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Volumn 27, Issue 8, 2010, Pages 752-759

Impact of the HTR3A gene with early life trauma on emotional brain networks and depressed mood

Author keywords

Brain Research and Integrative Neuroscience Network (BRAINnet); Brain Resource International Database; Depression; Emotional brain imaging; HTR3A; Stress

Indexed keywords

SEROTONIN 3A RECEPTOR;

EID: 77956841221     PISSN: 10914269     EISSN: 15206394     Source Type: Journal    
DOI: 10.1002/da.20726     Document Type: Article
Times cited : (74)

References (50)
  • 1
    • 67649327144 scopus 로고    scopus 로고
    • Interactions between BDNF Val66Met polymorphism and early life stress predict brain and arousal pathways to syndromal depression and anxiety
    • Gatt JM, Nemeroff CB, Dobson-Stone C. Interactions between BDNF Val66Met polymorphism and early life stress predict brain and arousal pathways to syndromal depression and anxiety. Molecular Psychiatry 2009;14:681-695.
    • (2009) Molecular Psychiatry , vol.14 , pp. 681-695
    • Gatt, J.M.1    Nemeroff, C.B.2    Dobson-Stone, C.3
  • 2
    • 34249774272 scopus 로고    scopus 로고
    • Integrating genomics and neuromarkers for the era of brain-related personalized medicine
    • Gordon E. Integrating genomics and neuromarkers for the era of brain-related personalized medicine. Pers Med 2007;4:201-2152.
    • (2007) Pers Med , vol.4 , pp. 201-2152
    • Gordon, E.1
  • 4
    • 34249790916 scopus 로고    scopus 로고
    • The dynamic organization of the emotional brain: Responsivity, stability and instability
    • Williams LM, Gordon E. The dynamic organization of the emotional brain: Responsivity, stability and instability. The Neuroscientist 2007;13:349-370.
    • (2007) The Neuroscientist , vol.13 , pp. 349-370
    • Williams, L.M.1    Gordon, E.2
  • 5
    • 0032730256 scopus 로고    scopus 로고
    • The impact of early adverse experiences on brain systems involved in the pathophysiology of anxiety and affective disorders
    • Heim C, Nemeroff CB. The impact of early adverse experiences on brain systems involved in the pathophysiology of anxiety and affective disorders. Biol Psychiatry 1999;46:1509-1522.
    • (1999) Biol Psychiatry , vol.46 , pp. 1509-1522
    • Heim, C.1    Nemeroff, C.B.2
  • 6
    • 0031427087 scopus 로고    scopus 로고
    • Childhood adversity and vulnerability to mood and anxiety disorders
    • Young EA, Abelson JL, Curtis GC, Nesse RM. Childhood adversity and vulnerability to mood and anxiety disorders. Depress Anxiety 1997;5:66-72.
    • (1997) Depress Anxiety , vol.5 , pp. 66-72
    • Young, E.A.1    Abelson, J.L.2    Curtis, G.C.3    Nesse, R.M.4
  • 7
    • 0034329673 scopus 로고    scopus 로고
    • Emotion, plasticity, context, and regulation: Perspectives from affective neuroscience
    • Davidson RJ, Jackson DC, Kalin NH. Emotion, plasticity, context, and regulation: Perspectives from affective neuroscience. Psychol Bull 2000;126:890-909.
    • (2000) Psychol Bull , vol.126 , pp. 890-909
    • Davidson, R.J.1    Jackson, D.C.2    Kalin, N.H.3
  • 8
    • 33847364801 scopus 로고    scopus 로고
    • Defining the neural circuitry of depression: Toward a new nosology with therapeutic implications
    • Mayberg HS. Defining the neural circuitry of depression: Toward a new nosology with therapeutic implications. Biol Psychiatry 2007;61:729-730.
    • (2007) Biol Psychiatry , vol.61 , pp. 729-730
    • Mayberg, H.S.1
  • 9
    • 0037624040 scopus 로고    scopus 로고
    • Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene
    • Caspi A, Sugden K, Moffitt TE, et al. Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene. Science 2003;301:386-389.
    • (2003) Science , vol.301 , pp. 386-389
    • Caspi, A.1    Sugden, K.2    Moffitt, T.E.3
  • 10
    • 0024473254 scopus 로고
    • Identification and characterisation of 5-HT3 recognition sites in human brain tissue
    • Barnes JM, Barnes NM, Costall B, Ironside JW, Naylor RJ. Identification and characterisation of 5-HT3 recognition sites in human brain tissue. J Neurochem 1989;53:1787-1793.
    • (1989) J Neurochem , vol.53 , pp. 1787-1793
