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Volumn 14, Issue , 2017, Pages 54-64

Individual differences in stress susceptibility and stress inhibitory mechanisms

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; BRAIN DERIVED NEUROTROPHIC FACTOR; CHAPERONE; CORTICOTROPIN RELEASING FACTOR; FK506 BINDING PROTEIN 51; GLUCOCORTICOID RECEPTOR; MINERALOCORTICOID RECEPTOR; UNCLASSIFIED DRUG;

EID: 85006839773     PISSN: None     EISSN: 23521546     Source Type: Journal    
DOI: 10.1016/j.cobeha.2016.11.016     Document Type: Review
Times cited : (102)

References (68)
  • 1
    • 84942411681 scopus 로고    scopus 로고
    • Mechanisms of stress in the brain
    • This excellent review provides an overview of the mechanisms and mediators through which stressors alter brain structure and function focusing primarily on corticolimbic regions.
    • 1•• McEwen, B.S., Bowles, N.P., Gray, J.D., Hill, M.N., Hunter, R.G., Karatsoreos, I.N., Nasca, C., Mechanisms of stress in the brain. Nat Neurosci 18 (2015), 1353–1363 This excellent review provides an overview of the mechanisms and mediators through which stressors alter brain structure and function focusing primarily on corticolimbic regions.
    • (2015) Nat Neurosci , vol.18 , pp. 1353-1363
    • McEwen, B.S.1    Bowles, N.P.2    Gray, J.D.3    Hill, M.N.4    Hunter, R.G.5    Karatsoreos, I.N.6    Nasca, C.7
  • 2
    • 84922259218 scopus 로고    scopus 로고
    • The organization of the stress system and its dysregulation in depressive illness
    • 2 Gold, P.W., The organization of the stress system and its dysregulation in depressive illness. Mol Psychiatry 20 (2015), 32–47.
    • (2015) Mol Psychiatry , vol.20 , pp. 32-47
    • Gold, P.W.1
  • 3
    • 54049133277 scopus 로고    scopus 로고
    • The molecular neurobiology of depression
    • 3 Krishnan, V., Nestler, E.J., The molecular neurobiology of depression. Nature 455 (2008), 894–902.
    • (2008) Nature , vol.455 , pp. 894-902
    • Krishnan, V.1    Nestler, E.J.2
  • 4
    • 84865971321 scopus 로고    scopus 로고
    • Neural mechanisms of stress resilience and vulnerability
    • 4 Franklin, T.B., Saab, B.J., Mansuy, I.M., Neural mechanisms of stress resilience and vulnerability. Neuron 75 (2012), 747–761.
    • (2012) Neuron , vol.75 , pp. 747-761
    • Franklin, T.B.1    Saab, B.J.2    Mansuy, I.M.3
  • 6
    • 84898752877 scopus 로고    scopus 로고
    • The NIMH Research Domain Criteria (RDoC) Project: precision medicine for psychiatry
    • 6 Insel, T.R., The NIMH Research Domain Criteria (RDoC) Project: precision medicine for psychiatry. Am J Psychiatry 171 (2014), 395–397.
    • (2014) Am J Psychiatry , vol.171 , pp. 395-397
    • Insel, T.R.1
  • 7
    • 20044395965 scopus 로고    scopus 로고
    • Stress and the brain: from adaptation to disease
    • This excellent review summarizes functional interactions between limbic brain circuits and the HPA axis and describes how imbalances in MR and GR signalling can increase vulnerability for mental illness.
    • 7•• de Kloet, E.R., Joels, M., Holsboer, F., Stress and the brain: from adaptation to disease. Nat Rev Neurosci 6 (2005), 463–475 This excellent review summarizes functional interactions between limbic brain circuits and the HPA axis and describes how imbalances in MR and GR signalling can increase vulnerability for mental illness.
    • (2005) Nat Rev Neurosci , vol.6 , pp. 463-475
    • de Kloet, E.R.1    Joels, M.2    Holsboer, F.3
  • 8
    • 67651108814 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms related to HPA axis reactivity
    • 8 Derijk, R.H., Single nucleotide polymorphisms related to HPA axis reactivity. Neuroimmunomodulation 16 (2009), 340–352.
