Injury-stimulated Sonic hedgehog expression in microglia contributes to neuroinflammatory response in the MPTP model of Parkinson's disease

Biochemical and Biophysical Research Communications

Volumn 482, Issue 4, 2017, Pages 980-986

  Lee, Jeong Hwi ^a,b   Chung, Young Cheul ^b   Bok, Eugene ^b   Lee, Hankyu ^a   Huh, Sue Hee ^b   Lee, Ji Eun ^c   Jin, Byung Kwan ^b   Ko, Hyuk Wan ^a  

^a Dongguk University   (South Korea)

^b Kyung Hee University Hospital   (South Korea)

^c Sungkyunkwan University   (South Korea)

Author keywords

Microglia; MPTP; Parkinson's disease; Sonic hedgehog

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; SONIC HEDGEHOG PROTEIN; LIPOPOLYSACCHARIDE; SHH PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; C57BL 6 MOUSE; CELL ACTIVATION; CONTROLLED STUDY; EXPERIMENTAL BRAIN INJURY; IN VIVO STUDY; MALE; MICROGLIA; MICROGLIAL CELL CULTURE; MOUSE; MPTP-INDUCED PARKINSONISM; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; C57BL MOUSE; CELL CULTURE; DISEASE MODEL; GENETICS; IMMUNOLOGY; INFLAMMATION; METABOLISM; PARKINSON DISEASE; PATHOLOGY; SUBSTANTIA NIGRA; UPREGULATION;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ANIMALS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; HEDGEHOG PROTEINS; INFLAMMATION; LIPOPOLYSACCHARIDES; MALE; MICE, INBRED C57BL; MICROGLIA; PARKINSON DISEASE, SECONDARY; SUBSTANTIA NIGRA; UP-REGULATION;

EID: 85007436473     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2016.11.144     Document Type: Article

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