Genetic predisposition for high stress reactivity amplifies effects of early-life adversity

Psychoneuroendocrinology

Volumn 70, Issue , 2016, Pages 85-97

  McIlwrick, Silja ^a,b   Rechenberg, Alexandra ^a   Matthes, Mariana ^a   Burgstaller, Jessica ^a   Schwarzbauer, Thomas ^a   Chen, Alon ^a,b,c   Touma, Chadi ^a,b  

^a MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Crh; Early life stress; Gene environment interaction; HPA axis; Major depressive disorder; Stress reactivity mouse model

Indexed keywords

CORTICOSTERONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY; ARTICLE; BEHAVIOR CHANGE; BODY TEMPERATURE; BRAIN DEVELOPMENT; BRAIN REGION; CONTROLLED STUDY; COPING BEHAVIOR; CORTICOSTERONE RELEASE; DOWN REGULATION; EARLY LIFE STRESS; EMOTIONALITY; ENVIRONMENTAL EXPOSURE; EPIGENETICS; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENETIC PREDISPOSITION; GENOTYPE ENVIRONMENT INTERACTION; HYPOPHYSIS ADRENAL SYSTEM; HYPOTHALAMUS HYPOPHYSIS SYSTEM; HYPOTHALAMUS PITUITARY ADRENOCORTICAL AXIS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; WEIGHT GAIN; ANIMAL; BRAIN; DISEASE MODEL; EMOTION; ENDOPHENOTYPE; GENETICS; MAJOR DEPRESSION; MENTAL STRESS; METABOLISM; MOOD DISORDER; NEUROSECRETION; PREGNANCY; RANDOMIZATION;

ADAPTATION, PSYCHOLOGICAL; ANIMALS; BRAIN; CORTICOSTERONE; DEPRESSIVE DISORDER, MAJOR; DISEASE MODELS, ANIMAL; EMOTIONS; ENDOPHENOTYPES; FEMALE; GENE-ENVIRONMENT INTERACTION; GENETIC PREDISPOSITION TO DISEASE; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; MALE; MICE; MOOD DISORDERS; NEUROSECRETORY SYSTEMS; PITUITARY-ADRENAL SYSTEM; PREGNANCY; RANDOM ALLOCATION; STRESS, PSYCHOLOGICAL;

EID: 84966397592     PISSN: 03064530     EISSN: 18733360     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2016.04.023     Document Type: Article

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