-
2
-
-
84880801392
-
Talins and kindlins: partners in integrin-mediated adhesion
-
Calderwood, D.A., Campbell, I.D., Critchley, D.R., Talins and kindlins: partners in integrin-mediated adhesion. Nat. Rev. Mol. Cell Biol. 14 (2013), 503–517.
-
(2013)
Nat. Rev. Mol. Cell Biol.
, vol.14
, pp. 503-517
-
-
Calderwood, D.A.1
Campbell, I.D.2
Critchley, D.R.3
-
3
-
-
84861206592
-
CD98 at the crossroads of adaptive immunity and cancer
-
Cantor, J.M., Ginsberg, M.H., CD98 at the crossroads of adaptive immunity and cancer. J. Cell Sci. 125 (2012), 1373–1382.
-
(2012)
J. Cell Sci.
, vol.125
, pp. 1373-1382
-
-
Cantor, J.M.1
Ginsberg, M.H.2
-
4
-
-
47249143701
-
Integrin-associated proteins as potential therapeutic targets
-
Cantor, J.M., Ginsberg, M.H., Rose, D.M., Integrin-associated proteins as potential therapeutic targets. Immunol. Rev. 223 (2008), 236–251.
-
(2008)
Immunol. Rev.
, vol.223
, pp. 236-251
-
-
Cantor, J.M.1
Ginsberg, M.H.2
Rose, D.M.3
-
5
-
-
62849128302
-
CD98hc facilitates B cell proliferation and adaptive humoral immunity
-
Cantor, J., Browne, C.D., Ruppert, R., Feral, C.C., Fassler, R., Rickert, R.C., Ginsberg, M.H., CD98hc facilitates B cell proliferation and adaptive humoral immunity. Nat. Immunol. 10 (2009), 412–419.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 412-419
-
-
Cantor, J.1
Browne, C.D.2
Ruppert, R.3
Feral, C.C.4
Fassler, R.5
Rickert, R.C.6
Ginsberg, M.H.7
-
6
-
-
79960481517
-
Loss of T cell CD98 H chain specifically ablates T cell clonal expansion and protects from autoimmunity
-
Cantor, J., Slepak, M., Ege, N., Chang, J.T., Ginsberg, M.H., Loss of T cell CD98 H chain specifically ablates T cell clonal expansion and protects from autoimmunity. J. Immunol. 187 (2011), 851–860.
-
(2011)
J. Immunol.
, vol.187
, pp. 851-860
-
-
Cantor, J.1
Slepak, M.2
Ege, N.3
Chang, J.T.4
Ginsberg, M.H.5
-
7
-
-
72949119124
-
Integrins in cancer: biological implications and therapeutic opportunities
-
Desgrosellier, J.S., Cheresh, D.A., Integrins in cancer: biological implications and therapeutic opportunities. Nat. Rev. Cancer 10 (2010), 9–22.
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 9-22
-
-
Desgrosellier, J.S.1
Cheresh, D.A.2
-
8
-
-
70350574674
-
An integrin alpha(v)beta(3)-c-Src oncogenic unit promotes anchorage-independence and tumor progression
-
Desgrosellier, J.S., Barnes, L.A., Shields, D.J., Huang, M., Lau, S.K., Prevost, N., Tarin, D., Shattil, S.J., Cheresh, D.A., An integrin alpha(v)beta(3)-c-Src oncogenic unit promotes anchorage-independence and tumor progression. Nat. Med. 15 (2009), 1163–1169.
-
(2009)
Nat. Med.
, vol.15
, pp. 1163-1169
-
-
Desgrosellier, J.S.1
Barnes, L.A.2
Shields, D.J.3
Huang, M.4
Lau, S.K.5
Prevost, N.6
Tarin, D.7
Shattil, S.J.8
Cheresh, D.A.9
-
9
-
-
84864374811
-
Focal adhesion kinase splice variants maintain primitive acute myeloid leukemia cells through altered Wnt signaling
-
Despeaux, M., Chicanne, G., Rouer, E., De Toni-Costes, F., Bertrand, J., Mansat-De Mas, V., Vergnolle, N., Eaves, C., Payrastre, B., Girault, J.A., et al. Focal adhesion kinase splice variants maintain primitive acute myeloid leukemia cells through altered Wnt signaling. Stem Cells 30 (2012), 1597–1610.
-
(2012)
Stem Cells
, vol.30
, pp. 1597-1610
-
-
Despeaux, M.1
Chicanne, G.2
Rouer, E.3
De Toni-Costes, F.4
Bertrand, J.5
Mansat-De Mas, V.6
Vergnolle, N.7
Eaves, C.8
Payrastre, B.9
Girault, J.A.10
-
10
-
-
84856147560
-
Endothelial and perivascular cells maintain haematopoietic stem cells
-
Ding, L., Saunders, T.L., Enikolopov, G., Morrison, S.J., Endothelial and perivascular cells maintain haematopoietic stem cells. Nature 481 (2012), 457–462.
