Sesamin inhibits IL-1β-stimulated inflammatory response in human osteoarthritis chondrocytes by activating Nrf2 signaling pathway

Oncotarget

Volumn 7, Issue 50, 2016, Pages 83720-83726

  Kong, Pengyu ^a   Chen, Guanghua ^a   Jiang, Anlong ^a   Wang, Yufu ^a   Song, Chengchao ^a   Zhuang, Jinpeng ^a   Xi, Chunyang ^a   Wang, Guangxi ^a   Ji, Ye ^a   Yan, Jinglong ^a  

^a THE SECOND AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

IL 1 ; NF B; Nrf2; Osteoarthritis chondrocyte; Sesamin

Indexed keywords

COLLAGENASE 3; HEME OXYGENASE 1; I KAPPA B ALPHA; INTERSTITIAL COLLAGENASE; NITRIC OXIDE; PROSTAGLANDIN E2; SESAMIN; SMALL INTERFERING RNA; STROMELYSIN; TRANSCRIPTION FACTOR NRF2; TRANSCRIPTION FACTOR RELA; 1,3 DIOXOLANE DERIVATIVE; ANTIINFLAMMATORY AGENT; HMOX1 PROTEIN, HUMAN; I KAPPA B KINASE ALPHA; IL1B PROTEIN, HUMAN; INTERLEUKIN 1BETA; LIGNAN; MATRIX METALLOPROTEINASE; NFE2L2 PROTEIN, HUMAN; NFKBIA PROTEIN, HUMAN; RELA PROTEIN, HUMAN;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CARTILAGE CELL; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; HUMAN; HUMAN CELL; OSTEOARTHRITIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION; CELL CULTURE; CELL SURVIVAL; CHONDROCYTE; DOSE RESPONSE; DRUG EFFECTS; GENETIC TRANSFECTION; GENETICS; IMMUNOLOGY; KNEE OSTEOARTHRITIS; METABOLISM; MIDDLE AGED; PHOSPHORYLATION; RNA INTERFERENCE;

ANTI-INFLAMMATORY AGENTS; CELL SURVIVAL; CELLS, CULTURED; CHONDROCYTES; DINOPROSTONE; DIOXOLES; DOSE-RESPONSE RELATIONSHIP, DRUG; HEME OXYGENASE-1; HUMANS; INTERLEUKIN-1BETA; LIGNANS; MATRIX METALLOPROTEINASES, SECRETED; MIDDLE AGED; NF-E2-RELATED FACTOR 2; NF-KAPPAB INHIBITOR ALPHA; NITRIC OXIDE; OSTEOARTHRITIS, KNEE; PHOSPHORYLATION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELA; TRANSFECTION;

EID: 85004140733     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.13360     Document Type: Article

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