KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 50, 2016, Pages 14372-14377

  Schumann, Gunter ^a   Liu, Chunyu ^b,c,d   O'Reilly, Paul ^a   Gao, He ^e,f   Song, Parkyong ^g,h   Xu, Bing ^a   Ruggeri, Barbara ^a   Amin, Najaf ⁱ   Jia, Tianye ^a   Preis, Sarah ^d   Lepe, Marcelo Segura ^e,j   Akira, Shizuo ^k   Barbieri, Caterina ^l   Baumeister, Sebastian ^m,n   Cauchi, Stephane ^o   Clarke, Toni Kim ^p   Enroth, Stefan ^q   Fischer, Krista ^r   Hällfors, Jenni ^s   Harris, Sarah E ^p   Hieber, Saskia ^t   Hofer, Edith ^u   Hottenga, Jouke Jan ^v   Johansson, Åsa ^q   Joshi, Peter K ^w   Kaartinen, Niina ^x   Laitinen, Jaana ^y   Lemaitre, Rozenn ^z   Loukola, Anu ^s   Luan, Jian'an ^aa   Lyytikäinen, Leo Pekka ^ab   Mangino, Massimo ^ac,ad   Manichaikul, Ani ^ae,af   Mbarek, Hamdi ^v   Milaneschi, Yuri ^ag   Moayyeri, Alireza ^e,ah   Mukamal, Kenneth ^ai   Nelson, Christopher ^aj,ak   Nettleton, Jennifer ^al   Partinen, Eemil ^am   Rawal, Rajesh ^an   Robino, Antonietta ^ao   Rose, Lynda ^ap   Sala, Cinzia ^l   Satoh, Takashi ^k   Schmidt, Reinhold ^u   Schraut, Katharina ^w   Scott, Robert ^aa   Smith, Albert Vernon ^aq   Starr, John M ^p   Teumer, Alexander ^m   Trompet, Stella ^ar   Uitterlinden, André G ^i,ar   Venturini, Cristina ^al   Vergnaud, Anne Claire ^e   Verweij, Niek ^as   Vitart, Veronique ^at   Vuckovic, Dragana ^au   Wedenoja, Juho ^s   Yengo, Loic ^o   Yu, Bing ^al   Zhang, Weihua ^e,av   Zhao, Jing Hua ^am   Boomsma, Dorret I ^v   Chambers, John ^e,av,aw   Chasman, Daniel I ^ai,ak   Daniela, Toniolo ^l   De Geus, Eco ^v   Deary, Ian ^p   Eriksson, Johan G ^s,x,ax,ay,az   Esko, Tõnu ^r   Eulenburg, Volker ^t   Franco, Oscar H ⁱ   Froguel, Philippe ^e,o   Gieger, Christian ^an   Grabe, Hans J ^m   Gudnason, Vilmundur ^aq,ba   Gyllensten, Ulf ^q   Harris, Tamara B ^bb   Hartikainen, Anna Liisa ^bc,bd   Heath, Andrew C ^be   Hocking, Lynne ^bf   Hofman, Albert ⁱ   Huth, Cornelia ^an   Jarvelin, Marjo Riitta ^e,bc,bd,bg   Jukema, J Wouter ^ar   Kaprio, Jaakko ^s,x   Kooner, Jaspal S ^av,aw,bh   Kutalik, Zoltan ^bi   Lahti, Jari ^s,ay   Langenberg, Claudia ^aa   Lehtimäki, Terho ^ab   Liu, Yongmei ^bj   Madden, Pamela A F ^be   Martin, Nicholas ^bk   Morrison, Alanna ^al   Penninx, Brenda ^ag   Pirastu, Nicola ^z,au   Psaty, Bruce ^z,bl,bm   Raitakari, Olli ^bn,bo   Ridker, Paul ^ai,at   Rose, Richard ^bp   Rotter, Jerome I ^bq   Samani, Nilesh J ^aj,ak   Schmidt, Helena ^u   Spector, Tim D ^ac   Stott, David ^br   Strachan, David ^bs   Tzoulaki, Ioanna ^e,f,bt   Van Der Harst, Pim ^as,bu   Van Duijn, Cornelia M ⁱ   Marques Vidal, Pedro ^bv   Vollenweider, Peter ^bv   Wareham, Nicholas J ^aa   Whitfield, John B ^bk   Wilson, James ^w,at   Wolffenbuttel, Bruce ^as   Bakalkin, Georgy ^q   Evangelou, Evangelos ^e,bt   Liu, Yun ^bw,bx   Rice, Kenneth M ^bl   Desrivières, Sylvane ^a   Kliewer, Steven A ^g,h   Mangelsdorf, David J ^a,g,h   Müller, Christian P ^t   Levy, Daniel ^b,c   Elliott, Paul ^e,f   more..

