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Volumn 211, Issue 5, 2014, Pages 943-959

RGMb is a novel binding partner for PD-l2 and its engagement with PD-l2 promotes respiratory tolerance

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; MESSENGER RNA; PROGRAMMED DEATH 1 LIGAND 2; REPULSIVE GUIDANCE MOLECULE B; UNCLASSIFIED DRUG;

EID: 84899758346     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20130790     Document Type: Article
Times cited : (261)

References (54)
  • 2
    • 84876369641 scopus 로고    scopus 로고
    • TIM-4, expressed by medullary macrophages, regulates respiratory tolerance by mediating phagocytosis of antigen-specific T cells
    • Albacker, L.A., S. Yu, D. Bedoret, W.L. Lee, S.E. Umetsu, S. Monahan, G.J. Freeman, D.T. Umetsu, and R.H. Dekruyff. 2013. TIM-4, expressed by medullary macrophages, regulates respiratory tolerance by mediating phagocytosis of antigen-specific T cells. Mucosal Immunol. 6:580-590. 10.1038/mi.2012.100.
    • (2013) Mucosal Immunol , vol.6 , pp. 580-590
    • Albacker, L.A.1    Yu, S.2    Bedoret, D.3    Lee, W.L.4    Umetsu, S.E.5    Monahan, S.6    Freeman, G.J.7    Umetsu, D.T.8    Dekruyff, R.H.9
  • 6
    • 84857670611 scopus 로고    scopus 로고
    • The role of alveolar epithelial cells in initiating and shaping pulmonary immune responses: communication between innate and adaptive immune systems
    • Chuquimia, O.D., D.H. Petursdottir, M.J. Rahman, K. Hartl, M. Singh, and C. Fernández. 2012. The role of alveolar epithelial cells in initiating and shaping pulmonary immune responses: communication between innate and adaptive immune systems. PLoS ONE. 7:e32125. http://dx.doi.org/10.1371/journal.pone.0032125
    • (2012) PLoS ONE , vol.7 , pp. 5
    • Chuquimia, O.D.1    Petursdottir, D.H.2    Rahman, M.J.3    Hartl, K.4    Singh, M.5    Fernández, C.6
  • 7
    • 34447500066 scopus 로고    scopus 로고
    • Neogenin-RGMa signaling at the growth cone is bone morphogenetic proteinindependent and involves RhoA, ROCK, and PKC
    • Conrad, S., H. Genth, F. Hofmann, I. Just, and T. Skutella. 2007. Neogenin-RGMa signaling at the growth cone is bone morphogenetic proteinindependent and involves RhoA, ROCK, and PKC. J. Biol. Chem. 282:16423-16433. http://dx.doi.org/10.1074/jbc. M610901200
    • (2007) J. Biol. Chem , vol.282 , pp. 5
    • Conrad, S.1    Genth, H.2    Hofmann, F.3    Just, I.4    Skutella, T.5
  • 9
    • 70849085415 scopus 로고    scopus 로고
    • The RGM/DRAGON family of BMP co-receptors
    • Corradini, E., J.L. Babitt, and H.Y. Lin. 2009. The RGM/DRAGON family of BMP co-receptors. Cytokine Growth Factor Rev. 20:389-398. http://dx.doi.org/10.1016/j.cytogfr.2009.10.008
    • (2009) Cytokine Growth Factor Rev , vol.20 , pp. 389-398
    • Corradini, E.1    Babitt, J.L.2    Lin, H.Y.3
  • 10
    • 0024444165 scopus 로고
    • B7, a new member of the Ig superfamily with unique expression on activated and neoplastic B cells
    • Freeman, G.J., A.S. Freedman, J.M. Segil, G. Lee, J.F. Whitman, and L.M. Nadler. 1989. B7, a new member of the Ig superfamily with unique expression on activated and neoplastic B cells. J. Immunol. 143: 2714-2722.
