Personalized medicine: Prediction of disease vulnerability in mood disorders

Neuroscience Letters

Volumn 669, Issue , 2018, Pages 10-13

  Prendes Alvarez, Stefania ^a   Nemeroff, Charles B ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Disease vulnerability; Mood disorders; Personalized medicine; Prediction

Indexed keywords

BIOLOGICAL MARKER;

BIPOLAR DISORDER; DISEASE PREDISPOSITION; ELECTROENCEPHALOGRAM; EPIGENETICS; GENETIC RISK; HUMAN; MAJOR DEPRESSION; NEUROIMAGING; PERSONALIZED MEDICINE; PREDICTION; PRIORITY JOURNAL; PSYCHIATRIST; REVIEW; RISK ASSESSMENT; RISK FACTOR; SYSTEMATIC REVIEW; DIAGNOSTIC IMAGING; ELECTROENCEPHALOGRAPHY; GENETICS; MOOD DISORDER; PROCEDURES; PSYCHOLOGY;

BIPOLAR DISORDER; DEPRESSIVE DISORDER, MAJOR; DISEASE SUSCEPTIBILITY; ELECTROENCEPHALOGRAPHY; EPIGENOMICS; HUMANS; MOOD DISORDERS; NEUROIMAGING; PRECISION MEDICINE;

EID: 85006137629     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2016.09.049     Document Type: Review

References (38)

