-
1
-
-
78649516124
-
Functions of T cells in asthma: more than just TH2 cells
-
Lloyd CM, Hessel EM. Functions of T cells in asthma: more than just TH2 cells. Nat Rev Immunol 2010;10:838–848.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 838-848
-
-
Lloyd, C.M.1
Hessel, E.M.2
-
2
-
-
84860655039
-
Innate and adaptive immune responses in asthma
-
Holgate ST. Innate and adaptive immune responses in asthma. Nat Med 2012;18:673–683.
-
(2012)
Nat Med
, vol.18
, pp. 673-683
-
-
Holgate, S.T.1
-
3
-
-
84897146503
-
Innate lymphoid cells and asthma
-
Yu S, Kim HY, Chang Y-J, DeKruyff RH, Umetsu DT. Innate lymphoid cells and asthma. J Allergy Clin Immunol 2014;133:943–950.
-
(2014)
J Allergy Clin Immunol
, vol.133
, pp. 943-950
-
-
Yu, S.1
Kim, H.Y.2
Chang, Y.-J.3
DeKruyff, R.H.4
Umetsu, D.T.5
-
4
-
-
84896955392
-
Asthma: the importance of dysregulated barrier immunity
-
Lambrecht BN, Hammad H. Asthma: the importance of dysregulated barrier immunity. Eur J Immunol 2013;43:3125–3137.
-
(2013)
Eur J Immunol
, vol.43
, pp. 3125-3137
-
-
Lambrecht, B.N.1
Hammad, H.2
-
5
-
-
84860691114
-
The airway epithelium in asthma
-
Lambrecht BN, Hammad H. The airway epithelium in asthma. Nat Med 2012;18:684–692.
-
(2012)
Nat Med
, vol.18
, pp. 684-692
-
-
Lambrecht, B.N.1
Hammad, H.2
-
6
-
-
80051930931
-
Orchestrating house dust mite-associated allergy in the lung
-
Gregory LG, Lloyd CM. Orchestrating house dust mite-associated allergy in the lung. Trends Immunol 2011;32:402–411.
-
(2011)
Trends Immunol
, vol.32
, pp. 402-411
-
-
Gregory, L.G.1
Lloyd, C.M.2
-
7
-
-
84856641109
-
NF-κB, the first quarter-century: remarkable progress and outstanding questions
-
Hayden MS, Ghosh S. NF-κB, the first quarter-century: remarkable progress and outstanding questions. Genes Dev 2012;26:203–234.
-
(2012)
Genes Dev
, vol.26
, pp. 203-234
-
-
Hayden, M.S.1
Ghosh, S.2
-
9
-
-
54949147176
-
New regulators of NF-κB in inflammation
-
Ghosh S, Hayden MS. New regulators of NF-κB in inflammation. Nat Rev Immunol 2008;8:837–848.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 837-848
-
-
Ghosh, S.1
Hayden, M.S.2
-
10
-
-
14844344042
-
The nuclear IκB protein IκBNS selectively inhibits lipopolysaccharide-induced IL-6 production in macrophages of the colonic lamina propria
-
Hirotani T, Lee PY, Kuwata H, Yamamoto M, Matsumoto M, Kawase I et al. The nuclear IκB protein IκBNS selectively inhibits lipopolysaccharide-induced IL-6 production in macrophages of the colonic lamina propria. J Immunol 2005;174:3650–3657.
-
(2005)
J Immunol
, vol.174
, pp. 3650-3657
-
-
Hirotani, T.1
Lee, P.Y.2
Kuwata, H.3
Yamamoto, M.4
Matsumoto, M.5
Kawase, I.6
-
11
-
-
30444456370
-
IκBNS inhibits induction of a subset of Toll-like receptor-dependent genes and limits inflammation
-
Kuwata H, Matsumoto M, Atarashi K, Morishita H, Hirotani T, Koga R et al. IκBNS inhibits induction of a subset of Toll-like receptor-dependent genes and limits inflammation. Immunity 2006;24:41–51.
