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Volumn 21, Issue 6, 1999, Pages 1074-1090

Methods for measuring and monitoring medication regimen adherence in clinical trials and clinical practice

Author keywords

Adherence; Compliance; Measurement; Medication use; Monitoring device

Indexed keywords

DRUG;

EID: 0032796185     PISSN: 01492918     EISSN: 1879114X     Source Type: Journal    
DOI: 10.1016/S0149-2918(99)80026-5     Document Type: Article
Times cited : (705)

References (61)
  • 2
    • 0000522719 scopus 로고
    • A critical review of interventions to improve compliance with prescribed medications
    • 2. Haynes RB, Wang E, Da Mota Gomes M. A critical review of interventions to improve compliance with prescribed medications. Patient Educ Couns. 1987;10:155-166.
    • (1987) Patient Educ Couns , vol.10 , pp. 155-166
    • Haynes, R.B.1    Wang, E.2    Da Mota Gomes, M.3
  • 3
    • 0030578667 scopus 로고    scopus 로고
    • Systematic review of randomised trials of interventions to assist patients to follow prescriptions for medications
    • 3. Haynes RB, McKibbon KA, Kanani R. Systematic review of randomised trials of interventions to assist patients to follow prescriptions for medications. Lancet. 1996;348:383-386.
    • (1996) Lancet , vol.348 , pp. 383-386
    • Haynes, R.B.1    McKibbon, K.A.2    Kanani, R.3
  • 4
    • 0021241325 scopus 로고
    • Overview of patient compliance with medication dosing: A literature review
    • 4. Greenberg RN. Overview of patient compliance with medication dosing: A literature review. Clin Ther. 1984;6:592-599.
    • (1984) Clin Ther , vol.6 , pp. 592-599
    • Greenberg, R.N.1
  • 6
    • 0031852553 scopus 로고    scopus 로고
    • Pill count, self-report, and pharmacy claims data to measure medication adherence in the elderly
    • 6. Grymonpre RE, Didur CD, Montgomery PR, Sitar DS. Pill count, self-report, and pharmacy claims data to measure medication adherence in the elderly. Ann Pharmacother. 1998;32:749-754.
    • (1998) Ann Pharmacother , vol.32 , pp. 749-754
    • Grymonpre, R.E.1    Didur, C.D.2    Montgomery, P.R.3    Sitar, D.S.4
  • 7
    • 0027383632 scopus 로고
    • Non-compliance - Or how many aunts has Matilda?
    • 7. Wright EC. Non-compliance - or how many aunts has Matilda? Lancet. 1993; 342:909-913.
    • (1993) Lancet , vol.342 , pp. 909-913
    • Wright, E.C.1
  • 8
    • 0003976846 scopus 로고
    • Statistical approach to subgroup analyses: Patient compliance data and clinical outcomes
    • Cramer JA, Spilker B, eds. New York: Raven Press
    • 8. Hurley FL. Statistical approach to subgroup analyses: Patient compliance data and clinical outcomes. In: Cramer JA, Spilker B, eds. Patient Compliance in Medical Practice and Clinical Trials. New York: Raven Press; 1991:243-250.
    • (1991) Patient Compliance in Medical Practice and Clinical Trials , pp. 243-250
    • Hurley, F.L.1
  • 9
    • 0027293786 scopus 로고
    • The relationship of treatment adherence to the risk of death after myocardial infarction in women
    • 9. Gallagher EJ, Viscoli CM, Horwitz RI. The relationship of treatment adherence to the risk of death after myocardial infarction in women. JAMA. 1993;270:742-744.
    • (1993) JAMA , vol.270 , pp. 742-744
    • Gallagher, E.J.1    Viscoli, C.M.2    Horwitz, R.I.3
  • 10
    • 0002983646 scopus 로고
    • Biometric issues in measuring and analyzing partial compliance in clinical trials
    • Cramer JA, Spilker B, eds. New York: Raven Press
    • 10. Hasford J. Biometric issues in measuring and analyzing partial compliance in clinical trials. In: Cramer JA, Spilker B, eds. Patient Compliance in Medical Practice and Clinical Trials. New York: Raven Press; 1991:265-282.
