메뉴 건너뛰기




Volumn 231, Issue , 2017, Pages 34-40

Manipulation of the innate immune response by human papillomaviruses

Author keywords

Inflammasome; Interferons; JAK STAT pathway; PAMPs

Indexed keywords

ATM PROTEIN; ATR PROTEIN; CYTOKINE; DNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; JANUS KINASE; STAT5 PROTEIN; VIRAL PROTEIN; ATM PROTEIN, HUMAN; ATR PROTEIN, HUMAN; ONCOPROTEIN;

EID: 85006852231     PISSN: 01681702     EISSN: 18727492     Source Type: Journal    
DOI: 10.1016/j.virusres.2016.11.004     Document Type: Review
Times cited : (44)

References (60)
  • 1
    • 0004235781 scopus 로고    scopus 로고
    • Cellular and Molecular Immunology
    • eighth edition ELSEVIER SAUNDERS
    • Abbas, A.K., Lichtman, A.H., Pillai, S., Cellular and Molecular Immunology. eighth edition, 2015, ELSEVIER SAUNDERS.
    • (2015)
    • Abbas, A.K.1    Lichtman, A.H.2    Pillai, S.3
  • 2
    • 54549103311 scopus 로고    scopus 로고
    • Inactivation of the CYLD deubiquitinase by HPV E6 mediates hypoxia-induced NF-kappaB activation
    • An, J., Mo, D., Liu, H., Veena, M.S., Srivatsan, E.S., Massoumi, R., Rettig, M.B., Inactivation of the CYLD deubiquitinase by HPV E6 mediates hypoxia-induced NF-kappaB activation. Cancer Cell 14 (2008), 394–407, 10.1016/j.ccr.2008.10.007.
    • (2008) Cancer Cell , vol.14 , pp. 394-407
    • An, J.1    Mo, D.2    Liu, H.3    Veena, M.S.4    Srivatsan, E.S.5    Massoumi, R.6    Rettig, M.B.7
  • 3
    • 0033526860 scopus 로고    scopus 로고
    • The human papillomavirus E7 oncoprotein abrogates signaling mediated by interferon-alpha
    • Barnard, P., McMillan, N.A., The human papillomavirus E7 oncoprotein abrogates signaling mediated by interferon-alpha. Virology 259 (1999), 305–313, 10.1006/viro.1999.9771.
    • (1999) Virology , vol.259 , pp. 305-313
    • Barnard, P.1    McMillan, N.A.2
  • 4
    • 78650748371 scopus 로고    scopus 로고
    • Persistence of human papillomavirus infection: keys to malignant progression
    • Bodily, J., Laimins, L.A., Persistence of human papillomavirus infection: keys to malignant progression. Trends Microbiol. 19 (2011), 33–39, 10.1016/j.tim.2010.10.002.
    • (2011) Trends Microbiol. , vol.19 , pp. 33-39
    • Bodily, J.1    Laimins, L.A.2
  • 5
  • 6
    • 84967215091 scopus 로고    scopus 로고
    • Viral evasion of intracellular DNA and RNA sensing
    • Chan, Y.K., Gack, M.U., Viral evasion of intracellular DNA and RNA sensing. Nat. Rev. Microbiol. 14 (2016), 360–373, 10.1038/nrmicro.2016.45.
    • (2016) Nat. Rev. Microbiol. , vol.14 , pp. 360-373
    • Chan, Y.K.1    Gack, M.U.2
  • 7
    • 0033998608 scopus 로고    scopus 로고
    • Microarray analysis identifies interferon-inducible genes and Stat-1 as major transcriptional targets of human papillomavirus type 31
    • Chang, Y.E., Laimins, L.A., Microarray analysis identifies interferon-inducible genes and Stat-1 as major transcriptional targets of human papillomavirus type 31. J. Virol. 74 (2000), 4174–4182.
