-
1
-
-
44749092645
-
Lis1/dynactin regulates metaphase spindle orientation in drosophila neuroblasts
-
Siller, K.H. & Doe, C.Q. Lis1/dynactin regulates metaphase spindle orientation in Drosophila neuroblasts. Dev. Biol. 319, 1-9 (2008
-
(2008)
Dev. Biol
, vol.319
, pp. 1-9
-
-
Siller, K.H.1
Doe, C.Q.2
-
2
-
-
38849091345
-
Neuroepithelial stem cell proliferation requires LIS1 for precise spindle orientation and symmetric division
-
Yingling, J. et al. Neuroepithelial stem cell proliferation requires LIS1 for precise spindle orientation and symmetric division. Cell 132, 474-486 (2008
-
(2008)
Cell
, vol.132
, pp. 474-486
-
-
Yingling, J.1
-
3
-
-
0021418563
-
Disparate differentiation in mouse hemopoietic colonies derived from paired progenitors
-
Suda, T., Suda, J. & Ogawa, M. Disparate differentiation in mouse hemopoietic colonies derived from paired progenitors. Proc. Natl. Acad. Sci. USA 81, 2520-2524 (1984
-
(1984)
Proc. Natl. Acad. Sci. USA
, vol.81
, pp. 2520-2524
-
-
Suda, T.1
Suda, J.2
Ogawa, M.3
-
4
-
-
84858696013
-
Asymmetric segregation and self-renewal of hematopoietic stem and progenitor cells with endocytic ap2a2
-
Ting, S.B et al. Asymmetric segregation and self-renewal of hematopoietic stem and progenitor cells with endocytic Ap2a2. Blood 119, 2510-2522 (2012
-
(2012)
Blood
, vol.119
, pp. 2510-2522
-
-
Ting, S.B.1
-
5
-
-
35848948403
-
Imaging hematopoietic precursor division in real time
-
Wu, M. et al. Imaging hematopoietic precursor division in real time. Cell Stem Cell 1, 541-554 (2007
-
(2007)
Cell Stem Cell
, vol.1
, pp. 541-554
-
-
Wu, M.1
-
6
-
-
77956449328
-
An rnai screen identifies msi2 and prox1 as having opposite roles in the regulation of hematopoietic stem cell activity
-
Hope, K.J. et al. An RNAi screen identifies Msi2 and Prox1 as having opposite roles in the regulation of hematopoietic stem cell activity. Cell Stem Cell 7, 101-113 (2010
-
(2010)
Cell Stem Cell
, vol.7
, pp. 101-113
-
-
Hope, K.J.1
-
7
-
-
33845969499
-
Regulation of reactive oxygen species by Atm is essential for proper response to DNA double-strand breaks in lymphocytes
-
Ito, K. et al. Regulation of reactive oxygen species by Atm is essential for proper response to DNA double-strand breaks in lymphocytes. J. Immunol. 178, 103-110 (2007
-
(2007)
J. Immunol
, vol.178
, pp. 103-110
-
-
Ito, K.1
-
8
-
-
77955431522
-
Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia
-
Kharas, M.G. et al. Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia. Nat. Med. 16, 903-908 (2010
-
(2010)
Nat. Med
, vol.16
, pp. 903-908
-
-
Kharas, M.G.1
-
9
-
-
79960668304
-
Musashi 2 is a regulator of the HSC compartment identified by a retroviral insertion screen and knockout mice
-
de Andrés-Aguayo, L. et al. Musashi 2 is a regulator of the HSC compartment identified by a retroviral insertion screen and knockout mice. Blood 118, 554-564 (2011
-
(2011)
Blood
, vol.118
, pp. 554-564
-
-
De Andrés-Aguayo, L.1
-
10
-
-
77955512823
-