    • (1991) Patient Compliance in Medical Practice and Clinical Trials , pp. 265-282
    • Hasford, J.1
  • 11
    • 0000184866 scopus 로고
    • Oral contraceptive compliance and its role in the effectiveness of the method
    • Cramer JA, Spilker B, eds. New York: Raven Press
    • 11. Potter LS. Oral contraceptive compliance and its role in the effectiveness of the method. In: Cramer JA, Spilker B, eds. Patient Compliance in Medical Practice and Clinical Trials. New York: Raven Press; 1991:195-207.
    • (1991) Patient Compliance in Medical Practice and Clinical Trials , pp. 195-207
    • Potter, L.S.1
  • 12
    • 0028967825 scopus 로고
    • Discontinuation of antihyperlipidemic drugs - Do rates reported in clinical trials reflect rates in primary care settings?
    • 12. Andrade SE, Walker AM, Gottlieb LK, et al. Discontinuation of antihyperlipidemic drugs - do rates reported in clinical trials reflect rates in primary care settings? NEJM. 1995;332:1125-1131.
    • (1995) NEJM , vol.332 , pp. 1125-1131
    • Andrade, S.E.1    Walker, A.M.2    Gottlieb, L.K.3
  • 13
    • 0009618143 scopus 로고    scopus 로고
    • Compliance in clinical trials
    • 13. Gibaldi M. Compliance in clinical trials. Pharmaceutical News. 1996;3:16-18.
    • (1996) Pharmaceutical News , vol.3 , pp. 16-18
    • Gibaldi, M.1
  • 14
    • 0025598872 scopus 로고
    • The run-in period in clinical trials: The effect of misclassification on efficiency
    • 14. Brittain E, Wittes J. The run-in period in clinical trials: The effect of misclassification on efficiency. Control Clin Trials. 1990;11:327-338.
    • (1990) Control Clin Trials , vol.11 , pp. 327-338
    • Brittain, E.1    Wittes, J.2
  • 15
    • 0003134229 scopus 로고
    • Monitoring compliance with antiepileptic drug therapy
    • Cramer JA, Spilker B, eds. New York: Raven Press
    • 15. Cramer JA, Maltson RH. Monitoring compliance with antiepileptic drug therapy. In: Cramer JA, Spilker B, eds. Patient Compliance in Medical Practice and Clinical Trials. New York: Raven Press; 1991: 123-137.
    • (1991) Patient Compliance in Medical Practice and Clinical Trials , pp. 123-137
    • Cramer, J.A.1    Maltson, R.H.2
  • 16
    • 0018178436 scopus 로고
    • Problems of spectrum and bias in evaluating the efficacy of diagnostic tests
    • 16. Ransohoff DF, Feinstein AR. Problems of spectrum and bias in evaluating the efficacy of diagnostic tests. NEJM. 1978; 299:926-930.
    • (1978) NEJM , vol.299 , pp. 926-930
    • Ransohoff, D.F.1    Feinstein, A.R.2
  • 17
    • 0019179998 scopus 로고
    • Can simple clinical measurements detect patient noncompliance?
    • 17. Haynes RB, Taylor DW, Sackett DL, et al. Can simple clinical measurements detect patient noncompliance? Hypertension. 1980;2:757-764.
    • (1980) Hypertension , vol.2 , pp. 757-764
    • Haynes, R.B.1    Taylor, D.W.2    Sackett, D.L.3
  • 18
    • 0027995478 scopus 로고
    • Critical comparison of novel and existing methods of compliance assessment during a clinical trial of an oral iron chelator
    • 18. Matsui D, Hermann C, Klein JJ, et al. Critical comparison of novel and existing methods of compliance assessment during a clinical trial of an oral iron chelator. J Clin Pharmacol. 1994;34:944-949.
    • (1994) J Clin Pharmacol , vol.34 , pp. 944-949
    • Matsui, D.1    Hermann, C.2    Klein, J.J.3
  • 19
    • 0022033796 scopus 로고
    • Accuracy of indirect measures of medication compliance in hypertension
    • 19. Craig HM. Accuracy of indirect measures of medication compliance in hypertension. Res Nurs Health. 1985;8:61-66.
    • (1985) Res Nurs Health , vol.8 , pp. 61-66
    • Craig, H.M.1
  • 20
    • 0025015490 scopus 로고
    • Reporting compliance in clinical trials
    • Letter
    • 20. Pullar T, Feely MP. Reporting compliance in clinical trials. Lancet. 1990;336:1252-1253. Letter.