    • (1989) J. Immunol. , vol.143 , pp. 2714-2722
    • Freeman, G.J.1    Freedman, A.S.2    Segil, J.M.3    Lee, G.4    Whitman, J.F.5    Nadler, L.M.6
  • 11
    • 34548448091 scopus 로고    scopus 로고
    • Distinctive gene expression signatures in rheumatoid arthritis synovial tissue fibroblast cells: correlates with disease activity
    • Galligan, C.L., E. Baig, V. Bykerk, E.C. Keystone, and E.N. Fish. 2007. Distinctive gene expression signatures in rheumatoid arthritis synovial tissue fibroblast cells: correlates with disease activity. Genes Immun. 8:480-491. http://dx.doi.org/10.1038/sj.gene.6364400
    • (2007) Genes Immun , vol.8 , pp. 5
    • Galligan, C.L.1    Baig, E.2    Bykerk, V.3    Keystone, E.C.4    Fish, E.N.5
  • 12
    • 54349108686 scopus 로고    scopus 로고
    • Division of labor between dendritic cell subsets of the lung
    • GeurtsvanKessel, C.H., and B.N. Lambrecht. 2008. Division of labor between dendritic cell subsets of the lung. Mucosal Immunol. 1:442-450. http://dx.doi.org/10.1038/mi.2008.39
    • (2008) Mucosal Immunol , vol.1 , pp. 5
    • GeurtsvanKessel, C.H.1    Lambrecht, B.N.2
  • 13
    • 0037099676 scopus 로고    scopus 로고
    • The developmentally regulated expression of Twisted gastrulation reveals a role for bone morphogenetic proteins in the control of T cell development
    • Graf, D., S. Nethisinghe, D.B. Palmer, A.G. Fisher, and M. Merkenschlager. 2002. The developmentally regulated expression of Twisted gastrulation reveals a role for bone morphogenetic proteins in the control of T cell development. J. Exp. Med. 196:163-171. http://dx.doi.org/10.1084/jem.20020276
    • (2002) J. Exp. Med. , vol.196 , pp. 5
    • Graf, D.1    Nethisinghe, S.2    Palmer, D.B.3    Fisher, A.G.4    Merkenschlager, M.5
  • 17
    • 32644451168 scopus 로고    scopus 로고
    • Engagement of CD83 ligand induces prolonged expansion of CD8+ T cells and preferential enrichment for antigen specificity
    • Hirano, N., M.O. Butler, Z. Xia, S. Ansén, M.S. von Bergwelt-Baildon, D. Neuberg, G.J. Freeman, and L.M. Nadler. 2006. Engagement of CD83 ligand induces prolonged expansion of CD8+ T cells and preferential enrichment for antigen specificity. Blood. 107:1528-1536. http://dx.doi.org/10.1182/blood-2005-05-2073
    • (2006) Blood , vol.107 , pp. 5
    • Hirano, N.1    Butler, M.O.2    Xia, Z.3    Ansén, S.4    von Bergwelt-Baildon, M.S.5    Neuberg, D.6    Freeman, G.J.7    Nadler, L.M.8
  • 18
    • 4143085893 scopus 로고    scopus 로고
    • The role of dendritic cells in asthma
    • Holt, P.G., and J.W. Upham. 2004. The role of dendritic cells in asthma. Curr. Opin. Allergy Clin. Immunol. 4:39-44. http://dx.doi.org/10.1097/00130832-200402000-00009
    • (2004) Curr. Opin. Allergy Clin. Immunol , vol.4 , pp. 5
    • Holt, P.G.1    Upham, J.W.2
  • 19
    • 0030068998 scopus 로고    scopus 로고
    • Regulation of house dust mite responses by intranasally administered peptide: transient activation of CD4+ T cells precedes the development of tolerance in vivo
    • Hoyne, G.F., B.A. Askonas, C. Hetzel, W.R. Thomas, and J.R. Lamb. 1996. Regulation of house dust mite responses by intranasally administered peptide: transient activation of CD4+ T cells precedes the development of tolerance in vivo. Int. Immunol. 8:335-342. http://dx.doi.org/10.1093/intimm/8.3.335