Regulation of myeloid leukaemia by the cell-fate determinant Musashi
-
Ito, T. et al. Regulation of myeloid leukaemia by the cell-fate determinant Musashi. Nature 466, 765-768 (2010
-
(2010)
Nature
, vol.466
, pp. 765-768
-
-
Ito, T.1
-
11
-
-
0031848149
-
Graded reduction of Pafah1b1 (Lis1) activity results in neuronal migration defects and early embryonic lethality
-
Hirotsune, S. et al. Graded reduction of Pafah1b1 (Lis1) activity results in neuronal migration defects and early embryonic lethality. Nat. Genet. 19, 333-339 (1998
-
(1998)
Nat. Genet
, vol.19
, pp. 333-339
-
-
Hirotsune, S.1
-
12
-
-
0037332003
-
Transgenic mice with hematopoietic and lymphoid specific expression of Cre
-
de Boer, J. et al. Transgenic mice with hematopoietic and lymphoid specific expression of Cre. Eur. J. Immunol. 33, 314-325 (2003
-
(2003)
Eur. J. Immunol
, vol.33
, pp. 314-325
-
-
De Boer, J.1
-
13
-
-
1642634598
-
Regulatory elements of the vav gene drive transgene expression in hematopoietic stem cells from adult mice
-
Almarza, E. et al. Regulatory elements of the vav gene drive transgene expression in hematopoietic stem cells from adult mice. Exp. Hematol. 32, 360-364 (2004
-
(2004)
Exp. Hematol
, vol.32
, pp. 360-364
-
-
Almarza, E.1
-
14
-
-
0033567901
-
Promoter elements of vav drive transgene expression in vivo throughout the hematopoietic compartment
-
Ogilvy, S. et al. Promoter elements of vav drive transgene expression in vivo throughout the hematopoietic compartment. Blood 94, 1855-1863 (1999
-
(1999)
Blood
, vol.94
, pp. 1855-1863
-
-
Ogilvy, S.1
-
15
-
-
33846899456
-
Restoration of p53 function leads to tumour regression in vivo
-
Ventura, A. et al. Restoration of p53 function leads to tumour regression in vivo. Nature 445, 661-665 (2007
-
(2007)
Nature
, vol.445
, pp. 661-665
-
-
Ventura, A.1
-
16
-
-
41449118521
-
Module map of stem cell genes guides creation of epithelial cancer stem cells
-
Wong, D.J. et al. Module map of stem cell genes guides creation of epithelial cancer stem cells. Cell Stem Cell 2, 333-344 (2008
-
(2008)
Cell Stem Cell
, vol.2
, pp. 333-344
-
-
Wong, D.J.1
-
17
-
-
8844250116
-
Molecular signatures of proliferation and quiescence in hematopoietic stem cells
-
Venezia, T.A. et al. Molecular signatures of proliferation and quiescence in hematopoietic stem cells. PLoS Biol. 2, e301 (2004
-
(2004)
PLoS Biol
, vol.2
-
-
Venezia, T.A.1
-
18
-
-
80052468964
-
Stem cell gene expression programs influence clinical outcome in human leukemia
-
Eppert, K. et al. Stem cell gene expression programs influence clinical outcome in human leukemia. Nat. Med. 17, 1086-1093 (2011
-
(2011)
Nat. Med
, vol.17
, pp. 1086-1093
-
-
Eppert, K.1
-
19
-
-
33947596005
-
Integrin-mediated adhesion orients the spindle parallel to the substratum in an EB1-And myosin X-dependent manner
-
Toyoshima, F. & Nishida, E. Integrin-mediated adhesion orients the spindle parallel to the substratum in an EB1-And myosin X-dependent manner. EMBO J. 26, 1487-1498 (2007
-
(2007)
EMBO J.