    • (2000) J. Virol. , vol.74 , pp. 4174-4182
    • Chang, Y.E.1    Laimins, L.A.2
  • 8
    • 84920547918 scopus 로고    scopus 로고
    • Response of host inflammasomes to viral infection
    • Chen, I.-Y., Ichinohe, T., Response of host inflammasomes to viral infection. Trends Microbiol. 23 (2015), 55–63, 10.1016/j.tim.2014.09.007.
    • (2015) Trends Microbiol. , vol.23 , pp. 55-63
    • Chen, I.-Y.1    Ichinohe, T.2
  • 9
    • 67249144899 scopus 로고    scopus 로고
    • Unphosphorylated STAT1 prolongs the expression of interferon-induced immune regulatory genes
    • Cheon, H., Stark, G.R., Unphosphorylated STAT1 prolongs the expression of interferon-induced immune regulatory genes. Proc. Natl. Acad. Sci. U. S. A. 106 (2009), 9373–9378, 10.1073/pnas.0903487106.
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 9373-9378
    • Cheon, H.1    Stark, G.R.2
  • 11
    • 84937723908 scopus 로고    scopus 로고
    • The nuclear DNA sensor IFI16 acts as a restriction factor for human papillomavirus replication through epigenetic modifications of the viral promoters
    • Lo Cigno, I., De Andrea, M., Borgogna, C., Albertini, S., Landini, M.M., Peretti, A., Johnson, K.E., Chandran, B., Landolfo, S., Gariglio, M., The nuclear DNA sensor IFI16 acts as a restriction factor for human papillomavirus replication through epigenetic modifications of the viral promoters. J. Virol. 89 (2015), 7506–7520, 10.1128/JVI. 00013-15.
    • (2015) J. Virol. , vol.89 , pp. 7506-7520
    • Lo Cigno, I.1    De Andrea, M.2    Borgogna, C.3    Albertini, S.4    Landini, M.M.5    Peretti, A.6    Johnson, K.E.7    Chandran, B.8    Landolfo, S.9    Gariglio, M.10
  • 12
    • 45049083616 scopus 로고    scopus 로고
    • The E6E7 oncoproteins of cutaneous human papillomavirus type 38 interfere with the interferon pathway
    • Cordano, P., Gillan, V., Bratlie, S., Bouvard, V., Banks, L., Tommasino, M., Campo, M.S., The E6E7 oncoproteins of cutaneous human papillomavirus type 38 interfere with the interferon pathway. Virology 377 (2008), 408–418, 10.1016/j.virol.2008.04.036.
    • (2008) Virology , vol.377 , pp. 408-418
    • Cordano, P.1    Gillan, V.2    Bratlie, S.3    Bouvard, V.4    Banks, L.5    Tommasino, M.6    Campo, M.S.7
  • 13
    • 84871484827 scopus 로고    scopus 로고
    • The broad-spectrum antiviral functions of IFIT and IFITM proteins
    • Diamond, M.S., Farzan, M., The broad-spectrum antiviral functions of IFIT and IFITM proteins. Nat. Rev. Immunol. 13 (2013), 46–57, 10.1038/nri3344.
    • (2013) Nat. Rev. Immunol. , vol.13 , pp. 46-57
    • Diamond, M.S.1    Farzan, M.2
  • 14
    • 0003763255 scopus 로고    scopus 로고
    • Lippincott's Illustrated Reviews: Immunology
    • Wolters Kluwer Health/Lippincott Williams & Wilkins
    • Doan, T., Melvold, R., Viselli, S., Waltenbaugh, C., Lippincott's Illustrated Reviews: Immunology. 2008, Wolters Kluwer Health/Lippincott Williams & Wilkins.
    • (2008)
    • Doan, T.1    Melvold, R.2    Viselli, S.3    Waltenbaugh, C.4
  • 15
    • 0024535228 scopus 로고
    • The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product
    • Dyson, N., Howley, P.M., Munger, K., Harlow, E., The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product. Science 243 (1989), 934–937.
