메뉴 건너뛰기




Volumn 6, Issue , 2016, Pages

Liver Enzymes and Risk of Ischemic Heart Disease and Type 2 Diabetes Mellitus: A Mendelian Randomization Study

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; GAMMA GLUTAMYLTRANSFERASE;

EID: 85006778370     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep38813     Document Type: Article
Times cited : (48)

References (50)
  • 1
    • 36349033483 scopus 로고    scopus 로고
    • Gamma-glutamyltransferase is associated with incident vascular events independently of alcohol intake: Analysis of the British Women's Heart and Health Study and Meta-Analysis
    • Fraser, A. et al. Gamma-glutamyltransferase is associated with incident vascular events independently of alcohol intake: analysis of the British Women's Heart and Health Study and Meta-Analysis. Arteriosclerosis, thrombosis, and vascular biology 27, 2729-2735, doi: 10.1161/ATVBAHA.107.152298 (2007).
    • (2007) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.27 , pp. 2729-2735
    • Fraser, A.1
  • 2
    • 77956631214 scopus 로고    scopus 로고
    • Liver enzymes, nonalcoholic fatty liver disease, and incident cardiovascular disease: A narrative review and clinical perspective of prospective data
    • Ghouri, N., Preiss, D. & Sattar, N. Liver enzymes, nonalcoholic fatty liver disease, and incident cardiovascular disease: a narrative review and clinical perspective of prospective data. Hepatology (Baltimore, Md.) 52, 1156-1161, doi: 10.1002/hep.23789 (2010).
    • (2010) Hepatology (Baltimore, Md.) , vol.52 , pp. 1156-1161
    • Ghouri, N.1    Preiss, D.2    Sattar, N.3
  • 3
    • 84908270441 scopus 로고    scopus 로고
    • Gamma-glutamyl transferase and risk of type II diabetes: An updated systematic review and dose-response meta-analysis
    • Kunutsor, S. K., Abbasi, A. & Adler, A. I. Gamma-glutamyl transferase and risk of type II diabetes: an updated systematic review and dose-response meta-analysis. Annals of epidemiology 24, 809-816, doi: 10.1016/j.annepidem.2014.09.001 (2014).
    • (2014) Annals of Epidemiology , vol.24 , pp. 809-816
    • Kunutsor, S.K.1    Abbasi, A.2    Adler, A.I.3
  • 4
    • 84946576411 scopus 로고    scopus 로고
    • Liver enzymes and incident diabetes in China: A prospective analysis of 10 764 participants in the Guangzhou Biobank Cohort Study
    • Xu, L. et al. Liver enzymes and incident diabetes in China: a prospective analysis of 10 764 participants in the Guangzhou Biobank Cohort Study. Journal of epidemiology and community health 69, 1040-1044, doi: 10.1136/jech-2015-205518 (2015).
    • (2015) Journal of Epidemiology and Community Health , vol.69 , pp. 1040-1044
    • Xu, L.1
  • 5
    • 7044274423 scopus 로고    scopus 로고
    • Elevated alanine aminotransferase predicts new-onset type 2 diabetes independently of classical risk factors, metabolic syndrome, and C-reactive protein in the west of Scotland coronary prevention study
    • Sattar, N. et al. Elevated alanine aminotransferase predicts new-onset type 2 diabetes independently of classical risk factors, metabolic syndrome, and C-reactive protein in the west of Scotland coronary prevention study. Diabetes 53, 2855-2860 (2004).
    • (2004) Diabetes , vol.53 , pp. 2855-2860
    • Sattar, N.1
  • 6
    • 83455169015 scopus 로고    scopus 로고
    • The inverse relationship between alanine aminotransferase in the normal range and adverse cardiovascular and noncardiovascular outcomes
    • Ford, I. et al. The inverse relationship between alanine aminotransferase in the normal range and adverse cardiovascular and noncardiovascular outcomes. International journal of epidemiology 40, 1530-1538, doi: 10.1093/ije/dyr172 (2011).
    • (2011) International Journal of Epidemiology , vol.40 , pp. 1530-1538
    • Ford, I.1
  • 7
    • 58649083017 scopus 로고    scopus 로고
    • Elevated serum alanine aminotransferase and gamma-glutamyltransferase and mortality in the United States population
    • Ruhl, C. E. & Everhart, J. E. Elevated serum alanine aminotransferase and gamma-glutamyltransferase and mortality in the United States population. Gastroenterology 136, 477-485 e411, doi: 10.1053/j.gastro.2008.10.052 (2009).
