C-Maf activates the promoter and enhancer of the IL-21 gene, and TGF-β inhibits c-Maf-induced IL-21 production in CD4+ T cells

Journal of Leukocyte Biology

Volumn 87, Issue 4, 2010, Pages 703-712

  Hiramatsu, Yukiko ^a,b   Suto, Akira ^a,b   Kashiwakuma, Daisuke ^a,b   Kanari, Hiroko ^a   Kagami, Shin Ichiro ^a,b   Ikeda, Kei ^b   Hirose, Koichi ^b   Watanabe, Norihiko ^b   Grusby, Michael J ^c   Iwamoto, Itsuo ^d   Nakajima, Hiroshi ^a,b  

^a CHIBA UNIVERSITY   (Japan)

^b CHIBA UNIVERSITY HOSPITAL   (Japan)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^d ASAHI GENERAL HOSPITAL   (Japan)

Author keywords

Foxp3; Tfh cells; Th17 cells; Tregs

Indexed keywords

CD4 ANTIGEN; INTERLEUKIN 21; INTERLEUKIN 6; TRANSCRIPTION FACTOR C MAF; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTOCRINE EFFECT; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE EXPRESSION; LYMPH NODE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INDUCTION; TH17 CELL; TRANSCRIPTION REGULATION; UPREGULATION;

ANIMALS; AUTOCRINE COMMUNICATION; CD4-POSITIVE T-LYMPHOCYTES; ENHANCER ELEMENTS, GENETIC; FORKHEAD TRANSCRIPTION FACTORS; INTERLEUKIN-4; INTERLEUKIN-6; INTERLEUKINS; MICE; MICE, INBRED BALB C; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS C-MAF; STAT6 TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION;

EID: 77950554986     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0909639     Document Type: Article

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