Tumor cell-activated CARD9 signaling contributes to metastasis-associated macrophage polarization

Cell Death and Differentiation

Volumn 21, Issue 8, 2014, Pages 1290-1302

  Yang, M ^a,b   Shao, J H ^c   Miao, Y J ^a,b   Cui, W ^a,b   Qi, Y F ^a,b   Han, J H ^d   Lin, X ^e   Du, J ^a,b  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

^c NANCHANG UNIVERSITY   (China)

^d XIAMEN UNIVERSITY   (China)

^e UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE RECRUITMENT DOMAIN CONTAINING PROTEIN 9; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN; CARD9 PROTEIN, HUMAN; CARD9 PROTEIN, MOUSE; CASPASE RECRUITMENT DOMAIN SIGNALING PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARCINOMA CELL; COLON CARCINOMA; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN TISSUE; LIVER METASTASIS; MACROPHAGE; METASTASIS; MOUSE; NONHUMAN; POLARIZATION; PREDICTIVE VALUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; TUMOR CELL; TUMOR MICROENVIRONMENT; ANIMAL; C57BL MOUSE; CELL COMMUNICATION; COLON TUMOR; METABOLISM; PATHOLOGY; TRANSGENIC MOUSE;

MUS;

ANIMALS; CARD SIGNALING ADAPTOR PROTEINS; CELL COMMUNICATION; COLONIC NEOPLASMS; HUMANS; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEOPLASM METASTASIS; SIGNAL TRANSDUCTION; TUMOR MICROENVIRONMENT;

EID: 84904967052     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2014.45     Document Type: Article

References (40)