    • (2009) Gastroenterology , vol.136 , pp. 477-485e411
    • Ruhl, C.E.1    Everhart, J.E.2
  • 8
    • 84940771387 scopus 로고    scopus 로고
    • Serum alkaline phosphatase and risk of incident cardiovascular disease: Interrelationship with high sensitivity C-reactive protein
    • Kunutsor, S. K. et al. Serum Alkaline Phosphatase and Risk of Incident Cardiovascular Disease: Interrelationship with High Sensitivity C-Reactive Protein. PloS one 10, e0132822, doi: 10.1371/journal.pone.0132822 (2015).
    • (2015) PloS One , vol.10
    • Kunutsor, S.K.1
  • 10
    • 40849083720 scopus 로고    scopus 로고
    • Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology
    • Lawlor, D. A., Harbord, R. M., Sterne, J. A., Timpson, N. & Davey Smith, G. Mendelian randomization: using genes as instruments for making causal inferences in epidemiology. Statistics in medicine 27, 1133-1163, doi: 10.1002/sim.3034 (2008).
    • (2008) Statistics in Medicine , vol.27 , pp. 1133-1163
    • Lawlor, D.A.1    Harbord, R.M.2    Sterne, J.A.3    Timpson, N.4    Davey Smith, G.5
  • 11
    • 0017350223 scopus 로고
    • Elevation of serum alkaline phosphatase activity and related enzymes in diabetes mellitus
    • Goldberg, D. M., Martin, J. V. & Knight, A. H. Elevation of serum alkaline phosphatase activity and related enzymes in diabetes mellitus. Clinical biochemistry 10, 8-11 (1977).
    • (1977) Clinical Biochemistry , vol.10 , pp. 8-11
    • Goldberg, D.M.1    Martin, J.V.2    Knight, A.H.3
  • 12
    • 79953204259 scopus 로고    scopus 로고
    • Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
    • Schunkert, H. et al. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nature genetics 43, 333-338, doi: 10.1038/ng.784 (2011).
    • (2011) Nature Genetics , vol.43 , pp. 333-338
    • Schunkert, H.1
  • 13
    • 79953221100 scopus 로고    scopus 로고
    • A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease
    • The Coronary Artery Disease (C4D) Genetics Consortium
    • The Coronary Artery Disease (C4D) Genetics Consortium. A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease. Nature genetics 43, 339-344, doi: 10.1038/ng.782 (2011).
    • (2011) Nature Genetics , vol.43 , pp. 339-344
  • 14
    • 84871969762 scopus 로고    scopus 로고
    • Large-scale association analysis identifies new risk loci for coronary artery disease
    • The CARDIoGRAMplusC4D Consortium.
    • The CARDIoGRAMplusC4D Consortium. Large-scale association analysis identifies new risk loci for coronary artery disease. Nature genetics 45, 25-33, doi: 10.1038/ng.2480 (2013).
    • (2013) Nature Genetics , vol.45 , pp. 25-33
  • 15
    • 84868337361 scopus 로고    scopus 로고
    • Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
    • Morris, A. P. et al. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nature genetics 44, 981-990, doi: 10.1038/ng.2383 (2012).
    • (2012) Nature Genetics , vol.44 , pp. 981-990
    • Morris, A.P.1
  • 16
    • 84887099827 scopus 로고    scopus 로고
    • Discovery and refinement of loci associated with lipid levels
    • Global Lipids Genetics, C.
    • Global Lipids Genetics, C. Discovery and refinement of loci associated with lipid levels. Nature genetics 45, 1274-1283, doi: 10.1038/ng.2797 http://www.nature.com/ng/journal/v45/n11/abs/ng.2797.html#supplementary-information (2013).
    • (2013) Nature Genetics , vol.45 , pp. 1274-1283
  • 17
    • 75749086085 scopus 로고    scopus 로고
    • New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
    • Dupuis, J. et al. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nature genetics 42, 105-116, doi: 10.1038/ng.520 (2010).
    • (2010) Nature Genetics , vol.42 , pp. 105-116
    • Dupuis, J.1
  • 18
    • 80055024880 scopus 로고    scopus 로고
    • Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma
    • Chambers, J. C. et al. Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nature genetics 43, 1131-1138, doi: 10.1038/ng.970 (2011).
