CD8+ T Cells Utilize Highly Dynamic Enhancer Repertoires and Regulatory Circuitry in Response to Infections

Immunity

Volumn 45, Issue 6, 2016, Pages 1341-1354

  He, Bing ^a   Xing, Shaojun ^b   Chen, Changya ^c   Gao, Peng ^a   Teng, Li ^e   Shan, Qiang ^b   Gullicksrud, Jodi A ^b,c   Martin, Matthew D ^b,c   Yu, Shuyang ^f   Harty, John T ^b,c   Badovinac, Vladimir P ^b,c   Tan, Kai ^a,d   Xue, Hai Hui ^b,c,d  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c UNIVERSITY OF IOWA   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e ILLUMINA INC   (United States)

^f CHINA AGRICULTURAL UNIVERSITY   (China)

Author keywords

CD8 T cells; Central memory; Effector CD8 T cells; Enhancer promoter interactome; Enhancers; Epigenetics; Hi C; Na ve CD8 T cells; Super enhancers; Transcriptional regulatory network

Indexed keywords

HISTONE; TRANSCRIPTION FACTOR;

ALGORITHM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD8+ T LYMPHOCYTE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ENHANCER REGION; EPIGENETICS; GENE EXPRESSION; GENE REGULATORY NETWORK; GENE SEQUENCE; HISTONE MODIFICATION; IMMUNE RESPONSE; INFECTION; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MEMORY; MEMORY T LYMPHOCYTE; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN MOTIF; TRANSCRIPTION REGULATION; TRANSCRIPTOMICS; VIRUS INFECTION; ANIMAL; ARENAVIRUS INFECTION; BIOLOGY; CELL DIFFERENTIATION; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; HIGH THROUGHPUT SEQUENCING; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; PROCEDURES;

ALGORITHMS; ANIMALS; ARENAVIRIDAE INFECTIONS; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CHROMATIN IMMUNOPRECIPITATION; COMPUTATIONAL BIOLOGY; DISEASE MODELS, ANIMAL; ENHANCER ELEMENTS, GENETIC; EPIGENOMICS; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; LYMPHOCYTE ACTIVATION; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MICE; PROMOTER REGIONS, GENETIC;

EID: 85006701206     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2016.11.009     Document Type: Article

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