    • (2009) Neuroimmunomodulation , vol.16 , pp. 340-352
    • Derijk, R.H.1
  • 9
    • 84907200981 scopus 로고    scopus 로고
    • Expression profiling associates blood and brain glucocorticoid receptor signaling with trauma-related individual differences in both sexes
    • 9 Daskalakis, N.P., Cohen, H., Cai, G., Buxbaum, J.D., Yehuda, R., Expression profiling associates blood and brain glucocorticoid receptor signaling with trauma-related individual differences in both sexes. Proc Natl Acad Sci U S A 111 (2014), 13529–13534.
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. 13529-13534
    • Daskalakis, N.P.1    Cohen, H.2    Cai, G.3    Buxbaum, J.D.4    Yehuda, R.5
  • 10
    • 84931041069 scopus 로고    scopus 로고
    • Epigenetics of stress-related psychiatric disorders and gene × environment interactions
    • 10 Klengel, T., Binder, E.B., Epigenetics of stress-related psychiatric disorders and gene × environment interactions. Neuron 86 (2015), 1343–1357.
    • (2015) Neuron , vol.86 , pp. 1343-1357
    • Klengel, T.1    Binder, E.B.2
  • 11
    • 84911394488 scopus 로고    scopus 로고
    • Epigenetic signaling in psychiatric disorders: stress and depression
    • 11 Bagot, R.C., Labonte, B., Pena, C.J., Nestler, E.J., Epigenetic signaling in psychiatric disorders: stress and depression. Dialogues Clin Neurosci 16 (2014), 281–295.
    • (2014) Dialogues Clin Neurosci , vol.16 , pp. 281-295
    • Bagot, R.C.1    Labonte, B.2    Pena, C.J.3    Nestler, E.J.4
  • 12
    • 84937201710 scopus 로고    scopus 로고
    • The effects of early life stress on the epigenome: from the womb to adulthood and even before
    • 12 Provencal, N., Binder, E.B., The effects of early life stress on the epigenome: from the womb to adulthood and even before. Exp Neurol 268 (2015), 10–20.
    • (2015) Exp Neurol , vol.268 , pp. 10-20
    • Provencal, N.1    Binder, E.B.2
  • 13
    • 77949746666 scopus 로고    scopus 로고
    • The role of BDNF and its receptors in depression and antidepressant drug action: reactivation of developmental plasticity
    • 13 Castren, E., Rantamaki, T., The role of BDNF and its receptors in depression and antidepressant drug action: reactivation of developmental plasticity. Dev Neurobiol 70 (2010), 289–297.
    • (2010) Dev Neurobiol , vol.70 , pp. 289-297
    • Castren, E.1    Rantamaki, T.2
  • 14
    • 84926126376 scopus 로고    scopus 로고
    • Pharmacology of cognitive enhancers for exposure-based therapy of fear, anxiety and trauma-related disorders
    • 14 Singewald, N., Schmuckermair, C., Whittle, N., Holmes, A., Ressler, K.J., Pharmacology of cognitive enhancers for exposure-based therapy of fear, anxiety and trauma-related disorders. Pharmacol Ther 149 (2015), 150–190.
    • (2015) Pharmacol Ther , vol.149 , pp. 150-190
    • Singewald, N.1    Schmuckermair, C.2    Whittle, N.3    Holmes, A.4    Ressler, K.J.5
  • 15
    • 84940486865 scopus 로고    scopus 로고
    • Sympathoneural and adrenomedullary responses to mental stress
    • 15 Carter, J.R., Goldstein, D.S., Sympathoneural and adrenomedullary responses to mental stress. Compr Physiol 5 (2015), 119–146.
    • (2015) Compr Physiol , vol.5 , pp. 119-146
    • Carter, J.R.1    Goldstein, D.S.2
  • 16
    • 85018001237 scopus 로고    scopus 로고
    • Regulation of the hypothalamic-pituitary-adrenocortical stress response
    • This review gives an excellent overview of neurochemical, neuropeptide, hormonal and neural mechanisms associated with HPA axis regulation as well as neuroanatomical details of stress inhibitory pathways in the brain.
    • 16• Herman, J.P., McKlveen, J.M., Ghosal, S., Kopp, B., Wulsin, A., Makinson, R., Scheimann, J., Myers, B., Regulation of the hypothalamic-pituitary-adrenocortical stress response. Compr Physiol 6 (2016), 603–621 This review gives an excellent overview of neurochemical, neuropeptide, hormonal and neural mechanisms associated with HPA axis regulation as well as neuroanatomical details of stress inhibitory pathways in the brain.
