Theory-Based Interventions to Improve Medication Adherence in Older Adults Prescribed Polypharmacy: A Systematic Review

Drugs and Aging

Volumn 34, Issue 2, 2017, Pages 97-113

  Patton, Deborah E ^a   Hughes, Carmel M ^a   Cadogan, Cathal A ^a,b   Ryan, Cristín A ^a,b  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

BEHAVIOR CHANGE; CLINICAL OUTCOME; DATA BASE; HEALTH BELIEF MODEL; HUMAN; MEDICATION COMPLIANCE; POLYPHARMACY; PRIORITY JOURNAL; PSYCHOLOGICAL THEORY; REVIEW; RISK FACTOR; SELF REGULATION MODEL; SOCIAL COGNITIVE THEORY; SYSTEMATIC REVIEW; ADULT; AGED; MEDICATION THERAPY MANAGEMENT; ORGANIZATION AND MANAGEMENT; PATIENT EDUCATION; PATIENT PARTICIPATION; PSYCHOLOGICAL MODEL; PSYCHOLOGY; STATISTICS AND NUMERICAL DATA;

ADULT; AGED; HUMANS; MEDICATION ADHERENCE; MEDICATION THERAPY MANAGEMENT; MODELS, PSYCHOLOGICAL; PATIENT EDUCATION AS TOPIC; PATIENT PARTICIPATION; POLYPHARMACY;

EID: 85007212220     PISSN: 1170229X     EISSN: 11791969     Source Type: Journal    
DOI: 10.1007/s40266-016-0426-6     Document Type: Review

References (83)