-
(2012)
Nature
, vol.481
, pp. 457-462
-
-
Ding, L.1
Saunders, T.L.2
Enikolopov, G.3
Morrison, S.J.4
-
11
-
-
34548138930
-
Autocrine insulin-like growth factor-I signaling promotes growth and survival of human acute myeloid leukemia cells via the phosphoinositide 3-kinase/Akt pathway
-
Doepfner, K.T., Spertini, O., Arcaro, A., Autocrine insulin-like growth factor-I signaling promotes growth and survival of human acute myeloid leukemia cells via the phosphoinositide 3-kinase/Akt pathway. Leukemia 21 (2007), 1921–1930.
-
(2007)
Leukemia
, vol.21
, pp. 1921-1930
-
-
Doepfner, K.T.1
Spertini, O.2
Arcaro, A.3
-
12
-
-
84917709109
-
CD98hc (SLC3A2) loss protects against ras-driven tumorigenesis by modulating integrin-mediated mechanotransduction
-
Estrach, S., Lee, S.A., Boulter, E., Pisano, S., Errante, A., Tissot, F.S., Cailleteau, L., Pons, C., Ginsberg, M.H., Feral, C.C., CD98hc (SLC3A2) loss protects against ras-driven tumorigenesis by modulating integrin-mediated mechanotransduction. Cancer Res. 74 (2014), 6878–6889.
-
(2014)
Cancer Res.
, vol.74
, pp. 6878-6889
-
-
Estrach, S.1
Lee, S.A.2
Boulter, E.3
Pisano, S.4
Errante, A.5
Tissot, F.S.6
Cailleteau, L.7
Pons, C.8
Ginsberg, M.H.9
Feral, C.C.10
-
13
-
-
0030710958
-
Complementation of dominant suppression implicates CD98 in integrin activation
-
Fenczik, C.A., Sethi, T., Ramos, J.W., Hughes, P.E., Ginsberg, M.H., Complementation of dominant suppression implicates CD98 in integrin activation. Nature 390 (1997), 81–85.
-
(1997)
Nature
, vol.390
, pp. 81-85
-
-
Fenczik, C.A.1
Sethi, T.2
Ramos, J.W.3
Hughes, P.E.4
Ginsberg, M.H.5
-
14
-
-
0035937759
-
Distinct domains of CD98hc regulate integrins and amino acid transport
-
Fenczik, C.A., Zent, R., Dellos, M., Calderwood, D.A., Satriano, J., Kelly, C., Ginsberg, M.H., Distinct domains of CD98hc regulate integrins and amino acid transport. J. Biol. Chem. 276 (2001), 8746–8752.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 8746-8752
-
-
Fenczik, C.A.1
Zent, R.2
Dellos, M.3
Calderwood, D.A.4
Satriano, J.5
Kelly, C.6
Ginsberg, M.H.7
-
15
-
-
12244253041
-
CD98hc (SLC3A2) mediates integrin signaling
-
Feral, C.C., Nishiya, N., Fenczik, C.A., Stuhlmann, H., Slepak, M., Ginsberg, M.H., CD98hc (SLC3A2) mediates integrin signaling. Proc. Natl. Acad. Sci. USA 102 (2005), 355–360.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 355-360
-
-
Feral, C.C.1
Nishiya, N.2
Fenczik, C.A.3
Stuhlmann, H.4
Slepak, M.5
Ginsberg, M.H.6
-
16
-
-
34547938735
-
CD98hc (SLC3A2) participates in fibronectin matrix assembly by mediating integrin signaling
-
Feral, C.C., Zijlstra, A., Tkachenko, E., Prager, G., Gardel, M.L., Slepak, M., Ginsberg, M.H., CD98hc (SLC3A2) participates in fibronectin matrix assembly by mediating integrin signaling. J. Cell Biol. 178 (2007), 701–711.
-
(2007)
J. Cell Biol.
, vol.178
, pp. 701-711
-
-
Feral, C.C.1
Zijlstra, A.2
Tkachenko, E.3
Prager, G.4
Gardel, M.L.5
Slepak, M.6
Ginsberg, M.H.7
-
17
-
-
84976328190
-
Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma
-
Fox, R.G., Lytle, N.K., Jaquish, D.V., Park, F.D., Ito, T., Bajaj, J., Koechlein, C.S., Zimdahl, B., Yano, M., Kopp, J.L., et al. Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma. Nature 534 (2016), 407–411.