    • (1989) Science , vol.243 , pp. 934-937
    • Dyson, N.1    Howley, P.M.2    Munger, K.3    Harlow, E.4
  • 16
    • 84944463522 scopus 로고    scopus 로고
    • MiR-125a suppresses tumor growth, invasion and metastasis in cervical cancer by targeting STAT3
    • Fan, Z., Cui, H., Xu, X., Lin, Z., Zhang, X., Kang, L., Han, B., Meng, J., Yan, Z., Yan, X., Jiao, S., MiR-125a suppresses tumor growth, invasion and metastasis in cervical cancer by targeting STAT3. Oncotarget 6 (2015), 25266–25280, 10.18632/oncotarget.4457.
    • (2015) Oncotarget , vol.6 , pp. 25266-25280
    • Fan, Z.1    Cui, H.2    Xu, X.3    Lin, Z.4    Zhang, X.5    Kang, L.6    Han, B.7    Meng, J.8    Yan, Z.9    Yan, X.10    Jiao, S.11
  • 17
    • 84882896267 scopus 로고    scopus 로고
    • Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses
    • Gao, D., Wu, J., Wu, Y.-T., Du, F., Aroh, C., Yan, N., Sun, L., Chen, Z.J., Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses. Science 341 (2013), 903–906, 10.1126/science.1240933.
    • (2013) Science , vol.341 , pp. 903-906
    • Gao, D.1    Wu, J.2    Wu, Y.-T.3    Du, F.4    Aroh, C.5    Yan, N.6    Sun, L.7    Chen, Z.J.8
  • 20
    • 0036559896 scopus 로고    scopus 로고
    • Papillomaviruses and cancer: from basic studies to clinical application
    • zur Hausen, H., Papillomaviruses and cancer: from basic studies to clinical application. Nat. Rev. Cancer 2 (2002), 342–350, 10.1038/nrc798.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 342-350
    • zur Hausen, H.1
  • 21
    • 33645211201 scopus 로고    scopus 로고
    • Human papillomaviruses: basic mechanisms of pathogenesis and oncogenicity
    • Hebner, C.M., Laimins, L.A., Human papillomaviruses: basic mechanisms of pathogenesis and oncogenicity. Rev. Med. Virol. 16 (2006), 83–97, 10.1002/rmv.488.
    • (2006) Rev. Med. Virol. , vol.16 , pp. 83-97
    • Hebner, C.M.1    Laimins, L.A.2
  • 22
    • 33750264663 scopus 로고    scopus 로고
    • Human papillomaviruses target the double-stranded RNA protein kinase pathway
    • Hebner, C.M., Wilson, R., Rader, J., Bidder, M., Laimins, L.A., Human papillomaviruses target the double-stranded RNA protein kinase pathway. J. Gen. Virol. 87 (2006), 3183–3193, 10.1099/vir.0. 82098-0.
    • (2006) J. Gen. Virol. , vol.87 , pp. 3183-3193
    • Hebner, C.M.1    Wilson, R.2    Rader, J.3    Bidder, M.4    Laimins, L.A.5
  • 23
    • 36348949210 scopus 로고    scopus 로고
    • Human papillomavirus E6 proteins mediate resistance to interferon-induced growth arrest through inhibition of p53 acetylation
    • Hebner, C., Beglin, M., Laimins, L.A., Human papillomavirus E6 proteins mediate resistance to interferon-induced growth arrest through inhibition of p53 acetylation. J. Virol. 81 (2007), 12740–12747, 10.1128/JVI. 00987-07.
    • (2007) J. Virol. , vol.81 , pp. 12740-12747
    • Hebner, C.1    Beglin, M.2    Laimins, L.A.3
  • 24
    • 84859159648 scopus 로고    scopus 로고
    • The role of STAT5 in lymphocyte development and transformation
    • Heltemes-Harris, L.M., Farrar, M.A., The role of STAT5 in lymphocyte development and transformation. Curr. Opin. Immunol. 24 (2012), 146–152, 10.1016/j.coi.2012.01.015.