1. Barnett K, Mercer SW, Norbury M, et al. Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study. Lancet. 2012;380:37–43. doi:10.1016/S0140-6736(12)60240-2.
2. Salive ME. Multimorbidity in older adults. Epidemiol Rev. 2013;35:75–83.
3. Tinetti ME, Fried TR, Boyd CM. Designing health care for the most common chronic condition—multimorbidity. JAMA. 2014;307:2493–5.
4. Guthrie B, Makubate B, Hernandez-Santiago V, et al. The rising tide of polypharmacy and drug–drug interactions: population database analysis 1995–2010. BMC Med. 2015;13:74. doi:10.1186/s12916-015-0322-7.
5. Duerden M, Payne R. Polypharmacy and medicines optimisation: making it safe and sound. The Kings Fund. 2013. http://www.kingsfund.org.uk/publications. Accessed 20 Feb 2016.
6. Rollason V, Vogt N. Reduction of polypharmacy in the elderly: a systematic review of the role of the pharmacist. Drugs Aging. 2003;20:817–32.
7. Patterson S, Cadogen C, Kerse N, et al. Interventions to improve the appropriate use of polypharmacy for older people. Cochrane Database Syst Rev. 2015;(10):CD008165. doi:10.1002/14651858.CD008165.pub3.
8. Sabate E. Adherence to long-term therapies: evidence for action. World Health Organisation (WHO). 2003. http://www.who.int/chp/knowledge/publications/adherence_report/en/. Accessed 28 June 2016.
9. Kardas P, Lewek P, Matyjaszczyk M. Determinants of patient adherence: a review of systematic reviews. Front Pharmacol. 2013;4:91. doi:10.3389/fphar.2013.00091.
10. Linjakumpu T, Hartikainen S, Klaukka T, et al. Use of medications and polypharmacy are increasing among the elderly. J Clin Epidemiol. 2002;55:809–17.
11. Ingersoll KS, Cohen J. The impact of medication regimen factors on adherence to chronic treatment: a review of literature. J Behav Med. 2008;31:213–24.
12. Lehane E, McCarthy G. Intentional and unintentional medication non-adherence: a comprehensive framework for clinical research and practice? A discussion paper. Int J Nurs Stud. 2007;44:1468–77.
13. Claxton AJ, Cramer J, Pierce CA. A systematic review of the associations between dose regimens and medication compliance. Clin Ther. 2001;23:1296–310.
14. Gellad WF, Grenard JL, Marcum ZA. A systematic review of barriers to medication adherence in the elderly: looking beyond cost and regimen complexity. Am J Geriatr Pharmacother. 2012;9:11–23.
15. Malhotra S, Karan RS, Pandhi P, et al. Drug related medical emergencies in the elderly: role of adverse drug reactions and non-compliance. Postgrad Med J. 2001;913:703–7.
16. DiMatteo MR, Giordani PJ, Lepper HS, et al. Patient adherence and medical treatment outcomes: a meta-analysis. Med Care. 2002;40:794–811.
17. Nieuwlaat R, Wilczynski N, Navarro T, et al. Interventions for enhancing medication adherence, Cochrane Database Syst Rev. 2014;(11):CD000011. doi:10.1002/14651858.CD000011.pub4.
18. Farmer KC. Contemporary issues: methods for measuring and monitoring medication regimen adherence in clinical trials and clinical practice. Clin Ther. 1999;21:1074–90.
19. Horne R, Weinman J, Barber N, et al. Concordance, adherence and compliance in medicine taking, National Coordinating Centre for the Service Delivery and Organisation (NCCSDO). 2005. http://www.netscc.ac.uk/hsdr/files/project/SDO_FR_08-1412-076_V01.pdf. Accessed 28 June 2016.
20. Garfield S, Clifford S, Eliasson L, et al. Suitability of measures of self-reported medication adherence for routine clinical use: a systematic review. BMC Med Res Methodol. 2011;11:149. doi:10.1186/1471-2288-11-149.
21. Karve S, Cleves MA, Helm M, et al. Good and poor adherence: optimal cut-point for adherence measures using administrative claims data. Curr Med Res Opin. 2009;25:2303–10.
22. Craig P, Dieppe P, Macintyre S, et al. Developing and evaluating complex interventions: the new Medical Research Council guidance. BMJ. 2008;337:979–83.
23. Michie SF, Atkins L, West R. The behaviour change wheel: a guide to designing interventions. London: Silverback Publishing; 2015.
24. Michie SF, West R, Campbell R, et al. ABC of behaviour change theories. London: Silverback Publishing; 2014.
25. Glanz K, Rimer BK. Theory at a glance: a guide for health promotion practice. San Francisco: NIH National Cancer Institute; 2005.
26. Ayling K, Brierley S, Johnson B, et al. Efficacy of theory-based interventions for young people with type 1 diabetes: a systematic review and meta-analysis. Br J Health Psychol. 2015;20:428–46.
27. Michie S, Prestwich A. Are interventions theory-based? Development of a theory coding scheme. Health Psychol. 2010;29:1–8.
28. Albarracín D, Gillette JC, Earl AN, et al. A test of major assumptions about behavior change: a comprehensive look at the effects of passive and active HIV-prevention interventions since the beginning of the epidemic. Psychol Bull. 2005;131:856. doi:10.1037/0033-2909.131.6.856.