-
(2006)
Immunity
, vol.24
, pp. 41-51
-
-
Kuwata, H.1
Matsumoto, M.2
Atarashi, K.3
Morishita, H.4
Hirotani, T.5
Koga, R.6
-
12
-
-
34548617181
-
Functional role for IκBNS in T cell cytokine regulation as revealed by targeted gene disruption
-
Touma M, Antonini V, Kumar M, Osborn SL, Bobenchik AM, Keskin DB et al. Functional role for IκBNS in T cell cytokine regulation as revealed by targeted gene disruption. J Immunol 2007;179:1681–1692.
-
(2007)
J Immunol
, vol.179
, pp. 1681-1692
-
-
Touma, M.1
Antonini, V.2
Kumar, M.3
Osborn, S.L.4
Bobenchik, A.M.5
Keskin, D.B.6
-
13
-
-
84870928198
-
IκBNS protein mediates regulatory T cell development via induction of the Foxp3 transcription factor
-
Schuster M, Glauben R, Plaza-Sirvent C, Schreiber L, Annemann M, Floess S et al. IκBNS protein mediates regulatory T cell development via induction of the Foxp3 transcription factor. Immunity 2012;37:998–1008.
-
(2012)
Immunity
, vol.37
, pp. 998-1008
-
-
Schuster, M.1
Glauben, R.2
Plaza-Sirvent, C.3
Schreiber, L.4
Annemann, M.5
Floess, S.6
-
14
-
-
84908587619
-
The nuclear IκB family protein IκBNS influences the susceptibility to experimental autoimmune encephalomyelitis in a murine model
-
Kobayashi S, Hara A, Isagawa T, Manabe I, Takeda K, MaruYama T. The nuclear IκB family protein IκBNS influences the susceptibility to experimental autoimmune encephalomyelitis in a murine model. PLoS One 2014;9:e110838.
-
(2014)
PLoS One
, vol.9
-
-
Kobayashi, S.1
Hara, A.2
Isagawa, T.3
Manabe, I.4
Takeda, K.5
MaruYama, T.6
-
15
-
-
84924565883
-
IκBNS regulates murine Th17 differentiation during gut inflammation and infection
-
Annemann M, Wang Z, Plaza-Sirvent C, Glauben R, Schuster M, Ewald Sander F et al. IκBNS regulates murine Th17 differentiation during gut inflammation and infection. J Immunol 2015;194:2888–2898.
-
(2015)
J Immunol
, vol.194
, pp. 2888-2898
-
-
Annemann, M.1
Wang, Z.2
Plaza-Sirvent, C.3
Glauben, R.4
Schuster, M.5
Ewald Sander, F.6
-
16
-
-
84947432484
-
The intestinal microbiota contributes to the ability of helminths to modulate allergic inflammation
-
Zaiss MM, Rapin A, Lebon L, Dubey LK, Mosconi I, Sarter K et al. The intestinal microbiota contributes to the ability of helminths to modulate allergic inflammation. Immunity 2015;43:998–1010.
-
(2015)
Immunity
, vol.43
, pp. 998-1010
-
-
Zaiss, M.M.1
Rapin, A.2
Lebon, L.3
Dubey, L.K.4
Mosconi, I.5
Sarter, K.6
-
18
-
-
84894024566
-
Th2-type inflammation instructs inflammatory dendritic cells to induce airway hyperreactivity
-
Iwata A, Kawashima S, Kobayashi M, Okubo A, Kawashima H, Suto A et al. Th2-type inflammation instructs inflammatory dendritic cells to induce airway hyperreactivity. Int Immunol 2014;26:103–114.