    • (2016) Compr Physiol , vol.6 , pp. 603-621
    • Herman, J.P.1    McKlveen, J.M.2    Ghosal, S.3    Kopp, B.4    Wulsin, A.5    Makinson, R.6    Scheimann, J.7    Myers, B.8
  • 18
    • 84931054209 scopus 로고    scopus 로고
    • Chronic stress impacts the cardiovascular system: animal models and clinical outcomes
    • 18 Golbidi, S., Frisbee, J.C., Laher, I., Chronic stress impacts the cardiovascular system: animal models and clinical outcomes. Am J Physiol Heart Circ Physiol 308 (2015), H1476–H1498.
    • (2015) Am J Physiol Heart Circ Physiol , vol.308 , pp. H1476-H1498
    • Golbidi, S.1    Frisbee, J.C.2    Laher, I.3
  • 19
    • 85013050293 scopus 로고    scopus 로고
    • Untangling the Neurobiology of Coping Styles in rodents: towards neural mechanisms underlying individual differences in disease susceptibility
    • A review that highlights biological basis of individual variation in stress reactivity in terms of individual coping styles in animals as they might be observed in nature. Moreover, authors discuss the proximate consequences of individual stress-coping variations with respect to neuroendocrine reactivity and relevance for differences in disease susceptibility.
    • 19•• de Boer, S.F., Buwalda, B., Koolhaas, J.M., Untangling the Neurobiology of Coping Styles in rodents: towards neural mechanisms underlying individual differences in disease susceptibility. Neurosci Biobehav Rev, 2016 A review that highlights biological basis of individual variation in stress reactivity in terms of individual coping styles in animals as they might be observed in nature. Moreover, authors discuss the proximate consequences of individual stress-coping variations with respect to neuroendocrine reactivity and relevance for differences in disease susceptibility.
    • (2016) Neurosci Biobehav Rev
    • de Boer, S.F.1    Buwalda, B.2    Koolhaas, J.M.3
  • 20
    • 84889662586 scopus 로고    scopus 로고
    • Individual differences and the characterization of animal models of psychopathology: a strong challenge and a good opportunity
    • 20 Armario, A., Nadal, R., Individual differences and the characterization of animal models of psychopathology: a strong challenge and a good opportunity. Front Pharmacol, 4, 2013, 137.
    • (2013) Front Pharmacol , vol.4 , pp. 137
    • Armario, A.1    Nadal, R.2
  • 21
    • 84942446711 scopus 로고    scopus 로고
    • Finding translation in stress research
    • 21 Hariri, A.R., Holmes, A., Finding translation in stress research. Nat Neurosci 18 (2015), 1347–1352.
    • (2015) Nat Neurosci , vol.18 , pp. 1347-1352
    • Hariri, A.R.1    Holmes, A.2
  • 22
  • 23
    • 77449090704 scopus 로고    scopus 로고
    • Stress hormone regulation: biological role and translation into therapy
    • C101–C111
    • 23 Holsboer, F., Ising, M., Stress hormone regulation: biological role and translation into therapy. Annu Rev Psychol 61 (2010), 81–109 C101–C111.
    • (2010) Annu Rev Psychol , vol.61 , pp. 81-109
    • Holsboer, F.1    Ising, M.2
  • 24
    • 84922764413 scopus 로고    scopus 로고
    • Differential impact of stress on hypothalamic-pituitary-adrenal axis: gene expression changes in Lewis and Fisher rats
    • 24 Ergang, P., Vodicka, M., Sotak, M., Klusonova, P., Behuliak, M., Rehakova, L., Zach, P., Pacha, J., Differential impact of stress on hypothalamic-pituitary-adrenal axis: gene expression changes in Lewis and Fisher rats. Psychoneuroendocrinology 53 (2015), 49–59.
    • (2015) Psychoneuroendocrinology , vol.53 , pp. 49-59
    • Ergang, P.1    Vodicka, M.2    Sotak, M.3    Klusonova, P.4    Behuliak, M.5    Rehakova, L.6    Zach, P.7    Pacha, J.8
  • 25
    • 78149415975 scopus 로고    scopus 로고
    • Different susceptibility to social defeat stress of BalbC and C57BL6/J mice
    • 25 Razzoli, M., Carboni, L., Andreoli, M., Ballottari, A., Arban, R., Different susceptibility to social defeat stress of BalbC and C57BL6/J mice. Behav Brain Res 216 (2011), 100–108.