^a KING'S COLLEGE LONDON   (United Kingdom)

^b FRAMINGHAM HEART STUDY   (United States)

^c NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^d BOSTON UNIVERSITY   (United States)

^e IMPERIAL COLLEGE LONDON   (United Kingdom)

^f PUBLIC HEALTH ENGLAND   (United Kingdom)

^g UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^h UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

ⁱ ERASMUS MEDICAL CENTER   (Netherlands)

^j BAYER PHARMA AG   (Germany)

^k OSAKA UNIVERSITY   (Japan)

^l SAN RAFFAELE HOSPITAL   (Italy)

^m UNIVERSITY MEDICINE GREIFSWALD   (Germany)

ⁿ UNIVERSITY OF REGENSBURG   (Germany)

^o Institut Pasteur de Lille   (France)

^p UNIVERSITY OF EDINBURGH   (United Kingdom)

^q UPPSALA UNIVERSITY   (Sweden)

^r UNIVERSITY OF TARTU   (Estonia)

^s UNIVERSITY OF HELSINKI   (Finland)

^t UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^u MEDICAL UNIVERSITY OF GRAZ   (Austria)

^v UNIVERSITY OF AMSTERDAM   (Netherlands)

^w UNIVERSITY OF EDINBURGH   (United Kingdom)

^x NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^y FINNISH INSTITUTE OF OCCUPATIONAL HEALTH   (Finland)

^z UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^aa UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^ab TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^ac KING'S COLLEGE LONDON   (United Kingdom)

^ad GUY'S AND ST THOMAS' NHS FOUNDATION TRUST   (United Kingdom)

^ae UNIVERSITY OF VIRGINIA   (United States)

^af UNIVERSITY OF VIRGINIA   (United States)

^ag ACADEMIC MEDICAL CENTER   (Netherlands)

^ah UNIVERSITY COLLEGE LONDON   (United Kingdom)

^ai HARVARD MEDICAL SCHOOL   (United States)

^aj UNIVERSITY OF LEICESTER   (United Kingdom)

^ak GLENFIELD HOSPITAL   (United Kingdom)

^al UNIVERSITY OF TEXAS   (United States)

^am UNIVERSITY OF TARTU   (Estonia)

^an INSTITUTE OF EPIDEMIOLOGY   (Germany)

^ao INSTITUTE FOR MATERNAL AND CHILD HEALTH IRCCS BURLO GAROFOLO   (Italy)

^ap BRIGHAM AND WOMEN S HOSPITAL   (United States)

^aq ICELANDIC HEART ASSOCIATION   (Iceland)

^ar LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^as UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^at UNIVERSITY OF EDINBURGH   (United Kingdom)

^au UNIVERSITY OF TRIESTE   (Italy)

^av EALING HOSPITAL   (United Kingdom)

^aw IMPERIAL COLLEGE HEALTHCARE NHS TRUST   (United Kingdom)

^ax HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^ay FOLKHÄLSAN RESEARCH CENTER   (Finland)

^az VAASA CENTRAL HOSPITAL   (Finland)

^ba UNIVERSITY OF ICELAND   (Iceland)

^bb NATIONAL INSTITUTE ON AGING   (United States)

^bc OULU UNIVERSITY HOSPITAL   (Finland)

^bd UNIVERSITY OF OULU   (Finland)

^be WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^bf UNIVERSITY OF ABERDEEN   (United Kingdom)

^bg UNIVERSITY OF OULU   (Finland)

^bh NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^bi UNIVERSITY OF LAUSANNE   (Switzerland)

^bj WAKE FOREST SCHOOL OF MEDICINE   (United States)

^bk QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^bl UNIVERSITY OF WASHINGTON   (United States)

^bm GROUP HEALTH RESEARCH INSTITUTE   (United States)

^bn TURKU UNIVERSITY HOSPITAL   (Finland)

^bo UNIVERSITY OF TURKU   (Finland)

^bp INDIANA UNIVERSITY   (United States)

^bq HARBOR UCLA MEDICAL CENTER   (United States)

^br UNIVERSITY OF GLASGOW   (United Kingdom)

^bs ST GEORGE S HOSPITAL   (United Kingdom)

^bt UNIVERSITY OF IOANNINA   (Greece)

^bu INTERUNIVERSITY CARDIOLOGY INSTITUTE OF THE NETHERLANDS   (Netherlands)

^bv LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^bw BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^bx FUDAN UNIVERSITY   (China)

more..

Author keywords

Alcohol consumption; FGF21; Human; Mouse model; Klotho

Indexed keywords

ALCOHOL; BETA KLOTHO PROTEIN; FIBROBLAST GROWTH FACTOR 21; KLOTHO PROTEIN; UNCLASSIFIED DRUG; FIBROBLAST GROWTH FACTOR; KLB PROTEIN, HUMAN; KLB PROTEIN, MOUSE; MEMBRANE PROTEIN;

ALCOHOL BLOOD LEVEL; ALCOHOL CONSUMPTION; ALCOHOL PREFERENCE; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; BRAIN; COHORT ANALYSIS; CONFERENCE PAPER; CONTROLLED STUDY; DRINKING BEHAVIOR; EMOTION; ENDOCRINE FUNCTION; EUROPEAN; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC ASSOCIATION; GENOME-WIDE ASSOCIATION STUDY; HUMAN; LIVER; LIVER BRAIN ENDOCRINE AXIS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; REPLICATION STUDY; SINGLE NUCLEOTIDE POLYMORPHISM; 129 MOUSE; ANIMAL; C57BL MOUSE; DEFICIENCY; GENETICS; KNOCKOUT MOUSE; META ANALYSIS; PATHOPHYSIOLOGY; PHYSIOLOGY;

ALCOHOL DRINKING; ANIMALS; BEHAVIOR, ANIMAL; BRAIN; EMOTIONS; FEMALE; FIBROBLAST GROWTH FACTORS; GENOME-WIDE ASSOCIATION STUDY; HUMANS; LIVER; MALE; MEMBRANE PROTEINS; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 85006055058     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1611243113     Document Type: Article

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