-
(2014)
Int Immunol
, vol.26
, pp. 103-114
-
-
Iwata, A.1
Kawashima, S.2
Kobayashi, M.3
Okubo, A.4
Kawashima, H.5
Suto, A.6
-
19
-
-
84941102754
-
Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells
-
Schuijs MJ, Willart MA, Vergote K, Gras D, Deswarte K, Ege MJ et al. Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells. Science 2015;349:1106–1110.
-
(2015)
Science
, vol.349
, pp. 1106-1110
-
-
Schuijs, M.J.1
Willart, M.A.2
Vergote, K.3
Gras, D.4
Deswarte, K.5
Ege, M.J.6
-
20
-
-
57349084248
-
IL-23 and Th17 cells enhance Th2-cell-mediated eosinophilic airway inflammation in mice
-
Wakashin H, Hirose K, Maezawa Y, Kagami S, Suto A, Watanabe N et al. IL-23 and Th17 cells enhance Th2-cell-mediated eosinophilic airway inflammation in mice. Am J Respir Crit Care Med 2008;178:1023–1032.
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 1023-1032
-
-
Wakashin, H.1
Hirose, K.2
Maezawa, Y.3
Kagami, S.4
Suto, A.5
Watanabe, N.6
-
21
-
-
84900529199
-
Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq
-
Treutlein B, Brownfield DG, Wu AR, Neff NF, Mantalas GL, Espinoza FH et al. Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq. Nature 2014;509:371–375.
-
(2014)
Nature
, vol.509
, pp. 371-375
-
-
Treutlein, B.1
Brownfield, D.G.2
Wu, A.R.3
Neff, N.F.4
Mantalas, G.L.5
Espinoza, F.H.6
-
22
-
-
84872683119
-
Efficient and rapid isolation and purification of mouse alveolar type II epithelial cells
-
Messier EM, Mason RJ, Kosmider B. Efficient and rapid isolation and purification of mouse alveolar type II epithelial cells. Exp Lung Res 2012;38:363–373.
-
(2012)
Exp Lung Res
, vol.38
, pp. 363-373
-
-
Messier, E.M.1
Mason, R.J.2
Kosmider, B.3
-
23
-
-
0036891878
-
Growth and differentiation of mouse tracheal epithelial cells: selection of a proliferative population
-
You Y, Richer EJ, Huang T, Brody SL. Growth and differentiation of mouse tracheal epithelial cells: selection of a proliferative population. Am J Physiol Lung Cell Mol Physiol 2002;283:L1315–L1321.
-
(2002)
Am J Physiol Lung Cell Mol Physiol
, vol.283
, pp. L1315-L1321
-
-
You, Y.1
Richer, E.J.2
Huang, T.3
Brody, S.L.4
-
24
-
-
84906556596
-
Sox5 and c-Maf cooperatively induce Th17 cell differentiation via RORγt induction as downstream targets of Stat3
-
Tanaka S, Suto A, Iwamoto T, Kashiwakuma D, Kagami S, Suzuki K et al. Sox5 and c-Maf cooperatively induce Th17 cell differentiation via RORγt induction as downstream targets of Stat3. J Exp Med 2014;211:1857–1874.
-
(2014)
J Exp Med
, vol.211
, pp. 1857-1874
-
-
Tanaka, S.1
Suto, A.2
Iwamoto, T.3
Kashiwakuma, D.4
Kagami, S.5
Suzuki, K.6
-
25
-
-
77950554986
-
c-Maf activates the promoter and enhancer of the IL-21 gene, and TGF-β inhibits c-Maf-induced IL-21 production in CD4 + T cells
-
Hiramatsu Y, Suto A, Kashiwakuma D, Kanari H, Kagami S, Ikeda K et al. c-Maf activates the promoter and enhancer of the IL-21 gene, and TGF-β inhibits c-Maf-induced IL-21 production in CD4 + T cells. J Leukoc Biol 2010;87:703–712.
