Macrophage turnover kinetics in the lungs of mice infected with Streptococcus pneumoniae

American Journal of Respiratory Cell and Molecular Biology

Volumn 38, Issue 1, 2008, Pages 105-113

  Taut, Katharina ^a   Winter, Christine ^a   Briles, David E ^b   Paton, James C ^c   Christman, John W ^d   Maus, Regina ^a   Baumann, Rolf ^a   Welte, Tobias ^a   Maus, Ulrich A ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b University of Alabama at Birmingham   (United States)

^c UNIVERSITY OF ADELAIDE   (Australia)

^d UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Infection; Lung; Macrophage; Monocyte; Turnover

Indexed keywords

ALLOANTIGEN; CD45 ANTIGEN; PROTEIN TYROSINE PHOSPHATASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; BONE MARROW TRANSPLANTATION; CHIMERA; CONTROLLED STUDY; LUNG ALVEOLUS MACROPHAGE; LUNG EXTRAVASCULAR FLUID; LUNG LAVAGE; LUNG PARENCHYMA; MACROPHAGE FUNCTION; MOUSE; NONHUMAN; STREPTOCOCCUS PNEUMONIA; STREPTOCOCCUS PNEUMONIAE;

ANIMALS; ANTIGENS, CD45; APOPTOSIS; BONE MARROW TRANSPLANTATION; BRONCHOALVEOLAR LAVAGE FLUID; FEMALE; HUMANS; KINETICS; MACROPHAGES, ALVEOLAR; MALE; MICE; MICE, TRANSGENIC; NECROSIS; PNEUMONIA, PNEUMOCOCCAL; PULMONARY ALVEOLI; STREPTOCOCCUS PNEUMONIAE; TIME FACTORS; TRANSPLANTATION CHIMERA; WHOLE-BODY IRRADIATION;

MUS; STREPTOCOCCUS PNEUMONIAE;

EID: 37549004805     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2007-0132OC     Document Type: Article

References (21)

