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Volumn 7, Issue 52, 2016, Pages 86161-86173

Aberrant overexpression of ADAR1 promotes gastric cancer progression by activating mTOR/p70S6K signaling

Author keywords

ADAR1; Gastric cancer; Metastasis; MTOR; Tumorigenecity

Indexed keywords

ADENOSINE DEAMINASE; ADENOSINE DEAMINASE ACTING ON RNA 1; MAMMALIAN TARGET OF RAPAMYCIN; S6 KINASE; UNCLASSIFIED DRUG; ADAR1 PROTEIN, HUMAN; MTOR PROTEIN, HUMAN; RNA BINDING PROTEIN; TARGET OF RAPAMYCIN KINASE;

EID: 85007464316     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.13354     Document Type: Article
Times cited : (20)

References (40)
  • 1
    • 84952935440 scopus 로고    scopus 로고
    • Elucidating the cancerspecific genetic alteration spectrum of glioblastoma derived cell lines from whole exome and RNA sequencing
    • Patil V, Pal J, Somasundaram K. Elucidating the cancerspecific genetic alteration spectrum of glioblastoma derived cell lines from whole exome and RNA sequencing. Oncotarget. 2015; 6:43452-43471. doi: 10.18632/oncotarget.6171
    • (2015) Oncotarget , vol.6 , pp. 43452-43471
    • Patil, V.1    Pal, J.2    Somasundaram, K.3
  • 3
    • 12344300804 scopus 로고    scopus 로고
    • Widespread A-to-I RNA editing of Alu-containing mRNAs in the human transcriptome
    • Athanasiadis A, Rich A, Maas S. Widespread A-to-I RNA editing of Alu-containing mRNAs in the human transcriptome. PLoS Biol. 2004; 2:e391. doi: 10.18632/oncotarget.7441
    • (2004) PLoS Biol , vol.2
    • Athanasiadis, A.1    Rich, A.2    Maas, S.3
  • 4
    • 33845315229 scopus 로고    scopus 로고
    • Editor meets silencer: crosstalk between RNA editing and RNA interference
    • Nishikura K. Editor meets silencer: crosstalk between RNA editing and RNA interference. Nat Rev Mol Cell Biol. 2006; 7:919-931
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 919-931
    • Nishikura, K.1
  • 6
    • 33646266509 scopus 로고    scopus 로고
    • Phytochrome-mediated agravitropism in Arabidopsis hypocotyls requires GIL1 and confers a fitness advantage
    • Allen T, Ingles PJ, Praekelt U, Smith H, Whitelam GC. Phytochrome-mediated agravitropism in Arabidopsis hypocotyls requires GIL1 and confers a fitness advantage. Plant J. 2006; 46:641-648
    • (2006) Plant J , vol.46 , pp. 641-648
    • Allen, T.1    Ingles, P.J.2    Praekelt, U.3    Smith, H.4    Whitelam, G.C.5
  • 7
    • 72849106592 scopus 로고    scopus 로고
    • RNA processing and its regulation: global insights into biological networks
    • Licatalosi DD, Darnell RB. RNA processing and its regulation: global insights into biological networks. Nat Rev Genet. 2010; 11:75-87
    • (2010) Nat Rev Genet , vol.11 , pp. 75-87
    • Licatalosi, D.D.1    Darnell, R.B.2
  • 8
    • 0033603359 scopus 로고    scopus 로고
    • Serotonin-2C receptor pre-mRNA editing in rat brain and in vitro by splice site variants of the interferon-inducible double-stranded RNAspecific adenosine deaminase ADAR1
    • Liu Y, Emeson RB, Samuel CE. Serotonin-2C receptor pre-mRNA editing in rat brain and in vitro by splice site variants of the interferon-inducible double-stranded RNAspecific adenosine deaminase ADAR1. J Biol Chem. 1999; 274:18351-18358
    • (1999) J Biol Chem , vol.274 , pp. 18351-18358
    • Liu, Y.1    Emeson, R.B.2    Samuel, C.E.3
  • 9
    • 0033582534 scopus 로고    scopus 로고
    • Editing of glutamate receptor subunit B pre-mRNA by splice-site variants of interferon-inducible double-stranded RNA-specific adenosine deaminase ADAR1
    • Liu Y, Samuel CE. Editing of glutamate receptor subunit B pre-mRNA by splice-site variants of interferon-inducible double-stranded RNA-specific adenosine deaminase ADAR1. J Biol Chem. 1999; 274:5070-5077
    • (1999) J Biol Chem , vol.274 , pp. 5070-5077
    • Liu, Y.1    Samuel, C.E.2
  • 10
    • 37049036590 scopus 로고    scopus 로고
    • RNA editing of the human herpesvirus 8 kaposin transcript eliminates its transforming activity and is induced during lytic replication
