Vitamin A induces inhibitory histone methylation modifications and down-regulates trained immunity in human monocytes

Journal of Leukocyte Biology

Volumn 98, Issue 1, 2015, Pages 129-136

  Arts, Rob J W ^a   Blok, Bastiaan A ^a,b,c   van Crevel, Reinout ^a   Joosten, Leo A B ^a   Aaby, Peter ^b   Benn, Christine Stabell ^b,c   Netea, Mihai G ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b STATENS SERUM INSTITUT   (Denmark)

^c UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

Cytokines; Epigenomics; Heterologous immunity; Macrophage; Retinoic acid

Indexed keywords

BCG VACCINE; CYTOKINE; HISTONE METHYLTRANSFERASE; MESSENGER RNA; RETINOIC ACID; RETINOL; HISTONE;

ARTICLE; BCG VACCINATION; CELL DEATH; CONSTITUTIVE HETEROCHROMATIN; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; DOWN REGULATION; GENE EXPRESSION; HETEROCHROMATIN; HISTONE METHYLATION; HISTONE MODIFICATION; HUMAN; HUMAN CELL; IMMUNITY; INNATE IMMUNITY; LEUKOCYTE; MACROPHAGE; MONOCYTE; MYCOBACTERIUM BOVIS BCG; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WILCOXON SIGNED RANKS TEST; CELL CULTURE; CHROMATIN IMMUNOPRECIPITATION; DRUG EFFECTS; IMMUNOLOGY; METABOLISM; METHYLATION; WESTERN BLOTTING;

BLOTTING, WESTERN; CELLS, CULTURED; CHROMATIN IMMUNOPRECIPITATION; DOWN-REGULATION; HISTONES; HUMANS; IMMUNITY, INNATE; METHYLATION; MONOCYTES; TRETINOIN;

EID: 84934759229     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.6AB0914-416R     Document Type: Article

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