Tcf1 and Lef1 transcription factors establish CD8+ T cell identity through intrinsic HDAC activity

Nature Immunology

Volumn 17, Issue 6, 2016, Pages 695-703

  Xing, Shaojun ^a   Li, Fengyin ^a   Zeng, Zhouhao ^b   Zhao, Yunjie ^b   Yu, Shuyang ^c   Shan, Qiang ^a   Li, Yalan ^d   Phillips, Farrah C ^a,d,f   Maina, Peterson K ^a   Qi, Hank H ^a   Liu, Chengyu ^e   Zhu, Jun ^e   Pope, R Marshall ^d   Musselman, Catherine A ^a   Zeng, Chen ^b   Peng, Weiqun ^b   Xue, Hai Hui ^a,d  

^a UNIVERSITY OF IOWA   (United States)

^b GEORGE WASHINGTON UNIVERSITY   (United States)

^c CHINA AGRICULTURAL UNIVERSITY   (China)

^d UNIVERSITY OF IOWA   (United States)

^e NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^f ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CD4 ANTIGEN; CD40 LIGAND; GRANZYME B; HISTONE DEACETYLASE; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 6; HISTONE DEACETYLASE INHIBITOR; HISTONE H3; LYMPHOID ENHANCER FACTOR 1; PERFORIN; RETINOID RELATED ORPHAN RECEPTOR GAMMA; TRANSCRIPTION FACTOR 7; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR GATA 3; HEPATOCYTE NUCLEAR FACTOR 1ALPHA; HNF1A PROTEIN, MOUSE; LEF1 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; BINDING SITE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL MATURATION; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOTOXICITY; DEACETYLATION; ENZYME ACTIVITY; FEMALE; GENE LOCUS; GENE MUTATION; GENE REPRESSION; GENE SILENCING; HIGH THROUGHPUT SEQUENCING; HISTONE ACETYLATION; HISTONE MODIFICATION; INTRON; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; THYMOCYTE; TRANSCRIPTION INITIATION SITE; ACETYLATION; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL DIFFERENTIATION; CELL LINEAGE; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; MUTATION; PROTEIN DOMAIN;

ACETYLATION; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELL LINEAGE; CELLS, CULTURED; FEMALE; GENE EXPRESSION REGULATION; HEPATOCYTE NUCLEAR FACTOR 1-ALPHA; HISTONE DEACETYLASES; LYMPHOID ENHANCER-BINDING FACTOR 1; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUTATION; PROTEIN DOMAINS;

EID: 84964253526     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3456     Document Type: Article

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