    • Gandy SZ, Linnstaedt SD, Muralidhar S, Cashman KA, Rosenthal LJ, Casey JL. RNA editing of the human herpesvirus 8 kaposin transcript eliminates its transforming activity and is induced during lytic replication. J Virol. 2007; 81:13544-13551
    • (2007) J Virol , vol.81 , pp. 13544-13551
    • Gandy, S.Z.1    Linnstaedt, S.D.2    Muralidhar, S.3    Cashman, K.A.4    Rosenthal, L.J.5    Casey, J.L.6
  • 11
    • 0029940185 scopus 로고    scopus 로고
    • RNA editing of hepatitis delta virus antigenome by dsRNA-adenosine deaminase
    • Polson AG, Bass BL, Casey JL. RNA editing of hepatitis delta virus antigenome by dsRNA-adenosine deaminase. Nature. 1996; 380:454-456
    • (1996) Nature , vol.380 , pp. 454-456
    • Polson, A.G.1    Bass, B.L.2    Casey, J.L.3
  • 12
    • 0023763122 scopus 로고
    • Biased hypermutation and other genetic changes in defective measles viruses in human brain infections
    • Cattaneo R, Schmid A, Eschle D, Baczko K, ter Meulen V, Billeter MA. Biased hypermutation and other genetic changes in defective measles viruses in human brain infections. Cell. 1988; 55:255-265
    • (1988) Cell , vol.55 , pp. 255-265
    • Cattaneo, R.1    Schmid, A.2    Eschle, D.3    Baczko, K.4    ter Meulen, V.5    Billeter, M.A.6
  • 13
    • 18144401994 scopus 로고    scopus 로고
    • New antiviral pathway that mediates hepatitis C virus replicon interferon sensitivity through ADAR1
    • Taylor DR, Puig M, Darnell ME, Mihalik K, Feinstone SM. New antiviral pathway that mediates hepatitis C virus replicon interferon sensitivity through ADAR1. J Virol. 2005; 79:6291-6298
    • (2005) J Virol , vol.79 , pp. 6291-6298
    • Taylor, D.R.1    Puig, M.2    Darnell, M.E.3    Mihalik, K.4    Feinstone, S.M.5
  • 14
    • 0034032599 scopus 로고    scopus 로고
    • Molecular interactions and metal binding in the theophylline-binding core of an RNA aptamer
    • Zimmermann GR, Wick CL, Shields TP, Jenison RD, Pardi A. Molecular interactions and metal binding in the theophylline-binding core of an RNA aptamer. RNA. 2000; 6:659-667
    • (2000) RNA , vol.6 , pp. 659-667
    • Zimmermann, G.R.1    Wick, C.L.2    Shields, T.P.3    Jenison, R.D.4    Pardi, A.5
  • 15
    • 0034722628 scopus 로고    scopus 로고
    • Human RNA-specific adenosine deaminase (ADAR1) gene specifies transcripts that initiate from a constitutively active alternative promoter
    • Kawakubo K, Samuel CE. Human RNA-specific adenosine deaminase (ADAR1) gene specifies transcripts that initiate from a constitutively active alternative promoter. Gene. 2000; 258:165-172
    • (2000) Gene , vol.258 , pp. 165-172
    • Kawakubo, K.1    Samuel, C.E.2
  • 16
    • 0029164692 scopus 로고
    • Expression and regulation by interferon of a double-stranded-RNA-specific adenosine deaminase from human cells: evidence for two forms of the deaminase
    • Patterson JB, Samuel CE. Expression and regulation by interferon of a double-stranded-RNA-specific adenosine deaminase from human cells: evidence for two forms of the deaminase. Mol Cell Biol. 1995; 15:5376-5388
    • (1995) Mol Cell Biol , vol.15 , pp. 5376-5388
    • Patterson, J.B.1    Samuel, C.E.2
  • 17
    • 17644368606 scopus 로고    scopus 로고
    • Expression of interferon-inducible RNA adenosine deaminase ADAR1 during pathogen infection and mouse embryo development involves tissue-selective promoter utilization and alternative splicing
    • George CX, Wagner MV, Samuel CE. Expression of interferon-inducible RNA adenosine deaminase ADAR1 during pathogen infection and mouse embryo development involves tissue-selective promoter utilization and alternative splicing. J Biol Chem. 2005; 280:15020-15028
    • (2005) J Biol Chem , vol.280 , pp. 15020-15028
    • George, C.X.1    Wagner, M.V.2    Samuel, C.E.3
  • 25
    • 84886060209 scopus 로고    scopus 로고
    • ADAR1 regulates ARHGAP26 gene expression through RNA editing by disrupting miR-30b-3p and miR-573 binding
    • Wang Q, Hui H, Guo Z, Zhang W, Hu Y, He T, Tai Y, Peng P, Wang L. ADAR1 regulates ARHGAP26 gene expression through RNA editing by disrupting miR-30b-3p and miR-573 binding. RNA. 2013; 19:1525-1536
