Ophiobolin a induces autophagy and activates the mitochondrial pathway of apoptosis in human melanoma cells

PLoS ONE

Volumn 11, Issue 12, 2016, Pages

  Rodolfo, Carlo ^a   Rocco, Mariapina ^b   Cattaneo, Lucia ^a   Tartaglia, Maria ^b   Sassi, Mauro ^c   Aducci, Patrizia ^a   Scaloni, Andrea ^c   Camoni, Lorenzo ^a   Marra, Mauro ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b UNIVERSITY OF SANNIO   (Italy)

^c CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 9; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN A8; MEMBRANE PROTEIN; MYCOTOXIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; OPHIOBOLIN A; PEPTIDYLPROLYL ISOMERASE; PEPTIDYLPROLYL ISOMERASE A; PREFOLDIN; REACTIVE OXYGEN METABOLITE; TAPASIN; TRANSLATIONALLY CONTROLLED TUMOR PROTEIN; TUMOR PROTEIN; UNCLASSIFIED DRUG; VOLTAGE DEPENDENT ANION CHANNEL 1; SESTERTERPENE;

A375 CELL LINE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CELL HOMEOSTASIS; CELL MEMBRANE DEPOLARIZATION; CELL STRUCTURE; CELL VIABILITY; CELLULAR, SUBCELLULAR AND MOLECULAR BIOLOGICAL PHENOMENA AND FUNCTIONS; CHL 1 CELL LINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; HOMEOSTASIS; HUMAN; HUMAN CELL; INCIDENCE; MELANOMA CELL LINE; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL NETWORK FRAGMENTATION; NUCLEAR REPROGRAMMING; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEOMICS; WESTERN BLOTTING; ASCOMYCETES; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; MELANOMA; METABOLISM; MITOCHONDRION; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; ASCOMYCOTA; AUTOPHAGY; CELL LINE, TUMOR; CELL SURVIVAL; HUMANS; MELANOMA; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; REACTIVE OXYGEN SPECIES; SESTERTERPENES; SIGNAL TRANSDUCTION;

EID: 85006062795     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0167672     Document Type: Article

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