    • (1996) Int. Immunol , vol.8 , pp. 5
    • Hoyne, G.F.1    Askonas, B.A.2    Hetzel, C.3    Thomas, W.R.4    Lamb, J.R.5
  • 20
    • 42649125225 scopus 로고    scopus 로고
    • PD-1 and its ligands in tolerance and immunity
    • Keir, M.E., M.J. Butte, G.J. Freeman, and A.H. Sharpe. 2008. PD-1 and its ligands in tolerance and immunity. Annu. Rev. Immunol. 26:677-704. http://dx.doi.org/10.1146/annurev.immunol.26.021607.090331
    • (2008) Annu. Rev. Immunol , vol.26 , pp. 5
    • Keir, M.E.1    Butte, M.J.2    Freeman, G.J.3    Sharpe, A.H.4
  • 22
    • 84857822677 scopus 로고    scopus 로고
    • The axonal guidance receptor neogenin promotes acute inflammation
    • König, K., D. Gatidou, T. Granja, J. Meier, P. Rosenberger, and V. Mirakaj. 2012. The axonal guidance receptor neogenin promotes acute inflammation. PLoS ONE. 7:e32145. http://dx.doi.org/10.1371/journal.pone.0032145
    • (2012) PLoS ONE , vol.7 , pp. 5
    • König, K.1    Gatidou, D.2    Granja, T.3    Meier, J.4    Rosenberger, P.5    Mirakaj, V.6
  • 23
    • 80355145827 scopus 로고    scopus 로고
    • Isolation of mouse respiratory epithelial cells and exposure to experimental cigarette smoke at air liquid interface
    • Lam, H.C., A.M. Choi, and S.W. Ryter. 2011. Isolation of mouse respiratory epithelial cells and exposure to experimental cigarette smoke at air liquid interface. J. Vis. Exp. 48:2513.
    • (2011) J. Vis. Exp. , vol.48 , pp. 2513
    • Lam, H.C.1    Choi, A.M.2    Ryter, S.W.3
  • 25
    • 82455167972 scopus 로고    scopus 로고
    • PD-L2 is predominantly expressed by Th2 cells
    • Lesterhuis, W.J., H. Steer, and R.A. Lake. 2011. PD-L2 is predominantly expressed by Th2 cells. Mol. Immunol. 49:1-3. http://dx.doi.org/10.1016/j.molimm.2011.09.014
    • (2011) Mol. Immunol , vol.49 , pp. 5
    • Lesterhuis, W.J.1    Steer, H.2    Lake, R.A.3
  • 26
    • 84862973218 scopus 로고    scopus 로고
    • Repulsive guidance molecules, novel bone morphogenetic protein co-receptors, are key regulators of the growth and aggressiveness of prostate cancer cells
    • Li, J., L. Ye, H.G. Kynaston, and W.G. Jiang. 2012a. Repulsive guidance molecules, novel bone morphogenetic protein co-receptors, are key regulators of the growth and aggressiveness of prostate cancer cells. Int. J. Oncol. 40:544-550.
    • (2012) Int. J. Oncol. , vol.40 , pp. 544-550
    • Li, J.1    Ye, L.2    Kynaston, H.G.3    Jiang, W.G.4
  • 27
    • 84861078343 scopus 로고    scopus 로고
    • Repulsive guidance molecule B (RGMB) plays negative roles in breast cancer by coordinating BMP signaling
    • Li, J., L. Ye, A.J. Sanders, and W.G. Jiang. 2012b. Repulsive guidance molecule B (RGMB) plays negative roles in breast cancer by coordinating BMP signaling. J. Cell. Biochem. 113:2523-2531. http://dx.doi.org/10.1002/jcb.24128
    • (2012) J. Cell. Biochem. , vol.113 , pp. 2523-2531
    • Li, J.1    Ye, L.2    Sanders, A.J.3    Jiang, W.G.4
  • 29
    • 84887069887 scopus 로고    scopus 로고
    • Dragon (RGMb) inhibits E-Cadherin expression and induces apoptosis in renal tubular epithelial cells
