C-type Lectin Mincle Recognizes Glucosyl-diacylglycerol of Streptococcus pneumoniae and Plays a Protective Role in Pneumococcal Pneumonia

PLoS Pathogens

Volumn 12, Issue 12, 2016, Pages

  Behler Janbeck, Friederike ^a   Takano, Tomotsugu ^b   Maus, Regina ^a   Stolper, Jennifer ^a   Jonigk, Danny ^a   Tort Tarrés, Meritxell ^a   Fuehner, Thomas ^a   Prasse, Antje ^a   Welte, Tobias ^a,c   Timmer, Mattie S M ^d   Stocker, Bridget L ^d   Nakanishi, Yoichi ^e   Miyamoto, Tomofumi ^b   Yamasaki, Sho ^b   Maus, Ulrich A ^a,c  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b KYUSHU UNIVERSITY   (Japan)

^c Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH)   (Germany)

^d VICTORIA UNIVERSITY OF WELLINGTON   (New Zealand)

^e KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DIACYLGLYCEROL DERIVATIVE; GLUCOSYLDIACYLGLYCEROL; GLYCOLIPID; INTERLEUKIN 10; INTERLEUKIN 1BETA; LECTIN; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; CLEC4D PROTEIN, HUMAN; CLECSF8 PROTEIN, MOUSE; GLUCOSYL DIACYLGLYCEROL; IMMUNOGLOBULIN RECEPTOR; MEMBRANE PROTEIN;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL LOAD; BACTERICIDAL ACTIVITY; BRONCHOALVEOLAR LAVAGE FLUID; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOKINE RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; MASS FRAGMENTOGRAPHY; MOUSE; NECROSIS; NONHUMAN; PHAGOCYTOSIS; PROTEIN PURIFICATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STREPTOCOCCUS PNEUMONIA; ANIMAL; C57BL MOUSE; FLOW CYTOMETRY; IMMUNOLOGY; KNOCKOUT MOUSE; LUNG ALVEOLUS MACROPHAGE; METABOLISM; NEUTROPHIL; STREPTOCOCCUS PNEUMONIAE;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FLOW CYTOMETRY; GLYCOLIPIDS; HUMANS; IMMUNOPHENOTYPING; LECTINS, C-TYPE; MACROPHAGES, ALVEOLAR; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEUTROPHILS; PNEUMONIA, PNEUMOCOCCAL; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, IMMUNOLOGIC; STREPTOCOCCUS PNEUMONIAE;

EID: 85007575283     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1006038     Document Type: Article

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