A method for calculating adherence to polypharmacy from dispensing data records

International Journal of Clinical Pharmacy

Volumn 36, Issue 1, 2014, Pages 192-201

  Arnet, Isabelle ^a   Abraham, Ivo ^b   Messerli, Markus ^a   Hersberger, Kurt E ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b UNIVERSITY OF ARIZONA   (United States)

Author keywords

Adherence; Compliance; Daily polypharmacy possession ratio; Medication possession ratio; Pharmacy claims; Polypharmacy; Refill data

Indexed keywords

ARTICLE; CALCULATION; DAILY POLYPHARMACY POSSESSION RATIO; DATA BASE; FACE VALIDITY; MEDICAL INFORMATICS; MEDICAL RECORD; MEDICATION COMPLIANCE; MEDICATION POSSESSION RATIO; OBSERVATION; OUTCOME ASSESSMENT; PHARMACY; POLYPHARMACY; PRIORITY JOURNAL; REIMBURSEMENT; SWITZERLAND; AGED; FACTUAL DATABASE; FEMALE; HUMAN; MALE; STATISTICS AND NUMERICAL DATA; VALIDATION STUDY;

AGED; DATABASES, FACTUAL; FEMALE; HUMANS; MALE; MEDICATION ADHERENCE; PHARMACEUTICAL SERVICES; POLYPHARMACY;

EID: 84899482381     PISSN: 22107703     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11096-013-9891-8     Document Type: Article

References (23)

1. Anonymous. Patient compliance in therapeutic trials. Lancet 1991;337(8745):823-4.
2. Hamilton R, Briceland L. Use of prescription-refill records to assess patient compliance. Am J Hosp Pharm. 1992;49(7):1691-6.
3. Andrade S, Kahler KH, Frech F, Chan K. Methods for evaluation of medication adherence and persistence using automated databases. Pharmacoepidemiol Drug Saf. 2006;15(8):565-74. (Pubitemid 44336271)
4. Martin BC, Wiley-Exley EK, Richards S, Domino ME, Carey TS, Sleath BL. Contrasting measures of adherence with simple drug use, medication switching, and therapeutic duplication. Ann Pharmacother. 2009;43(1):36-44.
5. Lien CTC, Gillespie ND, Struthers AD, McMurdo MET. Heart failure in frail elderly patients: diagnostic difficulties, co-morbidities, polypharmacy and treatment dilemmas. Eur J Heart Fail. 2002;4(1):91-8. (Pubitemid 34113333)
6. Fulton MM, Riley Allen E. Polypharmacy in the elderly: a literature review. J Am Acad Nurse Pract. 2005;17(4):123-32.
7. Kingsbury S, Yi D, Simpson G. Psychopharmacology: rational and irrational polypharmacy. Psychiatr Serv. 2001;52(8):1033-6.
8. ESH/ESC Task Force for the Management of Arterial Hypertension. 2013 Practice guidelines for the management of arterial hypertension of the European Society of Hypertension (ESH) and the European Society of Cardiology (ESC): ESH/ESC Task Force for the Management of Arterial Hypertension. J Hypertens. 2013;31(10):1925-38.
9. Marcum ZA, Gellad WF. Medication adherence to multidrug regimens. Clin Geriatr Med. 2012;28(2):287-300.
10. World Health Organization. Adherence to long-term therapies - evidence for action. 2003. p. 1-194. Published Online www.who.int/chp/knowledge/ publications/adherence-report/en/. Last access 21 Oct 2013.
11. Doro P, Benko R, Kosik E, Matuz M, Toth K, Soos G. Utilization of oral antihyperglycemic drugs over a 7-year period (1998-2004) in a Hungarian population and adherence to drug therapy. Eur J Clin Pharmacol. 2005;61(12):893-7. (Pubitemid 41803699)
12. Sajatovic M, Valenstein M, Blow FC, Ganoczy D, Ignacio RV. Treatment adherence with antipsychotic medications in bipolar disorder. Bipolar Disord. 2006;8(3):232-41.
13. Steiner JF, Fihn SD, Blair B, Inui TS. Appropriate reductions in compliance among well-controlled hypertensive patients. J Clin Epidemiol. 1991;44(12):1361-71.
14. Steiner JF, Koepsell TD, Fihn SD, Inui TS. A general method of compliance assessment using centralized pharmacy records: description and validation. Med Care. 1988;26(8):814-23.
15. van Bruggen R, Gorter K, Stolk RP, Zuithoff P, Klungel OH, Rutten GEHM. Refill adherence and polypharmacy among patients with type 2 diabetes in general practice. Pharmacoepidemiol Drug Saf. 2009;18(11):983-91.
16. Salanitro A, Kripalani S. Prescription refill management and its effect on adherence: comment on "the implications of therapeutic complexity on adherence to cardiovascular medications". Arch Intern Med. 2011;171(9):822-3.
17. Steiner JF, Prochazka AV. The assessment of refill compliance using pharmacy records: methods, validity, and applications. J Clin Epidemiol. 1997;50(1):105-16. (Pubitemid 27089212)
18. Hess LM, Raebel MA, Conner DA, Malone DC. Measurement of adherence in pharmacy administrative databases: a proposal for standard definitions and preferred measures. Ann Pharmacother. 2006;40(7-8):1280-8. (Pubitemid 44204957)
19. Yeaw J, Benner J, Walt J, Sian S, Smith D. Comparing adherence and persistence across 6 chronic medication classes. J Manag Care Pharm. 2009;15(9):728-40.
20. Lau HS, de Boer A, Beuning KS, Porsius A. Validation of pharmacy records in drug exposure assessment. J Clin Epidemiol. 1997;50(5):619-25. (Pubitemid 27270212)
21. Peterson AM, Nau DP, Cramer JA, Benner J, Gwadry-Sridhar F, Nichol M. A checklist for medication compliance and persistence studies using retrospective databases. Value Health. 2007;10(1):3-12. (Pubitemid 46161090)
22. Mabotuwana T, Warren J, Kennelly J. A computational frame-work to identify patients with poor adherence to blood pressure lowering medication. Int J Med Inform. 2009;78(11):745-56.
23. Harrigan PR, Hogg RS, Dong WWY, Yip B, Wynhoven B, Woodward J, et al. Predictors of HIV drug-resistance mutations in a large antiretroviral-naive cohort initiating triple antiretroviral therapy. J Infect Dis. 2005;191(3):339-47. (Pubitemid 40139758)