    • (2011) Nature Genetics , vol.43 , pp. 1131-1138
    • Chambers, J.C.1
  • 19
    • 57349163062 scopus 로고    scopus 로고
    • Aminotransferase levels and 20-year risk of metabolic syndrome, diabetes, and cardiovascular disease
    • 1944 e1931
    • Goessling, W. et al. Aminotransferase levels and 20-year risk of metabolic syndrome, diabetes, and cardiovascular disease. Gastroenterology 135, 1935-1944, 1944 e1931, doi: 10.1053/j.gastro.2008.09.018 (2008).
    • (2008) Gastroenterology , vol.135 , pp. 1935-1944
    • Goessling, W.1
  • 20
    • 84896722557 scopus 로고    scopus 로고
    • Mendelian randomization in health research: Using appropriate genetic variants and avoiding biased estimates
    • Taylor, A. E. et al. Mendelian randomization in health research: using appropriate genetic variants and avoiding biased estimates. Economics and human biology 13, 99-106, doi: 10.1016/j.ehb.2013.12.002 (2014).
    • (2014) Economics and Human Biology , vol.13 , pp. 99-106
    • Taylor, A.E.1
  • 21
    • 0032714352 scopus 로고    scopus 로고
    • Genomic control for association studies
    • Devlin, B. & Roeder, K. Genomic control for association studies. Biometrics 55, 997-1004 (1999).
    • (1999) Biometrics , vol.55 , pp. 997-1004
    • Devlin, B.1    Roeder, K.2
  • 22
    • 84942987885 scopus 로고    scopus 로고
    • A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease
    • Nikpay, M. et al. A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease. Nature genetics 47, 1121-1130, doi: 10.1038/ng.3396 (2015).
    • (2015) Nature Genetics , vol.47 , pp. 1121-1130
    • Nikpay, M.1
  • 23
    • 78649461131 scopus 로고    scopus 로고
    • Common variants at 10 genomic loci influence hemoglobin A(1)(C) levels via glycemic and nonglycemic pathways
    • Soranzo, N. et al. Common variants at 10 genomic loci influence hemoglobin A(1)(C) levels via glycemic and nonglycemic pathways. Diabetes 59, 3229-3239, doi: 10.2337/db10-0502 (2010).
    • (2010) Diabetes , vol.59 , pp. 3229-3239
    • Soranzo, N.1
  • 24
    • 84979576912 scopus 로고    scopus 로고
    • Sensitivity analyses for robust causal inference from Mendelian randomization analyses with multiple genetic variants
    • (Cambridge, Mass.)
    • Burgess, S., Bowden, J., Fall, T., Ingelsson, E. & Thompson, S. G. Sensitivity analyses for robust causal inference from Mendelian randomization analyses with multiple genetic variants. Epidemiology (Cambridge, Mass.) (2016).
    • (2016) Epidemiology
    • Burgess, S.1    Bowden, J.2    Fall, T.3    Ingelsson, E.4    Thompson, S.G.5
  • 26
    • 84920269464 scopus 로고    scopus 로고
    • Proteomics.Tissue-based map of the human proteome
    • Uhlen, M. et al. Proteomics. Tissue-based map of the human proteome. Science (New York, N.Y.) 347, 1260419, doi: 10.1126/science.1260419 (2015).
    • (2015) Science (New York, N.Y.) , vol.347 , pp. 1260419
    • Uhlen, M.1
  • 29
    • 84868206437 scopus 로고    scopus 로고
    • Alanine transaminase has opposite associations with death from diabetes and ischemic heart disease in NHANES III
    • Schooling, C. M., Kelvin, E. A. & Jones, H. E. Alanine transaminase has opposite associations with death from diabetes and ischemic heart disease in NHANES III. Annals of epidemiology 22, 789-798, doi: 10.1016/j.annepidem.2012.08.003 (2012).
    • (2012) Annals of Epidemiology , vol.22 , pp. 789-798
    • Schooling, C.M.1    Kelvin, E.A.2    Jones, H.E.3
  • 30
    • 79959365503 scopus 로고    scopus 로고
    • The association between the metabolic syndrome and alanine amino transferase is mediated by insulin resistance via related metabolic intermediates (the Cohort on Diabetes and Atherosclerosis Maastricht [CODAM] study)
    • Jacobs, M. et al. The association between the metabolic syndrome and alanine amino transferase is mediated by insulin resistance via related metabolic intermediates (the Cohort on Diabetes and Atherosclerosis Maastricht [CODAM] study). Metabolism: clinical and experimental 60, 969-975, doi: 10.1016/j.metabol.2010.09.006 (2011).