    • (2012) Curr. Opin. Immunol. , vol.24 , pp. 146-152
    • Heltemes-Harris, L.M.1    Farrar, M.A.2
  • 25
    • 84876866677 scopus 로고    scopus 로고
    • The JAK-STAT transcriptional regulator, STAT-5, activates the ATM DNA damage pathway to induce HPV 31 genome amplification upon epithelial differentiation
    • Hong, S., Laimins, L.A., The JAK-STAT transcriptional regulator, STAT-5, activates the ATM DNA damage pathway to induce HPV 31 genome amplification upon epithelial differentiation. PLoS Pathog., 9, 2013, e1003295, 10.1371/journal.ppat.1003295.
    • (2013) PLoS Pathog. , vol.9 , pp. e1003295
    • Hong, S.1    Laimins, L.A.2
  • 26
    • 80052474239 scopus 로고    scopus 로고
    • Suppression of STAT-1 expression by human papillomaviruses is necessary for differentiation-dependent genome amplification and plasmid maintenance
    • Hong, S., Mehta, K.P., Laimins, L.A., Suppression of STAT-1 expression by human papillomaviruses is necessary for differentiation-dependent genome amplification and plasmid maintenance. J. Virol. 85 (2011), 9486–9494, 10.1128/JVI.05007-11.
    • (2011) J. Virol. , vol.85 , pp. 9486-9494
    • Hong, S.1    Mehta, K.P.2    Laimins, L.A.3
  • 27
    • 84925433462 scopus 로고    scopus 로고
    • The acetyltransferase Tip60 is a critical regulator of the differentiation-dependent amplification of human papillomaviruses
    • Hong, S., Dutta, A., Laimins, L.A., The acetyltransferase Tip60 is a critical regulator of the differentiation-dependent amplification of human papillomaviruses. J. Virol. 89 (2015), 4668–4675, 10.1128/JVI. 03455-14.
    • (2015) J. Virol. , vol.89 , pp. 4668-4675
    • Hong, S.1    Dutta, A.2    Laimins, L.A.3
  • 28
    • 0036333799 scopus 로고    scopus 로고
    • Down regulation of the interleukin-8 promoter by human papillomavirus type 16 E6 and E7 through effects on CREB binding protein/p300 and P/CAF
    • Huang, S.-M., McCance, D.J., Down regulation of the interleukin-8 promoter by human papillomavirus type 16 E6 and E7 through effects on CREB binding protein/p300 and P/CAF. J. Virol. 76 (2002), 8710–8721, 10.1128/JVI.76.17.
    • (2002) J. Virol. , vol.76 , pp. 8710-8721
    • Huang, S.-M.1    McCance, D.J.2
  • 29
    • 0025932933 scopus 로고
    • A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18
    • Huibregtse, J.M., Scheffner, M., Howley, P.M., A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18. EMBO J. 10 (1991), 4129–4135.
    • (1991) EMBO J. , vol.10 , pp. 4129-4135
    • Huibregtse, J.M.1    Scheffner, M.2    Howley, P.M.3
  • 30
    • 1842505312 scopus 로고    scopus 로고
    • Control of alpha subunit of eukaryotic translation initiation factor 2 (eIF2 alpha) phosphorylation by the human papillomavirus type 18 E6 oncoprotein: implications for eIF2 alpha-dependent gene expression and cell death
    • Kazemi, S., Papadopoulou, S., Li, S., Su, Q., Wang, S., Yoshimura, A., Matlashewski, G., Dever, T.E., Koromilas, A.E., Control of alpha subunit of eukaryotic translation initiation factor 2 (eIF2 alpha) phosphorylation by the human papillomavirus type 18 E6 oncoprotein: implications for eIF2 alpha-dependent gene expression and cell death. Mol. Cell Biol. 24 (2004), 3415–3429, 10.1128/MCB.24.8.
