOD; COGNITIVE DYSFUNCTION; INFLAMMATION; METABOLISM; METABOLOME; PHYSIOLOGY;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; ARGININE; BIOMARKERS; COGNITIVE DYSFUNCTION; FEMALE; HUMANS; INFLAMMATION; MALE; MEMORY; METABOLOME; NITRIC OXIDE; OXIDATIVE STRESS; SIGNAL TRANSDUCTION;

EID: 85007575574     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2016.11.007     Document Type: Article

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