, vol.26
, pp. 1487-1498
-
-
Toyoshima, F.1
Nishida, E.2
-
20
-
-
0032568321
-
Histone-GFP fusion protein enables sensitive analysis of chromosome dynamics in living mammalian cells
-
Kanda, T., Sullivan, K.F. & Wahl, G.M. Histone-GFP fusion protein enables sensitive analysis of chromosome dynamics in living mammalian cells. Curr. Biol. 8, 377-385 (1998
-
(1998)
Curr. Biol
, vol.8
, pp. 377-385
-
-
Kanda, T.1
Sullivan, K.F.2
Wahl, G.M.3
-
21
-
-
60749083502
-
A method for prolonged imaging of motile lymphocytes
-
Day, D. et al. A method for prolonged imaging of motile lymphocytes. Immunol. Cell Biol. 87, 154-158 (2009
-
(2009)
Immunol. Cell Biol
, vol.87
, pp. 154-158
-
-
Day, D.1
-
22
-
-
5144222593
-
Mitotic spindle regulation by Nde1 controls cerebral cortical size
-
Feng, Y. & Walsh, C.A. Mitotic spindle regulation by Nde1 controls cerebral cortical size. Neuron 44, 279-293 (2004
-
(2004)
Neuron
, vol.44
, pp. 279-293
-
-
Feng, Y.1
Walsh, C.A.2
-
23
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
Reya, T., Morrison, S.J., Clarke, M.F. & Weissman, I.L. Stem cells, cancer, and cancer stem cells. Nature 414, 105-111 (2001
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
24
-
-
0037188538
-
A murine model of CML blast crisis induced by cooperation between BCR/ABL and NUP98/HOXA9
-
Dash, A.B. et al. A murine model of CML blast crisis induced by cooperation between BCR/ABL and NUP98/HOXA9. Proc. Natl. Acad. Sci. USA 99, 7622-7627 (2002
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 7622-7627
-
-
Dash, A.B.1
-
25
-
-
0036892511
-
Oncogenic interaction between BCR-ABL and NUP98-HOXA9 demonstrated by the use of an in vitro purging culture system
-
Mayotte, N., Roy, D.C., Yao, J., Kroon, E. & Sauvageau, G. Oncogenic interaction between BCR-ABL and NUP98-HOXA9 demonstrated by the use of an in vitro purging culture system. Blood 100, 4177-4184 (2002
-
(2002)
Blood
, vol.100
, pp. 4177-4184
-
-
Mayotte, N.1
Roy, D.C.2
Yao, J.3
Kroon, E.4
Sauvageau, G.5
-
26
-
-
34948839961
-
Leukemia stem cells in a genetically defined murine model of blast-crisis CML
-
Neering, S.J. et al. Leukemia stem cells in a genetically defined murine model of blast-crisis CML. Blood 110, 2578-2585 (2007
-
(2007)
Blood
, vol.110
, pp. 2578-2585
-
-
Neering, S.J.1
-
27
-
-
64349109459
-
Mouse models of human AML accurately predict chemotherapy response
-
Zuber, J. et al. Mouse models of human AML accurately predict chemotherapy response. Genes Dev. 23, 877-889 (2009
-
(2009)
Genes Dev
, vol.23
, pp. 877-889
-
-
Zuber, J.1
-
28
-
-
0028022916
-
An early haematopoietic defect in mice lacking the transcription factor GATA-2
-
Tsai, F.Y et al. An early haematopoietic defect in mice lacking the transcription factor GATA-2. Nature 371, 221-226 (1994
-
(1994)
Nature
, vol.371
, pp. 221-226
-
-
Tsai, F.Y.1
-
29
-
-
0029918597
-
Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis
-
Wang, Q. et al. Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis. Proc. Natl. Acad. Sci. USA 93, 3444-3449 (1996
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 3444-3449
-
-
Wang, Q.1
-
30
-
-
0030061554
-
AML1 the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis
-
Okuda, T., van Deursen, J., Hiebert, S.W., Grosveld, G. & Downing, J.R. AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis. Cell 84, 321-330 (1996
-
(1996)
Cell
, vol.84
, pp. 321-330
-
-
Okuda, T.1
Van Deursen, J.2
Hiebert, S.W.3
Grosveld, G.4
Downing, J.R.5
-
31
-
-
0030581174
-
The T cell leukemia oncoprotein SCL/tal-1 is essential for development of all hematopoietic lineages
-
Porcher, C. et al. The T cell leukemia oncoprotein SCL/tal-1 is essential for development of all hematopoietic lineages. Cell 86, 47-57 (1996
-
(1996)
Cell
, vol.86
, pp. 47-57
-
-
Porcher, C.1
-
32
-
-
78649874959
-
Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells
-