    • (2004) Mol. Cell Biol. , vol.24 , pp. 3415-3429
    • Kazemi, S.1    Papadopoulou, S.2    Li, S.3    Su, Q.4    Wang, S.5    Yoshimura, A.6    Matlashewski, G.7    Dever, T.E.8    Koromilas, A.E.9
  • 31
    • 77249119657 scopus 로고    scopus 로고
    • Interferon regulatory factor (IRF)-2 activates the HPV-16 E6-E7 promoter in keratinocytes
    • Lace, M.J., Anson, J.R., Haugen, T.H., Turek, L.P., Interferon regulatory factor (IRF)-2 activates the HPV-16 E6-E7 promoter in keratinocytes. Virology 399 (2010), 270–279, 10.1016/j.virol.2009.12.025.
    • (2010) Virology , vol.399 , pp. 270-279
    • Lace, M.J.1    Anson, J.R.2    Haugen, T.H.3    Turek, L.P.4
  • 32
    • 0033554631 scopus 로고    scopus 로고
    • The human papilloma virus (HPV)-18 E6 oncoprotein physically associates with Tyk2 and impairs Jak-STAT activation by interferon-alpha
    • Li, S., Labrecque, S., Gauzzi, M.C., Cuddihy, A.R., Wong, A.H., Pellegrini, S., Matlashewski, G.J., Koromilas, A.E., The human papilloma virus (HPV)-18 E6 oncoprotein physically associates with Tyk2 and impairs Jak-STAT activation by interferon-alpha. Oncogene 18 (1999), 5727–5737, 10.1038/sj.onc.1202960.
    • (1999) Oncogene , vol.18 , pp. 5727-5737
    • Li, S.1    Labrecque, S.2    Gauzzi, M.C.3    Cuddihy, A.R.4    Wong, A.H.5    Pellegrini, S.6    Matlashewski, G.J.7    Koromilas, A.E.8
  • 33
    • 20044366070 scopus 로고    scopus 로고
    • HPV31 E7 facilitates replication by activating E2F2 transcription through its interaction with HDACs
    • Longworth, M.S., Wilson, R., Laimins, L.A., HPV31 E7 facilitates replication by activating E2F2 transcription through its interaction with HDACs. EMBO J. 24 (2005), 1821–1830, 10.1038/sj.emboj.7600651.
    • (2005) EMBO J. , vol.24 , pp. 1821-1830
    • Longworth, M.S.1    Wilson, R.2    Laimins, L.A.3
  • 34
    • 79956314622 scopus 로고    scopus 로고
    • Immune signaling by RIG-I-like receptors
    • Loo, Y.-M., Gale, M., Immune signaling by RIG-I-like receptors. Immunity 34 (2011), 680–692, 10.1016/j.immuni.2011.05.003.
    • (2011) Immunity , vol.34 , pp. 680-692
    • Loo, Y.-M.1    Gale, M.2
  • 36
    • 73349125474 scopus 로고    scopus 로고
    • Human papillomaviruses activate the ATM DNA damage pathway for viral genome amplification upon differentiation
    • Moody, C.A., Laimins, L.A., Human papillomaviruses activate the ATM DNA damage pathway for viral genome amplification upon differentiation. PLoS Pathog., 5, 2009, e1000605, 10.1371/journal.ppat.1000605.
    • (2009) PLoS Pathog. , vol.5 , pp. e1000605
    • Moody, C.A.1    Laimins, L.A.2
  • 37
    • 0036849734 scopus 로고    scopus 로고
    • Human papillomavirus immortalization and transformation functions
    • Munger, K., Howley, P.M., Human papillomavirus immortalization and transformation functions. Virus Res. 89 (2002), 213–228.