    • (2013) RNA , vol.19 , pp. 1525-1536
    • Wang, Q.1    Hui, H.2    Guo, Z.3    Zhang, W.4    Hu, Y.5    He, T.6    Tai, Y.7    Peng, P.8    Wang, L.9
  • 27
    • 84924352056 scopus 로고    scopus 로고
    • Genomic analysis of ADAR1 binding and its involvement in multiple RNA processing pathways
    • Bahn JH, Ahn J, Lin X, Zhang Q, Lee JH, Civelek M, Xiao X. Genomic analysis of ADAR1 binding and its involvement in multiple RNA processing pathways. Nat Commun. 2015; 6:6355
    • (2015) Nat Commun , vol.6 , pp. 6355
    • Bahn, J.H.1    Ahn, J.2    Lin, X.3    Zhang, Q.4    Lee, J.H.5    Civelek, M.6    Xiao, X.7
  • 28
    • 84955695193 scopus 로고    scopus 로고
    • A-to-I editing of coding and non-coding RNAs by ADARs
    • Nishikura K. A-to-I editing of coding and non-coding RNAs by ADARs. Nat Rev Mol Cell Biol. 2016; 17:83-96
    • (2016) Nat Rev Mol Cell Biol , vol.17 , pp. 83-96
    • Nishikura, K.1
  • 32
    • 84880360716 scopus 로고    scopus 로고
    • Characterization and comparison of human nuclear and cytosolic editomes
    • Chen L. Characterization and comparison of human nuclear and cytosolic editomes. Proc Natl Acad Sci USA 2013; 110:E2741-2747
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. E2741-E2747
    • Chen, L.1
  • 34
    • 33846707308 scopus 로고    scopus 로고
    • p150 ADAR1 isoform involved in maintenance of HeLa cell proliferation
    • Wang H, Hou Z, Wu Y, Ma X, Luo X. p150 ADAR1 isoform involved in maintenance of HeLa cell proliferation. BMC cancer. 2006; 6:282
    • (2006) BMC cancer , vol.6 , pp. 282
    • Wang, H.1    Hou, Z.2    Wu, Y.3    Ma, X.4    Luo, X.5
  • 35
    • 84912123676 scopus 로고    scopus 로고
    • Growing knowledge of the mTOR signaling network
    • Huang K, Fingar DC. Growing knowledge of the mTOR signaling network. Semin Cell Dev Biol. 2014; 36:79-90
    • (2014) Semin Cell Dev Biol , vol.36 , pp. 79-90
    • Huang, K.1    Fingar, D.C.2
  • 36
    • 84935071817 scopus 로고    scopus 로고
    • The expanding role of mTOR in cancer cell growth and proliferation
    • Cargnello M, Tcherkezian J, Roux PP. The expanding role of mTOR in cancer cell growth and proliferation. Mutagenesis. 2015; 30:169-176
    • (2015) Mutagenesis , vol.30 , pp. 169-176
    • Cargnello, M.1    Tcherkezian, J.2    Roux, P.P.3
  • 37
    • 84973520321 scopus 로고    scopus 로고
    • A positive feedback loop involving EGFR/Akt/mTORC1 and IKK/NF-kB regulates head and neck squamous cell carcinoma proliferation
    • Li Z, Yang Z, Passaniti A, Lapidus RG, Liu X, Cullen KJ, Dan HC. A positive feedback loop involving EGFR/Akt/mTORC1 and IKK/NF-kB regulates head and neck squamous cell carcinoma proliferation. Oncotarget. 2016; 7:31892-31906
    • (2016) Oncotarget , vol.7 , pp. 31892-31906
    • Li, Z.1    Yang, Z.2    Passaniti, A.3    Lapidus, R.G.4    Liu, X.5    Cullen, K.J.6    Dan, H.C.7
  • 39
    • 84929911595 scopus 로고    scopus 로고
    • Expression and clinical significance of mammalian target of rapamycin/P70 ribosomal protein S6 kinase signaling pathway in human colorectal carcinoma tissue
    • Lu Q, Wang J, Yu G, Guo T, Hu C, Ren P. Expression and clinical significance of mammalian target of rapamycin/P70 ribosomal protein S6 kinase signaling pathway in human colorectal carcinoma tissue. Oncol Lett. 2015; 10:277-282
    • (2015) Oncol Lett , vol.10 , pp. 277-282
    • Lu, Q.1    Wang, J.2    Yu, G.3    Guo, T.4    Hu, C.5    Ren, P.6
  • 40
    • 84978134352 scopus 로고    scopus 로고
    • Zinc finger protein 91 (ZFP91) activates HIF-1alpha via NF-kappaB/p65 to promote proliferation and tumorigenesis of colon cancer
    • Ma J, Mi C, Wang KS, Lee JJ, Jin X. Zinc finger protein 91 (ZFP91) activates HIF-1alpha via NF-kappaB/p65 to promote proliferation and tumorigenesis of colon cancer. Oncotarget. 2016; 7:36551-36562. doi: 10.18632/oncotarget.9070
    • (2016) Oncotarget , vol.7 , pp. 36551-36562
    • Ma, J.1    Mi, C.2    Wang, K.S.3    Lee, J.J.4    Jin, X.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.