    • Barnes, J.M.1    Barnes, N.M.2    Costall, B.3    Ironside, J.W.4    Naylor, R.J.5
  • 11
    • 0027787995 scopus 로고
    • Distribution and characterisation of the [3H]granisetron-labelled 5-HT3 receptor in the human forebrain
    • Bufton KE, Steward LJ, Barber PC, Barnes NM. Distribution and characterisation of the [3H]granisetron-labelled 5-HT3 receptor in the human forebrain. Neuropharmacology 1993;32:1325-1331.
    • (1993) Neuropharmacology , vol.32 , pp. 1325-1331
    • Bufton, K.E.1    Steward, L.J.2    Barber, P.C.3    Barnes, N.M.4
  • 12
    • 0030299837 scopus 로고    scopus 로고
    • Autoradiographic distribution of [3H]-(S)-zacopride-labelled 5-HT3 receptors in human brain
    • Parker RM, Barnes JM, Ge J, Barber PC, Barnes NM. Autoradiographic distribution of [3H]-(S)-zacopride-labelled 5-HT3 receptors in human brain. J Neurol Sci 1996;144:119-127.
    • (1996) J Neurol Sci , vol.144 , pp. 119-127
    • Parker, R.M.1    Barnes, J.M.2    Ge, J.3    Barber, P.C.4    Barnes, N.M.5
  • 13
    • 0027409041 scopus 로고
    • Neurobiology Nervous system distribution of the serotonin 5-HT3 receptor mRNA
    • Tecott LH, Maricq AV, Julius D. Neurobiology Nervous system distribution of the serotonin 5-HT3 receptor mRNA. PNAS USA 1993;90:1430-1434.
    • (1993) PNAS USA , vol.90 , pp. 1430-1434
    • Tecott, L.H.1    Maricq, A.V.2    Julius, D.3
  • 14
    • 0025997336 scopus 로고
    • Primary structure and functional expression of the 5HT3 receptor, a serotonin gated ion channel
    • Maricq AV, Peterson AS, Brake AJ, Myers RM, Julius D. Primary structure and functional expression of the 5HT3 receptor, a serotonin gated ion channel. Science 1991;24:432-437.
    • (1991) Science , vol.24 , pp. 432-437
    • Maricq, A.V.1    Peterson, A.S.2    Brake, A.J.3    Myers, R.M.4    Julius, D.5
  • 15
    • 0026595848 scopus 로고
    • 5-hydroxytryptamine is a fast excitatory transmitter at 5-HT3 receptors in rat amygdala
    • Sugita S, Shen KZ, North RA. 5-hydroxytryptamine is a fast excitatory transmitter at 5-HT3 receptors in rat amygdala. Neuron 1992;8:199-203.
    • (1992) Neuron , vol.8 , pp. 199-203
    • Sugita, S.1    Shen, K.Z.2    North, R.A.3
  • 16
    • 2642511290 scopus 로고    scopus 로고
    • Changes in anxiety-related behaviors and hypothalamic-pituitary- adrenal activity in mice lacking the 5-HT-3A receptor
    • Bhatnagar S, Sun LM, Raber J, Maren S, Julius D, Dallman MF. Changes in anxiety-related behaviors and hypothalamic-pituitary- adrenal activity in mice lacking the 5-HT-3A receptor. Physiol Behav 2004;81:545-555.
    • (2004) Physiol Behav , vol.81 , pp. 545-555
    • Bhatnagar, S.1    Sun, L.M.2    Raber, J.3    Maren, S.4    Julius, D.5    Dallman, M.F.6
  • 17
    • 0142121567 scopus 로고    scopus 로고
    • Improvements in hippocampal-dependent learning and decremental attention in 5-HT3 receptor overexpressing mice
    • Harrell AV, Allan AM. Improvements in hippocampal-dependent learning and decremental attention in 5-HT3 receptor overexpressing mice. Learn Mem 2003;10:410-419.
    • (2003) Learn Mem , vol.10 , pp. 410-419
    • Harrell, A.V.1    Allan, A.M.2
  • 20
    • 0036018482 scopus 로고    scopus 로고
    • Evaluating the state dependency of the temperament and character inventory dimensions in patients with major depression: A methodological contribution
    • Hirano S, Sato T, Narita T, et al. Evaluating the state dependency of the temperament and character inventory dimensions in patients with major depression: A methodological contribution. J Affect Disord 2002;69:31-38.
    • (2002) J Affect Disord , vol.69 , pp. 31-38
    • Hirano, S.1    Sato, T.2    Narita, T.3
  • 21
    • 33748526872 scopus 로고    scopus 로고
    • Temperament, character and symptoms of anxiety and depression in the general population
    • Pekka J, Erkki I. Temperament, character and symptoms of anxiety and depression in the general population. Eur Psychiatry 2006;21:389-395.
    • (2006) Eur Psychiatry , vol.21 , pp. 389-395
    • Pekka, J.1    Erkki, I.2
  • 22
    • 10744223528 scopus 로고    scopus 로고
    • A polymorphism in the serotonin receptor 3A (HTR3A) gene and its association with harm avoidance in women
