The human gastric microbiota: Is it time to rethink the pathogenesis of stomach diseases?

United European Gastroenterology Journal

Volumn 3, Issue 3, 2015, Pages 255-260

  Nardone, Gerardo ^a   Compare, Debora ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Gastric cancer; Gastric microbiota; Gastritis; Helicobacter pylori; Review; Stomach bacteria; Stomach cancer

Indexed keywords

OMEPRAZOLE; PEPSINOGEN I; PEPSINOGEN II;

ACTINOBACTERIA; CLOSTRIDIUM; DENATURING GRADIENT GEL ELECTROPHORESIS; FIRMICUTES; FUSOBACTERIA; HAEMOPHILUS; HELICOBACTER INFECTION; HUMAN; LACTOBACILLUS; MICROFLORA; NONHUMAN; PEPTIC ULCER; PREVOTELLA; PRIORITY JOURNAL; PROPIONIBACTERIUM; PROTEOBACTERIA; REVIEW; ROTHIA; STOMACH CANCER; STOMACH DISEASE; STREPTOCOCCUS; SYSTEMATIC REVIEW; VEILLONELLA;

EID: 85006216356     PISSN: 20506406     EISSN: 20506414     Source Type: Journal    
DOI: 10.1177/2050640614566846     Document Type: Review

References (45)