-
(2010)
J Leukoc Biol
, vol.87
, pp. 703-712
-
-
Hiramatsu, Y.1
Suto, A.2
Kashiwakuma, D.3
Kanari, H.4
Kagami, S.5
Ikeda, K.6
-
26
-
-
77954239363
-
Regulation of airway MUC5AC expression by IL-1beta and IL-17A; the NF-κB paradigm
-
Fujisawa T, Velichko S, Thai P, Hung L-Y, Huang F, Wu R. Regulation of airway MUC5AC expression by IL-1beta and IL-17A; the NF-κB paradigm. J Immunol 2009;183:6236–6243.
-
(2009)
J Immunol
, vol.183
, pp. 6236-6243
-
-
Fujisawa, T.1
Velichko, S.2
Thai, P.3
Hung, L.-Y.4
Huang, F.5
Wu, R.6
-
27
-
-
84900555408
-
IL-1β induction of MUC5AC gene expression is mediated by CREB and NF-κB and repressed by dexamethasone
-
Chen Y, Garvin LM, Nickola TJ, Watson AM, Colberg-Poley AM, Rose MC. IL-1β induction of MUC5AC gene expression is mediated by CREB and NF-κB and repressed by dexamethasone. Am J Physiol Lung Cell Mol Physiol 2014;306:L797–L807.
-
(2014)
Am J Physiol Lung Cell Mol Physiol
, vol.306
, pp. L797-L807
-
-
Chen, Y.1
Garvin, L.M.2
Nickola, T.J.3
Watson, A.M.4
Colberg-Poley, A.M.5
Rose, M.C.6
-
28
-
-
26944443968
-
Distinct roles of IκB proteins in regulating constitutive NF-κB activity
-
Tergaonkar V, Correa RG, Ikawa M, Verma IM. Distinct roles of IκB proteins in regulating constitutive NF-κB activity. Nat Cell Biol 2005;7:921–923.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 921-923
-
-
Tergaonkar, V.1
Correa, R.G.2
Ikawa, M.3
Verma, I.M.4
-
29
-
-
84958088068
-
Role of Bcl-3 in the development of follicular helper T cells and in the pathogenesis of rheumatoid arthritis
-
Meguro K, Suzuki K, Hosokawa J, Sanayama Y, Tanaka S, Furuta S et al. Role of Bcl-3 in the development of follicular helper T cells and in the pathogenesis of rheumatoid arthritis. Arthritis Rheumatol 2015;67:2651–2660.
-
(2015)
Arthritis Rheumatol
, vol.67
, pp. 2651-2660
-
-
Meguro, K.1
Suzuki, K.2
Hosokawa, J.3
Sanayama, Y.4
Tanaka, S.5
Furuta, S.6
-
30
-
-
0036344597
-
Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma
-
Kuperman DA, Huang X, Koth LL, Chang GH, Dolganov GM, Zhu Z et al. Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma. Nat Med 2002;8:885–889.
-
(2002)
Nat Med
, vol.8
, pp. 885-889
-
-
Kuperman, D.A.1
Huang, X.2
Koth, L.L.3
Chang, G.H.4
Dolganov, G.M.5
Zhu, Z.6
-
32
-
-
84923361939
-
The polymeric mucin Muc5ac is required for allergic airway hyperreactivity
-
Evans CM, Raclawska DS, Ttofali F, Liptzin DR, Fletcher AA, Harper DN et al. The polymeric mucin Muc5ac is required for allergic airway hyperreactivity. Nat Commun 2015;6:6281.
-
(2015)
Nat Commun
, vol.6
, pp. 6281
-
-
Evans, C.M.1
Raclawska, D.S.2
Ttofali, F.3
Liptzin, D.R.4
Fletcher, A.A.5
Harper, D.N.6
-
33
-
-
78649735324
-
Airway mucus function and dysfunction
-
Fahy JV, Dickey BF. Airway mucus function and dysfunction. N Engl J Med 2010;363:2233–2247.