1. Abdolmaleky, H.M., Cheng, K.-H., Faraone, S.V., Wilcox, M., Glatt, S.J., et al. Hypomethylation of MB-COMT promoter is a major risk factor for schizophrenia and bipolar disorder. Hum. Mol. Genet. 15 (2006), 3132–3145.
2. Belle, D., Doucet, J., Povery, inequality, and discrimination as sources of depression among US women. Psychol. Women Quart. 27 (2003), 101–113.
3. Bradley, R.G., Binder, E.B., Epstein, M.P., Tang, Y., Nair, H.P., et al. Influence of child abuse on adult depression: moderation of the corticotropin–releasing hormone receptor gene. JAMA Psychiatry 65 (2008), 190–200.
4. Caspi, A., Sugden, K., Moffitt, T.E., Taylor, A., Craig, I.W., et al. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 301 (2003), 386–389.
5. Claes, S., Villafuerte, S., Forsgren, T., Slujis, S., Del-Favero, J., et al. The corticotropin-releasing hormone binding protein is associated with major depression in a population from Northern Sweden. Biol. Psychiatry 54 (2003), 867–872.
6. Craddock, N., Jones, I., Genetics of bipolar disorder. J. Med. Genet. 36 (1999), 585–594.
7. Dryman, A., Eaton, W.W., Affective sympyoms associated wit hthe onset of major depression in the community: findings from the US National Institute of Mental Health Epidemiologic Catchment Area Program. Acta Psychiatr. Scand. 84 (1991), 1–5.
8. Fernandes, B.S., Gama, C.S., Cereser, K.M., Yatham, L.N., Fries, G.R., et al. Brain-derived neurotrophic factor as a state-marker of mood episodes in bipolar disorders: a systematic review and meta-regression analysis. J. Psychiatr. Res. 45 (2011), 995–1004.
9. Frodly, T., Moller, H.-J., Meisenzahl, E., Neuroimaging genetics: new perspectives in research on major depression?. Acta Psychiatr. Scand. 118 (2008), 363–372.
10. Gatt, J.M., Nemeroff, C.B., Schofield, P.R., Paul, R.H., Clark, C.R., et al. Early life stress combined with serotonin 3A receptor and brain-derived neurotrophic factor valine 66 to methionine genotypes impacts emotional brain and arousal correlates of risk for depression. Biol. Psychiatry 68 (2010), 818–824.
11. Gatt, J.M., Williams, L.M., Schofield, P.R., Dobson-Stone, C., Paul, R.H., et al. Impact of the HTR3A gene with early life trauma on emotional brain networks and depressed mood. Depress. Anxiety 27 (2010), 752–759.
12. Greicius, M.D., Flores, B.H., Menon, V., Glover, G.H., Solvason, H.B., et al. Resting-state functional connectivity in major depression: abnormally increased contributions from subgenual cingulate cortex and thalamus. Biol. Psychiatry 62 (2007), 429–437.
13. Green, E.K., Grozeva, D., Forty, L., Gordon-Smith, K., Russell, E., et al. Association at SYNE1 in both bipolar disorder and recurrent major depression. Mol. Psychiatry 18 (2012), 614–617.
14. Hoefgen, B., Sculze, T.G., Ohlraun, S., Von Widdern, O., Hofels, S., et al. The power of sample size and homogenous sampling: association between the 5-HTTLPR serotonin transporter polymorphism and major depressive disorder. Biol. Psychiatry 57 (2005), 247–251.
15. Hussain, M.M., Rush, A.J., Wisniewski, S.R., McClintock, S.M., Fava, M., et al. Family history of depression and therapeutic outcome: findings from STAR*D. J. Clin. Psychiatry 70 (2009), 185–195.
16. Kozak, M.J., Cuthbert, B.N., The NIMH research domain criteria initiative: background, issues, and pragmatics. Psychophysiology 53 (2016), 286–297.
17. Laje, G., Perlis, R.H., Rush, A.J., McMahon, F.J., Pharmacogenetics studies in STAR*D: strengths, limitations, and results. Psychiatr. Serv. 60 (2009), 1446–1457.
18. Lee, B.H., Kim, Y.K., The roles of BDNF in the pathophysiology of major depression and in antidepressant treatment. Psychiatry Investig. 7 (2010), 231–235.
19. Lohoff, F.W., Overview of the genetics of major depressive disorder. Curr. Psychiatry Rep. 12 (2010), 539–546.
20. McGowan, P.O., Sasaki, A., D'Alessio, A.C., Dymov, S., Labonte, B., et al. Epigenetic regulation of the glucocorticoid reception in human brain associated with childhood abuse. Nat. Neurosci. 12:34 (2009), 2–348.
21. Mullen, P.E., Martin, J.L., Anderson, J.C., Romans, S.E., Herbison, G.P., The long-term impact of the physical, emotional and sexual abuse of children: a community study. Child Abuse Negl. 20 (1996), 7–21.
22. Musselman, D.L., Evans, D.L., Nemeroff, C.B., The relationship of depression and cardiovascular disease: epidemiology, biology and treatment. JAMA Psychiatry 55 (1998), 580–592.
23. Ozomaro, U., Nemeroff, C.B., Wahlestedt, C., Personalized medicine and psychiatry: dream or reality?. Psychiatr. Times, 2013.
24. Perlis, R.H., Moorjani, P., Fagerness, J., Purcell, S., Trivedi, M.H., et al. Pharmacogenetic analysis of genes implicated in rodent models of antidepressant response: association of TREK1 and treatment resistance in the STAR*D study. Neuropsychopharmacology 33 (2008), 2810–2819.
25. Pompili, M., Venturini, P., Lamis, D.A., Giordana, G., Serafini, G., et al. Suicide in stroke survivors: epidemiology and prevention. Drugs Aging 32 (2015), 21–29.
26. Rao, U., Chen, L., Bidesi, A.S., Shad, M.U., Thomas, M.A., et al. Hippocampal changes associated with early-life adversity and vulnerability to depression. Biol. Psychiatry 67 (2010), 357–364.
27. Reddy, M.S., Depression: the disorder and the burden. Indian J. Psychol. Med. 32 (2010), 1–2.
28. Roy, A., Hodgkinson, C.A., DeLuca, V., Goldman, D., Enoch, M.A., Two HPA axis genes, CRHBP and FKBP5, interact with childhood trauma to increase the risk for suicidal behavior. J. Psychiatr. Res. 46 (2012), 72–79.
29. Saveanu, R.V., Nemeroff, C.B., Etiology of depression: genetic and environmental factors. Psychiatr. Clin. N. Am. 35 (2012), 51–71.
30. Schmaal, L., Veltman, D.J., van Erp, T.G.M., Samann, P.G., Frodl, T., et al. Subcortical brain alterations in major depressive disorder: findings from the ENIGMA major depressive disorder working group. Mol. Psychiatry, 2015, 1–7.
31. Setiawan, E., Wilson, A.A., Mizrahi, R., Rusjan, P.M., Miler, L., et al. Role of translocator protein density, a marker of neuroinflammation, in the brain during major depressive episodes. JAMA Psychiatry 72 (2015), 268–275.
32. Smoller, J.W., Finnt, C.T., Family, twin and adoption studies of bipolar disorder. Am. J. Med. Genet. Part C: Semin. Med. Genet. 123C (2003), 48–58.
33. Steiger, A., Kimura, M., Wake and sleep EEG provide biomarkers for depression. J. Psychiatr. Res. 44 (2010), 242–252.
34. Terracciano, A., Tanaka, T., Sutin, A.R., Sanna, S., Deiana, B., et al. Genome-wide association scan of train depression. Biol. Psychiatry 68 (2010), 811–817.
35. Wichers, M., Myin-Germeys, I., Jacobs, N., Peeters, F., Kenis, G., et al. Genetic risk of depression and stress-induced negative affect in daily life. Br. J. Psychiatry 191 (2007), 218–223.
36. Willour, V.L., Chen, H., Toolan, J., Belmonte, P., Cutler, D.J., et al. Family-based association of FKBP5 in bipolar disorder. Mol. Psychiatry 14 (2009), 261–268.
37. Woon, F.L., Hedges, D.W., Hippocampal and amygdala volumes in children and adults with childhood maltreatment-related posttraumatic stress disorder: a meta-analysis. Hippocampus 18 (2008), 729–736.
38. Zimmermann, P., Bruckl, T., Nocon, A., Phister, H., Binder, E.B., et al. Interaction of FKBP5 gene variants and life events in predicting depression onset: results from a 10-year prospective community study. Am. J. Psychiatry 168 (2011), 1107–1116.