1. Paton JC. The contribution of pneumolysin to the pathogenicity of streptococcus pneumoniae. Trends Microbiol 1996;4:103-106.
2. Paton JC, Lock RA, Lee CJ, Li JP, Berry AM, Mitchell TJ, Andrew PW, Hansman D, Boulnois GJ. Purification and immunogenicity of genetically obtained pneumolysin toxoids and their conjugation to streptococcus pneumoniae type 19f polysaccharide. Infect Immun 1991;59:2297-2304.
3. Maus UA, Srivastava M, Paton JC, Mack M, Everhart MB, Blackwell TS, Christman JW, Schlondorff D, Seeger W, Lohmeyer J. Pneumolysin-induced lung injury is independent of leukocyte trafficking into the alveolar space. J Immunol 2004;173:1307-1312.
4. Malley R, Henneke P, Morse SC, Cieslewicz MJ, Lipsitch M, Thompson CM, Kurt-Jones E, Paton JC, Wessels MR, Golenbock DT. Recognition of pneumolysin by toll-like receptor 4 confers resistance to pneumococcal infection. Proc Natl Acad Sci USA 2003;100:1966-1971.
5. Knapp S, Leemans JC, Florquin S, Branger J, Maris NA, Pater J, van Rooijen N, van der Poll T. Alveolar macrophages have a protective antiinflammatory role during murine pneumococcal pneumonia. Am J Respir Crit Care Med 2003;167:171-179.
6. Maus UA, Backi M, Winter C, Srivastava M, Schwarz MK, Ruckle T, Paton JC, Briles D, Mack M, Welte T, et al. Importance of phosphoinositide 3-kinase gamma in the host defense against pneumococcal infection. Am J Respir Crit Care Med 2007;175:958-966.
7. Maus UA, Janzen S, Wall G, Srivastava M, Blackwell TS, Christman JW, Seeger W, Welte T, Lohmeyer J. Resident alveolar macrophages are replaced by recruited monocytes in response to endotoxin-induced lung inflammation. Am J Respir Cell Mol Biol 2006;35:227-235.
8. Camps M, Ruckle T, Ji H, Ardissone V, Rintelen F, Shaw J, Ferrandi C, Chabert C, Gillieron C, Francon B, et al. Blockade of pi3kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis. Nat Med 2005;11:936-943.
9. Morse HC III. Genetic nomenclature for loci controlling surface antigens of mouse hemopoietic cells. J Immunol 1992;149:3129-3134.
10. Briles DE, Hollingshead SK, Paton JC, Ades EW, Novak L, van Ginkel FW, Benjamin WH Jr. Immunizations with pneumococcal surface protein a and pneumolysin are protective against pneumonia in a murine model of pulmonary infection with streptococcus pneumoniae. J Infect Dis 2003;188:339-348.
11. Srivastava M, Meinders A, Steinwede K, Maus R, Lucke N, Buhling F, Ehlers S, Welte T, Maus UA. Mediator responses of alveolar macrophages and kinetics of mononuclear phagocyte subset recruitment during acute primary and secondary mycobacterial infections in the lungs of mice. Cell Microbiol 2007;9:738-752.
12. Winter C, Taut K, Srivastava M, Langer F, Mack M, Briles DE, Paton JC, Maus R, Welte T, Gunn MD, et al. Lung-specific overexpression of cc chemokine ligand (ccl) 2 enhances the host defense to streptococcus pneumoniae infection in mice: Role of the ccl2-ccr2 axis. J Immunol 2007;178:5828-5838.
13. Maus U, Herold S, Muth H, Maus R, Ermert L, Ermert M, Weissmann N, Rosseau S, Seeger W, Grimminger F, et al. Monocytes recruited into the alveolar air space of mice show a monocytic phenotype but upregulate cd14. Am J Physiol Lung Cell Mol Physiol 2001;280:L58-L68.
14. Landsman L, Varol C, Jung S. Distinct differentiation potential of blood monocyte subsets in the lung. J Immunol 2007;178:2000-2007.
15. Rubins JB, Charboneau D, Fasching C, Berry AM, Paton JC, Alexander JE, Andrew PW, Mitchell TJ, Janoff EN. Distinct roles for pneumolysin's cytotoxic and complement activities in the pathogenesis of pneumococcal pneumonia. Am J Respir Crit Care Med 1996;153:1339-1346.
16. Everhart MB, Han W, Parman KS, Polosukhin VV, Zeng H, Sadikot RT, Li B, Yull FE, Christman JW, Blackwell TS. Intratracheal administration of liposomal clodronate accelerates alveolar macrophage reconstitution following fetal liver transplantation. J Leukoc Biol 2005;77:173-180.
17. Ojielo CI, Cooke K, Mancuso P, Standiford TJ, Olkiewicz KM, Clouthier S, Corrion L, Ballinger MN, Toews GB, Paine R III, et al. Defective phagocytosis and clearance of Pseudomonas aeruginosa in the lung following bone marrow transplantation. J Immunol 2003;171:4416-4424.
18. Dockrell DH, Marriott HM, Prince LR, Ridger VC, Ince PG, Hellewell PG, Whyte MK. Alveolar macrophage apoptosis contributes to pneumococcal clearance in a resolving model of pulmonary infection. J Immunol 2003;171:5380-5388.
19. Marriott HM, Dockrell DH. Streptococcus pneumoniae: the role of apoptosis in host defense and pathogenesis. Int J Biochem Cell Biol 2006;38:1848-1854.
20. Marriott HM, Hellewell PG, Cross SS, Ince PG, Whyte MK, Dockrell DH. Decreased alveolar macrophage apoptosis is associated with increased pulmonary inflammation in a murine model of pneumococcal pneumonia. J Immunol 2006;177:6480-6488.
21. Ali F, Lee ME, Iannelli F, Pozzi G, Mitchell TJ, Read RC, Dockrell DH. Streptococcus pneumoniae-associated human macrophage apoptosis after bacterial internalization via complement and fcgamma receptors correlates with intracellular bacterial load. J Infect Dis 2003;188:1119-1131.