-
(2016)
Nature
, vol.534
, pp. 407-411
-
-
Fox, R.G.1
Lytle, N.K.2
Jaquish, D.V.3
Park, F.D.4
Ito, T.5
Bajaj, J.6
Koechlein, C.S.7
Zimdahl, B.8
Yano, M.9
Kopp, J.L.10
-
18
-
-
0035886024
-
Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells
-
Guzman, M.L., Neering, S.J., Upchurch, D., Grimes, B., Howard, D.S., Rizzieri, D.A., Luger, S.M., Jordan, C.T., Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells. Blood 98 (2001), 2301–2307.
-
(2001)
Blood
, vol.98
, pp. 2301-2307
-
-
Guzman, M.L.1
Neering, S.J.2
Upchurch, D.3
Grimes, B.4
Howard, D.S.5
Rizzieri, D.A.6
Luger, S.M.7
Jordan, C.T.8
-
19
-
-
0033533553
-
Malignant transformation of NIH3T3 cells by overexpression of early lymphocyte activation antigen CD98
-
Hara, K., Kudoh, H., Enomoto, T., Hashimoto, Y., Masuko, T., Malignant transformation of NIH3T3 cells by overexpression of early lymphocyte activation antigen CD98. Biochem. Biophys. Res. Commun. 262 (1999), 720–725.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.262
, pp. 720-725
-
-
Hara, K.1
Kudoh, H.2
Enomoto, T.3
Hashimoto, Y.4
Masuko, T.5
-
20
-
-
84929503111
-
Antitumor activity of an anti-CD98 antibody
-
Hayes, G.M., Chinn, L., Cantor, J.M., Cairns, B., Levashova, Z., Tran, H., Velilla, T., Duey, D., Lippincott, J., Zachwieja, J., et al. Antitumor activity of an anti-CD98 antibody. Int. J. Cancer 137 (2014), 710–720.
-
(2014)
Int. J. Cancer
, vol.137
, pp. 710-720
-
-
Hayes, G.M.1
Chinn, L.2
Cantor, J.M.3
Cairns, B.4
Levashova, Z.5
Tran, H.6
Velilla, T.7
Duey, D.8
Lippincott, J.9
Zachwieja, J.10
-
21
-
-
0019458324
-
Characterization of a monoclonal antibody (4F2) that binds to human monocytes and to a subset of activated lymphocytes
-
Haynes, B.F., Hemler, M.E., Mann, D.L., Eisenbarth, G.S., Shelhamer, J., Mostowski, H.S., Thomas, C.A., Strominger, J.L., Fauci, A.S., Characterization of a monoclonal antibody (4F2) that binds to human monocytes and to a subset of activated lymphocytes. J. Immunol. 126 (1981), 1409–1414.
-
(1981)
J. Immunol.
, vol.126
, pp. 1409-1414
-
-
Haynes, B.F.1
Hemler, M.E.2
Mann, D.L.3
Eisenbarth, G.S.4
Shelhamer, J.5
Mostowski, H.S.6
Thomas, C.A.7
Strominger, J.L.8
Fauci, A.S.9
-
22
-
-
11144242444
-
CD98hc (SLC3A2) interaction with beta 1 integrins is required for transformation
-
Henderson, N.C., Collis, E.A., Mackinnon, A.C., Simpson, K.J., Haslett, C., Zent, R., Ginsberg, M., Sethi, T., CD98hc (SLC3A2) interaction with beta 1 integrins is required for transformation. J. Biol. Chem. 279 (2004), 54731–54741.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 54731-54741
-
-
Henderson, N.C.1
Collis, E.A.2
Mackinnon, A.C.3
Simpson, K.J.4
Haslett, C.5
Zent, R.6
Ginsberg, M.7
Sethi, T.8
-
23
-
-
78751476207
-
Inhibition of L-type amino acid transporter 1 has antitumor activity in non-small cell lung cancer
-
Imai, H., Kaira, K., Oriuchi, N., Shimizu, K., Tominaga, H., Yanagitani, N., Sunaga, N., Ishizuka, T., Nagamori, S., Promchan, K., et al. Inhibition of L-type amino acid transporter 1 has antitumor activity in non-small cell lung cancer. Anticancer Res. 30 (2010), 4819–4828.
-
(2010)
Anticancer Res.
, vol.30
, pp. 4819-4828
-
-
Imai, H.1
Kaira, K.2
Oriuchi, N.3
Shimizu, K.4
Tominaga, H.5
Yanagitani, N.6
Sunaga, N.7
Ishizuka, T.8
Nagamori, S.9
Promchan, K.10
-
24
-
-
84902106468
-
Reciprocal leukemia-stroma VCAM-1/VLA-4-dependent activation of NF-kappaB mediates chemoresistance
-
Jacamo, R., Chen, Y., Wang, Z., Ma, W., Zhang, M., Spaeth, E.L., Wang, Y., Battula, V.L., Mak, P.Y., Schallmoser, K., et al. Reciprocal leukemia-stroma VCAM-1/VLA-4-dependent activation of NF-kappaB mediates chemoresistance. Blood 123 (2014), 2691–2702.
