A conceptual framework to study medication adherence in older adults

American Journal Geriatric Pharmacotherapy

Volumn 2, Issue 1, 2004, Pages 36-43

  Murray, Michael D ^a,b,c   Morrow, Daniel G ^d   Weiner, Michael ^b,c   Clark, Daniel O ^b,c   Tu, Wanzhu ^b,c   Deer, Melissa M ^c   Brater, D Craig ^b   Weinberger, Morris ^e  

^a PURDUE UNIVERSITY   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c REGENSTRIEF INSTITUTE   (United States)

^d UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^e UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Aged; Conceptual model; Medication adherence; Outcomes research

Indexed keywords

CARDIOVASCULAR AGENT; HERBACEOUS AGENT;

ADULT; AGE; AGED; AGING; COGNITION; CONGESTIVE HEART FAILURE; DRUG MONITORING; DRUG USE; ELDERLY CARE; ENVIRONMENTAL FACTOR; FINANCIAL MANAGEMENT; HEALTH CARE QUALITY; HEALTH CARE SYSTEM; HEARING; HEART FAILURE; HUMAN; INTERPERSONAL COMMUNICATION; MEDICAL LITERATURE; MEDICAL RESEARCH; MEDLINE; MODEL; OUTCOMES RESEARCH; PATIENT COMPLIANCE; PATIENT EDUCATION; PATIENT INFORMATION; PHARMACEUTICAL CARE; PHARMACIST; PHYSICAL DISABILITY; PRESCRIPTION; PRIORITY JOURNAL; READING; REVIEW; SOCIAL ASPECT; VISION;

EID: 2342422601     PISSN: 15435946     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1543-5946(04)90005-0     Document Type: Article

References (69)