29. Baban A, Craciun C. Changing health-risk behaviors: a review of theory and evidence-based interventions in health psychology. J Cogn Behav Psychother. 2007;7:45–67.
30. Conn VS, Enriquez M, Ruppar TM, et al. Meta-analyses of theory use in medication adherence intervention research. Am J Health Behav. 2016;40:155–71.
31. Farmer AJ, McSharry J, Rowbotham S, et al. Effects of interventions promoting monitoring of medication use and brief messaging on medication adherence for people with type 2 diabetes: a systematic review of randomized trials. Diabet Med. 2015;33:565–79. doi:10.1111/dme.12987.
32. Prestwich A, Sniehotta FF, Whittington C, et al. Does theory influence the effectiveness of health behavior interventions? Meta-analysis. Health Psychol. 2014;33:465. doi:10.1037/a0032853.
33. Webb T, Joseph J, Yardley L, et al. Using the internet to promote health behavior change: a systematic review and meta-analysis of the impact of theoretical basis, use of behavior change techniques, and mode of delivery on efficacy. J Med Internet Res. 2010;12:e4. doi:10.2196/jmir.1376.
34. The Cochrane Collaboration. Cochrane handbook for systematic reviews of interventions, Version 5.1.0, 2011. http://www.cochrane-handbook.org. Accessed 12 Dec 2015.
35. Moher D, Liberati A, Tetzlaff J, et al. The PRISMA Group (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PloS Med. 2009;6:e1000097. doi:10.1371/journal.pmed1000097.
36. Effective Practice and Organisation of Care (EPOC). EPOC Resources for review authors, Norwegian Knowledge Centre for the Health Services. 2015. http://epoc.cochrane.org/epoc-specific-resources-review-authors. Accessed 12 Dec 2015.
37. Sansone RA, Sansone LA. Alcohol/Substance misuse and treatment nonadherence: fatal attraction. Psychiatry (Edgmont). 2008;5:43.
38. Solomon DH, Iversen MD, Avorn J, et al. Osteoporosis telephonic intervention to improve medication regimen adherence: a large, pragmatic, randomized controlled trial. Arch Intern Med. 2012;172:477–83.
39. Barnason S, Zimmerman L, Hertzog M, et al. Pilot testing of a medication self-management transition intervention for heart failure patients. West J Nurs Res. 2010;32:849–70.
40. Ruppar TM. Randomized pilot study of a behavioral feedback intervention to improve medication adherence in older adults with hypertension. J Cardiovasc Nurs. 2010;25:470–9.
41. Williams A, Manias E, Walker R, et al. A multifactorial intervention to improve blood pressure control in co-existing diabetes and kidney disease: a feasibility randomized controlled trial. J Adv Nurs. 2012;68:2515–25.
42. O’Carroll RE, Chambers JA, Dennis M, et al. Improving adherence to medication in stroke survivors: a pilot randomised controlled trial. Ann Behav Med. 2013;46:358–68.
43. Lancaster GA. Pilot and feasibility studies come of age! Pilot Feasibility Stud. 2015;1:1. doi:10.1186/2055-5784-1-1.
44. Solomon DH, Gleeson T, Iversen M, et al. A blinded randomized controlled trial of motivational interviewing to improve adherence with osteoporosis medications: design of the OPTIMA trial. Osteoporos Int. 2010;21:137–44.
45. Horne R, Weinman J, Hankins M. The beliefs about medicines questionnaire: the development and evaluation of a new method for assessing the cognitive representation of medication. Psychol Health. 1999;14:1–24.
46. Morisky DE, Green LW, Levine DM. Concurrent and predictive validity of a self-reported measure of medication adherence. Med Care. 1986;24:67–74.
47. Green CP, Porter CB, Bresnahan DR, et al. Development and evaluation of the Kansas City Cardiomyopathy Questionnaire: a new health status measure for heart failure. J Am Coll Cardiol. 2000;35:1245–55.
48. O’Carroll RE, Chambers JA, Dennis M, et al. Improving medication adherence in stroke survivors: mediators and moderators of treatment effects. Health Psychol. 2014;33:1241–50.
49. Bandura A. Social foundations of thought and action: a social cognitive theory. New Jersey: Prentice-Hall; 1986.
50. Murray MD, Morrow DG, Weiner M, et al. A conceptual framework to study medication adherence in older adults. Am J Geriatr Pharmacother. 2004;2:36–43.
51. Leventhal H, Zimmerman R, Gutmann M. Compliance: a self-regulation perspective. In: Gentry W, editor. Handbook of behavioural medicine. New York: Guilford Press; 1984. p. 53–176.
52. O’Carroll R, Dennis M, Johnston M, et al. Improving adherence to medication in stroke survivors (IAMSS): A randomised controlled trial: study protocol. BMC Neurol. 2010;10:358–68.
53. Hall PA, Fong GT. Temporal self-regulation theory: a model for individual health behavior. Health Psychol Rev. 2007;1:6–52.
54. Prochaska JO, DiClemente CC. Transtheoretical therapy: toward a more integrative model of change. Psychotherapy. 1982;19:276. doi:10.1037/h0088437.
55. Heather N, Rollnick S, Bell A, et al. Effects of brief counselling among male heavy drinkers identified on general hospital wards. Drug Alcohol Rev. 1996;15:29–38.
