An insulin-IAPP hybrid peptide is an endogenous antigen for CD4 T cells in the non-obese diabetic mouse

Journal of Autoimmunity

Volumn 78, Issue , 2017, Pages 11-18

  Wiles, Timothy A ^a   Delong, Thomas ^a   Baker, Rocky L ^a   Bradley, Brenda ^a   Barbour, Gene ^a   Powell, Roger L ^a   Reisdorph, Nichole ^a   Haskins, Kathryn ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

Autoimmune type 1 diabetes; Hybrid insulin peptides (HIPs); Non obese diabetic (NOD) mouse; Peptide fusion; Tetramer

Indexed keywords

AMYLIN; EPITOPE; HYBRID PROTEIN; INSULIN; TETRAMER; AUTOANTIGEN; C PEPTIDE;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGENICITY; ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; MASS SPECTROMETRY; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; PANCREAS; PANCREAS ISLET BETA CELL; PEPTIDE ANALYSIS; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SECRETORY GRANULE; SPLEEN; SPLEEN CELL; ANIMAL; BAGG ALBINO MOUSE; CELL CULTURE; CHEMISTRY; IMMUNOLOGY; KNOCKOUT MOUSE; LYMPHOCYTE ACTIVATION; METABOLISM;

AMINO ACID SEQUENCE; ANIMALS; AUTOANTIGENS; C-PEPTIDE; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; EPITOPES, T-LYMPHOCYTE; INSULIN; ISLET AMYLOID POLYPEPTIDE; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, INBRED NOD; MICE, KNOCKOUT;

EID: 85005978093     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2016.10.007     Document Type: Article

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