    • (1990) Lancet , vol.336 , pp. 1252-1253
    • Pullar, T.1    Feely, M.P.2
  • 22
    • 0031408466 scopus 로고    scopus 로고
    • Measurement of non-compliance to antihypertensive medication using pill counts and pharmacy records
    • 22. Gregoire J-P, Guilbert R, Archambault A, Contandriopoulos A-P. Measurement of non-compliance to antihypertensive medication using pill counts and pharmacy records. J Soc Adm Pharm. 1998;14:198-207.
    • (1998) J Soc Adm Pharm , vol.14 , pp. 198-207
    • Gregoire, J.-P.1    Guilbert, R.2    Archambault, A.3    Contandriopoulos, A.-P.4
  • 23
    • 0025338414 scopus 로고
    • On white-coat effects and the electronic monitoring of compliance
    • 23. Feinstein AR. On white-coat effects and the electronic monitoring of compliance. Arch Intern Med. 1990;150:1377-1378.
    • (1990) Arch Intern Med , vol.150 , pp. 1377-1378
    • Feinstein, A.R.1
  • 25
    • 0020117387 scopus 로고
    • Nondichotomous patterns of medication usage: The yes-no fallacy
    • 25. Dirks JF, Kinsman R. Nondichotomous patterns of medication usage: The yes-no fallacy. Clin Pharmacol Ther. 1982;31:413-417.
    • (1982) Clin Pharmacol Ther , vol.31 , pp. 413-417
    • Dirks, J.F.1    Kinsman, R.2
  • 26
    • 0031017179 scopus 로고    scopus 로고
    • Patient self-reporting of compliance does not correspond with electronic monitoring: An evaluation using isosorbide dinitrate as a model drug
    • 26. Straka RJ, Fish JT, Benson SR, Suh JT. Patient self-reporting of compliance does not correspond with electronic monitoring: An evaluation using isosorbide dinitrate as a model drug. Pharmacotherapy. 1997;17:126-132.
    • (1997) Pharmacotherapy , vol.17 , pp. 126-132
    • Straka, R.J.1    Fish, J.T.2    Benson, S.R.3    Suh, J.T.4
  • 27
    • 0001174053 scopus 로고
    • A comparison of patient dosage deviation reports with pill counts
    • 27. Park LC, Lipman RS. A comparison of patient dosage deviation reports with pill counts. Psychopharmacologia. 1964;6:299-302.
    • (1964) Psychopharmacologia , vol.6 , pp. 299-302
    • Park, L.C.1    Lipman, R.S.2
  • 28
    • 0019773965 scopus 로고
    • Screening for noncompliance among patients with hypertension: Is self-report the best available measure?
    • 28. Inui TS, Carter WB, Pecoraro RE. Screening for noncompliance among patients with hypertension: Is self-report the best available measure? Med Care. 1981;19:1061-1064.
    • (1981) Med Care , vol.19 , pp. 1061-1064
    • Inui, T.S.1    Carter, W.B.2    Pecoraro, R.E.3
  • 29
    • 0014454724 scopus 로고
    • The inaccuracy in using interviews to estimate patient reliability in taking medications at home
    • 29. Gordis L, Markowitz M, Lilienfeld AM. The inaccuracy in using interviews to estimate patient reliability in taking medications at home. Med Care. 1969;7:49-54.
    • (1969) Med Care , vol.7 , pp. 49-54
    • Gordis, L.1    Markowitz, M.2    Lilienfeld, A.M.3
  • 30
    • 0022632510 scopus 로고
    • Concurrent and predictive validity of a self-reported measure of medication adherence
    • 30. Morisky DE, Green LW, Levine DM. Concurrent and predictive validity of a self-reported measure of medication adherence. Med Care. 1986;24:67-74.
    • (1986) Med Care , vol.24 , pp. 67-74
    • Morisky, D.E.1    Green, L.W.2    Levine, D.M.3
  • 31
    • 0026536664 scopus 로고
    • Out-patient compliance with antidepressant medication
    • 31. Myers ED, Branthwaite A. Out-patient compliance with antidepressant medication. Br J Psychiatry. 1992;160:83-86.