    • (2011) Behav Brain Res , vol.216 , pp. 100-108
    • Razzoli, M.1    Carboni, L.2    Andreoli, M.3    Ballottari, A.4    Arban, R.5
  • 26
    • 35348832393 scopus 로고    scopus 로고
    • Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions
    • Using the social defeat paradigm in mice, authors demonstrate that a inbred C57Bl/6J mice can be separated into susceptible and unsusceptible individuals which can be used to identify some of the underlying molecular mechanisms.
    • 26•• Krishnan, V., Han, M.H., Graham, D.L., Berton, O., Renthal, W., Russo, S.J., Laplant, Q., Graham, A., Lutter, M., Lagace, D.C., et al. Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions. Cell 131 (2007), 391–404 Using the social defeat paradigm in mice, authors demonstrate that a inbred C57Bl/6J mice can be separated into susceptible and unsusceptible individuals which can be used to identify some of the underlying molecular mechanisms.
    • (2007) Cell , vol.131 , pp. 391-404
    • Krishnan, V.1    Han, M.H.2    Graham, D.L.3    Berton, O.4    Renthal, W.5    Russo, S.J.6    Laplant, Q.7    Graham, A.8    Lutter, M.9    Lagace, D.C.10
  • 27
    • 11844270463 scopus 로고    scopus 로고
    • Inter-individual vs line/strain differences in psychogenetically selected Roman High-(RHA) and Low-(RLA) Avoidance rats: neuroendocrine and behavioural aspects
    • 27 Steimer, T., Driscoll, P., Inter-individual vs line/strain differences in psychogenetically selected Roman High-(RHA) and Low-(RLA) Avoidance rats: neuroendocrine and behavioural aspects. Neurosci Biobehav Rev 29 (2005), 99–112.
    • (2005) Neurosci Biobehav Rev , vol.29 , pp. 99-112
    • Steimer, T.1    Driscoll, P.2
  • 29
    • 33845347420 scopus 로고    scopus 로고
    • Altered brain activity processing in high-anxiety rodents revealed by challenge paradigms and functional mapping
    • 29 Singewald, N., Altered brain activity processing in high-anxiety rodents revealed by challenge paradigms and functional mapping. Neurosci Biobehav Rev 31 (2007), 18–40.
    • (2007) Neurosci Biobehav Rev , vol.31 , pp. 18-40
    • Singewald, N.1
  • 31
    • 84966397592 scopus 로고    scopus 로고
    • Genetic predisposition for high stress reactivity amplifies effects of early-life adversity
    • A recent paper showing in mice that genetic predisposition for high stress reactivity amplifies effects of early-life adversity supporting the idea that in individuals with a genetic risk factor for increased stress reactivity, early-life adversity can enhance the probability to develop psychopathology.
    • 31• McIlwrick, S., Rechenberg, A., Matthes, M., Burgstaller, J., Schwarzbauer, T., Chen, A., Touma, C., Genetic predisposition for high stress reactivity amplifies effects of early-life adversity. Psychoneuroendocrinology 70 (2016), 85–97 A recent paper showing in mice that genetic predisposition for high stress reactivity amplifies effects of early-life adversity supporting the idea that in individuals with a genetic risk factor for increased stress reactivity, early-life adversity can enhance the probability to develop psychopathology.
    • (2016) Psychoneuroendocrinology , vol.70 , pp. 85-97
    • McIlwrick, S.1    Rechenberg, A.2    Matthes, M.3    Burgstaller, J.4    Schwarzbauer, T.5    Chen, A.6    Touma, C.7
  • 32
    • 84883656565 scopus 로고    scopus 로고
    • The three-hit concept of vulnerability and resilience: toward understanding adaptation to early-life adversity outcome
    • 32 Daskalakis, N.P., Bagot, R.C., Parker, K.J., Vinkers, C.H., de Kloet, E.R., The three-hit concept of vulnerability and resilience: toward understanding adaptation to early-life adversity outcome. Psychoneuroendocrinology 38 (2013), 1858–1873.