    • Melke J, Westberg L, Nilsson S, et al. A polymorphism in the serotonin receptor 3A (HTR3A) gene and its association with harm avoidance in women. Arch Gen Psychiatry 2003;60:1017-1023.
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 1017-1023
    • Melke, J.1    Westberg, L.2    Nilsson, S.3
  • 23
    • 22044431993 scopus 로고    scopus 로고
    • A variant C178T in the regulatory region of the serotonin receptor gene HTR3A modulates neural activation in the human amygdala
    • Iidaka T, Ozaki N, Matsumoto A, et al. A variant C178T in the regulatory region of the serotonin receptor gene HTR3A modulates neural activation in the human amygdala. J Neurosci 2005;25:6460-6466.
    • (2005) J Neurosci , vol.25 , pp. 6460-6466
    • Iidaka, T.1    Ozaki, N.2    Matsumoto, A.3
  • 24
    • 33745698343 scopus 로고    scopus 로고
    • Distinguishable haplotype blocks in the HTR3A and HTR3B region in the Japanese reveal evidence of association of HTR3B with female major depression
    • Yamada K, Hattori E, Iwayama Y, et al. Distinguishable haplotype blocks in the HTR3A and HTR3B region in the Japanese reveal evidence of association of HTR3B with female major depression. Biol Psychiatry 2006;60:192-201.
    • (2006) Biol Psychiatry , vol.60 , pp. 192-201
    • Yamada, K.1    Hattori, E.2    Iwayama, Y.3
  • 27
    • 0025923219 scopus 로고
    • The Fagerström test for nicotine dependence: A revision of the Fagerström Tolerance Questionnaire
    • Heatherton TF, Kozlowski LT, Frecker RC, Fagerström KO. The Fagerström test for nicotine dependence: A revision of the Fagerström Tolerance Questionnaire. Brit J Addict 1991;86: 1119-1127.
    • (1991) Brit J Addict , vol.86 , pp. 1119-1127
    • Heatherton, T.F.1    Kozlowski, L.T.2    Frecker, R.C.3    Fagerström, K.O.4
  • 29
    • 33644753148 scopus 로고    scopus 로고
    • Psychiatric endophenotypes and the development of valid animal models
    • Gould TD, Gottesman II. Psychiatric endophenotypes and the development of valid animal models. Genes Brain Behav 2006; 5:113-119.
    • (2006) Genes Brain Behav , vol.5 , pp. 113-119
    • Gould, T.D.1    Gottesman, I.I.2
  • 31
    • 0031841630 scopus 로고    scopus 로고
    • Psychometric properties of the 42-item and 21-item versions of the Depression Anxiety Stress Scales in clinical groups and a community sample
    • Antony MM, Bieling PJ, Cox BJ, Enns MW, Swinson RP. Psychometric properties of the 42-item and 21-item versions of the Depression Anxiety Stress Scales in clinical groups and a community sample. Psychol Assess 1998;10:176-181.
    • (1998) Psychol Assess , vol.10 , pp. 176-181
    • Antony, M.M.1    Bieling, P.J.2    Cox, B.J.3    Enns, M.W.4    Swinson, R.P.5
  • 32
    • 0038142370 scopus 로고    scopus 로고
    • The Depression Anxiety Stress Scales (DASS): Normative data and latent structure in a large nonclinical sample
    • Crawford JR, Henry JD. The Depression Anxiety Stress Scales (DASS): Normative data and latent structure in a large nonclinical sample. Brit J Clin Psychol 2003;42:111-131.
    • (2003) Brit J Clin Psychol , vol.42 , pp. 111-131
    • Crawford, J.R.1    Henry, J.D.2
  • 33
    • 21044440731 scopus 로고    scopus 로고
    • The short-form version of the Depression Anxiety Stress Scales (DASS-21): Construct validity and normative data in a large non-clinical sample
    • Henry JD, Crawford JR. The short-form version of the Depression Anxiety Stress Scales (DASS-21): Construct validity and normative data in a large non-clinical sample. Brit J Clin Psychol 2005;44:227-239.
    • (2005) Brit J Clin Psychol , vol.44 , pp. 227-239
    • Henry, J.D.1    Crawford, J.R.2
  • 35
    • 0024245652 scopus 로고    scopus 로고
    • An inventory for measuring clinical anxiety: Psychometric properties
    • Beck AT, Epstein N, Brown G, Steer RA. An inventory for measuring clinical anxiety: Psychometric properties. J Consult Clin Psychol 1998;56:893-897.
    • (1998) J Consult Clin Psychol , vol.56 , pp. 893-897
    • Beck, A.T.1    Epstein, N.2    Brown, G.3    Steer, R.A.4
  • 36
    • 0028954540 scopus 로고