    • (1992) Br J Psychiatry , vol.160 , pp. 83-86
    • Myers, E.D.1    Branthwaite, A.2
  • 32
    • 0024334284 scopus 로고
    • Studies of doctor-patient interaction
    • 32. Roter DL, Hall JA. Studies of doctor-patient interaction. Ann Rev Public Health. 1989;10:163-180.
    • (1989) Ann Rev Public Health , vol.10 , pp. 163-180
    • Roter, D.L.1    Hall, J.A.2
  • 33
    • 0014250577 scopus 로고
    • Variations in patients' compliance with doctors' advice: An empirical analysis of patterns of communication
    • 33. Davis M. Variations in patients' compliance with doctors' advice: An empirical analysis of patterns of communication. Am J Public Health. 1969;58:274-288.
    • (1969) Am J Public Health , vol.58 , pp. 274-288
    • Davis, M.1
  • 34
    • 0026074601 scopus 로고
    • Patient compliance - Whose responsibility?
    • 34. Ross FM. Patient compliance - whose responsibility? Soc Sci Med. 1991;32:89-94.
    • (1991) Soc Sci Med , vol.32 , pp. 89-94
    • Ross, F.M.1
  • 35
    • 0026462876 scopus 로고
    • Antecedents of adherence to medical recommendations: Results from the medical outcomes study
    • 35. Sherbourne CD, Hays RD, Ordway L, et al. Antecedents of adherence to medical recommendations: Results from the Medical Outcomes Study. J Behav Med. 1992; 15:447-468.
    • (1992) J Behav Med , vol.15 , pp. 447-468
    • Sherbourne, C.D.1    Hays, R.D.2    Ordway, L.3
  • 36
    • 0023250566 scopus 로고
    • The validity of an interview to assess a patient's drug taking
    • 36. Stewart M. The validity of an interview to assess a patient's drug taking. Am J Prev Med. 1987;3:95-100.
    • (1987) Am J Prev Med , vol.3 , pp. 95-100
    • Stewart, M.1
  • 37
    • 0027336393 scopus 로고
    • When tuberculosis treatment fails: A social behavioral account of patient adherence
    • 37. Sumartojo E. When tuberculosis treatment fails: A social behavioral account of patient adherence. Am Rev Respir Dis. 1993;147:1311-1320.
    • (1993) Am Rev Respir Dis , vol.147 , pp. 1311-1320
    • Sumartojo, E.1
  • 38
    • 85030352351 scopus 로고    scopus 로고
    • The Brief Medication Questionnaire: A tool for screening patient adherence and barriers to adherence
    • In press
    • 38. Svarstad BL, Chewning BA, Sleath BL, Claesson C. The Brief Medication Questionnaire: A tool for screening patient adherence and barriers to adherence. Patient Educ Couns. In press.
    • Patient Educ Couns
    • Svarstad, B.L.1    Chewning, B.A.2    Sleath, B.L.3    Claesson, C.4
  • 39
    • 0002450733 scopus 로고
    • Methods of assessing and improving patient compliance in clinical trials
    • Cramer JA, Spilker B, eds. New York: Raven Press
    • 39. Spilker B. Methods of assessing and improving patient compliance in clinical trials. In: Cramer JA, Spilker B, eds. Patient Compliance in Medical Practice and Clinical Trials. New York: Raven Press; 1991:37-56.
    • (1991) Patient Compliance in Medical Practice and Clinical Trials , pp. 37-56
    • Spilker, B.1
  • 40
    • 0026452421 scopus 로고
    • Metered-dose inhaler adherence in a clinical trial
    • 40. Rand CS, Wise RA, Nides MA, et al. Metered-dose inhaler adherence in a clinical trial. Am Rev Respir Dis. 1992;146:1559-1564.
    • (1992) Am Rev Respir Dis , vol.146 , pp. 1559-1564
    • Rand, C.S.1    Wise, R.A.2    Nides, M.A.3
  • 41
    • 0024343414 scopus 로고
    • How often is medication taken as prescribed? A novel assessment technique
    • 41. Cramer JA, Mattson RH, Prevey ML, et al. How often is medication taken as prescribed? A novel assessment technique. JAMA. 1989;261:3273-3277.