    • (2013) Psychoneuroendocrinology , vol.38 , pp. 1858-1873
    • Daskalakis, N.P.1    Bagot, R.C.2    Parker, K.J.3    Vinkers, C.H.4    de Kloet, E.R.5
  • 33
    • 84940423321 scopus 로고    scopus 로고
    • Chronic stress and brain plasticity: mechanisms underlying adaptive and maladaptive changes and implications for stress-related CNS disorders
    • 33 Radley, J., Morilak, D., Viau, V., Campeau, S., Chronic stress and brain plasticity: mechanisms underlying adaptive and maladaptive changes and implications for stress-related CNS disorders. Neurosci Biobehav Rev 58 (2015), 79–91.
    • (2015) Neurosci Biobehav Rev , vol.58 , pp. 79-91
    • Radley, J.1    Morilak, D.2    Viau, V.3    Campeau, S.4
  • 34
    • 41849094793 scopus 로고    scopus 로고
    • Characterization of central and peripheral components of the hypothalamus-pituitary-adrenal axis in the inbred Roman rat strains
    • 34 Carrasco, J., Marquez, C., Nadal, R., Tobena, A., Fernandez-Teruel, A., Armario, A., Characterization of central and peripheral components of the hypothalamus-pituitary-adrenal axis in the inbred Roman rat strains. Psychoneuroendocrinology 33 (2008), 437–445.
    • (2008) Psychoneuroendocrinology , vol.33 , pp. 437-445
    • Carrasco, J.1    Marquez, C.2    Nadal, R.3    Tobena, A.4    Fernandez-Teruel, A.5    Armario, A.6
  • 35
    • 34249077219 scopus 로고    scopus 로고
    • Plasma corticosterone, dexamethasone (DEX) suppression and DEX/CRH tests in a rat model of genetic vulnerability to depression
    • 35 Steimer, T., Python, A., Schulz, P.E., Aubry, J.M., Plasma corticosterone, dexamethasone (DEX) suppression and DEX/CRH tests in a rat model of genetic vulnerability to depression. Psychoneuroendocrinology 32 (2007), 575–579.
    • (2007) Psychoneuroendocrinology , vol.32 , pp. 575-579
    • Steimer, T.1    Python, A.2    Schulz, P.E.3    Aubry, J.M.4
  • 38
    • 69949091530 scopus 로고    scopus 로고
    • Interaction of childhood maltreatment with the corticotropin-releasing hormone receptor gene: effects on hypothalamic-pituitary-adrenal axis reactivity
    • 38 Tyrka, A.R., Price, L.H., Gelernter, J., Schepker, C., Anderson, G.M., Carpenter, L.L., Interaction of childhood maltreatment with the corticotropin-releasing hormone receptor gene: effects on hypothalamic-pituitary-adrenal axis reactivity. Biol Psychiatry 66 (2009), 681–685.
    • (2009) Biol Psychiatry , vol.66 , pp. 681-685
    • Tyrka, A.R.1    Price, L.H.2    Gelernter, J.3    Schepker, C.4    Anderson, G.M.5    Carpenter, L.L.6
  • 40
    • 78049274861 scopus 로고    scopus 로고
    • Resilience to social stress coincides with functional DNA methylation of the Crf gene in adult mice
    • This paper demonstrates that social stress induced long-term demethylation of the CRF gene in susceptible individuals resulting in increased CRF expression, which is associated with an increase in depression-like behavior.
    • 40•• Elliott, E., Ezra-Nevo, G., Regev, L., Neufeld-Cohen, A., Chen, A., Resilience to social stress coincides with functional DNA methylation of the Crf gene in adult mice. Nat Neurosci 13 (2010), 1351–1353 This paper demonstrates that social stress induced long-term demethylation of the CRF gene in susceptible individuals resulting in increased CRF expression, which is associated with an increase in depression-like behavior.
    • (2010) Nat Neurosci , vol.13 , pp. 1351-1353
    • Elliott, E.1    Ezra-Nevo, G.2    Regev, L.3    Neufeld-Cohen, A.4    Chen, A.5
  • 41
    • 79958821386 scopus 로고    scopus 로고
    • Mechanisms of rapid glucocorticoid feedback inhibition of the hypothalamic-pituitary-adrenal axis
    • 41 Tasker, J.G., Herman, J.P., Mechanisms of rapid glucocorticoid feedback inhibition of the hypothalamic-pituitary-adrenal axis. Stress 14 (2011), 398–406.