    • (2011) Metabolism: Clinical and Experimental , vol.60 , pp. 969-975
    • Jacobs, M.1
  • 33
    • 84946509188 scopus 로고    scopus 로고
    • Using genetic variants to assess the relationship between circulating lipids and type 2 diabetes
    • Fall, T. et al. Using Genetic Variants to Assess the Relationship Between Circulating Lipids and Type 2 Diabetes. Diabetes 64, 2676-2684, doi: 10.2337/db14-1710 (2015).
    • (2015) Diabetes , vol.64 , pp. 2676-2684
    • Fall, T.1
  • 34
    • 84921493092 scopus 로고    scopus 로고
    • HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: Evidence from genetic analysis and randomised trials
    • Swerdlow, D. I. et al. HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials. Lancet (London, England) 385, 351-361, doi: 10.1016/S0140-6736(14)61183-1 (2015).
    • (2015) Lancet (London, England) , vol.385 , pp. 351-361
    • Swerdlow, D.I.1
  • 35
    • 84924358878 scopus 로고    scopus 로고
    • Association between familial hypercholesterolemia and prevalence of type 2 diabetes mellitus
    • Besseling, J., Kastelein, J. J., Defesche, J. C., Hutten, B. A. & Hovingh, G. K. Association between familial hypercholesterolemia and prevalence of type 2 diabetes mellitus. Jama 313, 1029-1036, doi: 10.1001/jama.2015.1206 (2015).
    • (2015) Jama , vol.313 , pp. 1029-1036
    • Besseling, J.1    Kastelein, J.J.2    Defesche, J.C.3    Hutten, B.A.4    Hovingh, G.K.5
  • 36
    • 84925341298 scopus 로고    scopus 로고
    • Why do statins reduce cardiovascular disease more than other lipid modulating therapies?
    • Schooling, C. M., Au Yeung, S. L. & Leung, G. M. Why do statins reduce cardiovascular disease more than other lipid modulating therapies? European journal of clinical investigation 44, 1135-1140, doi: 10.1111/eci.12342 (2014).
    • (2014) European Journal of Clinical Investigation , vol.44 , pp. 1135-1140
    • Schooling, C.M.1    Au Yeung, S.L.2    Leung, G.M.3
  • 37
    • 0033819596 scopus 로고    scopus 로고
    • Localization of androgen and estrogen receptors in rat and primate tissues
    • Pelletier, G. Localization of androgen and estrogen receptors in rat and primate tissues. Histology and histopathology 15, 1261-1270 (2000).
    • (2000) Histology and Histopathology , vol.15 , pp. 1261-1270
    • Pelletier, G.1
  • 38
    • 23844494772 scopus 로고    scopus 로고
    • Cytochrome P450-mediated metabolism of estrogens and its regulation in human
    • Tsuchiya, Y., Nakajima, M. & Yokoi, T. Cytochrome P450-mediated metabolism of estrogens and its regulation in human. Cancer letters 227, 115-124, doi: 10.1016/j.canlet.2004.10.007 (2005).
    • (2005) Cancer Letters , vol.227 , pp. 115-124
    • Tsuchiya, Y.1    Nakajima, M.2    Yokoi, T.3
  • 39
    • 43849084078 scopus 로고    scopus 로고
    • Inactivation by UDP-glucuronosyltransferase enzymes: The end of androgen signaling
    • Chouinard, S. et al. Inactivation by UDP-glucuronosyltransferase enzymes: the end of androgen signaling. The Journal of steroid biochemistry and molecular biology 109, 247-253, doi: 10.1016/j.jsbmb.2008.03.016 (2008).
    • (2008) The Journal of Steroid Biochemistry and Molecular Biology , vol.109 , pp. 247-253
    • Chouinard, S.1
  • 41
    • 4143116880 scopus 로고    scopus 로고
    • Effect of oestrogen plus progestin on the incidence of diabetes in postmenopausal women: Results from the Women's Health Initiative Hormone Trial
    • Margolis, K. L. et al. Effect of oestrogen plus progestin on the incidence of diabetes in postmenopausal women: results from the Women's Health Initiative Hormone Trial. Diabetologia 47, 1175-1187, doi: 10.1007/s00125-004-1448-x (2004).
