Biased agonism of three different cannabinoid receptor agonists in mouse brain cortex

Frontiers in Pharmacology

Volumn 7, Issue NOV, 2016, Pages

  Diez Alarcia, Rebeca ^a,b   Ibarra Lecue, Inés ^a   Lopez Cardona, Ángela P ^c,d   Meana, Javier ^a,b   Gutierrez Adán, Alfonso ^c   Callado, Luis F ^a,b   Agirregoitia, Ekaitz ^a   Urigüen, Leyre ^a,b  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^b CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE SALUD MENTAL CIBERSAM   (Spain)

^c Institute Nacional de Investigatión Agraria Y Alimentaría   (Spain)

^d UNIVERSIDAD DE ANTIOQUIA   (Colombia)

Author keywords

Brain; CB1 receptor; CB2 receptor; Functional selectivity; G proteins; Scintillation proximity assay (SPA)

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; ANANDAMIDE; ARACHIDONYL 2 CHLOROETHYLAMIDE; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; CANNABINOID RECEPTOR AGONIST; DRONABINOL; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT 11; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT 12; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT 13; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT O; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT Q; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT S; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT Z; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN 1; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN 2; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN 3; O 2050; UNCLASSIFIED DRUG;

ADULT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN MEMBRANE; CONTROLLED STUDY; KNOCKOUT MOUSE; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION;

EID: 85003561673     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2016.00415     Document Type: Article

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