    • (2002) Virus Res. , vol.89 , pp. 213-228
    • Munger, K.1    Howley, P.M.2
  • 38
    • 0024809865 scopus 로고
    • Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product
    • Munger, K., Werness, B.A., Dyson, N., Phelps, W.C., Harlow, E., Howley, P.M., Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product. EMBO J. 8 (1989), 4099–4105.
    • (1989) EMBO J. , vol.8 , pp. 4099-4105
    • Munger, K.1    Werness, B.A.2    Dyson, N.3    Phelps, W.C.4    Harlow, E.5    Howley, P.M.6
  • 40
    • 0035047160 scopus 로고    scopus 로고
    • Papillomavirus type 16 oncogenes downregulate expression of interferon-responsive genes and upregulate proliferation-associated and NF-kappaB-responsive genes in cervical keratinocytes
    • Nees, M., Geoghegan, J.M., Hyman, T., Frank, S., Miller, L., Woodworth, C.D., Papillomavirus type 16 oncogenes downregulate expression of interferon-responsive genes and upregulate proliferation-associated and NF-kappaB-responsive genes in cervical keratinocytes. J. Virol. 75 (2001), 4283–4296, 10.1128/JVI.75.9.4283-4296.2001.
    • (2001) J. Virol. , vol.75 , pp. 4283-4296
    • Nees, M.1    Geoghegan, J.M.2    Hyman, T.3    Frank, S.4    Miller, L.5    Woodworth, C.D.6
  • 41
    • 84883368914 scopus 로고    scopus 로고
    • Post-translational control of IL-1β via the human papillomavirus type 16 E6 oncoprotein: a novel mechanism of innate immune escape mediated by the E3-ubiquitin ligase E6-AP and p53
    • Niebler, M., Qian, X., Höfler, D., Kogosov, V., Kaewprag, J., Kaufmann, A.M., Ly, R., Böhmer, G., Zawatzky, R., Rösl, F., Rincon-Orozco, B., Post-translational control of IL-1β via the human papillomavirus type 16 E6 oncoprotein: a novel mechanism of innate immune escape mediated by the E3-ubiquitin ligase E6-AP and p53. PLoS Pathog., 9, 2013, e1003536, 10.1371/journal.ppat.1003536.
    • (2013) PLoS Pathog. , vol.9 , pp. e1003536
    • Niebler, M.1    Qian, X.2    Höfler, D.3    Kogosov, V.4    Kaewprag, J.5    Kaufmann, A.M.6    Ly, R.7    Böhmer, G.8    Zawatzky, R.9    Rösl, F.10    Rincon-Orozco, B.11
  • 43
    • 84945937892 scopus 로고    scopus 로고
    • Downregulation of toll-like receptor 9 expression by beta human papillomavirus 38 and implications for cell cycle control
    • Pacini, L., Savini, C., Ghittoni, R., Saidj, D., Lamartine, J., Hasan, U.A., Accardi, R., Tommasino, M., Downregulation of toll-like receptor 9 expression by beta human papillomavirus 38 and implications for cell cycle control. J. Virol. 89 (2015), 11396–11405, 10.1128/JVI. 02151-15.
    • (2015) J. Virol. , vol.89 , pp. 11396-11405
    • Pacini, L.1    Savini, C.2    Ghittoni, R.3    Saidj, D.4    Lamartine, J.5    Hasan, U.A.6    Accardi, R.7    Tommasino, M.8
  • 44
    • 0034629279 scopus 로고    scopus 로고
    • Inactivation of interferon regulatory factor-1 tumor suppressor protein by HPV E7 oncoprotein. Implication for the E7-mediated immune evasion mechanism in cervical carcinogenesis
    • Park, J.S., Kim, E.J., Kwon, H.J., Hwang, E.S., Namkoong, S.E., Um, S.J., Inactivation of interferon regulatory factor-1 tumor suppressor protein by HPV E7 oncoprotein. Implication for the E7-mediated immune evasion mechanism in cervical carcinogenesis. J. Biol. Chem. 275 (2000), 6764–6769.