-
(2014)
Blood
, vol.123
, pp. 2691-2702
-
-
Jacamo, R.1
Chen, Y.2
Wang, Z.3
Ma, W.4
Zhang, M.5
Spaeth, E.L.6
Wang, Y.7
Battula, V.L.8
Mak, P.Y.9
Schallmoser, K.10
-
25
-
-
33749515476
-
Targeting of CD44 eradicates human acute myeloid leukemic stem cells
-
Jin, L., Hope, K.J., Zhai, Q., Smadja-Joffe, F., Dick, J.E., Targeting of CD44 eradicates human acute myeloid leukemic stem cells. Nat. Med. 12 (2006), 1167–1174.
-
(2006)
Nat. Med.
, vol.12
, pp. 1167-1174
-
-
Jin, L.1
Hope, K.J.2
Zhai, Q.3
Smadja-Joffe, F.4
Dick, J.E.5
-
26
-
-
84979081969
-
High-resolution imaging and computational analysis of haematopoietic cell dynamics in vivo
-
Koechlein, C.S., Harris, J.R., Lee, T.K., Weeks, J., Fox, R.G., Zimdahl, B., Ito, T., Blevins, A., Jung, S.H., Chute, J.P., et al. High-resolution imaging and computational analysis of haematopoietic cell dynamics in vivo. Nat. Commun., 7, 2016, 12169.
-
(2016)
Nat. Commun.
, vol.7
, pp. 12169
-
-
Koechlein, C.S.1
Harris, J.R.2
Lee, T.K.3
Weeks, J.4
Fox, R.G.5
Zimdahl, B.6
Ito, T.7
Blevins, A.8
Jung, S.H.9
Chute, J.P.10
-
27
-
-
79952092993
-
Leukemia stem cells and microenvironment: biology and therapeutic targeting
-
Konopleva, M.Y., Jordan, C.T., Leukemia stem cells and microenvironment: biology and therapeutic targeting. J. Clin. Oncol. 29 (2011), 591–599.
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 591-599
-
-
Konopleva, M.Y.1
Jordan, C.T.2
-
28
-
-
35548934558
-
MLL translocations, histone modifications and leukaemia stem-cell development
-
Krivtsov, A.V., Armstrong, S.A., MLL translocations, histone modifications and leukaemia stem-cell development. Nat. Rev. Cancer 7 (2007), 823–833.
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 823-833
-
-
Krivtsov, A.V.1
Armstrong, S.A.2
-
29
-
-
84886947010
-
Arteriolar niches maintain haematopoietic stem cell quiescence
-
Kunisaki, Y., Bruns, I., Scheiermann, C., Ahmed, J., Pinho, S., Zhang, D., Mizoguchi, T., Wei, Q., Lucas, D., Ito, K., et al. Arteriolar niches maintain haematopoietic stem cell quiescence. Nature 502 (2013), 637–643.
-
(2013)
Nature
, vol.502
, pp. 637-643
-
-
Kunisaki, Y.1
Bruns, I.2
Scheiermann, C.3
Ahmed, J.4
Pinho, S.5
Zhang, D.6
Mizoguchi, T.7
Wei, Q.8
Lucas, D.9
Ito, K.10
-
30
-
-
84938741455
-
Tetraspanin 3 is required for the development and propagation of acute myelogenous leukemia
-
Kwon, H.Y., Bajaj, J., Ito, T., Blevins, A., Konuma, T., Weeks, J., Lytle, N.K., Koechlein, C.S., Rizzieri, D., Chuah, C., et al. Tetraspanin 3 is required for the development and propagation of acute myelogenous leukemia. Cell Stem Cell 17 (2015), 152–164.
-
(2015)
Cell Stem Cell
, vol.17
, pp. 152-164
-
-
Kwon, H.Y.1
Bajaj, J.2
Ito, T.3
Blevins, A.4
Konuma, T.5
Weeks, J.6
Lytle, N.K.7
Koechlein, C.S.8
Rizzieri, D.9
Chuah, C.10
-
31
-
-
80052674328
-
Differential niche and Wnt requirements during acute myeloid leukemia progression
-
Lane, S.W., Wang, Y.J., Lo Celso, C., Ragu, C., Bullinger, L., Sykes, S.M., Ferraro, F., Shterental, S., Lin, C.P., Gilliland, D.G., et al. Differential niche and Wnt requirements during acute myeloid leukemia progression. Blood 118 (2011), 2849–2856.
