Single-Cell Analysis Reveals a Close Relationship between Differentiating Dopamine and Subthalamic Nucleus Neuronal Lineages

Cell Stem Cell

Volumn 20, Issue 1, 2017, Pages 29-40

  Kee, Nigel ^a,b   Volakakis, Nikolaos ^a   Kirkeby, Agnete ^c   Dahl, Lina ^a   Storvall, Helena ^a   Nolbrant, Sara ^c   Lahti, Laura ^a   Björklund, Åsa K ^d   Gillberg, Linda ^a   Joodmardi, Eliza ^a   Sandberg, Rickard ^a,b   Parmar, Malin ^c   Perlmann, Thomas ^a,b  

^a LUDWIG INSTITUTE FOR CANCER RESEARCH   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c LUND UNIVERSITY   (Sweden)

^d UPPSALA UNIVERSITY   (Sweden)

Author keywords

development; dopamine; embryogenesis; graph clustering; hypothalamus; neurogenesis; Parkinson's disease; single cell RNA seq; stem cell; subthalamic nucleus

Indexed keywords

BIOLOGICAL MARKER; CHEMOKINE RECEPTOR CXCR4; DOPAMINE TRANSPORTER; DOUBLECORTIN; EPHRIN RECEPTOR A3; HEPATOCYTE NUCLEAR FACTOR 3ALPHA; HEPATOCYTE NUCLEAR FACTOR 3BETA; NEUROGENIC DIFFERENTIATION FACTOR; NEUROGENIN 2; NUCLEAR RECEPTOR RELATED FACTOR 1; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 2; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR LMX1A; TRANSCRIPTION FACTOR MASH1; TRANSCRIPTION FACTOR MSX1; TRANSCRIPTION FACTOR MSX2; TRANSCRIPTION FACTOR NKX6.1; TRANSCRIPTION FACTOR OTX2; TRANSCRIPTION FACTOR PITX2; TRANSCRIPTION FACTOR PITX3; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG; VESICULAR MONOAMINE TRANSPORTER 2; WNT1 PROTEIN; WNT8B PROTEIN; LIM HOMEODOMAIN PROTEIN; LMX1A PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CELL ENGINEERING; CELL LINEAGE; CELL PROLIFERATION; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; EMBRYO; FEMALE; HUMAN; HUMAN CELL; HUMAN EMBRYONIC STEM CELL; HUMAN TISSUE; MESENCEPHALON; MOUSE; NERVE CELL DIFFERENTIATION; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA SEQUENCE; SINGLE CELL ANALYSIS; SUBTHALAMIC NUCLEUS; CELL DIFFERENTIATION; CYTOLOGY; EMBRYONIC STEM CELL; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORK; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; MORPHOGENESIS; NERVOUS SYSTEM DEVELOPMENT; PROCEDURES; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION;

BIOMARKERS; BODY PATTERNING; CELL DIFFERENTIATION; CELL LINEAGE; DOPAMINERGIC NEURONS; EMBRYONIC STEM CELLS; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORKS; HUMANS; IMMUNOHISTOCHEMISTRY; LIM-HOMEODOMAIN PROTEINS; NEUROGENESIS; SEQUENCE ANALYSIS, RNA; SIGNAL TRANSDUCTION; SINGLE-CELL ANALYSIS; SUBTHALAMIC NUCLEUS; TRANSCRIPTION FACTORS;

EID: 85006080817     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2016.10.003     Document Type: Article

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