    • (2004) Diabetologia , vol.47 , pp. 1175-1187
    • Margolis, K.L.1
  • 42
    • 84924748127 scopus 로고    scopus 로고
    • Adolescent testosterone, muscle mass and glucose metabolism: Evidence from the 'Children of 1997' birth cohort in Hong Kong
    • Hou, W. W., Tse, M. A., Lam, T. H., Leung, G. M. & Schooling, C. M. Adolescent testosterone, muscle mass and glucose metabolism: evidence from the 'Children of 1997' birth cohort in Hong Kong. Diabetic medicine: a journal of the British Diabetic Association 32, 505-512, doi: 10.1111/dme.12602 (2015).
    • (2015) Diabetic Medicine: A Journal of the British Diabetic Association , vol.32 , pp. 505-512
    • Hou, W.W.1    Tse, M.A.2    Lam, T.H.3    Leung, G.M.4    Schooling, C.M.5
  • 43
    • 84940105378 scopus 로고    scopus 로고
    • Effects of testosterone treatment on glucose metabolism and symptoms in men with type 2 diabetes and the metabolic syndrome: A systematic review and meta-analysis of randomized controlled clinical trials
    • Grossmann, M., Hoermann, R., Wittert, G. & Yeap, B. B. Effects of testosterone treatment on glucose metabolism and symptoms in men with type 2 diabetes and the metabolic syndrome: a systematic review and meta-analysis of randomized controlled clinical trials. Clinical endocrinology 83, 344-351, doi: 10.1111/cen.12664 (2015).
    • (2015) Clinical Endocrinology , vol.83 , pp. 344-351
    • Grossmann, M.1    Hoermann, R.2    Wittert, G.3    Yeap, B.B.4
  • 45
    • 84924981752 scopus 로고    scopus 로고
    • Statin intolerance-an attempt at a unified definition. Position paper from an International Lipid Expert Panel
    • Banach, M. et al. Statin intolerance-an attempt at a unified definition. Position paper from an International Lipid Expert Panel. Archives of medical science: AMS 11, 1-23, doi: 10.5114/aoms.2015.49807 (2015).
    • (2015) Archives of Medical Science: AMS , vol.11 , pp. 1-23
    • Banach, M.1
  • 46
    • 84874372959 scopus 로고    scopus 로고
    • The effect of statins on testosterone in men and women, a systematic review and meta-analysis of randomized controlled trials
    • Schooling, C. M., Au Yeung, S. L., Freeman, G. & Cowling, B. J. The effect of statins on testosterone in men and women, a systematic review and meta-analysis of randomized controlled trials. BMC medicine 11, 57, doi: 10.1186/1741-7015-11-57 (2013).
    • (2013) BMC Medicine , vol.11 , pp. 57
    • Schooling, C.M.1    Au Yeung, S.L.2    Freeman, G.3    Cowling, B.J.4
  • 47
    • 0001294645 scopus 로고
    • The Fitting of Straight Lines if Both Variables are Subject to Error
    • Wald, A. The Fitting of Straight Lines if Both Variables are Subject to Error. The Annals of Mathematical Statistics 11, 284-300, doi: 10.1214/aoms/1177731868 (1940).
    • (1940) The Annals of Mathematical Statistics , vol.11 , pp. 284-300
    • Wald, A.1
  • 49
    • 84943354221 scopus 로고    scopus 로고
    • Using published data in Mendelian randomization: A blueprint for efficient identification of causal risk factors
    • Burgess, S. et al. Using published data in Mendelian randomization: a blueprint for efficient identification of causal risk factors. European journal of epidemiology 30, 543-552, doi: 10.1007/s10654-015-0011-z (2015).
    • (2015) European Journal of Epidemiology , vol.30 , pp. 543-552
    • Burgess, S.1
  • 50
    • 84963670568 scopus 로고    scopus 로고
    • Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator
    • Bowden, J., Davey Smith, G., Haycock, P. C. & Burgess, S. Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator. Genet Epidemiol 40, 304-314, doi: 10.1002/gepi.21965 (2016).
    • (2016) Genet Epidemiol , vol.40 , pp. 304-314
    • Bowden, J.1    Davey Smith, G.2    Haycock, P.C.3    Burgess, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.