-
(2011)
Blood
, vol.118
, pp. 2849-2856
-
-
Lane, S.W.1
Wang, Y.J.2
Lo Celso, C.3
Ragu, C.4
Bullinger, L.5
Sykes, S.M.6
Ferraro, F.7
Shterental, S.8
Lin, C.P.9
Gilliland, D.G.10
-
32
-
-
84904994417
-
Stromal response to Hedgehog signaling restrains pancreatic cancer progression
-
Lee, J.J., Perera, R.M., Wang, H., Wu, D.C., Liu, X.S., Han, S., Fitamant, J., Jones, P.D., Ghanta, K.S., Kawano, S., et al. Stromal response to Hedgehog signaling restrains pancreatic cancer progression. Proc. Natl. Acad. Sci. USA 111 (2014), E3091–E3100.
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. E3091-E3100
-
-
Lee, J.J.1
Perera, R.M.2
Wang, H.3
Wu, D.C.4
Liu, X.S.5
Han, S.6
Fitamant, J.7
Jones, P.D.8
Ghanta, K.S.9
Kawano, S.10
-
33
-
-
0141461414
-
Interaction between leukemic-cell VLA-4 and stromal fibronectin is a decisive factor for minimal residual disease of acute myelogenous leukemia
-
Matsunaga, T., Takemoto, N., Sato, T., Takimoto, R., Tanaka, I., Fujimi, A., Akiyama, T., Kuroda, H., Kawano, Y., Kobune, M., et al. Interaction between leukemic-cell VLA-4 and stromal fibronectin is a decisive factor for minimal residual disease of acute myelogenous leukemia. Nat. Med. 9 (2003), 1158–1165.
-
(2003)
Nat. Med.
, vol.9
, pp. 1158-1165
-
-
Matsunaga, T.1
Takemoto, N.2
Sato, T.3
Takimoto, R.4
Tanaka, I.5
Fujimi, A.6
Akiyama, T.7
Kuroda, H.8
Kawano, Y.9
Kobune, M.10
-
34
-
-
0034823632
-
Therapeutic targeting of the MEK/MAPK signal transduction module in acute myeloid leukemia
-
Milella, M., Kornblau, S.M., Estrov, Z., Carter, B.Z., Lapillonne, H., Harris, D., Konopleva, M., Zhao, S., Estey, E., Andreeff, M., Therapeutic targeting of the MEK/MAPK signal transduction module in acute myeloid leukemia. J. Clin. Invest. 108 (2001), 851–859.
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 851-859
-
-
Milella, M.1
Kornblau, S.M.2
Estrov, Z.3
Carter, B.Z.4
Lapillonne, H.5
Harris, D.6
Konopleva, M.7
Zhao, S.8
Estey, E.9
Andreeff, M.10
-
35
-
-
84880011146
-
In vivo RNAi screening identifies a leukemia-specific dependence on integrin beta 3 signaling
-
Miller, P.G., Al-Shahrour, F., Hartwell, K.A., Chu, L.P., Jaras, M., Puram, R.V., Puissant, A., Callahan, K.P., Ashton, J., McConkey, M.E., et al. In vivo RNAi screening identifies a leukemia-specific dependence on integrin beta 3 signaling. Cancer Cell 24 (2013), 45–58.
-
(2013)
Cancer Cell
, vol.24
, pp. 45-58
-
-
Miller, P.G.1
Al-Shahrour, F.2
Hartwell, K.A.3
Chu, L.P.4
Jaras, M.5
Puram, R.V.6
Puissant, A.7
Callahan, K.P.8
Ashton, J.9
McConkey, M.E.10
-
36
-
-
84859820567
-
Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance
-
Nakasone, E.S., Askautrud, H.A., Kees, T., Park, J.H., Plaks, V., Ewald, A.J., Fein, M., Rasch, M.G., Tan, Y.X., Qiu, J., et al. Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance. Cancer Cell 21 (2012), 488–503.
-
(2012)
Cancer Cell
, vol.21
, pp. 488-503
-
-
Nakasone, E.S.1
Askautrud, H.A.2
Kees, T.3
Park, J.H.4
Plaks, V.5
Ewald, A.J.6
Fein, M.7
Rasch, M.G.8
Tan, Y.X.9
Qiu, J.10
-
37
-
-
79955485553
-
CD98 expression modulates intestinal homeostasis, inflammation, and colitis-associated cancer in mice
-
Nguyen, H.T., Dalmasso, G., Torkvist, L., Halfvarson, J., Yan, Y., Laroui, H., Shmerling, D., Tallone, T., D'Amato, M., Sitaraman, S.V., et al. CD98 expression modulates intestinal homeostasis, inflammation, and colitis-associated cancer in mice. J. Clin. Invest. 121 (2011), 1733–1747.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 1733-1747
-
-
Nguyen, H.T.1
Dalmasso, G.2
Torkvist, L.3
Halfvarson, J.4
Yan, Y.5
Laroui, H.6
Shmerling, D.7
Tallone, T.8
D'Amato, M.9
Sitaraman, S.V.10
-
38
-
-
18844428327
-
Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
-
Orimo, A., Gupta, P.B., Sgroi, D.C., Arenzana-Seisdedos, F., Delaunay, T., Naeem, R., Carey, V.J., Richardson, A.L., Weinberg, R.A., Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 121 (2005), 335–348.