-
(2010)
N Engl J Med
, vol.363
, pp. 2233-2247
-
-
Fahy, J.V.1
Dickey, B.F.2
-
34
-
-
34147151188
-
SPDEF regulates goblet cell hyperplasia in the airway epithelium
-
Park KS, Korfhagen TR, Bruno MD, Kitzmiller JA, Wan H, Wert SE et al. SPDEF regulates goblet cell hyperplasia in the airway epithelium. J Clin Invest 2007;117:978–988.
-
(2007)
J Clin Invest
, vol.117
, pp. 978-988
-
-
Park, K.S.1
Korfhagen, T.R.2
Bruno, M.D.3
Kitzmiller, J.A.4
Wan, H.5
Wert, S.E.6
-
35
-
-
84938555475
-
Three cheers for the goblet cell: maintaining homeostasis in mucosal epithelia
-
McCauley HA, Guasch G. Three cheers for the goblet cell: maintaining homeostasis in mucosal epithelia. Trends Mol Med 2015;21:492–503.
-
(2015)
Trends Mol Med
, vol.21
, pp. 492-503
-
-
McCauley, H.A.1
Guasch, G.2
-
36
-
-
84902352161
-
The cell biology of asthma
-
Erle DJ, Sheppard D. The cell biology of asthma. J Cell Biol 2014;205:621–631.
-
(2014)
J Cell Biol
, vol.205
, pp. 621-631
-
-
Erle, D.J.1
Sheppard, D.2
-
37
-
-
18344393786
-
Peptide-induced negative selection of thymocytes activates transcription of an NF-κB inhibitor
-
Fiorini E, Schmitz I, Marissen WE, Osborn SL, Touma M, Sasada T et al. Peptide-induced negative selection of thymocytes activates transcription of an NF-κB inhibitor. Mol Cell 2002;9:637–648.
-
(2002)
Mol Cell
, vol.9
, pp. 637-648
-
-
Fiorini, E.1
Schmitz, I.2
Marissen, W.E.3
Osborn, S.L.4
Touma, M.5
Sasada, T.6
-
38
-
-
80054720856
-
Impaired B cell development and function in the absence of IκBNS
-
Touma M, Keskin DB, Shiroki F, Saito I, Koyasu S, Reinherz EL et al. Impaired B cell development and function in the absence of IκBNS. J Immunol 2011;187:3942–3952.
-
(2011)
J Immunol
, vol.187
, pp. 3942-3952
-
-
Touma, M.1
Keskin, D.B.2
Shiroki, F.3
Saito, I.4
Koyasu, S.5
Reinherz, E.L.6
-
39
-
-
84864502473
-
A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity
-
Arnold CN, Pirie E, Dosenovic P, McInerney GM, Xia Y, Wang N et al. A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity. Proc Natl Acad Sci USA 2012;109:12286–12293.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 12286-12293
-
-
Arnold, C.N.1
Pirie, E.2
Dosenovic, P.3
McInerney, G.M.4
Xia, Y.5
Wang, N.6
-
40
-
-
82155175243
-
IL-13-induced MUC5AC production and goblet cell differentiation is steroid resistant in human airway cells
-
Kanoh S, Tanabe T, Rubin BK. IL-13-induced MUC5AC production and goblet cell differentiation is steroid resistant in human airway cells. Clin Exp Allergy 2011;41:1747–1756.
-
(2011)
Clin Exp Allergy
, vol.41
, pp. 1747-1756
-
-
Kanoh, S.1
Tanabe, T.2
Rubin, B.K.3
-
41
-
-
84892563951
-
Muc5b is required for airway defence
-
Roy MG, Livraghi-Butrico A, Fletcher AA, McElwee MM, Evans SE, Boerner RM et al. Muc5b is required for airway defence. Nature 2014;505:412–416.
-
(2014)
Nature
, vol.505
, pp. 412-416
-
-
Roy, M.G.1
Livraghi-Butrico, A.2
Fletcher, A.A.3
McElwee, M.M.4
Evans, S.E.5
Boerner, R.M.6
|