Mechanism for recognition of an unusual mycobacterial glycolipid by the macrophage receptor mincle

Journal of Biological Chemistry

Volumn 288, Issue 40, 2013, Pages 28457-28465

  Feinberg, Hadar ^a   Jégouzo, Sabine A F ^b   Rowntree, Thomas J W ^b   Guan, Yue ^b   Brash, Matthew A ^b   Taylor, Maureen E ^b   Weis, William I ^a   Drickamer, Kurt ^b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCO LIPIDS; HYDROCARBON TAIL; MYCOBACTERIAL; PERSISTENT INFECTION;

BIOCHEMISTRY; BIOLOGY;

MACROPHAGES;

CALCIUM ION; CORD FACTOR; GLUCOSE; GLYCOLIPID; LECTIN; MINCLE; TREHALOSE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL STRAIN; BINDING AFFINITY; BINDING ASSAY; BINDING SITE; CONTROLLED STUDY; ESCHERICHIA COLI; MACROPHAGE; MOLECULAR RECOGNITION; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SITE DIRECTED MUTAGENESIS; STAPHYLOCOCCUS AUREUS; WILD TYPE;

CARBOHYDRATE-BINDING PROTEIN; CLEC4E; CORD FACTOR; CRYSTAL STRUCTURE; GLYCOBIOLOGY; GLYCOLIPIDS; MYCOBACTERIUM TUBERCULOSIS;

AMINO ACID SEQUENCE; AMINO ACIDS; ANIMALS; BINDING SITES; CATTLE; CRYSTALLOGRAPHY, X-RAY; GLUCOSE; GLYCOLIPIDS; HYDROGEN-ION CONCENTRATION; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LECTINS, C-TYPE; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MYCOBACTERIUM; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, IMMUNOLOGIC; TREHALOSE;

EID: 84885170440     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.497149     Document Type: Article

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