-
(2005)
Cell
, vol.121
, pp. 335-348
-
-
Orimo, A.1
Gupta, P.B.2
Sgroi, D.C.3
Arenzana-Seisdedos, F.4
Delaunay, T.5
Naeem, R.6
Carey, V.J.7
Richardson, A.L.8
Weinberg, R.A.9
-
39
-
-
84902469661
-
Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival
-
Ozdemir, B.C., Pentcheva-Hoang, T., Carstens, J.L., Zheng, X., Wu, C.C., Simpson, T.R., Laklai, H., Sugimoto, H., Kahlert, C., Novitskiy, S.V., et al. Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival. Cancer Cell 25 (2014), 719–734.
-
(2014)
Cancer Cell
, vol.25
, pp. 719-734
-
-
Ozdemir, B.C.1
Pentcheva-Hoang, T.2
Carstens, J.L.3
Zheng, X.4
Wu, C.C.5
Simpson, T.R.6
Laklai, H.7
Sugimoto, H.8
Kahlert, C.9
Novitskiy, S.V.10
-
40
-
-
84924028133
-
Musashi2 sustains the mixed-lineage leukemia-driven stem cell regulatory program
-
Park, S.M., Gonen, M., Vu, L., Minuesa, G., Tivnan, P., Barlowe, T.S., Taggart, J., Lu, Y., Deering, R.P., Hacohen, N., et al. Musashi2 sustains the mixed-lineage leukemia-driven stem cell regulatory program. J. Clin. Invest. 125 (2015), 1286–1298.
-
(2015)
J. Clin. Invest.
, vol.125
, pp. 1286-1298
-
-
Park, S.M.1
Gonen, M.2
Vu, L.3
Minuesa, G.4
Tivnan, P.5
Barlowe, T.S.6
Taggart, J.7
Lu, Y.8
Deering, R.P.9
Hacohen, N.10
-
41
-
-
0026738947
-
Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells
-
Petersen, O.W., Ronnov-Jessen, L., Howlett, A.R., Bissell, M.J., Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells. Proc. Natl. Acad. Sci. USA 89 (1992), 9064–9068.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 9064-9068
-
-
Petersen, O.W.1
Ronnov-Jessen, L.2
Howlett, A.R.3
Bissell, M.J.4
-
42
-
-
84902435628
-
Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma
-
Rhim, A.D., Oberstein, P.E., Thomas, D.H., Mirek, E.T., Palermo, C.F., Sastra, S.A., Dekleva, E.N., Saunders, T., Becerra, C.P., Tattersall, I.W., et al. Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma. Cancer Cell 25 (2014), 735–747.
-
(2014)
Cancer Cell
, vol.25
, pp. 735-747
-
-
Rhim, A.D.1
Oberstein, P.E.2
Thomas, D.H.3
Mirek, E.T.4
Palermo, C.F.5
Sastra, S.A.6
Dekleva, E.N.7
Saunders, T.8
Becerra, C.P.9
Tattersall, I.W.10
-
43
-
-
84930571933
-
L-type amino-acid transporter 1 (LAT1): a therapeutic target supporting growth and survival of T-cell lymphoblastic lymphoma/T-cell acute lymphoblastic leukemia
-
Rosilio, C., Nebout, M., Imbert, V., Griessinger, E., Neffati, Z., Benadiba, J., Hagenbeek, T., Spits, H., Reverso, J., Ambrosetti, D., et al. L-type amino-acid transporter 1 (LAT1): a therapeutic target supporting growth and survival of T-cell lymphoblastic lymphoma/T-cell acute lymphoblastic leukemia. Leukemia 29 (2014), 1253–1266.
-
(2014)
Leukemia
, vol.29
, pp. 1253-1266
-
-
Rosilio, C.1
Nebout, M.2
Imbert, V.3
Griessinger, E.4
Neffati, Z.5
Benadiba, J.6
Hagenbeek, T.7
Spits, H.8
Reverso, J.9
Ambrosetti, D.10
-
44
-
-
84925664997
-
Integrins and cancer: regulators of cancer stemness, metastasis, and drug resistance
-
Seguin, L., Desgrosellier, J.S., Weis, S.M., Cheresh, D.A., Integrins and cancer: regulators of cancer stemness, metastasis, and drug resistance. Trends Cell Biol. 25 (2015), 234–240.
