Dehydropyrrolizidine alkaloid toxicity, cytotoxicity, and carcinogenicity

Toxins

Volumn 8, Issue 12, 2016, Pages

  Stegelmeier, Bryan L ^a   Colegate, Steven M ^a,b   Brown, Ammon W ^c  

^a U S DEPARTMENT OF AGRICULTURE   (United States)

^b UTAH STATE UNIVERSITY   (United States)

^c US ARMY INSTITUTE OF SURGICAL RESEARCH   (United States)

Author keywords

Alkaloids; Carcinogenesis; Dehydropyrrolizidine; DHPA; PA; Pyrrolizidine; Pyrrolizidine alkaloid induced cytotoxicity; Toxic hepatopathy; Toxic plant

Indexed keywords

DEHYDROPYRROLIZIDINE ALKALOID; ECHIMIDINE; HELIOTRINE; HELIOTRINE MONO ESTER HELIOTRIDINE; INTERMEDINE; INTERMEDINE MONO ESTER RETRONECINE; LASIOCARPINE; LASIOCARPINE DIESTER HELIOTRIDINE; LASIOCARPINE N OXIDE; LYCOPSAMINE; LYCOPSAMINE MONO ESTER RETRONECINE; MONOCROTALINE; MONOCROTALINE MACROCYCLIC RETRONECINE; PROTEIN P53; PYRROLIZIDINE ALKALOID; RETRONECINE; RIDDELLIINE; RIDDELLIINE MACROCYCLIC RETRONECINE; SENECIONINE; SENECIONINE MACROCYCLIC RETRONECINE; SENECIONINE N OXIDE; SENECIPHYLLINE; SENECIPHYLLINE MACROCYCLIC RETRONECINE; UNCLASSIFIED DRUG; CARCINOGEN;

BIOASSAY; CARCINOGENICITY; CHICKEN; CYTOTOXICITY; DIAGNOSTIC PROCEDURE; EXPOSURE; HUMAN; INTOXICATION; LD50; LIVER CELL CARCINOMA; LIVER CELL CULTURE; LIVESTOCK; METABOLIC ACTIVATION; NONHUMAN; PHYTOTOXICITY; REVIEW; RISK ASSESSMENT; TOXICITY TESTING; TOXICOKINETICS; ANIMAL; CELL SURVIVAL; DRUG EFFECTS;

ANIMALS; CARCINOGENS; CELL SURVIVAL; HUMANS; PYRROLIZIDINE ALKALOIDS;

EID: 85002141917     PISSN: None     EISSN: 20726651     Source Type: Journal    
DOI: 10.3390/toxins8120356     Document Type: Review

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