    • (2011) Stress , vol.14 , pp. 398-406
    • Tasker, J.G.1    Herman, J.P.2
  • 42
    • 84871506427 scopus 로고    scopus 로고
    • Inhibitory function of the dorsomedial hypothalamic nucleus on the hypothalamic-pituitary-adrenal axis response to an emotional stressor but not immune challenge
    • 42 Ebner, K., Muigg, P., Singewald, N., Inhibitory function of the dorsomedial hypothalamic nucleus on the hypothalamic-pituitary-adrenal axis response to an emotional stressor but not immune challenge. J Neuroendocrinol 25 (2013), 48–55.
    • (2013) J Neuroendocrinol , vol.25 , pp. 48-55
    • Ebner, K.1    Muigg, P.2    Singewald, N.3
  • 43
    • 79951509897 scopus 로고    scopus 로고
    • The modulatory role of the lateral septum on neuroendocrine and behavioral stress responses
    • A paper from our group demonstrating selective involvement of the LS in inhibition of HPA axis stress responses and coping behavior.
    • 43• Singewald, G.M., Rjabokon, A., Singewald, N., Ebner, K., The modulatory role of the lateral septum on neuroendocrine and behavioral stress responses. Neuropsychopharmacology 36 (2011), 793–804 A paper from our group demonstrating selective involvement of the LS in inhibition of HPA axis stress responses and coping behavior.
    • (2011) Neuropsychopharmacology , vol.36 , pp. 793-804
    • Singewald, G.M.1    Rjabokon, A.2    Singewald, N.3    Ebner, K.4
  • 44
    • 2942527383 scopus 로고    scopus 로고
    • Expression of c-Fos-like immunoreactivity in the brain of mice with learned helplessness
    • 44 Huang, Y.H., Cheng, C.Y., Hong, C.J., Tsai, S.J., Expression of c-Fos-like immunoreactivity in the brain of mice with learned helplessness. Neurosci Lett 363 (2004), 280–283.
    • (2004) Neurosci Lett , vol.363 , pp. 280-283
    • Huang, Y.H.1    Cheng, C.Y.2    Hong, C.J.3    Tsai, S.J.4
  • 46
    • 84893452899 scopus 로고    scopus 로고
    • Control of stress-induced persistent anxiety by an extra-amygdala septohypothalamic circuit
    • This study uses circuit-specific optogenetics to confirm that increased phasic firing of LS cells identified as Crfr2 positive GABAergic projection neurons to the anterior hypothalamus enhanced stress-induced behavioral measures of anxiety.
    • 46•• Anthony, T.E., Dee, N., Bernard, A., Lerchner, W., Heintz, N., Anderson, D.J., Control of stress-induced persistent anxiety by an extra-amygdala septohypothalamic circuit. Cell 156 (2014), 522–536 This study uses circuit-specific optogenetics to confirm that increased phasic firing of LS cells identified as Crfr2 positive GABAergic projection neurons to the anterior hypothalamus enhanced stress-induced behavioral measures of anxiety.
    • (2014) Cell , vol.156 , pp. 522-536
    • Anthony, T.E.1    Dee, N.2    Bernard, A.3    Lerchner, W.4    Heintz, N.5    Anderson, D.J.6
  • 47
    • 84905226952 scopus 로고    scopus 로고
    • Prefrontal cortex reactivity underlies trait vulnerability to chronic social defeat stress
    • 47 Kumar, S., Hultman, R., Hughes, D., Michel, N., Katz, B.M., Dzirasa, K., Prefrontal cortex reactivity underlies trait vulnerability to chronic social defeat stress. Nat Commun, 5, 2014, 4537.
    • (2014) Nat Commun , vol.5 , pp. 4537
    • Kumar, S.1    Hultman, R.2    Hughes, D.3    Michel, N.4    Katz, B.M.5    Dzirasa, K.6
  • 48
    • 84992076935 scopus 로고    scopus 로고
    • Dysregulation of prefrontal cortex-mediated slow-evolving limbic dynamics drives stress-induced emotional pathology
    • 48 Hultman, R., Mague, S.D., Li, Q., Katz, B.M., Michel, N., Lin, L., Wang, J., David, L.K., Blount, C., Chandy, R., et al. Dysregulation of prefrontal cortex-mediated slow-evolving limbic dynamics drives stress-induced emotional pathology. Neuron 91 (2016), 439–452.