    • (2000) J. Biol. Chem. , vol.275 , pp. 6764-6769
    • Park, J.S.1    Kim, E.J.2    Kwon, H.J.3    Hwang, E.S.4    Namkoong, S.E.5    Um, S.J.6
  • 45
    • 84894515095 scopus 로고    scopus 로고
    • TRIMmunity: the roles of the TRIM E3-ubiquitin ligase family in innate antiviral immunity
    • Rajsbaum, R., García-Sastre, A., Versteeg, G.A., TRIMmunity: the roles of the TRIM E3-ubiquitin ligase family in innate antiviral immunity. J. Mol. Biol. 426 (2014), 1265–1284, 10.1016/j.jmb.2013.12.005.
    • (2014) J. Mol. Biol. , vol.426 , pp. 1265-1284
    • Rajsbaum, R.1    García-Sastre, A.2    Versteeg, G.A.3
  • 47
    • 80055107582 scopus 로고    scopus 로고
    • High-risk human papillomaviruses repress constitutive kappa interferon transcription via E6 to prevent pathogen recognition receptor and antiviral-gene expression
    • Reiser, J., Hurst, J., Voges, M., Krauss, P., Münch, P., Iftner, T., Stubenrauch, F., High-risk human papillomaviruses repress constitutive kappa interferon transcription via E6 to prevent pathogen recognition receptor and antiviral-gene expression. J. Virol. 85 (2011), 11372–11380, 10.1128/JVI. 05279-11.
    • (2011) J. Virol. , vol.85 , pp. 11372-11380
    • Reiser, J.1    Hurst, J.2    Voges, M.3    Krauss, P.4    Münch, P.5    Iftner, T.6    Stubenrauch, F.7
  • 48
    • 84939442208 scopus 로고    scopus 로고
    • The human papillomavirus (HPV) E7 protein antagonises an Imiquimod-induced inflammatory pathway in primary human keratinocytes
    • Richards, K.H., Wasson, C.W., Watherston, O., Doble, R., Blair, G.E., Wittmann, M., Macdonald, A., The human papillomavirus (HPV) E7 protein antagonises an Imiquimod-induced inflammatory pathway in primary human keratinocytes. Sci. Rep., 5, 2015, 12922, 10.1038/srep12922.
    • (2015) Sci. Rep. , vol.5 , pp. 12922
    • Richards, K.H.1    Wasson, C.W.2    Watherston, O.3    Doble, R.4    Blair, G.E.5    Wittmann, M.6    Macdonald, A.7
  • 50
    • 0032128003 scopus 로고    scopus 로고
    • Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activity
    • Ronco, L.V., Karpova, A.Y., Vidal, M., Howley, P.M., Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activity. Genes Dev. 12 (1998), 2061–2072.
    • (1998) Genes Dev. , vol.12 , pp. 2061-2072
    • Ronco, L.V.1    Karpova, A.Y.2    Vidal, M.3    Howley, P.M.4
  • 51
    • 0025639158 scopus 로고
    • The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
    • Scheffner, M., Werness, B.A., Huibregtse, J.M., Levine, A.J., Howley, P.M., The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell 63 (1990), 1129–1136.
    • (1990) Cell , vol.63 , pp. 1129-1136
    • Scheffner, M.1    Werness, B.A.2    Huibregtse, J.M.3    Levine, A.J.4    Howley, P.M.5
  • 52
    • 0027358723 scopus 로고
    • The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
    • Scheffner, M., Huibregtse, J.M., Vierstra, R.D., Howley, P.M., The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell 75 (1993), 495–505.