    • The measurement of psychological maltreatment: Early data on the Child Abuse and Trauma Scale
    • Sanders B, Becker-Lausen E. The measurement of psychological maltreatment: Early data on the Child Abuse and Trauma Scale. Child Abuse Negl 1995;19:315-323.
    • (1995) Child Abuse Negl , vol.19 , pp. 315-323
    • Sanders, B.1    Becker-Lausen, E.2
  • 37
    • 0033933649 scopus 로고    scopus 로고
    • Voxel-based morphometry-The methods
    • Ashburner J, Friston KJ. Voxel-based morphometry-The methods. Neuroimage 2000;11:805-821.
    • (2000) Neuroimage , vol.11 , pp. 805-821
    • Ashburner, J.1    Friston, K.J.2
  • 40
    • 0036322886 scopus 로고    scopus 로고
    • Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single subject brain
    • Tzourio-Mazoyer M, Landeau B, Papathanassiou D, et al. Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single subject brain. Neuroimage 2002;15:273-289.
    • (2002) Neuroimage , vol.15 , pp. 273-289
    • Tzourio-Mazoyer, M.1    Landeau, B.2    Papathanassiou, D.3
  • 44
    • 0033756168 scopus 로고    scopus 로고
    • A volumetric study of hippocampus and amygdala in depressed patients with subjective memory problems
    • Von Gunten A, Fox, NC, Cipolotti L, Ron MA. A volumetric study of hippocampus and amygdala in depressed patients with subjective memory problems. J Neuropsychiatry Clin Neurosci 2000;12:493-498.
    • (2000) J Neuropsychiatry Clin Neurosci , vol.12 , pp. 493-498
    • Von Gunten, A.1    Fox, N.C.2    Cipolotti, L.3    Ron, M.A.4
  • 45
    • 0036895697 scopus 로고    scopus 로고
    • Childhood trauma associated with smaller hippocampal volume in women with major depression
    • Vythilingam M, Heim C, Newport J, et al. Childhood trauma associated with smaller hippocampal volume in women with major depression. Am J Psychiatry 2002;159:2072-2080.
    • (2002) Am J Psychiatry , vol.159 , pp. 2072-2080
    • Vythilingam, M.1    Heim, C.2    Newport, J.3
  • 46
    • 0033232499 scopus 로고    scopus 로고
    • Neural plasticity to stress and antidepressant Treatment
    • Duman RS, Malberg J, Thome J. Neural plasticity to stress and antidepressant Treatment. Biol Psychiatry 1999;46:1181-1191.
    • (1999) Biol Psychiatry , vol.46 , pp. 1181-1191
    • Duman, R.S.1    Malberg, J.2    Thome, J.3
  • 47
    • 18344396274 scopus 로고    scopus 로고
    • Strategy for investigating interactions between measured genes and measured environments
    • Moffitt TE, Caspi A, Rutter M. Strategy for investigating interactions between measured genes and measured environments. Arch Gen Psychiatry 2005;62:473-481.
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 473-481
    • Moffitt, T.E.1    Caspi, A.2    Rutter, M.3
  • 48
    • 34248221079 scopus 로고    scopus 로고
    • A genotype-endophenotype- phenotype path model of depressed mood: Integrating cognitive and emotional markers
    • Gatt JM, Clark CR, Kemp AH, et al. A genotype-endophenotype- phenotype path model of depressed mood: Integrating cognitive and emotional markers. J Integr Neurosci 2007;6: 75-104.
    • (2007) J Integr Neurosci , vol.6 , pp. 75-104
    • Gatt, J.M.1    Clark, C.R.2    Kemp, A.H.3
  • 49
    • 51049099157 scopus 로고    scopus 로고
    • Association between BDNF Val66Met polymorphism and trait depression is mediated via resting EEG alpha band activity
    • Gatt JM, Kuan S, Dobson-Stone C, et al. Association between BDNF Val66Met polymorphism and trait depression is mediated via resting EEG alpha band activity. Biol Psychol 2008;79:275-284.
    • (2008) Biol Psychol , vol.79 , pp. 275-284
    • Gatt, J.M.1    Kuan, S.2    Dobson-Stone, C.3
  • 50
    • 77956850813 scopus 로고    scopus 로고
    • Early life stress combined with HTR3A and BDNF Val66Met genotypes impacts emotional brain and arousal correlates of risk for depression
    • in press
    • Gatt JM, Nemeroff CB, Schofield PR, et al. Early life stress combined with HTR3A and BDNF Val66Met genotypes impacts emotional brain and arousal correlates of risk for depression. Biol Psychiatry 2010, in press.
    • Biol Psychiatry 2010
    • Gatt, J.M.1    Nemeroff, C.B.2    Schofield, P.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.