    • (2016) Neuron , vol.91 , pp. 439-452
    • Hultman, R.1    Mague, S.D.2    Li, Q.3    Katz, B.M.4    Michel, N.5    Lin, L.6    Wang, J.7    David, L.K.8    Blount, C.9    Chandy, R.10
  • 51
    • 3342989681 scopus 로고    scopus 로고
    • Epigenetic programming by maternal behavior
    • This important paper shows for the first time that the epigenomic state of the GR gene can be established by maternal behavior and further that this is potentially reversible.
    • 51•• Weaver, I.C., Cervoni, N., Champagne, F.A., D'Alessio, A.C., Sharma, S., Seckl, J.R., Dymov, S., Szyf, M., Meaney, M.J., Epigenetic programming by maternal behavior. Nat Neurosci 7 (2004), 847–854 This important paper shows for the first time that the epigenomic state of the GR gene can be established by maternal behavior and further that this is potentially reversible.
    • (2004) Nat Neurosci , vol.7 , pp. 847-854
    • Weaver, I.C.1    Cervoni, N.2    Champagne, F.A.3    D'Alessio, A.C.4    Sharma, S.5    Seckl, J.R.6    Dymov, S.7    Szyf, M.8    Meaney, M.J.9
  • 53
  • 54
    • 34248380127 scopus 로고    scopus 로고
    • Mineralocorticoid receptor overexpression in forebrain decreases anxiety-like behavior and alters the stress response in mice
    • 54 Rozeboom, A.M., Akil, H., Seasholtz, A.F., Mineralocorticoid receptor overexpression in forebrain decreases anxiety-like behavior and alters the stress response in mice. Proc Natl Acad Sci U S A 104 (2007), 4688–4693.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 4688-4693
    • Rozeboom, A.M.1    Akil, H.2    Seasholtz, A.F.3
  • 55
    • 84924452936 scopus 로고    scopus 로고
    • Mineralocorticoid receptor haplotypes sex-dependently moderate depression susceptibility following childhood maltreatment
    • 55 Vinkers, C.H., Joels, M., Milaneschi, Y., Gerritsen, L., Kahn, R.S., Penninx, B.W., Boks, M.P., Mineralocorticoid receptor haplotypes sex-dependently moderate depression susceptibility following childhood maltreatment. Psychoneuroendocrinology 54 (2015), 90–102.
    • (2015) Psychoneuroendocrinology , vol.54 , pp. 90-102
    • Vinkers, C.H.1    Joels, M.2    Milaneschi, Y.3    Gerritsen, L.4    Kahn, R.S.5    Penninx, B.W.6    Boks, M.P.7
  • 57
    • 84942475138 scopus 로고    scopus 로고
    • Stress and the brain: individual variability and the inverted-U
    • 57 Sapolsky, R.M., Stress and the brain: individual variability and the inverted-U. Nat Neurosci 18 (2015), 1344–1346.
    • (2015) Nat Neurosci , vol.18 , pp. 1344-1346
    • Sapolsky, R.M.1
  • 58
    • 84929864829 scopus 로고    scopus 로고
    • Mind the gap: glucocorticoids modulate hippocampal glutamate tone underlying individual differences in stress susceptibility
    • 58 Nasca, C., Bigio, B., Zelli, D., Nicoletti, F., McEwen, B.S., Mind the gap: glucocorticoids modulate hippocampal glutamate tone underlying individual differences in stress susceptibility. Mol Psychiatry 20 (2015), 755–763.
    • (2015) Mol Psychiatry , vol.20 , pp. 755-763
    • Nasca, C.1    Bigio, B.2    Zelli, D.3    Nicoletti, F.4    McEwen, B.S.5
  • 59
    • 70350731477 scopus 로고    scopus 로고
    • The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders
    • 59 Binder, E.B., The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders. Psychoneuroendocrinology 34:Suppl. 1 (2009), S186–S195.
    • (2009) Psychoneuroendocrinology , vol.34 , pp. S186-S195
    • Binder, E.B.1
  • 60
    • 84873743622 scopus 로고    scopus 로고
    • Glucocorticoid receptor and FKBP5 expression is altered following exposure to chronic stress: modulation by antidepressant treatment
    • 60 Guidotti, G., Calabrese, F., Anacker, C., Racagni, G., Pariante, C.M., Riva, M.A., Glucocorticoid receptor and FKBP5 expression is altered following exposure to chronic stress: modulation by antidepressant treatment. Neuropsychopharmacology 38 (2013), 616–627.