    • (1989) JAMA , vol.261 , pp. 3273-3277
    • Cramer, J.A.1    Mattson, R.H.2    Prevey, M.L.3
  • 42
    • 0031046049 scopus 로고    scopus 로고
    • The assessment of refill compliance using pharmacy records: Methods, validity, and applications
    • 42. Steiner JF, Prochazka AV. The assessment of refill compliance using pharmacy records: Methods, validity, and applications. J Clin Epidemiol. 1997;50:105-116.
    • (1997) J Clin Epidemiol , vol.50 , pp. 105-116
    • Steiner, J.F.1    Prochazka, A.V.2
  • 43
    • 0025878821 scopus 로고
    • An evaluative study of unclaimed prescriptions
    • 43. Craghead RM, Wartski DM, An evaluative study of unclaimed prescriptions. Hosp Pharm . 1991;26:616-617.
    • (1991) Hosp Pharm , vol.26 , pp. 616-617
    • Craghead, R.M.1    Wartski, D.M.2
  • 44
    • 0024499928 scopus 로고
    • Effect of automated prescription transmittal on number of unclaimed prescriptions
    • 44. Craghead RM, Wartski DM. Effect of automated prescription transmittal on number of unclaimed prescriptions. Am J Hosp Pharm. 1989;46:310-312.
    • (1989) Am J Hosp Pharm , vol.46 , pp. 310-312
    • Craghead, R.M.1    Wartski, D.M.2
  • 45
    • 0024060815 scopus 로고
    • A general method of compliance assessment using centralized pharmacy records
    • 45. Steiner JF, Kocpsell TD, Fihn SD, Inui TS. A general method of compliance assessment using centralized pharmacy records. Med Care. 1988;26:814-823.
    • (1988) Med Care , vol.26 , pp. 814-823
    • Steiner, J.F.1    Kocpsell, T.D.2    Fihn, S.D.3    Inui, T.S.4
  • 46
    • 0026773650 scopus 로고
    • Use of prescription-refill records to assess patient compliance
    • 46. Hamilton RA, Briceland LL. Use of prescription-refill records to assess patient compliance. Am J Hosp Pharm. 1992;49: 1691-1696.
    • (1992) Am J Hosp Pharm , vol.49 , pp. 1691-1696
    • Hamilton, R.A.1    Briceland, L.L.2
  • 47
    • 0027233773 scopus 로고
    • Treatment for glaucoma: Adherence by the elderly
    • 47. Gurwitz JH, Glynn RJ, Monane M, et al. Treatment for glaucoma: Adherence by the elderly. Am J Public Health. 1993;83:711-716.
    • (1993) Am J Public Health , vol.83 , pp. 711-716
    • Gurwitz, J.H.1    Glynn, R.J.2    Monane, M.3
  • 48
    • 0031279418 scopus 로고    scopus 로고
    • Assessing compliance to antihypertensive medications using computer-based pharmacy records
    • 48. Christensen DB, Williams B, Goldberg HI, et al. Assessing compliance to antihypertensive medications using computer-based pharmacy records. Med Care. 1997;35:1164-1170.
    • (1997) Med Care , vol.35 , pp. 1164-1170
    • Christensen, D.B.1    Williams, B.2    Goldberg, H.I.3
  • 49
    • 0028148312 scopus 로고
    • Long-term patient compliance with prescribed regimens of calcium channel blockers
    • 49. Farmer KC, Jacobs EW, Phillips CR. Long-term patient compliance with prescribed regimens of calcium channel blockers. Clin Ther. 1994;16:316-326.
    • (1994) Clin Ther , vol.16 , pp. 316-326
    • Farmer, K.C.1    Jacobs, E.W.2    Phillips, C.R.3
  • 50
    • 0025775670 scopus 로고
    • Effectiveness of the C cap in promoting prescription refill compliance among patients with glaucoma
    • 50. Sclar DA, Skaer TL, Okamoto MP, Gill MA. Effectiveness of the C Cap in promoting prescription refill compliance among patients with glaucoma. Clin Ther. 1991;13:396-400.
    • (1991) Clin Ther , vol.13 , pp. 396-400
    • Sclar, D.A.1    Skaer, T.L.2    Okamoto, M.P.3    Gill, M.A.4
  • 51
    • 0027373853 scopus 로고
    • Effect of value-added utilities on prescription refill compliance and health care expenditures for hypertension
    • 51. Skaer TL, Sclar DA, Markowski DJ, Won JK. Effect of value-added utilities on prescription refill compliance and health care expenditures for hypertension. J Hum Hypertens. 1993;7:515-518.