-
(2015)
Trends Cell Biol.
, vol.25
, pp. 234-240
-
-
Seguin, L.1
Desgrosellier, J.S.2
Weis, S.M.3
Cheresh, D.A.4
-
45
-
-
55249114168
-
Inhibition of system L (LAT1/CD98hc) reduces the growth of cultured human breast cancer cells
-
Shennan, D.B., Thomson, J., Inhibition of system L (LAT1/CD98hc) reduces the growth of cultured human breast cancer cells. Oncol. Rep. 20 (2008), 885–889.
-
(2008)
Oncol. Rep.
, vol.20
, pp. 885-889
-
-
Shennan, D.B.1
Thomson, J.2
-
46
-
-
84874106911
-
The Polycomb complex PRC2 supports aberrant self-renewal in a mouse model of MLL-AF9;Nras(G12D) acute myeloid leukemia
-
Shi, J., Wang, E., Zuber, J., Rappaport, A., Taylor, M., Johns, C., Lowe, S.W., Vakoc, C.R., The Polycomb complex PRC2 supports aberrant self-renewal in a mouse model of MLL-AF9;Nras(G12D) acute myeloid leukemia. Oncogene 32 (2013), 930–938.
-
(2013)
Oncogene
, vol.32
, pp. 930-938
-
-
Shi, J.1
Wang, E.2
Zuber, J.3
Rappaport, A.4
Taylor, M.5
Johns, C.6
Lowe, S.W.7
Vakoc, C.R.8
-
47
-
-
84874714149
-
MLL-rearranged acute lymphoblastic leukaemia stem cell interactions with bone marrow stroma promote survival and therapeutic resistance that can be overcome with CXCR4 antagonism
-
Sison, E.A., Rau, R.E., McIntyre, E., Li, L., Small, D., Brown, P., MLL-rearranged acute lymphoblastic leukaemia stem cell interactions with bone marrow stroma promote survival and therapeutic resistance that can be overcome with CXCR4 antagonism. Br. J. Haematol. 160 (2013), 785–797.
-
(2013)
Br. J. Haematol.
, vol.160
, pp. 785-797
-
-
Sison, E.A.1
Rau, R.E.2
McIntyre, E.3
Li, L.4
Small, D.5
Brown, P.6
-
48
-
-
33749440584
-
Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia
-
Somervaille, T.C., Cleary, M.L., Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia. Cancer Cell 10 (2006), 257–268.
-
(2006)
Cancer Cell
, vol.10
, pp. 257-268
-
-
Somervaille, T.C.1
Cleary, M.L.2
-
49
-
-
58949102947
-
Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells
-
Somervaille, T.C., Matheny, C.J., Spencer, G.J., Iwasaki, M., Rinn, J.L., Witten, D.M., Chang, H.Y., Shurtleff, S.A., Downing, J.R., Cleary, M.L., Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells. Cell Stem Cell 4 (2009), 129–140.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 129-140
-
-
Somervaille, T.C.1
Matheny, C.J.2
Spencer, G.J.3
Iwasaki, M.4
Rinn, J.L.5
Witten, D.M.6
Chang, H.Y.7
Shurtleff, S.A.8
Downing, J.R.9
Cleary, M.L.10
-
50
-
-
0026693954
-
Regulation of vascular cell adhesion molecule 1 on human dermal microvascular endothelial cells
-
Swerlick, R.A., Lee, K.H., Li, L.J., Sepp, N.T., Caughman, S.W., Lawley, T.J., Regulation of vascular cell adhesion molecule 1 on human dermal microvascular endothelial cells. J. Immunol. 149 (1992), 698–705.
-
(1992)
J. Immunol.
, vol.149
, pp. 698-705
-
-
Swerlick, R.A.1
Lee, K.H.2
Li, L.J.3
Sepp, N.T.4
Caughman, S.W.5
Lawley, T.J.6
-
51
-
-
13744255245
-
CXCR4 regulates migration and development of human acute myelogenous leukemia stem cells in transplanted NOD/SCID mice
-
Tavor, S., Petit, I., Porozov, S., Avigdor, A., Dar, A., Leider-Trejo, L., Shemtov, N., Deutsch, V., Naparstek, E., Nagler, A., et al. CXCR4 regulates migration and development of human acute myelogenous leukemia stem cells in transplanted NOD/SCID mice. Cancer Res. 64 (2004), 2817–2824.
-
(2004)
Cancer Res.