1. Hanahan D, Coussens LM. Accessories to the crime: functions of cells recruited to the tumor microenvironment. Cancer Cell 2012; 21: 309-322.
2. Valastyan S, Weinberg RA. Tumor metastasis: molecular insights and evolving paradigms. Cell 2011; 147: 275-292.
3. Mantovani A, Sozzani S, Locati M, Allavena P, Sica A. Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol 2002; 23: 549-555.
4. Solinas G, Germano G, Mantovani A, Allavena P. Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation. J Leukoc Biol 2009; 86: 1065-1073.
5. Condeelis J, Pollard JW. Macrophages: obligate partners for tumor cell migration, invasion, and metastasis. Cell 2006; 124: 263-266.
6. Zaynagetdinov R, Sherrill TP, Polosukhin VV, Han W, Ausborn JA, McLoed AG et al. A critical role for macrophages in promotion of urethane-induced lung carcinogenesis. J Immunol 2011; 187: 5703-5711.
7. Lu-Emerson C, Snuderl M, Kirkpatrick ND, Goveia J, Davidson C, Huang Y et al. Increase in tumor-associated macrophages after antiangiogenic therapy is associated with poor survival among patients with recurrent glioblastoma. Neuro Oncol 2013; 15: 1079-1087.
8. Ohno S, Ohno Y, Suzuki N, Kamei T, Koike K, Inagawa H et al. Correlation of histological localization of tumor-associated macrophages with clinicopathological features in endometrial cancer. Anticancer Res 2004; 24: 3335-3342.
9. Shabo I, Stal O, Olsson H, Dore S, Svanvik J. Breast cancer expression of CD163, a macrophage scavenger receptor, is related to early distant recurrence and reduced patient survival. Int J Cancer 2008; 123: 780-786.
10. Kurahara H, Shinchi H, Mataki Y, Maemura K, Noma H, Kubo F et al. Significance of M2-polarized tumor-associated macrophage in pancreatic cancer. J Surg Res 2011; 167: e211-e219.
11. Lee CH, Espinosa I, Vrijaldenhoven S, Subramanian S, Montgomery KD, Zhu S et al. Prognostic significance of macrophage infiltration in leiomyosarcomas. Clin Cancer Res 2008; 14: 1423-1430.
12. Komohara Y, Ohnishi K, Kuratsu J, Takeya M. Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas. J Pathol 2008; 216: 15-24.
13. Qian B, Deng Y, Im JH, Muschel RJ, Zou Y, Li J et al. A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth. PLoS One 2009; 4: e6562.
14. Qian BZ, Pollard JW. Macrophage diversity enhances tumor progression and metastasis. Cell 2010; 141: 39-51.
15. Ruland J. CARD9 signaling in the innate immune response. Ann N Y Acad Sci 2008; 1143: 35-44.
16. Hsu YM, Zhang Y, You Y, Wang D, Li H, Duramad O et al. The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens. Nat Immunol 2007; 8: 198-205.
17. Nakamura S, Matsumoto T, Yada S, Hirahashi M, Suekane H, Yao T et al. Overexpression of caspase recruitment domain (CARD) membrane-associated guanylate kinase 1 (CARMA1) and CARD9 in primary gastric B-cell lymphoma. Cancer 2005; 104: 1885-1893.
18. Zhou Y, Ye H, Martin-Subero JI, Hamoudi R, Lu YJ, Wang R et al. Distinct comparative genomic hybridisation profiles in gastric mucosa-associated lymphoid tissue lymphomas with and without t(11;18)(q21;q21). Br J Haematol 2006; 133: 35-42.
19. Ullrich E, Bonmort M, Mignot G, Kroemer G, Zitvogel L. Tumor stress, cell death and the ensuing immune response. Cell Death Differ 2008; 15: 21-28.
20. Joyce JA, Pollard JW. Microenvironmental regulation of metastasis. Nat Rev Cancer 2009; 9: 239-252.
21. Qian BZ, Li J, Zhang H, Kitamura T, Zhang J, Campion LR et al. CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis. Nature 2011; 475: 222-225.
22. Qing W, Fang WY, Ye L, Shen LY, Zhang XF, Fei XC et al. Density of tumor-associated macrophages correlates with lymph node metastasis in papillary thyroid carcinoma. Thyroid 2012; 22: 905-910.
23. Obeid E, Nanda R, Fu YX, Olopade OI. The role of tumor-associated macrophages in breast cancer progression (review). Int J Oncol 2013; 43: 5-12.
24. Bailey C, Negus R, Morris A, Ziprin P, Goldin R, Allavena P et al. Chemokine expression is associated with the accumulation of tumour associated macrophages (TAMs) and progression in human colorectal cancer. Clin Exp Metastasis 2007; 24: 121-130.
25. Ishigami S, Natsugoe S, Tokuda K, Nakajo A, Okumura H, Matsumoto M et al. Tumor-associated macrophage (TAM) infiltration in gastric cancer. Anticancer Res 2003; 23: 4079-4083.
26. Martinez FO, Helming L, Gordon S. Alternative activation of macrophages: an immunologic functional perspective. Annu Rev Immunol 2009; 27: 451-483.
27. Jaiswal S, Jamieson CH, Pang WW, Park CY, Chao MP, Majeti R et al. CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis. Cell 2009; 138: 271-285.
28. Roca H, Varsos ZS, Sud S, Craig MJ, Ying C, Pienta KJ. CCL2 and interleukin-6 promote survival of human CD11b + peripheral blood mononuclear cells and induce M2-type macrophage polarization. J Biol Chem 2009; 284: 34342-34354.
29. Mantovani A, Allavena P, Sica A, Balkwill F. Cancer-related inflammation. Nature 2008; 454: 436-444.
30. Solinas G, Schiarea S, Liguori M, Fabbri M, Pesce S, Zammataro L et al. Tumor-conditioned macrophages secrete migration-stimulating factor: a new marker for M2-polarization, influencing tumor cell motility. J Immunol 2010; 185: 642-652.
31. Chang CP, Su YC, Hu CW, Lei HY. TLR2-dependent selective autophagy regulates NF-kappaB lysosomal degradation in hepatoma-derived M2 macrophage differentiation. Cell Death Differ 2013; 20: 515-523.
32. DeNardo DG, Barreto JB, Andreu P, Vasquez L, Tawfik D, Kolhatkar N et al. CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages. Cancer Cell 2009; 16: 91-102.
33. Hagemann T, Lawrence T, McNeish I, Charles KA, Kulbe H, Thompson RG et al. "Re-educating" tumor-associated macrophages by targeting NF-kappaB. J Exp Med 2008; 205: 1261-1268.
34. Gross O, Gewies A, Finger K, Schafer M, Sparwasser T, Peschel C et al. Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity. Nature 2006; 442: 651-656.
35. Bi L, Gojestani S, Wu W, Hsu YM, Zhu J, Ariizumi K et al. CARD9 mediates dectin-2-induced IkappaBalpha kinase ubiquitination leading to activation of NF-kappaB in response to stimulation by the hyphal form of Candida albicans. J Biol Chem 2010; 285: 25969-25977.
36. Mocsai A, Ruland J, Tybulewicz VL. The SYK tyrosine kinase: a crucial player in diverse biological functions. Nat Rev Immunol 2010; 10: 387-402.
37. Issa A, Le TX, Shoushtari AN, Shields JD, Swartz MA. Vascular endothelial growth factor-C and C-C chemokine receptor 7 in tumor cell-lymphatic cross-talk promote invasive phenotype. Cancer Res 2009; 69: 349-357.
38. Morimoto-Tomita M, Ohashi Y, Matsubara A, Tsuiji M, Irimura T. Mouse colon carcinoma cells established for high incidence of experimental hepatic metastasis exhibit accelerated and anchorage-independent growth. Clin Exp Metastasis 2005; 22: 513-521.
39. Lammers B, Chandak PG, Aflaki E, Van Puijvelde GH, Radovic B, Hildebrand RB et al. Macrophage adipose triglyceride lipase deficiency attenuates atherosclerotic lesion development in low-density lipoprotein receptor knockout mice. Arterioscler Thromb Vasc Biol 2011; 31: 67-73.
40. Yang M, Zheng J, Miao Y, Wang Y, Cui W, Guo J et al. Serum-glucocorticoid regulated kinase 1 regulates alternatively activated macrophage polarization contributing to angiotensin II-induced inflammation and cardiac fibrosis. Arterioscler Thromb Vasc Biol 2012; 32: 1675-1686.