1. Murray MD, Callahan CM. Improving medication use for older adults: An integrated research agenda. Ann Intern Med. 2003;139:425-429.
2. Murray MD, Darnell J, Weinberger M, Martz BL. Factors contributing to medication noncompliance in elderly public housing tenants. Drug Intell Clin Pharm. 1986;120:146-152.
3. Murray MD, Young JM, Morrow DG, et al. Methodology of an ongoing, randomized, controlled trial to improve drug use for elderly patients with chronic heart failure. Am J Geriatr Pharmacother. 2004;2: 53-65.
4. Haynes RB. Helping patients follow the treatments you prescribe. In: Sackett DL, Haynes RB, Guyatt GH, Tugwell P, eds. Clinical Epidemiology: A Basic Science for Clinical Medicine. 2nd ed. Boston, Mass: Little, Brown; 1991:249-281.
5. Miller NH, Hill M, Kottke T, Ockene IS. The multilevel compliance challenge: Recommendations for a call to action. A statement for healthcare professionals. Circulation. 1997;95:1085-1090.
6. Hill MN, Miller NH. Compliance enhancement. A call for multidisciplinary team approaches. Circulation. 1996; 93:4-6.
7. Haynes RB, Montague P, Oliver T, et al. Interventions for helping patients to follow prescriptions for medications. Cochrane Database Syst Rep. 2000;CD000011.
8. McDonald HP, Garg AX, Haynes KB. Interventions to enhance patient adherence to medication prescriptions: Scientific review. JAMA. 2002;288:2868-2879.
9. Interventions to Improve Adherence to Medical Regimens in the Elderly. Washington, DC: Center for the Advancement of Health; 1999.
10. Haynes RB, McDonald HP, Garg AX. Helping patients follow prescribed treatment: Clinical applications. JAMA. 2002;288:2880-2883.
11. Park DC, Jones TR. Medication adherence and aging. In: Fisk AD, Rogers WA, eds. Handbook of Human Factors and the Older Adult. San Diego, Calif: Academic Press; 1997:257-287.
12. Stephenson BJ, Rowe BH, Haynes RB, et al. The rational clinical examination. Is this patient taking the treatment as prescribed? JAMA. 1993;269:2779-2781.
13. Rudd P, Byyny RL, Zachary V, et al. The natural history of medication compliance in a drug trial: Limitations of pill counts. Clin Pharmacol Ther. 1989;46:169-176.
14. Steiner JF, Prochazka AV. The assessment of refill compliance using pharmacy records: Methods, validity, and applications. J Clin Epidemiol. 1997;50:105-116.
15. Monane M, Bohn RL, Gurwitz JH, et al. Non-compliance with congestive heart failure therapy in the elderly. Arch Intern Med. 1994;154:433-437.
16. Cramer JA, Mattson RH, Prevey ML, et al. How often is medication taken as prescribed? A novel assessment technique. JAMA. 1989;261:3273-3277.
17. Cramer JA. Microelectronic systems for monitoring and enhancing patient compliance with medication regimens. Drugs. 1995;149:321-327.
18. Morrell RW, Park DC, Kidder DP, Martin M. Adherence to antihypertensive medications across the life span. Gerontologist. 1997;37:609-619.
19. Bibliography: Peer-reviewed papers. AARDEX Web site. Available at: http://www.aardex.ch/BibliographyPeer.htm. Accessed February 5, 2004.
20. Weintraub M. Compliance in the elderly. Clin Geriatr Med. 1990;6:445-452.
21. Darnell JC, Murray MD, Martz BL, Weinberger M. Medication use by ambulatory elderly. An in-home survey. J Am Geriatr Soc. 1986;34:1-4.
22. Johnson RE, Ried LD. OTC drug use in an HMO: Comparing the elderly and younger adults. J Aging Health. 1996;8:114-135.
23. Mashour NH, Lin GI, Frishman WH. Herbal medicine for the treatment of cardiovascular disease: Clinical considerations. Arch Intern Med. 1998;158:2225-2234.
24. Gattis WA, Hasselblad V, Whellan DJ, O'Connor CM. Reduction in heart failure events by the addition of a clinical pharmacist to the heart failure management team: Results of the Pharmacist in Heart Failure Assessment Recommendation and Monitoring (PHARM) Study. Arch Intern Med. 1999;159:1939-1945.
25. Varma S, McElnay JC, Hughes CM, et al. Pharmaceutical care of patients with congestive heart failure: Interventions and outcomes. Pharmacotherapy. 1999;19: 860-869.
26. Goodyer LI, Miskelly F, Milligan P. Does encouraging good compliance improve patients' clinical condition in heart failure? Br J Clin Pract. 1995;49:173-176.
27. Chobanian AV, Bakris GL, Black HR, et al. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: The JNC 7 report [published correction appears in JAMA. 2003;290:197]. JAMA. 2003;289: 2560-2572.
28. Gryfe CI, Gryfe BM. Drug therapy of the aged: The problem of compliance and the roles of physicians and pharmacists. J Am Geriatr Soc. 1984;32:301-307.
29. Rogers WA. Individual differences, aging, and human factors: An overview. In: Fisk AD, Rogers WA, eds. Handbook of Human Factors and the Older Adult. San Diego, Calif: Academic Press; 1997:151-170.
30. Bero LA, Mays NB, Barjesteh K, Bond C. Expanding the roles of outpatient pharmacists: Effects on health services utilisation, costs, and patient outcomes. Cochrane Database Syst Rep. 2000;CD000336.
31. Opdycke RA, Ascione FJ, Shimp LA, Rosen RI. A systematic approach to educating elderly patients about their medications. Patient Educ Couns. 1992;19:43-60.
32. Bogden PE, Koontz LM, Williamson P, Abbott RD. The physician and pharmacist team. An effective approach to cholesterol reduction. J Gen Intern Med. 1997;12:158-164.
33. Lipton HL, Bird JA. The impact of clinical pharmacists' consultations on geriatric patients' compliance and medical care use: A randomized controlled trial. Gerontologist. 1994;34:307-315.