    • Liu, W., X. Li, Y. Zhao, X.M. Meng, C. Wan, B. Yang, H.Y. Lan, H.Y. Lin, and Y. Xia. 2013. Dragon (RGMb) inhibits E-Cadherin expression and induces apoptosis in renal tubular epithelial cells. J. Biol. Chem. 288:31528-31539. http://dx.doi.org/10.1074/jbc. M113.517573
    • (2013) J. Biol. Chem , vol.288 , pp. 5
    • Liu, W.1    Li, X.2    Zhao, Y.3    Meng, X.M.4    Wan, C.5    Yang, B.6    Lan, H.Y.7    Lin, H.Y.8    Xia, Y.9
  • 30
    • 74249121391 scopus 로고    scopus 로고
    • Synergistic effect of TGF-beta superfamily members on the induction of Foxp3+ Treg
    • Lu, L., J. Ma, X. Wang, J. Wang, F. Zhang, J. Yu, G. He, B. Xu, D.D. Brand, D.A. Horwitz, et al. 2010. Synergistic effect of TGF-beta superfamily members on the induction of Foxp3+ Treg. Eur. J. Immunol. 40:142-152. http://dx.doi.org/10.1002/eji.200939618
    • (2010) Eur. J. Immunol , vol.40 , pp. 5
    • Lu, L.1    Ma, J.2    Wang, X.3    Wang, J.4    Zhang, F.5    Yu, J.6    He, G.7    Xu, B.8    Brand, D.D.9    Horwitz, D.A.10
  • 31
    • 80051940011 scopus 로고    scopus 로고
    • PD-L2 is expressed on activated human T cells and regulates their function
    • Messal, N., N.E. Serriari, S. Pastor, J.A. Nunés, and D. Olive. 2011. PD-L2 is expressed on activated human T cells and regulates their function. Mol. Immunol. 48:2214-2219. http://dx.doi.org/10.1016/j.molimm.2011.06.436
    • (2011) Mol. Immunol , vol.48 , pp. 5
    • Messal, N.1    Serriari, N.E.2    Pastor, S.3    Nunés, J.A.4    Olive, D.5
  • 32
    • 84860904978 scopus 로고    scopus 로고
    • The guidance receptor neogenin promotes pulmonary inflammation during lung injury
    • Mirakaj, V., C. Jennewein, K. König, T. Granja, and P. Rosenberger. 2012. The guidance receptor neogenin promotes pulmonary inflammation during lung injury. FASEB J. 26:1549-1558. http://dx.doi.org/10.1096/fj.11-200063
    • (2012) FASEB J , vol.26 , pp. 5
    • Mirakaj, V.1    Jennewein, C.2    König, K.3    Granja, T.4    Rosenberger, P.5
  • 33
    • 84865416551 scopus 로고    scopus 로고
    • B7-DC-Ig enhances vaccine effect by a novel mechanism dependent on PD-1 expression level on T cell subsets
    • Mkrtichyan, M., Y.G. Najjar, E.C. Raulfs, L. Liu, S. Langerman, G. Guittard, L. Ozbun, and S.N. Khleif. 2012. B7-DC-Ig enhances vaccine effect by a novel mechanism dependent on PD-1 expression level on T cell subsets. J. Immunol. 189:2338-2347. http://dx.doi.org/10.4049/jimmunol.1103085
    • (2012) J. Immunol , vol.189 , pp. 5
    • Mkrtichyan, M.1    Najjar, Y.G.2    Raulfs, E.C.3    Liu, L.4    Langerman, S.5    Guittard, G.6    Ozbun, L.7    Khleif, S.N.8
  • 35
    • 84858766182 scopus 로고    scopus 로고
    • The blockade of immune checkpoints in cancer immunotherapy
    • Pardoll, D.M. 2012. The blockade of immune checkpoints in cancer immunotherapy. Nat. Rev. Cancer. 12:252-264. http://dx.doi.org/10.1038/nrc3239
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 5
    • Pardoll, D.M.1
  • 36
    • 33646559596 scopus 로고    scopus 로고
    • No evidence for dualism in function and receptors: PD-L2/B7-DC is an inhibitory regulator of human T cell activation