    • (2013) Neuropsychopharmacology , vol.38 , pp. 616-627
    • Guidotti, G.1    Calabrese, F.2    Anacker, C.3    Racagni, G.4    Pariante, C.M.5    Riva, M.A.6
  • 62
    • 80051941873 scopus 로고    scopus 로고
    • BDNF Val66Met polymorphism is associated with higher anticipatory cortisol stress response, anxiety, and alcohol consumption in healthy adults
    • 62 Colzato, L.S., Van der Does, A.J., Kouwenhoven, C., Elzinga, B.M., Hommel, B., BDNF Val66Met polymorphism is associated with higher anticipatory cortisol stress response, anxiety, and alcohol consumption in healthy adults. Psychoneuroendocrinology 36 (2011), 1562–1569.
    • (2011) Psychoneuroendocrinology , vol.36 , pp. 1562-1569
    • Colzato, L.S.1    Van der Does, A.J.2    Kouwenhoven, C.3    Elzinga, B.M.4    Hommel, B.5
  • 64
    • 84863380672 scopus 로고    scopus 로고
    • Variant brain-derived neurotrophic factor Val66Met polymorphism alters vulnerability to stress and response to antidepressants
    • 64 Yu, H., Wang, D.D., Wang, Y., Liu, T., Lee, F.S., Chen, Z.Y., Variant brain-derived neurotrophic factor Val66Met polymorphism alters vulnerability to stress and response to antidepressants. J Neurosci 32 (2012), 4092–4101.
    • (2012) J Neurosci , vol.32 , pp. 4092-4101
    • Yu, H.1    Wang, D.D.2    Wang, Y.3    Liu, T.4    Lee, F.S.5    Chen, Z.Y.6
  • 65
    • 84926052339 scopus 로고    scopus 로고
    • Epigenetic mechanisms underlying the role of brain-derived neurotrophic factor in depression and response to antidepressants
    • 65 Duclot, F., Kabbaj, M., Epigenetic mechanisms underlying the role of brain-derived neurotrophic factor in depression and response to antidepressants. J Exp Biol 218 (2015), 21–31.
    • (2015) J Exp Biol , vol.218 , pp. 21-31
    • Duclot, F.1    Kabbaj, M.2
  • 66
    • 84929647417 scopus 로고    scopus 로고
    • Regional differences in brain-derived neurotrophic factor levels and dendritic spine density confer resilience to inescapable stress
    • A paper that demonstrates in rats that regional differences in BDNF levels and spine density in the brain may contribute to susceptibility or resilience to inescapable stress.
    • 66• Yang, C., Shirayama, Y., Zhang, J.C., Ren, Q., Hashimoto, K., Regional differences in brain-derived neurotrophic factor levels and dendritic spine density confer resilience to inescapable stress. Int J Neuropsychopharmacol, 18, 2015, pyu121 A paper that demonstrates in rats that regional differences in BDNF levels and spine density in the brain may contribute to susceptibility or resilience to inescapable stress.
    • (2015) Int J Neuropsychopharmacol , vol.18 , pp. pyu121
    • Yang, C.1    Shirayama, Y.2    Zhang, J.C.3    Ren, Q.4    Hashimoto, K.5
  • 67
    • 72949096531 scopus 로고    scopus 로고
    • Knockdown of brain-derived neurotrophic factor in specific brain sites precipitates behaviors associated with depression and reduces neurogenesis
    • 67 Taliaz, D., Stall, N., Dar, D.E., Zangen, A., Knockdown of brain-derived neurotrophic factor in specific brain sites precipitates behaviors associated with depression and reduces neurogenesis. Mol Psychiatry 15 (2010), 80–92.
    • (2010) Mol Psychiatry , vol.15 , pp. 80-92
    • Taliaz, D.1    Stall, N.2    Dar, D.E.3    Zangen, A.4
  • 68
    • 79953008100 scopus 로고    scopus 로고
    • Resilience to chronic stress is mediated by hippocampal brain-derived neurotrophic factor
    • 68 Taliaz, D., Loya, A., Gersner, R., Haramati, S., Chen, A., Zangen, A., Resilience to chronic stress is mediated by hippocampal brain-derived neurotrophic factor. J Neurosci 31 (2011), 4475–4483.
    • (2011) J Neurosci , vol.31 , pp. 4475-4483
    • Taliaz, D.1    Loya, A.2    Gersner, R.3    Haramati, S.4    Chen, A.5    Zangen, A.6


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