1. Abdo Z, Schuette UM, Bent SJ, et al. Statistical methods for characterizing diversity of microbial communities by analysis of terminal restriction fragment length polymorphisms of 16S rRNA genes. Environ Microbiol 2006; 8: 929–938.
2. Lederberg J. Infectious history. Science 2000; 288: 287–293.
3. Turnbaugh PJ, Ley RE, Hamady M, et al. The human microbiome project. Nature 2007; 449: 804–810.
4. Wang ZK and Yang YS. Upper gastrointestinal microbiota and digestive diseases. World J Gastroenterol 2013; 19: 1541–1550.
5. Peterson J, Garges S, Giovanni M, et al. The NIH Human Microbiome Project. Genome Res 2009; 19: 2317–2323.
6. Yang I, Nell S and Suerbaum S. Survival in hostile territory: The microbiota of the stomach. FEMS Microbiol Rev 2013; 37: 736–761.
7. Wu WM, Yang YS and Peng LH. Microbiota in the stomach: New insights. J Dig Dis 2014; 15: 54–61.
8. Kazor CE, Mitchell PM, Lee AM, et al. Diversity of bacterial populations on the tongue dorsa of patients with halitosis and healthy patients. J Clin Microbiol 2003; 41: 558–563.
9. Zilberstein B, Quintanilha AG, Santos MA, et al. Digestive tract microbiota in healthy volunteers. Clinics 2007; 62: 47–54.
10. Bik EM, Eckburg PB, Gill SR, et al. Molecular analysis of the bacterial microbiota in the human stomach. Proc Natl Acad Sci USA 2006; 103: 732–737.
11. Azcarate-Peril MA, Sikes Mand, Bruno-Barcena JM. Theintestinal microbiota, gastrointestinal environment and colorectal cancer: A putative role for probiotics in prevention of colorectal cancer? Am J Physiol Gastrointest Liver Physiol 2011; 301: g401–g424.
12. Eckburg PB, Bik EM, Bernstein CN, et al. Diversity of the human intestinal microbial flora. Science 2005; 308: 1635–1638.
13. Fraher MH, O’Toole PW and Quigley EM. Techniques used to characterize the gut microbiota: A guide for the clinician. Nat Rev Gastroenterol Hepatol 2012; 9: B312–B322.
14. Li XX, Wong GL, To KF, et al. Bacterial microbiota profiling in gastritis without Helicobacter pylori infection or non–steroidal anti-inflammatory drug use. PLoS One 2009; 4: e7985.
15. Engstrand L and Lindberg M. Helicobacter pylori and the gastric microbiota. Best Pract Res Clin Gastroenterol 2013; 27: 39–45.
16. Delgado S, Cabrera-Rubio R, Mira A, et al. Microbiological survey of the human gastric ecosystem using culturing and pyrosequencing methods. Microb Ecol 2013; 65: 763–772.
17. Goldsmith JR and Sartor RB. The role of diet on intestinal microbiota metabolism: Downstream impacts on host immune function and health, and therapeutic implications. J Gastroenterol 2014; 49: 785–798.
18. Korpela K, Flint HJ, Johnstone AM, et al. Gut microbiota signatures predict host and microbiota responses to dietary interventions in obese individuals. PLoS One 2014; 9: e90702.
19. David LA, Maurice CF, Carmody RN, et al. Diet rapidly and reproducibly alters the human gut microbiome. Nature 2014; 505: 559–563.
20. Chan YK, Estaki M and Gibson DL. Clinical consequences of diet-induced dysbiosis. Ann Nutr Metab 2013; 63: 28–40.
21. Fan W, Huo G, Li X, et al. Impact of diet in shaping gut microbiota revealed by a comparative study in infants during the six months of life. J Microbiol Biotechnol 2014; 24: 133–143.
22. Sahasakul Y, Takemura N and Sonoyama K. Different impacts of purified and nonpurified diets on microbiota and toll-like receptors in the mouse stomach. Biosci Biotechnol Biochem 2012; 76: 1728–1732.
23. Vesper BJ, Jawdi A, Altman KW, et al. The effect of proton pump inhibitors on the human microbiota. Curr Drug Metab 2009; 10: 84–89.
24. Sanduleanu S, Jonkers D, De Bruine A, et al. Non-Helicobacter pylori bacterial flora during acid-suppressive therapy: Differential findings in gastric juice and gastric mucosa. Aliment Pharmacol Ther 2001; 15: 379–388.
25. Theisen J, Nehra D, Citron D, et al. Suppression of gastric acid secretion in patients with gastroesophageal reflux disease results in gastric bacterial overgrowth and deconjugation of bile acids. J Gastrointest Sur 2000; 4: 50–54.
26. Mason KL, Erb Downward JR, Falkowski NR, et al. Interplay between the gastric bacterial microbiota and Candida albicans during postantibiotic recolonization and gastritis. Infect Immun 2012; 80: 150–158.
27. Osaki T, Matsuki T, Asahara T, et al. Comparative analysis of gastric bacterial microbiota in Mongolian gerbils after long-term infection with Helicobacter pylori. Microb Pathog 2012; 53: 12–18.
28. Maldonado-Contreras A, Goldfarb KC, Godoy-Vitorino F, et al. Structure of the human gastric bacterial community in relation to Helicobacter pylori status. ISME J 2011; 5: 574–579.
29. Tan MP, Kaparakis M, Galic M, et al. Chronic Helicobacter pylori infection does not significantly alter the microbiota of the murine stomach. Appl Environ Microbiol 2007; 73: 1010–1013.
30. Khosravi Y, Dieye Y, Poh BH, et al. Culturable bacterial microbiota of the stomach of Helicobacter pylori positive and negative gastric disease patients. Scientif World J 2014; 610-421.
31. Walker MM and Talley NJ. Bacteria and pathogenesis of disease in the upper gastrointestinal tract: Beyond the era of Helicobacter pylori. Aliment Pharmacol Ther 2014; 39: 767–779.
32. Aviles-Jimenez F, Vazquez-Jimenez F, Medrano-Guzman R, et al. Stomach microbiota composition varies between patients with non-atrophic gastritis and patients with intestinal type of gastric cancer. Sci Rep 2014; 4: 4202.
33. Sheh A and Fox JG. The role of the gastrointestinal microbiome in Helicobacter pylori pathogenesis. Gut Microbe 2013; 4: 505–531.
34. Martin M and Solnick JV. The gastric microbial community, Helicobacter pylori colonization, and disease. Gut Microbe 2014; 5: 345–350.
35. Rolig AS, Cech C, Ahler E, et al. The degree of Helicobacter pylori-triggered inflammation is manipulated by preinfection host microbiota. Infect Immun 2013; 81: 1382–1389.
36. Lofgren JL, Whary MT, Ge Z, et al. Lack of commensal flora in Helicobacter pylori-infected INS-GAS mice reduces gastritis and delays intraepithelial neoplasia. Gastroenterology 2011; 140: 210–220.
37. Lertpiriyapong K, Whary MT, Muthupalani S, et al. Gastric colonisation with a restricted commensal microbiota replicates the promotion of neoplastic lesions by diverse intestinal microbiota in the Helicobacter pylori INS-GAS mouse model of gastric carcinogenesis. Gut 2014; 63: 54–63.
38. Lee CW, Rickman B, Rogers AB, et al. Combination of sulindac and antimicrobial eradication of Helicobacter pylori prevents progression of gastric cancer in hypergastrinemic INS-GAS mice. Cancer Res 2009; 69: 8166–8174.
39. Hu Y, He LH, Xiao D, et al. Bacterial flora concurrent with Helicobacter pylori in the stomach of patients with upper gastrointestinal diseases. World J Gastroenterol 2012; 18: 1257–1261.
40. Aviles-Jimenez F, Vazquez-Jimenez F, Medrano-Guzman R, et al. Stomach microbiota composition varies between patients with non-atrophic gastritis and patients with intestinal type of gastric cancer. Sci Rep 2014; 4: 4202.
41. Yu G, Gail MH, Shi J, et al. Association between upper digestive tract microbiota and cancer-predisposing states in the esophagus and stomach. Cancer Epidemiol Biomarkers Prev 2014; 23: 735–741.
42. Dicksved J, Lindberg M, Rosenquist M, et al. Molecular characterization of the stomach microbiota in patients with gastric cancer and in controls. J Med Microbiol 2009; 58: 509–516.
43. Wang LL, Yu XJ, Zhan SH, et al. Participation of microbiota in the development of gastric cancer. World J Gastroenterol 2014; 20: 4948–4952.
44. Eun CS, Kim BK, Han DS, et al. Differences in gastric mucosal microbiota profiling in patients with chronic gastritis, intestinal metaplasia and gastric cancer using pyrosequencing methods. Helicobacter 2014; 19: 407–416.
45. Brawner KM, Morrow CD and Smith PD. Gastric microbiome and gastric cancer. Cancer J 2014; 20: 211–216.