, vol.64
, pp. 2817-2824
-
-
Tavor, S.1
Petit, I.2
Porozov, S.3
Avigdor, A.4
Dar, A.5
Leider-Trejo, L.6
Shemtov, N.7
Deutsch, V.8
Naparstek, E.9
Nagler, A.10
-
52
-
-
41349095906
-
RNAi screening of the tyrosine kinome identifies therapeutic targets in acute myeloid leukemia
-
Tyner, J.W., Walters, D.K., Willis, S.G., Luttropp, M., Oost, J., Loriaux, M., Erickson, H., Corbin, A.S., O'Hare, T., Heinrich, M.C., et al. RNAi screening of the tyrosine kinome identifies therapeutic targets in acute myeloid leukemia. Blood 111 (2008), 2238–2245.
-
(2008)
Blood
, vol.111
, pp. 2238-2245
-
-
Tyner, J.W.1
Walters, D.K.2
Willis, S.G.3
Luttropp, M.4
Oost, J.5
Loriaux, M.6
Erickson, H.7
Corbin, A.S.8
O'Hare, T.9
Heinrich, M.C.10
-
53
-
-
77950287628
-
The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML
-
Wang, Y., Krivtsov, A.V., Sinha, A.U., North, T.E., Goessling, W., Feng, Z., Zon, L.I., Armstrong, S.A., The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML. Science 327 (2010), 1650–1653.
-
(2010)
Science
, vol.327
, pp. 1650-1653
-
-
Wang, Y.1
Krivtsov, A.V.2
Sinha, A.U.3
North, T.E.4
Goessling, W.5
Feng, Z.6
Zon, L.I.7
Armstrong, S.A.8
-
54
-
-
0042744837
-
Survival of acute myeloid leukemia cells requires PI3 kinase activation
-
Xu, Q., Simpson, S.E., Scialla, T.J., Bagg, A., Carroll, M., Survival of acute myeloid leukemia cells requires PI3 kinase activation. Blood 102 (2003), 972–980.
-
(2003)
Blood
, vol.102
, pp. 972-980
-
-
Xu, Q.1
Simpson, S.E.2
Scialla, T.J.3
Bagg, A.4
Carroll, M.5
-
55
-
-
0022550772
-
Inhibition of tumor cell growth in vitro by murine monoclonal antibodies that recognize a proliferation-associated cell surface antigen system in rats and humans
-
Yagita, H., Masuko, T., Hashimoto, Y., Inhibition of tumor cell growth in vitro by murine monoclonal antibodies that recognize a proliferation-associated cell surface antigen system in rats and humans. Cancer Res. 46 (1986), 1478–1484.
-
(1986)
Cancer Res.
, vol.46
, pp. 1478-1484
-
-
Yagita, H.1
Masuko, T.2
Hashimoto, Y.3
-
56
-
-
0034681366
-
Class- and splice variant-specific association of CD98 with integrin beta cytoplasmic domains
-
Zent, R., Fenczik, C.A., Calderwood, D.A., Liu, S., Dellos, M., Ginsberg, M.H., Class- and splice variant-specific association of CD98 with integrin beta cytoplasmic domains. J. Biol. Chem. 275 (2000), 5059–5064.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 5059-5064
-
-
Zent, R.1
Fenczik, C.A.2
Calderwood, D.A.3
Liu, S.4
Dellos, M.5
Ginsberg, M.H.6
-
57
-
-
84895878922
-
Lis1 regulates asymmetric division in hematopoietic stem cells and in leukemia
-
Zimdahl, B., Ito, T., Blevins, A., Bajaj, J., Konuma, T., Weeks, J., Koechlein, C.S., Kwon, H.Y., Arami, O., Rizzieri, D., et al. Lis1 regulates asymmetric division in hematopoietic stem cells and in leukemia. Nat. Genet. 46 (2014), 245–252.
-
(2014)
Nat. Genet.
, vol.46
, pp. 245-252
-
-
Zimdahl, B.1
Ito, T.2
Blevins, A.3
Bajaj, J.4
Konuma, T.5
Weeks, J.6
Koechlein, C.S.7
Kwon, H.Y.8
Arami, O.9
Rizzieri, D.10
-
58
-
-
80055000824
-
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
-
Zuber, J., Shi, J., Wang, E., Rappaport, A.R., Herrmann, H., Sison, E.A., Magoon, D., Qi, J., Blatt, K., Wunderlich, M., et al. RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia. Nature 478 (2011), 524–528.
-
(2011)
Nature
, vol.478
, pp. 524-528
-
-
Zuber, J.1
Shi, J.2
Wang, E.3
Rappaport, A.R.4
Herrmann, H.5
Sison, E.A.6
Magoon, D.7
Qi, J.8
Blatt, K.9
Wunderlich, M.10
|