Anabolism-Associated Mitochondrial Stasis Driving Lymphocyte Differentiation over Self-Renewal

Cell Reports

Volumn 17, Issue 12, 2016, Pages 3142-3152

  Adams, William C ^a   Chen, Yen Hua ^a   Kratchmarov, Radomir ^a   Yen, Bonnie ^a   Nish, Simone A ^a   Lin, Wen Hsuan W ^a   Rothman, Nyanza J ^a   Luchsinger, Larry L ^a   Klein, Ulf ^a   Busslinger, Meinrad ^b   Rathmell, Jeffrey C ^c   Snoeck, Hans Willem ^a   Reiner, Steven L ^a  

^a NewYork Presbyterian Hospital   (United States)

^b RESEARCH INSTITUTE OF MOLECULAR PATHOLOGY   (Austria)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

asymmetric cell division; Pax5; self renewal; stem cell; TCF1; Warburg effect

Indexed keywords

ADENYLATE KINASE; INTERFERON REGULATORY FACTOR 4; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; TRANSCRIPTION FACTOR FKHR; FOXO1 PROTEIN, MOUSE; INTERFERON REGULATORY FACTOR; INTERFERON REGULATORY FACTOR-4; MTOR PROTEIN, MOUSE; REACTIVE OXYGEN METABOLITE; TARGET OF RAPAMYCIN KINASE;

AEROBIC GLYCOLYSIS; AEROBIC METABOLISM; ANIMAL CELL; ARTICLE; BIOSYNTHESIS; CATABOLISM; CELL FATE; CELL SELF-RENEWAL; CELLULAR, SUBCELLULAR AND MOLECULAR BIOLOGICAL PHENOMENA AND FUNCTIONS; CONTROLLED STUDY; ENZYME ACTIVATION; LYMPHOCYTE DIFFERENTIATION; MITOCHONDRIAL STASIS; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; ANIMAL; AUTOPHAGY; CELL DIFFERENTIATION; GENETICS; GLYCOLYSIS; HEMATOPOIESIS; LYMPHOCYTE; LYMPHOCYTE ACTIVATION; METABOLISM; MITOCHONDRION; REGENERATION;

ANIMALS; AUTOPHAGY; CELL DIFFERENTIATION; FORKHEAD BOX PROTEIN O1; GLYCOLYSIS; HEMATOPOIESIS; INTERFERON REGULATORY FACTORS; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; METABOLISM; MICE; MITOCHONDRIA; PHOSPHATIDYLINOSITOL 3-KINASES; REACTIVE OXYGEN SPECIES; REGENERATION; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 85006836447     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.11.065     Document Type: Article

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