Gan, B. et al. Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells. Nature 468, 701-704 (2010
-
(2010)
Nature
, vol.468
, pp. 701-704
-
-
Gan, B.1
-
33
-
-
78649811793
-
Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells
-
Nakada, D., Saunders, T.L. & Morrison, S.J. Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells. Nature 468, 653-658 (2010
-
(2010)
Nature
, vol.468
, pp. 653-658
-
-
Nakada, D.1
Saunders, T.L.2
Morrison, S.J.3
-
34
-
-
34250844968
-
The Drosophila Lkb1 kinase is required for spindle formation and asymmetric neuroblast division
-
Bonaccorsi, S. et al. The Drosophila Lkb1 kinase is required for spindle formation and asymmetric neuroblast division. Development 134, 2183-2193 (2007
-
(2007)
Development
, vol.134
, pp. 2183-2193
-
-
Bonaccorsi, S.1
-
35
-
-
2542500611
-
The biology of CML blast crisis
-
Calabretta, B. & Perrotti, D. The biology of CML blast crisis. Blood 103, 4010-4022 (2004
-
(2004)
Blood
, vol.103
, pp. 4010-4022
-
-
Calabretta, B.1
Perrotti, D.2
-
36
-
-
34648821257
-
Molecular heterogeneity of breast carcinomas and the cancer stem cell hypothesis
-
Stingl, J. & Caldas, C. Molecular heterogeneity of breast carcinomas and the cancer stem cell hypothesis. Nat. Rev. Cancer 7, 791-799 (2007
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 791-799
-
-
Stingl, J.1
Caldas, C.2
-
37
-
-
0034987702
-
Malignant glioma: Genetics and biology of a grave matter
-
Maher, E.A. et al. Malignant glioma: Genetics and biology of a grave matter. Genes Dev. 15, 1311-1333 (2001
-
(2001)
Genes Dev
, vol.15
, pp. 1311-1333
-
-
Maher, E.A.1
-
38
-
-
7244250027
-
Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis
-
Pece, S. et al. Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis. J. Cell Biol. 167, 215-221 (2004
-
(2004)
J. Cell Biol
, vol.167
, pp. 215-221
-
-
Pece, S.1
-
39
-
-
33745485289
-
The brain tumor gene negatively regulates neural progenitor cell proliferation in the larval central brain of drosophila
-
Bello, B., Reichert, H. & Hirth, F. The brain tumor gene negatively regulates neural progenitor cell proliferation in the larval central brain of Drosophila. Development 133, 2639-2648 (2006
-
(2006)
Development
, vol.133
, pp. 2639-2648
-
-
Bello, B.1
Reichert, H.2
Hirth, F.3
-
40
-
-
33646027006
-
Asymmetric segregation of the tumor suppressor Brat regulates self-renewal in Drosophila neural stem cells
-
Betschinger, J., Mechtler, K. & Knoblich, J.A. Asymmetric segregation of the tumor suppressor Brat regulates self-renewal in Drosophila neural stem cells. Cell 124, 1241-1253 (2006
-
(2006)
Cell
, vol.124
, pp. 1241-1253
-
-
Betschinger, J.1
Mechtler, K.2
Knoblich, J.A.3
-
41
-
-
27144555447
-
Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster
-
Caussinus, E. & Gonzalez, C. Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster. Nat. Genet. 37, 1125-1129 (2005
-
(2005)
Nat. Genet
, vol.37
, pp. 1125-1129
-
-
Caussinus, E.1
Gonzalez, C.2
-
42
-
-
33845702193
-
Drosophila Aurora-A kinase inhibits neuroblast self-renewal by regulating aPKC/Numb cortical polarity and spindle orientation
-
Lee, C.Y. et al. Drosophila Aurora-A kinase inhibits neuroblast self-renewal by regulating aPKC/Numb cortical polarity and spindle orientation. Genes Dev. 20, 3464-3474 (2006
-
(2006)
Genes Dev
, vol.20
, pp. 3464-3474
-
-
Lee, C.Y.1
-
43
-
-
33645525794
-
Brat is a Miranda cargo protein that promotes neuronal differentiation and inhibits neuroblast self-renewal
-
Lee, C.Y., Wilkinson, B.D., Siegrist, S.E., Wharton, R.P. & Doe, C.Q. Brat is a Miranda cargo protein that promotes neuronal differentiation and inhibits neuroblast self-renewal. Dev. Cell 10, 441-449 (2006
-
(2006)
Dev. Cell
, vol.10
, pp. 441-449
-
-
Lee, C.Y.1
Wilkinson, B.D.2
Siegrist, S.E.3
Wharton, R.P.4
Doe, C.Q.5
-
44
-
-
33845704687
-
Aurora-A acts as a tumor suppressor and regulates self-renewal of Drosophila neuroblasts
-