56. Miller WR. Motivational interviewing: research, practice, and puzzles. Addict Behav. 1996;21:835–42.
57. Williams AF, Manias E, Walker RG. The devil is in the detail-a multifactorial intervention to reduce blood pressure in co-existing diabetes and chronic kidney disease: a single blind, randomized controlled trial. BMC Fam Pract. 2010;11:3. doi:10.1186/1471-2296-11-3.
58. Rosenstock IM. Historical origins of the health belief model. Health Educ Behav. 1974;2:328–35.
59. Glanz K, Rimer BK, Viswanath K. Health behavior and health education: theory, research, and practice. San Francisco: Wiley; 2008.
60. Rosenstock IM, Strecher VJ, Becker MH. Social learning theory and the health belief model. Health Educ Behav. 1988;15:175–83.
61. van Dulmen S, Sluijs E, van Dijk L, et al. Patient adherence to medical treatment: a review of reviews. BMC Health Serv Res. 2007;7:55. doi:10.1186/1472-6963-7-55.
62. Conn VS, Hafdahl AR, Cooper PS, et al. Interventions to improve medication adherence among older adults: meta-analysis of adherence outcomes among randomized controlled trials. Gerontologist. 2009;49:447–62.
63. Holmes EAF, Hughes DA, Morrison VL. Predicting adherence to medications using health psychology theories: a systematic review of 20 years of empirical research. Value Health. 2014;17:863–76.
64. Arnet I, Abraham I, Messerli M, et al. A method for calculating adherence to polypharmacy from dispensing data records. Int J Clin Pharm. 2014;36:192–201.
65. Williamson PR, Altman DG, Blazeby JM, et al. Developing core outcome sets for clinical trials: issues to consider. Trials. 2012;13:1–8.
66. Arain M, Campbell MJ, Cooper CL, et al. What is a pilot or feasibility study? a review of current practice and editorial policy. BMC Med Res Methodol. 2010;10:1–7.
67. Thabane L, Ma J, Chu R, et al. A tutorial on pilot studies: the what, why and how. BMC Med Res Methodol. 2010;10:1. doi:10.1186/1471-2288-10-1.
68. Miller WR, Rollnick S. Motivational interviewing: helping people change. New York: Guilford Press; 2012.
69. Burke BL, Arkowitz H, Menchola M. The efficacy of motivational interviewing: a meta-analysis of controlled clinical trials. J Consult Clin Psychol. 2003;71:843–61.
70. Michie S, Johnston M, Abraham C, et al. Making psychological theory useful for implementing evidence based practice: a consensus approach. Qual Saf Health Care. 2005;14:26–33.
71. Cane J, O’Connor D, Michie S. Validation of the theoretical domains framework for use in behaviour change and implementation research. Implement Sci. 2012;7:37. doi:10.1186/1748-5908-7-37.
72. Fisher JD, Fisher WA. Theoretical approaches to individual-level change in HIV risk behavior. In: Peterson JL, DiClemente RJ, editors. Handbook of HIV prevention. New York: Kluwer Academic/Plenum; 2000. p. 3–55.
73. Michie S, Richardson M, Johnston M, et al. The behavior change technique taxonomy (v1) of 93 hierarchically clustered techniques: building an international consensus for the reporting of behavior change interventions. Ann Behav Med. 2013;46:81–95.
74. Cane J, Richardson M, Johnston M, et al. From lists of behaviour change techniques (BCTs) to structured hierarchies: comparison of two methods of developing a hierarchy of BCTs. Br J Health Psychol. 2015;20:130–50.
75. Hughes CM, Cadogan CA, Ryan CA. Development of a pharmacy practice intervention: lessons from the literature. Int J Clin Pharm. 2015:1–6. doi:10.1007/s11096-015-0180-6.
76. Eliasson L, Barber N, Weinman J. Applying COM-B to medication adherence. Eur Health Psychol. 2011;16:7–17.
77. Lopez LM, Tolley EE, Grimes DA, et al. Theory-based interventions for contraception. Cochrane Database Syst Rev. 2011;(3):CD007249. doi:10.1002/14651858.CD007249.pub3.
78. Gourlan M, Bernard P, Bortolon C, et al. Efficacy of theory-based interventions to promote physical activity. A meta-analysis of randomised controlled trials. Health. Psychol Rev. 2015;10:1–17.
79. Colquhoun HL, Brehaut JC, Sales A, et al. A systematic review of the use of theory in randomized controlled trials of audit and feedback. Implement Sci. 2013;8:66. doi:10.1186/1748-5908-8-66.
80. George J, Elliott RA, Stewart DC. A systematic review of interventions to improve medication taking in elderly patients prescribed multiple medications. Drugs Aging. 2008;25:307–24.
81. Albrecht L, Archibald M, Arseneau D, et al. Development of a checklist to assess the quality of reporting of knowledge translation interventions using the Workgroup for Intervention Development and Evaluation Research (WIDER) recommendations. Implement Sci. 2013;8:52. doi:10.1186/1748-5908-8-52.
82. Stewart D, Klein S. The use of theory in research. Int J Clin Pharm. 2016;38(3):615–9. doi:10.1007/s11096-015-0216-y.
83. Thompson K, Kulkarni J, Sergejew AA. Reliability and validity of a new Medication Adherence Rating Scale (MARS) for the psychoses. Schizophr Res. 2000;42:241–7.