    • (1993) Cell , vol.75 , pp. 495-505
    • Scheffner, M.1    Huibregtse, J.M.2    Vierstra, R.D.3    Howley, P.M.4
  • 53
    • 32644456874 scopus 로고    scopus 로고
    • Antiviral innate immunity pathways
    • Seth, R.B., Sun, L., Chen, Z.J., Antiviral innate immunity pathways. Cell Res. 16 (2006), 141–147, 10.1038/sj.cr.7310019.
    • (2006) Cell Res. , vol.16 , pp. 141-147
    • Seth, R.B.1    Sun, L.2    Chen, Z.J.3
  • 55
    • 0037067782 scopus 로고    scopus 로고
    • The human papillomavirus oncoprotein E7 attenuates NF-kappa B activation by targeting the Ikappa B kinase complex
    • Spitkovsky, D., Hehner, S.P., Hofmann, T.G., Möller, A., Schmitz, M.L., The human papillomavirus oncoprotein E7 attenuates NF-kappa B activation by targeting the Ikappa B kinase complex. J. Biol. Chem. 277 (2002), 25576–25582, 10.1074/jbc.M201884200.
    • (2002) J. Biol. Chem. , vol.277 , pp. 25576-25582
    • Spitkovsky, D.1    Hehner, S.P.2    Hofmann, T.G.3    Möller, A.4    Schmitz, M.L.5
  • 56
    • 84873711885 scopus 로고    scopus 로고
    • Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway
    • Sun, L., Wu, J., Du, F., Chen, X., Chen, Z.J., Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway. Science 339 (2013), 786–791, 10.1126/science.1232458.
    • (2013) Science , vol.339 , pp. 786-791
    • Sun, L.1    Wu, J.2    Du, F.3    Chen, X.4    Chen, Z.J.5
  • 58
    • 58049208165 scopus 로고    scopus 로고
    • Interferon-inducible protein, P56, inhibits HPV DNA replication by binding to the viral protein E1
    • Terenzi, F., Saikia, P., Sen, G.C., Interferon-inducible protein, P56, inhibits HPV DNA replication by binding to the viral protein E1. EMBO J. 27 (2008), 3311–3321, 10.1038/emboj.2008.241.
    • (2008) EMBO J. , vol.27 , pp. 3311-3321
    • Terenzi, F.1    Saikia, P.2    Sen, G.C.3
  • 59
    • 84982085567 scopus 로고    scopus 로고
    • Cervical cancer stem cells selectively overexpress HPV oncoprotein E6 that controls stemness and self-renewal through upregulation of HES1
    • Tyagi, A., Vishnoi, K., Mahata, S., Verma, G., Srivastava, Y., Masaldan, S., Roy, B.G., Bharti, A.C., Das, B.C., Cervical cancer stem cells selectively overexpress HPV oncoprotein E6 that controls stemness and self-renewal through upregulation of HES1. Clin. Cancer Res. 22 (2016), 4170–4184, 10.1158/1078-0432.CCR-15-2574.
    • (2016) Clin. Cancer Res. , vol.22 , pp. 4170-4184
    • Tyagi, A.1    Vishnoi, K.2    Mahata, S.3    Verma, G.4    Srivastava, Y.5    Masaldan, S.6    Roy, B.G.7    Bharti, A.C.8    Das, B.C.9
  • 60
    • 84901366269 scopus 로고    scopus 로고
    • The antiviral restriction factors IFITM1, 2 and 3 do not inhibit infection of human papillomavirus, cytomegalovirus and adenovirus
    • Warren, C.J., Griffin, L.M., Little, A.S., Huang, I.-C., Farzan, M., Pyeon, D., The antiviral restriction factors IFITM1, 2 and 3 do not inhibit infection of human papillomavirus, cytomegalovirus and adenovirus. PLoS ONE, 9, 2014, e96579, 10.1371/journal.pone.0096579.
    • (2014) PLoS ONE , vol.9 , pp. e96579
    • Warren, C.J.1    Griffin, L.M.2    Little, A.S.3    Huang, I.-C.4    Farzan, M.5    Pyeon, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.