Wang, H. et al. Aurora-A acts as a tumor suppressor and regulates self-renewal of Drosophila neuroblasts. Genes Dev. 20, 3453-3463 (2006
-
(2006)
Genes Dev
, vol.20
, pp. 3453-3463
-
-
Wang, H.1
-
45
-
-
48449101742
-
Medulloblastoma can be initiated by deletion of Patched in lineage-restricted progenitors or stem cells
-
Yang, Z.J. et al. Medulloblastoma can be initiated by deletion of Patched in lineage-restricted progenitors or stem cells. Cancer Cell 14, 135-145 (2008
-
(2008)
Cancer Cell
, vol.14
, pp. 135-145
-
-
Yang, Z.J.1
-
46
-
-
0034677173
-
The role of apoptosis in the regulation of hematopoietic stem cells: Overexpression of Bcl-2 increases both their number and repopulation potential
-
Domen, J., Cheshier, S.H. & Weissman, I.L. The role of apoptosis in the regulation of hematopoietic stem cells: Overexpression of Bcl-2 increases both their number and repopulation potential. J. Exp. Med. 191, 253-264 (2000
-
(2000)
J. Exp. Med
, vol.191
, pp. 253-264
-
-
Domen, J.1
Cheshier, S.H.2
Weissman, I.L.3
-
47
-
-
0037422583
-
Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5
-
Qin, X.F., An, D.S., Chen, I.S. & Baltimore, D. Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5. Proc. Natl. Acad. Sci. USA 100, 183-188 (2003
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 183-188
-
-
Qin, X.F.1
An, D.S.2
Chen, I.S.3
Baltimore, D.4
-
48
-
-
4444326468
-
Microarray truths and consequences
-
Sásik, R., Woelk, C.H. & Corbeil, J. Microarray truths and consequences. J. Mol. Endocrinol. 33, 1-9 (2004
-
(2004)
J. Mol. Endocrinol
, vol.33
, pp. 1-9
-
-
Sásik, R.1
Woelk, C.H.2
Corbeil, J.3
-
49
-
-
0001677717
-
Controlling the false discovery rate: A practical and powerful approach to multiple testing
-
Benjamini, Y. & Hochberg, Y. Controlling the false discovery rate: A practical and powerful approach to multiple testing. J. R. Stat. Soc. B 57, 289-300 (1995
-
(1995)
J. R. Stat. Soc
, vol.B57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
50
-
-
0035942271
-
Significance analysis of microarrays applied to the ionizing radiation response
-
Tusher, V.G., Tibshirani, R. & Chu, G. Significance analysis of microarrays applied to the ionizing radiation response. Proc. Natl. Acad. Sci. USA 98, 5116-5121 (2001
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 5116-5121
-
-
Tusher, V.G.1
Tibshirani, R.2
Chu, G.3
-
51
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
-
Subramanian, A. et al. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles. Proc. Natl. Acad. Sci. USA 102, 15545-15550 (2005
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 15545-15550
-
-
Subramanian, A.1
-
52
-
-
0003780756
-
-
Wiley Series in Probability and Statistics) (John Wiley & Sons, New York
-
Arnold, B.C., Balakrishnan, N. & Nagaraja, H.N. A First Course in Order Statistics (Wiley Series in Probability and Statistics) (John Wiley & Sons, New York, 1992
-
(1992)
A First Course In Order Statistics
-
-
Arnold, B.C.1
Balakrishnan, N.2
Nagaraja, H.N.3
-
53
-
-
57449103508
-
An 86-probe-set gene-expression signature predicts survival in cytogenetically normal acute myeloid leukemia
-
Metzeler, K.H. et al. An 86-probe-set gene-expression signature predicts survival in cytogenetically normal acute myeloid leukemia. Blood 112, 4193-4201 (2008
-
(2008)
Blood
, vol.112
, pp. 4193-4201
-
-
Metzeler, K.H.1
-
54
-
-
58949102947
-
Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells
-
Somervaille, T.C. et al. Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells. Cell Stem Cell 4, 129-140 (2009
-
(2009)
Cell Stem Cell
, vol.4
, pp. 129-140
-
-
Somervaille, T.C.1
-
55
-
-
0041940309
-
Identification of a gene expression signature associated with pediatric AML prognosis
-
Yagi, T. et al. Identification of a gene expression signature associated with pediatric AML prognosis. Blood 102, 1849-1856 (2003.
-
(2003)
Blood
, vol.102
, pp. 1849-1856
-
-
Yagi, T.1
|