    • Pfistershammer, K., C. Klauser, W.F. Pickl, J. Stöckl, J. Leitner, G. Zlabinger, O. Majdic, and P. Steinberger. 2006. No evidence for dualism in function and receptors: PD-L2/B7-DC is an inhibitory regulator of human T cell activation. Eur. J. Immunol. 36:1104-1113. http://dx.doi.org/10.1002/eji.200535344
    • (2006) Eur. J. Immunol , vol.36 , pp. 5
    • Pfistershammer, K.1    Klauser, C.2    Pickl, W.F.3    Stöckl, J.4    Leitner, J.5    Zlabinger, G.6    Majdic, O.7    Steinberger, P.8
  • 37
    • 84856929908 scopus 로고    scopus 로고
    • Antibodies against B7-DC with differential binding properties exert opposite effects
    • Ritprajak, P., M. Hashiguchi, H. Akiba, H. Yagita, K. Okumura, and M. Azuma. 2012. Antibodies against B7-DC with differential binding properties exert opposite effects. Hybridoma (Larchmt). 31:40-47. http://dx.doi.org/10.1089/hyb.2011.0087
    • (2012) Hybridoma (Larchmt) , vol.31 , pp. 5
    • Ritprajak, P.1    Hashiguchi, M.2    Akiba, H.3    Yagita, H.4    Okumura, K.5    Azuma, M.6
  • 38
    • 0035984569 scopus 로고    scopus 로고
    • Activation of bone morphogenetic protein/Smad signaling in bronchial epithelial cells during airway inflammation
    • Rosendahl, A., E. Pardali, M. Speletas, P. Ten Dijke, C.H. Heldin, and P. Sideras. 2002. Activation of bone morphogenetic protein/Smad signaling in bronchial epithelial cells during airway inflammation. Am. J. Respir. Cell Mol. Biol. 27:160-169. http://dx.doi.org/10.1165/ajrcmb.27.2.4779
    • (2002) Am, J. Respir. Cell Mol. Biol , vol.27 , pp. 5
    • Rosendahl, A.1    Pardali, E.2    Speletas, M.3    Ten Dijke, P.4    Heldin, C.H.5    Sideras, P.6
  • 40
    • 70249087694 scopus 로고    scopus 로고
    • Molecular biology, genetics and biochemistry of the repulsive guidance molecule family
    • Severyn, C.J., U. Shinde, and P. Rotwein. 2009. Molecular biology, genetics and biochemistry of the repulsive guidance molecule family. Biochem. J. 422:393-403. http://dx.doi.org/10.1042/BJ20090978
    • (2009) Biochem J , vol.422 , pp. 5
    • Severyn, C.J.1    Shinde, U.2    Rotwein, P.3
  • 42
    • 78651071600 scopus 로고    scopus 로고
    • Role of PD-L1 and PD-L2 in allergic diseases and asthma
    • Singh, A.K., P. Stock, and O. Akbari. 2011. Role of PD-L1 and PD-L2 in allergic diseases and asthma. Allergy. 66:155-162. http://dx.doi.org/10.1111/j.1398-9995.2010.02458.x
    • (2011) Allergy , vol.66 , pp. 5
    • Singh, A.K.1    Stock, P.2    Akbari, O.3
  • 43
    • 78649856609 scopus 로고    scopus 로고
    • Epithelial-dendritic cell interactions in allergic disorders
    • Strickland, D.H., J.W. Upham, and P.G. Holt. 2010. Epithelial-dendritic cell interactions in allergic disorders. Curr. Opin. Immunol. 22:789-794. http://dx.doi.org/10.1016/j.coi.2010.10.019
    • (2010) Curr. Opin. Immunol , vol.22 , pp. 5
    • Strickland, D.H.1    Upham, J.W.2    Holt, P.G.3
  • 44
    • 84884726448 scopus 로고    scopus 로고
    • Repulsive guidance molecules (RGMs) and neogenin in bone morphogenetic protein (BMP) signaling
    • Tian, C., and J. Liu. 2013. Repulsive guidance molecules (RGMs) and neogenin in bone morphogenetic protein (BMP) signaling. Mol. Reprod. Dev. 80:700-717.