    • (1993) J Hum Hypertens , vol.7 , pp. 515-518
    • Skaer, T.L.1    Sclar, D.A.2    Markowski, D.J.3    Won, J.K.4
  • 52
    • 0028084950 scopus 로고
    • Examination of days supply in computerized prescription claims
    • 52. Farris KB, Kaplan B, Kirking DM. Examination of days supply in computerized prescription claims. J Pharmacoepidemiol. 1994;3:63-76.
    • (1994) J Pharmacoepidemiol , vol.3 , pp. 63-76
    • Farris, K.B.1    Kaplan, B.2    Kirking, D.M.3
  • 53
    • 0030136577 scopus 로고    scopus 로고
    • Adherence to single daily dose of aspirin in a chemoprevention trial. An evaluation of self-report and microelectronic monitoring
    • 53. Burney KD, Krishnan K, Ruffin MT, et al. Adherence to single daily dose of aspirin in a chemoprevention trial. An evaluation of self-report and microelectronic monitoring. Arch Fam Med. 1996;5:297-300.
    • (1996) Arch Fam Med , vol.5 , pp. 297-300
    • Burney, K.D.1    Krishnan, K.2    Ruffin, M.T.3
  • 54
    • 0025499436 scopus 로고
    • The effects of monitoring and feedback on compliance
    • 54. Elixhauser A, Eisen SA, Romeis JC, Homan SM. The effects of monitoring and feedback on compliance. Med Care. 1990; 28:882-893.
    • (1990) Med Care , vol.28 , pp. 882-893
    • Elixhauser, A.1    Eisen, S.A.2    Romeis, J.C.3    Homan, S.M.4
  • 56
    • 0027733686 scopus 로고
    • Patient adherence to prescribed potassium supplement therapy
    • 56. Halpern MT, Irwin DE, Brown RE, et al. Patient adherence to prescribed potassium supplement therapy. Clin Ther. 1993;15: 1133-1145.
    • (1993) Clin Ther , vol.15 , pp. 1133-1145
    • Halpern, M.T.1    Irwin, D.E.2    Brown, R.E.3
  • 58
    • 0018596561 scopus 로고
    • Measurement of medication compliance in a clinical setting. Comparison of three methods in patients prescribed digoxin
    • 58. Fletcher SW, Pappius EM, Harper SJ. Measurement of medication compliance in a clinical setting. Comparison of three methods in patients prescribed digoxin. Arch Intern Med. 1979;139:635-638.
    • (1979) Arch Intern Med , vol.139 , pp. 635-638
    • Fletcher, S.W.1    Pappius, E.M.2    Harper, S.J.3
  • 59
    • 0022639356 scopus 로고
    • Compliance of patients with asthma with an experimental aerosolized medication: Implications for controlled clinical trials
    • 59. Spector SL, Kinsman R, Mawhinney H, et al. Compliance of patients with asthma with an experimental aerosolized medication: Implications for controlled clinical trials. J Allergy Clin Immunol. 1986;77:65-70.
    • (1986) J Allergy Clin Immunol , vol.77 , pp. 65-70
    • Spector, S.L.1    Kinsman, R.2    Mawhinney, H.3
  • 60
    • 0018577067 scopus 로고
    • In search of the gold standard for compliance measurement
    • 60. Rudd P. In search of the gold standard for compliance measurement. Arch Intern Med. 1979;139:627-628.
    • (1979) Arch Intern Med , vol.139 , pp. 627-628
    • Rudd, P.1
  • 61
    • 0009615113 scopus 로고    scopus 로고
    • Federal Regulation 21 Part 312.56. Washington, DC: US Department of Health and Human Services, Food and Drug Administration
    • 61. FDA Center for Drug Evaluation and Research. Guidance for Industry: General Considerations for the Clinical Evaluation of Drugs. Federal Regulation 21 Part 312.56. Washington, DC: US Department of Health and Human Services, Food and Drug Administration, 1997.
    • (1997) Guidance for Industry: General Considerations for the Clinical Evaluation of Drugs


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