34. Lipton HL. Prescription drugs and the elderly. Strategies for effective drug prescribing and use. Mobius. 1984;4: 145-155.
35. Murray MD, Birt JA, Manatunga AK, Darnell JC. Medication compliance in elderly outpatients using twice-daily dosing and unit-of-use packaging. Ann Pharmacother. 1993;27:616-621.
36. Stuck AE, Tamai IY. Medication management in the home. Clin Geriatr Med. 1991;7:733-748.
37. Ghali JK, Kadakia S, Cooper R, Ferlinz J. Precipitating factors leading to decompensation of heart failure. Traits among urban blacks. Arch Intern Med. 1988;148:2013-2016.
38. Shaw SM, Opit LJ. Need for supervision in the elderly receiving long-term prescribed medication. BMJ. 1976;1: 505-507.
39. Shane R, Gouveia WA. Developing a strategic plan for quality in pharmacy practice. Am J Health Syst Pharm. 2000;57:470-474.
40. Shane R. The health care puzzle: Where does pharmacy fit? Am J Health Syst Pharm. 1997;54:2503-2505.
41. Hurd PD, Butkovich SL. Compliance problems and the older patient: Assessing functional limitations. Drug Intell Clin Pharm. 1986;20:228-231.
42. Morrow D, Leirer V, Sheikh J. Adherence and medication instructions: Review and recommendations. J Am Geriatr Soc. 1988;36:1147-1160.
43. Gazmararian JA, Baker DW, Williams MV, et al. Health literacy among Medicare enrollees in a managed care organization. JAMA. 1999;281:545-551.
44. Gruneberg MM, Morris PE, Sykes RN, eds. Practical Aspects of Memory. London, UK: Academic Press; 1978.
45. Park DC, Hertzog C, Leventhal H, et al. Medication adherence in rheumatoid arthritis patients: Older is wiser. J Am Geriatr Soc. 1999;47:172-183.
46. Morrow D, Leirer V. Designing medication instructions for older adults. In: Park DC, Morrell RW, Shifren K, eds. Processing of Medical Information in Aging Patients: Cognitive and Human Factors Perspectives. Mahwah, NJ: Lawrence Erlbaum; 1999:249-265.
47. Phillips KA, Morrison KR, Anderson R, Aday LA. Understanding the context of healthcare utilization: Assessing environmental and provider-related variables in the behavioral model of utilization. Health Serv Res. 1998;33:571-596.
48. Kline D, Scialfa C. Sensory and perceptual functioning: Basic research and human factors implications. In: Fisk AD, Rogers WA, eds. Handbook of Human Factors and the Older Adult. San Diego, Calif. Academic Press; 1997:27-54.
49. Isaac LM, Tamblyn RM. Compliance and cognitive function: A methodological approach to measuring unintentional errors in medication compliance in the elderly. McGill-Calgary Drug Research Team. Gerontologist. 1993;33:772-781.
50. Conn V, Taylor S, Miller R. Cognitive impairment and medication adherence. J Gerontol Nurs. 1994;120:41-47.
51. Fitten LJ, Coleman L, Siembieda DW, et al. Assessment of capacity to comply with medication regimens in older patients. J Am Geriatr Soc. 1995;43:361-367.
52. Ruscin JM, Semla TP. Assessment of medication management skills in older outpatients. Ann Pharmacother. 1996;30:1083-1088.
53. Heckbert SR, Longstreth WT Jr, Psaty BM, et al. The association of antihypertensive agents with MRI white matter findings and with Modified Mini-Mental State Examination in older adults. J Am Geriatr Soc. 1997; 45:1423-1433.
54. Zuccalá G, Cattel C, Manes-Gravina E, et al. Left ventricular dysfunction: A clue to cognitive impairment in older patients with heart failure. J Neurol Neurosurg Psychiatry. 1997;63:509-512.
55. Proctor EK, Morrow-Howell N, Chadiha L, et al. Physical and cognitive functioning among chronically ill African-American and white elderly in home care following hospital discharge. Med Care. 1997;35:782-791.
56. Health literacy: Report of the Council on Scientific Affairs. Ad Hoc Committee on Health Literacy for the Council on Scientific Affairs, American Medical Association. JAMA. 1999;281:552-557.
57. Baker DW, Gazmararian JA, Sudano J, Patterson M. The association between age and health literacy among elderly persons. J Gerontol B. 2000;55:S368-S374.
58. Baker DW, Parker RM, Williams MV, Clark WS. Health literacy and the risk of hospital admission. J Gen Intern Med. 1998;13:791-798.
59. Morrow D, Leirer V, Altieri P, Tanke E. Elders' schema for taking medication: Implications for instruction design. J Gerontol B. 1991;46:P378-P385.
60. Andrus MR, Roth MT. Health literacy: A review. Pharmacotherapy. 2002;22:282-302.
61. Morrow D, Leiter V, Altieri P. List formats improve medication instructions for older adults. Educ Gerontol. 1995;21:151-166.
62. Morrow DG, Leirer VO, Andrassy JM, et al. Medication instruction design: Younger and older adult schemas for taking medication. Hum Factors. 1996;38:556-573.
63. Aday LA, Andersen R. A framework for the study of access to medical care. Health Serv Res. 1974;9:208-220.
64. Cohen SJ. Improving patients compliance with therapeutic regimens. J Indiana State Med Assoc. 1983;76: 26-29.
65. Morrow D. Improving consultations between healthcare professionals and older clients: Implications for pharmacists. Int J Aging Hum Dev. 1997;44:47-72.
66. Andersen RM. Revisiting the behavioral model and access to medical care: Does it matter? J Health Soc Behav. 1995;36:1-10.
67. Morrow DG, Hier CM, Menard WE, Leiter VO. Icons improve older and younger adults' comprehension of medication information. J Gerontol B. 1998;53:P240-P254.
68. Murray MD, Deer MM, Ferguson JA, et al. Open-label randomized trial of torsemide compared with furosemide therapy for patients with heart failure. Am J Med. 2001; 111:513-520.
69. Meyer ME. Coping with Medications. San Diego, Calif: Singular Publishing Group; 1993.