    • (2013) Mol. Reprod. Dev. , vol.80 , pp. 700-717
    • Tian, C.1    Liu, J.2
  • 47
    • 0033198184 scopus 로고    scopus 로고
    • Intranasal exposure to protein antigen induces immunological tolerance mediated by functionally disabled CD4+ T cells
    • Tsitoura, D.C., R.H. DeKruyff, J.R. Lamb, and D.T. Umetsu. 1999. Intranasal exposure to protein antigen induces immunological tolerance mediated by functionally disabled CD4+ T cells. J. Immunol. 163:2592-2600.
    • (1999) J. Immunol. , vol.163 , pp. 2592-2600
    • Tsitoura, D.C.1    DeKruyff, R.H.2    Lamb, J.R.3    Umetsu, D.T.4
  • 48
    • 0038185203 scopus 로고    scopus 로고
    • Molecular modeling and functional mapping of B7-H1 and B7-DC uncouple costimulatory function from PD-1 interaction
    • Wang, S., J. Bajorath, D.B. Flies, H. Dong, T. Honjo, and L. Chen. 2003. Molecular modeling and functional mapping of B7-H1 and B7-DC uncouple costimulatory function from PD-1 interaction. J. Exp. Med. 197:1083-1091. http://dx.doi.org/10.1084/jem.20021752
    • (2003) J. Exp. Med , vol.197 , pp. 5
    • Wang, S.1    Bajorath, J.2    Flies, D.B.3    Dong, H.4    Honjo, T.5    Chen, L.6
  • 49
    • 84866928814 scopus 로고    scopus 로고
    • Repulsive guidance molecule (RGM) family proteins exhibit differential binding kinetics for bone morphogenetic proteins (BMPs)
    • Wu, Q., C.C. Sun, H.Y. Lin, and J.L. Babitt. 2012. Repulsive guidance molecule (RGM) family proteins exhibit differential binding kinetics for bone morphogenetic proteins (BMPs). PLoS ONE. 7:e46307. http://dx.doi.org/10.1371/journal.pone.0046307
    • (2012) PLoS ONE , vol.7 , pp. 5
    • Wu, Q.1    Sun, C.C.2    Lin, H.Y.3    Babitt, J.L.4
  • 51
    • 84888114656 scopus 로고    scopus 로고
    • Identification of bone morphogenetic protein 7 (BMP7) as an instructive factor for human epidermal Langerhans cell differentiation
    • Yasmin, N., T. Bauer, M. Modak, K. Wagner, C. Schuster, R. Köffel, M. Seyerl, J. Stöckl, A. Elbe-Bürger, D. Graf, and H. Strobl. 2013. Identification of bone morphogenetic protein 7 (BMP7) as an instructive factor for human epidermal Langerhans cell differentiation. J. Exp. Med. 210:2597-2610. http://dx.doi.org/10.1084/jem.20130275
    • (2013) J. Exp. Med , vol.210 , pp. 5
    • Yasmin, N.1    Bauer, T.2    Modak, M.3    Wagner, K.4    Schuster, C.5    Köfel, R.6    Seyerl, M.7    Stökl, J.8    Elbe-Bürger, A.9    Graf, D.10    Strobl, H.11
  • 52
    • 84859483909 scopus 로고    scopus 로고
    • Differential effects of inhibition of bone morphogenic protein (BMP) signalling on T-cell activation and differentiation
    • Yoshioka, Y., M. Ono, M. Osaki, I. Konishi, and S. Sakaguchi. 2012. Differential effects of inhibition of bone morphogenic protein (BMP) signalling on T-cell activation and differentiation. Eur. J. Immunol. 42: 749-759. http://dx.doi.org/10.1002/eji.201141702
    • (2012) Eur. J. Immunol , vol.42 , pp. 5
    • Yoshioka, Y.1    Ono, M.2    Osaki, M.3    Konishi, I.4    Sakaguchi, S.5
  • 54
    • 79956324551 scopus 로고    scopus 로고
    • L2pB1: a new player in autoimmunity
    • 2010.12.006
    • Zhong, X., and T.L. Rothstein. 2011. L2pB1: a new player in autoimmunity. Mol. Immunol. 48:1292-1300.2010.12.006
    • (2011) Mol. Immunol , vol.48 , pp. 5
    • Zhong, X.1    Rothstein, T.L.2


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